Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia

Journal article


Reginster, Jean Yves, Cooper, Cyrus, Rizzoli, Rene, Kanis, John A., Appelboom, Geoff, Bautmans, Ivan, Bischoff-Ferrari, Heike A., Boers, Maarten, Brandi, Maria Luisa, Bruyère, Olivier, Cherubini, Antonio, Flamion, Bruno, Fielding, Roger A., Gasparik, Andrea Ildiko, Van Loon, Lucas, McCloskey, Eugene, Mitlak, Bruce, Pilotto, Alberto, Reiter-Niesert, Suzanne, ... Cruz-Jentoft, Alfonso J.. (2016) Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clinical and Experimental Research. https://doi.org/10.1007/s40520-015-0517-y
AuthorsReginster, Jean Yves, Cooper, Cyrus, Rizzoli, Rene, Kanis, John A., Appelboom, Geoff, Bautmans, Ivan, Bischoff-Ferrari, Heike A., Boers, Maarten, Brandi, Maria Luisa, Bruyère, Olivier, Cherubini, Antonio, Flamion, Bruno, Fielding, Roger A., Gasparik, Andrea Ildiko, Van Loon, Lucas, McCloskey, Eugene, Mitlak, Bruce, Pilotto, Alberto, Reiter-Niesert, Suzanne, Rolland, Yves, Tsouderos, Yannis, Visser, Marjolein and Cruz-Jentoft, Alfonso J.
Abstract

Purpose Sarcopenia is an age-related muscle condition which is frequently a precursor of frailty, mobility disability and premature death. It has a high prevalence in older populations and presents a considerable social and economic burden. Potential treatments are under development but, as yet, no guidelines support regulatory studies for new drugs to manage sarcopenia. The objective of this position paper is therefore to suggest a set of potential endpoints and target population definitions to stimulate debate and progress within the medico-scientific and regulatory communities. Methods A multidisciplinary expert working group was hosted by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, which reviewed and discussed the recent literature from a perspective of clinical experience and guideline development. Relevant parallels were drawn from the development of definition of osteoporosis as a disease and clinical assessment of pharmaceutical treatments for that indication. Results A case-finding decision tree is briefly reviewed with a discussion of recent prevalence estimations of different relevant threshold values. The selection criteria for patients in regulatory studies are discussed according to the aims of the investigation (sarcopenia prevention or treatment) and the stage of project development. The possible endpoints of such studies are reviewed and a plea is made for the establishment of a core outcome set to be used in all clinical trials of sarcopenia. Conclusions The current lack of guidelines for the assessment of new therapeutic treatments for sarcopenia could potentially hinder the delivery of effective medicines to patients at risk.

KeywordsClinical trials; Sarcopenia; Public health; Preventative health care; Frailty
Year2016
JournalAging Clinical and Experimental Research
Digital Object Identifier (DOI)https://doi.org/10.1007/s40520-015-0517-y
Research GroupMary MacKillop Institute for Health Research
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McCloskey, Eugene, Leslie, William D. and Kanis, John. (2018) Assessment of fracture risk. In In N. C. Harvey and C. Cooper (Ed.). Osteoporosis: A lifecourse epidemiology approach to skeletal health pp. 163 - 176 CRC Press. https://doi.org/10.1201/9781351234627
Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score (TBS): The Manitoba BMD registry
Leslie, William D., Shevroja, E., Johansson, Helena, McCloskey, Eugene, Harvey, Nicholas C., Kanis, John A. and Hans, Didier. (2018) Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score (TBS): The Manitoba BMD registry. Osteoporosis International. 29(3), pp. 751 - 758. https://doi.org/10.1007/s00198-018-4405-0
A novel in vitro model for the assessment of postnatal myonuclear accretion
