Comparison of the Lactate Pro, Lactate Pro 2 and i-STAT portable blood lactate analysers

Journal article

Rowe, Grant S. and Whyte, Douglas G.. (2016). Comparison of the Lactate Pro, Lactate Pro 2 and i-STAT portable blood lactate analysers. Gazzetta Medica Italiana Archivio per le Scienze Mediche. 175(9), pp. 378-383.
AuthorsRowe, Grant S. and Whyte, Douglas G.
Abstract

Background: To evaluate the accuracy of blood lactate measurements using the Lactate Pro (LP), Lactate Pro 2 (LP2) portable lactate analyzers and i-STAT point-of-care device.

Methods: Blood samples (N.=284) were taken from 28 subjects during a variety of exercise modes: incremental cycling test, team-sport running simulation or resistance training. Weighted least products regression analysis was used to compare the LP to LP2 and LP2 to i-STAT.

Results: Lactate concentrations ranged between 0.4-18.2 mM. There was a strong linear relationship observed between the LP and LP2 analyzers (r=0.976, P<0.01), although a small proportional bias was apparent. A strong linear relationship was also found between the LP2 and i-STAT analyzers; however, both a fixed and proportional bias were revealed. The i-STAT reported higher absolute lactate concentrations (mean ± SD, 1.4±1.3 mM, P<0.001) which became more marked at moderate to high concentrations (>4 mM; 2.2±1.0 mM, P<0.001).

Conclusions: While strong linear relationships existed between all three analyzers, the LP and LP2 reported substantially lower lactate values compared with the i-STAT, especially at higher lactate concentrations. These results further highlight the need for caution when interpreting or comparing lactate data obtained using different analyzers.

Keywordslactate; lactate analysis; point-of-care testing
Year2016
JournalGazzetta Medica Italiana Archivio per le Scienze Mediche
Journal citation175 (9), pp. 378-383
PublisherEdizioni Minerva Medica
ISSN0393-3660
Scopus EID2-s2.0-84989867059
Web address (URL)https://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article.php?cod=R22Y2016N09A0378&acquista=1
Open accessPublished as green open access
Research or scholarlyResearch
Page range378-383
Research GroupSports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre
Author's accepted manuscript
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Place of publicationItaly
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