Integrative biology of exercise
Journal article
Hawley, John A., Hargreaves, Mark, Joyner, Michael J. and Zierath, Juleen R.. (2014). Integrative biology of exercise. Cell. 159(6), pp. 738 - 749. https://doi.org/10.1016/j.cell.2014.10.029
Authors | Hawley, John A., Hargreaves, Mark, Joyner, Michael J. and Zierath, Juleen R. |
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Abstract | Exercise represents a major challenge to whole-body homeostasis provoking widespread perturbations in numerous cells, tissues, and organs that are caused by or are a response to the increased metabolic activity of contracting skeletal muscles. To meet this challenge, multiple integrated and often redundant responses operate to blunt the homeostatic threats generated by exercise-induced increases in muscle energy and oxygen demand. The application of molecular techniques to exercise biology has provided greater understanding of the multiplicity and complexity of cellular networks involved in exercise responses, and recent discoveries offer perspectives on the mechanisms by which muscle “communicates” with other organs and mediates the beneficial effects of exercise on health and performance. |
Year | 2014 |
Journal | Cell |
Journal citation | 159 (6), pp. 738 - 749 |
Publisher | Cell Press |
ISSN | 0092-8674 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.cell.2014.10.029 |
Scopus EID | 2-s2.0-84909979604 |
Page range | 738 - 749 |
Research Group | Sports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre |
Publisher's version | File Access Level Controlled |
Place of publication | United States of America |
https://acuresearchbank.acu.edu.au/item/85673/integrative-biology-of-exercise
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