Kneppers, Anita, Verdijk, Lex B., de Theije, Chiel, Corten, Mark, Gielen, Ellis, van Loon, Luc, Schols, Annemie and Langen, Ramon. (2018) A novel in vitro model for the assessment of postnatal myonuclear accretion. Skeletal Muscle. 8(4), pp. 1 - 13. https://doi.org/10.1186/s13395-018-0151-4
Pitfalls in the measurement of muscle mass: A need for a reference standard
Buckinx, Fanny, Landi, Francesco, Cesari, Matteo, Fielding, Roger A., Visser, Marjolein, Engelke, Klaus, Maggi, Stefania, Dennison, Elaine, Al-Daghri, Nasser M., Allepaerts, Sophie, Bauer, Jurgen, Bautmans, Ivan, Brandi, Maria Luisa, Bruyère, Olivier, Cederholm, Tommy, Cerreta, Francesca, Cherubini, Antonio, Cooper, Cyrus, Cruz-Jentoft, Alphonso, ... Kanis, John A.. (2018) Pitfalls in the measurement of muscle mass: A need for a reference standard. Journal of Cachexia, Sarcopenia and Muscle. 9(2), pp. 269 - 278. https://doi.org/10.1002/jcsm.12268
Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers
Johansson, Helena, Vala, C. H., Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene, Kanis, John, Harvey, Nicholas C., Ohlsson, Claes, Lohmander, L. S., Karrholm, J. and Mellstrom, D.. (2018) Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers. Osteoporosis International. 29(3), pp. 741 - 749. https://doi.org/10.1007/s00198-017-4355-y
Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation
Rizzoli, Rene, Biver, Emmanuel, Bonjour, J. P., Coxam, V., Goltzman, D., Kanis, John, Lappe, J., Rejnmark, Lars, Sahni, S., Weaver, C., Weiler, H. and Reginster, J. Y.. (2018) Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation. Osteoporosis International. 29(9), pp. 1933 - 1948. https://doi.org/10.1007/s00198-018-4534-5
Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men
Holwerda, Andrew M., Overkamp, Maarten, Paulussen, Kevin J. M., Smeets, Joey S. J., Van Kranenburg, Janneau, Backx, E. M. P., Gijsen, Annemie P., Goessens, Joy P. B., Verdijk, Lex B. and van Loon, Luc. (2018) Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men. The Journal of Nutrition. 148(11), pp. 1723 - 1732. https://doi.org/10.1093/jn/nxy169
A health economic simulation model for the clinical management of osteoporosis
Jonsson, E., Hansson-Hedblom, A., Ljunggren, Östen, Åkesson, K., Spångeus, A., Kanis, John and Borgström, F.. (2018) A health economic simulation model for the clinical management of osteoporosis. Osteoporosis International. 29(3), pp. 545 - 555. https://doi.org/10.1007/s00198-017-4325-4
Protein content and amino acid composition of commercially available plant-based protein isolates
Gorissen, Stefan H. M., Crombag, Julie J. R., Senden, Joan M., Huub Waterval, W. A., Bierau, Jörgen, Verdijk, Lex B. and van Loon, Luc. (2018) Protein content and amino acid composition of commercially available plant-based protein isolates. Amino Acids. 50(12), pp. 1685 - 1695. https://doi.org/10.1007/s00726-018-2640-5
Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men
Backx, E. M. P., Horstman, Astrid M. H., Marzuca-Nassr, Gabriel N., Van Kranenburg, Janneau, Smeets, Joey S. J., Fuchs, Cas J., Janssen, Anniek A. W., de Groot, Lisette C. P. G. M., Snijders, Tim, Verdijk, Lex B. and van Loon, Luc. (2018) Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men. Nutrients. 10(635), pp. 1 - 12. https://doi.org/10.3390/nu10050635
Application of FRAX to determine the risk of osteoporotic fractures in the Ukrainian population
Povoroznyuk, V. V., Grygorieva, Nataliia V., McCloskey, Eugene, Johansson, Helena and Kanis, John. (2018) Application of FRAX to determine the risk of osteoporotic fractures in the Ukrainian population. International Journal of Osteoporosis and Metabolic Disorders. 11(1), pp. 7 - 13. https://doi.org/10.3923/ijom.2018.7.13
Brain tissue plasticity: protein synthesis rates of the human brain0006
