The role of b-type natriuretic peptide in heart failure management

Journal article

Newton, Phillip, Betihavas, Vasiliki and Macdonald, Peter. (2009). The role of b-type natriuretic peptide in heart failure management. Australian Critical Care. 22(3), pp. 117-123. https://doi.org/10.1016/j.aucc.2009.06.001
AuthorsNewton, Phillip, Betihavas, Vasiliki and Macdonald, Peter
Abstract

Heart failure is a complex clinical syndrome that manifests itself with signs and symptoms which are neither sensitive nor specific for the diagnosis of heart failure. Natriuretic peptides and in particular b-type natriuretic peptide (and nt-proBNP) are widely used in clinical practice around the world as a maker of heart failure. BNP is primarily released from the left ventricle in response to pressure and volume overload. The strongest evidence for the use of BNP is to rule in or rule out heart failure as cause of breathlessness in people who present to the emergency room. There is enthusiasm for use of BNP as a marker of heart failure severity as well as a predictor of outcomes in people with heart failure and trials are ongoing. Nesiritide, a recombinant form of BNP is currently being tested as a possible treatment in people with acutely decompensated heart failure.

KeywordsHeart failure; b-Type natriuretic peptide
Year01 Jan 2009
JournalAustralian Critical Care
Journal citation22 (3), pp. 117-123
PublisherElsevier
ISSN1036-7314
Digital Object Identifier (DOI)https://doi.org/10.1016/j.aucc.2009.06.001
Web address (URL)https://www.australiancriticalcare.com/article/S1036-7314(09)00086-1/abstract#articleInformation
Open accessPublished as non-open access
Research or scholarlyResearch
Page range117-123
Author's accepted manuscript
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Open
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Controlled
Output statusPublished
Publication dates
Online09 Jul 2009
Publication process dates
Accepted04 Jun 2009
Deposited03 May 2024
Additional information

© 2009 Australian College of Critical Care Nurses Ltd. Published by Elsevier Inc. All rights reserved.

Place of publicationIreland
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