Smeets, Joey S. J., Horstman, Astrid M. H., Schijns, Olaf E. M. G., Dings, Jim T. A., Hoogland, Govert, Gijsen, Annemie P., Goessens, Joy P. K., Bouwman, Freek G., Wodzig, Will K. W. H., Mariman, Edwin C. and Van Loon, Luc. (2018) Brain tissue plasticity: protein synthesis rates of the human brain0006. Brain: a journal of neurology. 141(4), pp. 1122 - 1129. https://doi.org/10.1093/brain/awy015
Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients
Hansen, Dominique, Verboven, Kenneth, van Dijk, Jan Willem, Zorenc, Antoine H., Minten, Lennert, Smeets, Kevin, Verdijk, Lex B. and Van Loon, Luc. (2018) Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients. European Journal of Sport Science. 18(9), pp. 1245 - 1254. https://doi.org/10.1080/17461391.2018.1483428
Characteristics of recurrent fractures
Kanis, John A., Johansson, Helena, Odén, Anders, Harvey, Nicholas C., Gudnason, V., Sanders, Kerrie, Sigurdsson, Gunnar, Siggeirsdottir, K., Fitzpatrick, Lorraine A., Borgström, F. and McCloskey, Eugene. (2018) Characteristics of recurrent fractures. Osteoporosis International. 29(8), pp. 1747 - 1757. https://doi.org/10.1007/s00198-018-4502-0
Understanding osteoporotic pain and its pharmacological treatment
Vellucci, R., Terenzi, R., Kanis, John, Kress, H. G., Mediati, R. D., Reginster, J. Y., Rizzoli, Rene and Brandi, Maria Luisa. (2018) Understanding osteoporotic pain and its pharmacological treatment. Osteoporosis International. 29(7), pp. 1477 - 1491. https://doi.org/10.1007/s00198-018-4476-y
Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats
Monaco, Cynthia, Miotto, Paula M., Huber, Jason S., Van Loon, Luc, Simpson, Jeremy A. and Holloway, Graham P.. (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315(2), pp. 191 - 204. https://doi.org/10.1152/ajpregu.00275.2017
Health-related quality of life during the first year after a hip fracture: Results of the Mexican arm of the International Cost and Utility Related to Osteoporotic Fractures Study (MexICUROS)
Guirant, L., Carlos, Fernando, Curiel, D., Kanis, John A., Borgström, Frederick, Svedbom, Axel and Clark, Patricia. (2018) Health-related quality of life during the first year after a hip fracture: Results of the Mexican arm of the International Cost and Utility Related to Osteoporotic Fractures Study (MexICUROS). Osteoporosis International. 29(5), pp. 1147 - 1154. https://doi.org/10.1007/s00198-018-4389-9
Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture
Malafarina, Vincenzo, Reginster, J. Y., Cabrerizo, Sonia, Bruyère, Olivier, Kanis, John A., Martinez, J. Alfredo and Zulet, M. Angeles. (2018) Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture. Nutrients. 10(5), pp. 1 - 26. https://doi.org/10.3390/nu10050555
The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease
Beijers, Rosanne J. H. C. G., Huysmans, Stephanie M. D., van de Bool, Coby, Kingma, Boris R. M., Verdijk, Lex B., Van Loon, Luc, Meex, Steven J. R., Gosker, Harry R. and Schols, Annemie M. W. J.. (2018) The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease. Clinical Nutrition. 37(6), pp. 1852 - 1861. https://doi.org/10.1016/j.clnu.2017.10.011
Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes
Jonvik, Kristin L., Nyakayiru, Jean, van Dijk, Jan Willem, Maase, K., Ballak, S. B., Senden, Joan M., van Loon, Luc and Verdijk, Lex B.. (2018) Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes. European Journal of Sport Science. 18(4), pp. 524 - 533. https://doi.org/10.1080/17461391.2018.1433722
Review of the guideline of the American College of Physicians on the treatment of osteoporosis
Kanis, J. A., Cooper, C., Rizzoli, R. and Reginster, J.-Y.. (2018) Review of the guideline of the American College of Physicians on the treatment of osteoporosis. Osteoporosis International. 29(7), pp. 1505 - 1510. https://doi.org/10.1007/s00198-018-4504-y
Does nutrition play a role in the prevention and management of sarcopenia?
Robinson, S. M., Reginster, J. Y., Rizzoli, R., Shaw, S. C., Kanis, J. A., Bautmans, I., Bischoff-Ferrari, H., Bruyère, O., Cesari, M., Dawson-Hughes, B., Fielding, R. A., Kaufman, J. M., Landi, F., Malafarina, Vincenzo, Rolland, Y., van Loon, L. J., Vellas, B., Visser, M. and Cooper, C.. (2018) Does nutrition play a role in the prevention and management of sarcopenia? Clinical Nutrition. 37(4), pp. 1121 - 1132. https://doi.org/10.1016/j.clnu.2017.08.016
Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET
Smeets, Joey S.J. and Van Loon, Luc. (2018) Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET. Brain: a journal of neurology. 141(7), pp. 52 - 52. https://doi.org/10.1093/brain/awy119
Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial
Shepstone, L., Lenaghan, E., Cooper, C., Clarke, Shane, Fong-Soe-Khioe, Rebekah, Fordham, R., Gittoes, Neil, Harvey, Ian, Harvey, Nicholas C., Heawood, A., Holland, R., Howe, A., Kanis, John, Marshall, Tarnya, O'Neill, T. W., Peters, T. J., Redmond, Niamh, Torgerson, David, Turner, David and McCloskey, Eugene. (2018) Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial. The Lancet. 391(10122), pp. 741 - 747. https://doi.org/10.1016/S0140-6736(17)32640-5
Performance of FRAX in clinical practice according to sex and osteoporosis definitions: The Manitoba BMD registry
Leslie, William D., Majumdar, S. R., Morin, Suzanne N., Lix, Lisa, Schousboe, J. T., Ensrud, K. E., Johansson, Helena, McCloskey, Eugene and Kanis, John A.. (2018) Performance of FRAX in clinical practice according to sex and osteoporosis definitions: The Manitoba BMD registry. Osteoporosis International. 29(3), pp. 759 - 767. https://doi.org/10.1007/s00198-018-4415-y
Detection of localized hepatocellular amino acid kinetics by using mass spectrometry imaging of stable isotopes
Arts, Martijn, Soons, Zita, Ellis, Shane R., Pierzchalski, Keely A., Balluff, Benjamin, Eijkel, Gert B., Dubois, Ludwig J., Lieuwes, Natasja G., Agten, Stijn M., Hackeng, Tilman M., Van Loon, Luc, Heeren, Ron M.A. and Damink, Steven W.O.. (2017) Detection of localized hepatocellular amino acid kinetics by using mass spectrometry imaging of stable isotopes. Angewandte Chemie. 56(25), pp. 7146 - 7150. https://doi.org/10.1002/anie.201702669
Mind the (treatment) gap: A global perspective on current and future strategies for prevention of fragility fractures
Harvey, N. C., McCloskey, E. V., Mitchell, P. J., Dawson-Hughes, B., Pierroz, D. D., Reginster, J.-Y. Yves, Rizzoli, R., Cooper, C. and Kanis, J. A.. (2017) Mind the (treatment) gap: A global perspective on current and future strategies for prevention of fragility fractures. Osteoporosis International. 28(5), pp. 1507 - 1529. https://doi.org/10.1007/s00198-016-3894-y
Post-exercise muscle glycogen resynthesis in humans
Burke, Louise M., van Loon, Luc and Hawley, John Alan. (2017) Post-exercise muscle glycogen resynthesis in humans. Journal of Applied Physiology. 122(5), pp. 1055 - 1067. https://doi.org/0.1152/japplphysiol.00860.2016
The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: individual participant data and meta-analysis of rct's
Tieland, Michael, Franssen, Rinske, Dullemeijer, C., van Dronkelaar, C., Kim, H. K., Ispoglou, T., Zhu, Kun, Prince, R. L., Van Loon, Luc and de Groot, Lisette C.P.G.M.. (2017) The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: individual participant data and meta-analysis of rct's. Journal of Nutrition, Health and Aging. 21(9), pp. 994 - 1001. https://doi.org/10.1007/s12603-017-0896-1
Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: Research for evidence and a scientific statement from the European society for clinical and economic aspects of osteopo
Cianferotti, Luisella, Bertoldo, Francesco, Bischoff-Ferrari, Heike A., Bruyere, O., Cooper, Cyrus, Cutolo, Maurizio, Kanis, John A., Kaufman, Jean-Marc, Reginster, Jean-Yves, Rizzoli, Rene and Brandi, Maria Luisa. (2017) Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: Research for evidence and a scientific statement from the European society for clinical and economic aspects of osteopo. Endocrine. 56(2), pp. 245 - 261. https://doi.org/10.1007/s12020-017-1290-9
Erratum to: diacerein: benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO
Pavelka, Karel, Bruyère, O., Cooper, Cyrus, Kanis, John, Leeb, Burkhard F., Maheu, E., Martel-Pelletier, Johanne, Monfort, Jordi, Pelletier, Jean P., Rizzoli, Rene and Reginster, Jean Yves. (2017) Erratum to: diacerein: benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO. Drugs and Aging. 34(5), pp. 413 - 413. https://doi.org/10.1007/s40266-017-0457-7
Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD Cohort
Martineau, Patrick, Leslie, William, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Hans, Didier and Kanis, John. (2017) Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD Cohort. Journal of Bone and Mineral Research. 32(7), pp. 1568 - 1574. https://doi.org/10.1002/jbmr.3124
Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS
Svedbom, A., Borgström, Fredrik, Hernlund, E., Ström, O., Alekna, V., Bianchi, Maria L., Clark, P., Curiel, M. D., Dimai, Hans P., Jürisson, M., Uusküla, A., Lember, M., Kallikorm, R., Lesnyak, Olga, McCloskey, Eugene, Ershova, Olga, Sanders, Kerrie, Silverman, S., Tamulaitiene, M., ... Kanis, John. (2017) Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS. Quality of Life Research. 27(3), pp. 707 - 716. https://doi.org/10.1007/s11136-017-1748-5
Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis
Dirks, Marlou L., Groen, Bart B.L., Franssen, Rinske, van Kranenburg, Janneau and Van Loon, Luc. (2017) Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis. Journal of Applied Physiology. 122(1), pp. 20 - 27. https://doi.org/10.1152/japplphysiol.00331.2016
Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK: an analysis of anonymous website activity
McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Compston, Juliet E. and Kanis, J.. (2017) Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK: an analysis of anonymous website activity. Osteoporosis International. 28(1), pp. 71 - 76. https://doi.org/10.1007/s00198-016-3696-2
Erratum to: can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, O., Cooper, Cyrus, Arden, Nigel, Branco, J., Brandi, Maria L., Herrero-Beaumont, G., Berenbaum, F., Dennison, Elaine M., Devogelaer, J. P., Hochberg, Marc, Kanis, John, Laslop, A., McAlindon, T., Reiter, Susanne, Richette, P., Rizzoli, Rene and Reginster, Jean Y.. (2017) Erratum to: can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis. Drugs and Aging. 34(5), pp. 411 - 411. https://doi.org/10.1007/s40266-017-0456-8
Increased risk of hip fracture among spouses-evidence of a homogamy effect
Vala, C. H., Oden, Anders, Lorentzon, Mattias, Sundh, V., Johansson, Helena, Karlsson, Magnus, Rosengren, Björn E., Ohlsson, Claes, Johansson, B., Kanis, John and Mellström, Dan. (2017) Increased risk of hip fracture among spouses-evidence of a homogamy effect. Osteoporosis International. 28(1), pp. 95 - 102. https://doi.org/10.1007/s00198-016-3738-9
Total hip bone area affects fracture prediction with FRAX® in Canadian white women
Leslie, William D., Lix, Lisa, Majumdar, S. R., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2017) Total hip bone area affects fracture prediction with FRAX® in Canadian white women. Journal of Clinical Endocrinology and Metabolism. 102(11), pp. 4242 - 4249. https://doi.org/10.1210/jc.2017-01327
Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans
Snijders, Tim, Nederveen, Joshua P., Verdijk, Lex B., Houben, Alfons J.H.M., Goossens, Gijs H., Parise, Gianna and Van Loon, Luc. (2017) Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans. Physiological Reports. 5(10), pp. 1 - 5. https://doi.org/10.14814/phy2.13278
International osteoporosis foundation and European calcified tissue society working group. Recommendations for the screening of adherence to oral bisphosphonates
Diez-Perez, Aldolfo, Naylor, K. E., Abrahamsen, Bo, Agnusdei, D., Brandi, Maria L., Cooper, Cyrus, Dennison, Elaine M., Eriksen, E. F., Gold, D. T., Guañabens, N., Hadji, P., Hiligsmann, Mickaël, Horne, R., Josse, R. G., Kanis, John, Obermayer-Pietsch, Barbara, Prieto-Alhambra, D., Reginster, Jean Y., Rizzoli, Rene, ... Eastell, Richard. (2017) International osteoporosis foundation and European calcified tissue society working group. Recommendations for the screening of adherence to oral bisphosphonates. Osteoporosis International. 28(3), pp. 767 - 774. https://doi.org/10.1007/s00198-017-3906-6
Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting
Kanis, J. A., Cooper, C., Rizzoli, R., Abrahamsen, B., Al-Daghri, N. M., Brandi, M. L., Cannata-Andia, J., Cortet, B., Dimai, H. P., Ferrari, S., Hadji, P., Harvey, N. C., Kraenzlin, M., Kurth, A., McCloskey, E., Minisola, S., Thomas, T. and Reginster, J.-Y.. (2017) Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting. Osteoporosis International. 28(7), pp. 2023 - 2034. https://doi.org/10.1007/s00198-017-4009-0
Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate
Lesnyak, Olga, Sahakyan, S., Zakroyeva, A., Bilezikian, John P., Hutchings, N., Babalyan, V., Galstyan, R., Lebedev, A., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene and Kanis, John. (2017) Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate. Archives of Osteoporosis. 12(98), pp. 1 - 9. https://doi.org/10.1007/s11657-017-0392-6
Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures - results from the ICUROS
Svedbom, A., Borgstom, F., Hernlund, E., Strom, Oskar, Alekna, V., Bianchi, Maria L., Clark, Patricia M., Curiel, M. D., Dimai, Hans P., Jurisson, Mikk, Kallikorm, R., Lember, M., Lesnyak, Olga, McCloskey, Eugene, Sanders, Kerry M., Silverman, S., Solodovnikov, A., Tamulaitiene, M., Thomas, T., ... Kanis, John. (2017) Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures - results from the ICUROS. Osteoporosis International. 29(3), pp. 557 - 566. https://doi.org/10.1007/s00198-017-4317-4
FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry
Leslie, William, Majumdar, S. R., Morin, Suzanne N., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2017) FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry. Osteoporosis International. 28(9), pp. 2557 - 2564. https://doi.org/10.1007/s00198-017-4091-3
Postexercise muscle glycogen resynthesis in humans
Burke, Louise, Van Loon, Luc and Hawley, John. (2017) Postexercise muscle glycogen resynthesis in humans. Journal of Applied Physiology. 122(5), pp. 1055 - 1067. https://doi.org/10.1152/japplphysiol.00860.2016
Consideration of insects as a source of dietary protein for human consumption
Churchward-Venne, T. A., Pinckaers, Philippe J. M., van Loon, Joop J. A. and Van Loon, Luc. (2017) Consideration of insects as a source of dietary protein for human consumption. Nutrition Reviews. 75(12), pp. 1035 - 1045. https://doi.org/10.1093/nutrit/nux057
Management of aromatase inhibitor-associated bone loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG
Hadji, P., Aapro, Matti S., Body, Jean J., Gnant, Michael, Brandi, Maria L., Reginster, Jean Y., Zillikens, M. C., Glüer, C. C., de Villiers, T., Baber, Rod, Roodman, G. David, Cooper, Cyrus, Langdahl, Bente Lomholt, Palacios, Santiago, Kanis, John, Al-Daghri, Nasser M., Nogues, Xavier, Eriksen, Erik F., Kurth, Andreas, ... Coleman, Robert E.. (2017) Management of aromatase inhibitor-associated bone loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG. Journal of Bone Oncology. 7, pp. 1 - 12. https://doi.org/10.1016/j.jbo.2017.03.001
Protein supplementation augments muscle fiber hypertrophy but does not modulate satellite cell content during prolonged resistance-type exercise training in frail elderly
Dirks, Marlou L., Tieland, Michael, Verdijk, Lex B., Losen, Mario, Nilwik, Rachel, Mensink, Marco, de Groot, Lisette C.P.G.M. and Van Loon, Luc. (2017) Protein supplementation augments muscle fiber hypertrophy but does not modulate satellite cell content during prolonged resistance-type exercise training in frail elderly. Journal of the American Medical Directors Association (JAMDA): long-term care: management, applied research and clinical issues. 18(7), pp. 608 - 615. https://doi.org/10.1016/j.jamda.2017.02.006
Glucose plus fructose ingestion for post exercise recovery greater than the sum of its parts?
Gonzalez, Javier T., Fuchs, Cas J., Betts, James A. and Van Loon, Luc. (2017) Glucose plus fructose ingestion for post exercise recovery greater than the sum of its parts? Nutrients. 9(4), pp. 1 - 15. https://doi.org/10.3390/nu9040344
Imminent risk of fracture after fracture
Johansson, Helena, Siggeirsdottir, Kristin, Harvey, Nicholas C., Oden, Anders, Gudnason, Vilmundur, McCloskey, Eugene, Sigurdsson, Gunnar and Kanis, John. (2017) Imminent risk of fracture after fracture. Osteoporosis International. 28(3), pp. 775 - 780. https://doi.org/10.1007/s00198-016-3868-0
Clinical settings in knee osteoarthritis: Pathophysiology guides treatment
Herrero-Beaumont, Gabriel, Roman-Blas, Jorge A., Bruyère, Olivier, Cooper, Cyrus, Kanis, John, Maggi, S., Rizzoli, René and Reginster, Jean-Yves. (2017) Clinical settings in knee osteoarthritis: Pathophysiology guides treatment. Maturitas. 96, pp. 54 - 57. https://doi.org/10.1016/j.maturitas.2016.11.013
Twenty-four-hour biological variation profiles of cardiac troponin I in individuals with or without chronic kidney disease
Van Der Linden, Noreen, Hilderink, Judith M., Cornelis, Tom, Kimenai, Dorien M., Klinkenberg, Lieke J.J., Van Doorn, William P., Litjens, Elisabeth J.R., Van Suijlen, Jeroen D.E., Van Loon, Luc, Bekers, Otto, Kooman, Jeroen P. and Meex, Steven J.R.. (2017) Twenty-four-hour biological variation profiles of cardiac troponin I in individuals with or without chronic kidney disease. Clinical Chemistry (Washington, DC): international journal of molecular diagnostics and laboratory medicine. 63(10), pp. 1655 - 1656. https://doi.org/10.1373/clinchem.2017.275107
Clinical usefulness of bone turnover marker concentrations in osteoporosis
Morris, H. A., Eastell, R., Jorgesen, N. R., Cavalier, E., Vasikaran, S., Chubb, S. A. P., Kanis, J. A., Cooper, C. and Makris, K.. (2017) Clinical usefulness of bone turnover marker concentrations in osteoporosis. Clinica Chimica Acta. 467, pp. 34 - 41. https://doi.org/10.1016/j.cca.2016.06.036
Dietary protein intake and distribution patterns of well-trained Dutch athletes
Gillen, Jenna B., Trommelen, Jorn, Wardenaar, Floris C., Brinkmans, Naomi Y.J., Versteegen, Joline J., Jonvik, Kristin L., Kapp, Christoph, de Vries, Jeanne, van den Borne, Joost J.G.C., Gibala, M. J. and Van Loon, Luc. (2017) Dietary protein intake and distribution patterns of well-trained Dutch athletes. International Journal of Sport Nutrition and Exercise Metabolism. 27(2), pp. 105 - 114. https://doi.org/10.1123/ijsnem.2016-0154
Epidemiology of hip fracture and the development of FRAX in Ukraine
Povoroznyuk, V. V., Grygorieva, N. V., Kanis, John, McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Korzh, M. O., Strafun, S. S., Vaida, V. M., Klymovytsky, F. V., Vlasenko, R. R. and Forosenko, V. S.. (2017) Epidemiology of hip fracture and the development of FRAX in Ukraine. Archives of Osteoporosis. 12(1), pp. 1 - 6. https://doi.org/10.1007/s11657-017-0343-2
Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice
Dijk, Francina J., van Dijk, Miriam, Walrand, Stéphane, Van Loon, Luc, van Norren, Klaske and Luiking, Yvette C.. (2017) Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice. Clinical Nutrition ESPEN. 24, pp. 127 - 133. https://doi.org/doi.org/10.1016/j.clnesp.2017.12.013
Extensive type ii muscle fiber atrophy in elderly female hip fracture patients
Kramer, Irene F., Snijders, Tim, Smeets, Joey S.J., Leenders, Marika, van Kranenburg, Janneau, den Hoed, Marcel, Verdijk, Lex B., Poeze, Martijn and Van Loon, Luc. (2017) Extensive type ii muscle fiber atrophy in elderly female hip fracture patients. Journal of Gerontology Series A: Biological Sciences and Medical Sciences. 72(10), pp. 1369 - 1375. https://doi.org/10.1093/gerona/glw253
FRAX- vs. T-score-based intervention thresholds for osteoporosis
Johansson, Helena, Azizieh, F., al Ali, N., Alessa, T., Harvey, Nicholas C., McCloskey, Eugene and Kanis, John A.. (2017) FRAX- vs. T-score-based intervention thresholds for osteoporosis. Osteoporosis International. 28(11), pp. 3099 - 3105. https://doi.org/10.1007/s00198-017-4160-7
Association of mental disorders and related medication use with risk for major osteoporotic fractures
Bolton, James M., Morin, Suzanne N., Majumdar, S. R., Sareen, Jitender, Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John and Leslie, William. (2017) Association of mental disorders and related medication use with risk for major osteoporotic fractures. JAMA Psychiatry. 74(6), pp. 641 - 648. https://doi.org/10.1001/jamapsychiatry.2017.0449
Fructose and sucrose intake increase exogenous carbohydrate oxidation during exercise
Trommelen, Jorn, Fuchs, Cas J., Beelen, M, Lenaerts, Kaatje, Jeukendrup, A. E., Cermak, N. and Van Loon, Luc. (2017) Fructose and sucrose intake increase exogenous carbohydrate oxidation during exercise. Nutrients. 9(2), pp. 1 - 12. https://doi.org/10.3390/nu9020167
The effect of abaloparatide-SC on fracture risk is independent of baseline FRAX fracture probability: a post hoc analysis of the ACTIVE study
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Harvey, Nicholas C., Jiang, Hai, Modin, Sara, Fitzpatrick, Lorraine and Kanis, John. (2017) The effect of abaloparatide-SC on fracture risk is independent of baseline FRAX fracture probability: a post hoc analysis of the ACTIVE study. Journal of Bone and Mineral Research. 32(8), pp. 1625 - 1631. https://doi.org/10.1002/jbmr.3163
Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial
Kouw, Imre W.K., Holwerda, Andrew M., Trommelen, Jorn, Kramer, Irene Fleur, Bastiaanse, Jacqueline, Halson, Shona, Wodzig, Will K.W.H., Verdijk, Lex B. and Van Loon, Luc. (2017) Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial. The Journal of Nutrition. 147(12), pp. 2252 - 2261. https://doi.org/10.3945/jn.117.254532
Erratum to: identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting
Kanis, John, Cooper, Cyrus, Rizzoli, Rene, Abrahamsen, Bo, Al-Daghri, N. M., Brandi, Maria L., Cannata, J. B., Cortet, B., Dimai, Hans P., Ferrari, S., Hadji, P., Harvey, Nicholas C., Kraenzlin, M., Kurth, Andreas, McCloskey, Eugene, Minisola, Salvatore, Thomas, T. and Reginster, Jean Y.. (2017) Erratum to: identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting. Osteoporosis International. 28(11), pp. 3285 - 3286. https://doi.org/10.1007/s00198-017-4161-6
Sodium nitrate ingestion increases skeletal muscle nitrate content in humans
Nyakayiru, Jean, Kouw, Imre W.K., Cermak, N, Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017) Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. Journal of Applied Physiology. 123(3), pp. 637 - 644. https://doi.org/10.1152/japplphysiol.01036.2016
Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men
Tsintzas, Kostas, Stephens, F. B., Snijders, Tim, Wall, Benjamin T., Cooper, Scott, Mallinson, Joanne, Verdijk, Lex B. and Van Loon, Luc. (2017) Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men. Experimental Gerontology. 93, pp. 36 - 45. https://doi.org/10.1016/j.exger.2017.03.018
Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review
Beaudart, Charlotte, Dawson, A., Shaw, S. C., Harvey, Nicholas C., Kanis, John, Binkley, Neil, Reginster, Jean Yves, Chapurlat, R., Chan, D. C., Bruyère, O., Rizzoli, Rene, Cooper, Cyrus and Dennison, Elaine M.. (2017) Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review. Osteoporosis International. 28(6), pp. 1817 - 1833. https://doi.org/10.1007/s00198-017-3980-9
FRAX update
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, Leslie, William D. and McCloskey, Eugene V.. (2017) FRAX update. Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health. 20(3), pp. 360 - 367. https://doi.org/10.1016/j.jocd.2017.06.022
Commentaries on Viewpoint: A time for exercise: the exercise window
Boule, Normand G., Terada, Tasuku, Francois, Monique E., Hawley, John, Cotter, James D., Kruse, Nicholas T., McDonald, Matthew W., Olver, T D., Paoli, Antonio, Sacchetti, Massimo, Di Luigi, Luigi, van Dijk, Jan W., Van Loon, Luc, Yardley, Jane E., DiPietro, Loretta, Gribok, Andrei and Rumpler, William. (2017) Commentaries on Viewpoint: A time for exercise: the exercise window. Journal of Applied Physiology. 122(1), pp. 210 - 213. https://doi.org/10.1152/japplphysiol.00938.2016
No effect of acute and 6-day nitrate supplementation on VO2 and time-trial performance in highly trained cyclists
Nyakayiru, Jean, Jonvik, Kristin L., Pinckaers, Philippe J.M., Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017) No effect of acute and 6-day nitrate supplementation on VO2 and time-trial performance in highly trained cyclists. International Journal of Sport Nutrition and Exercise Metabolism. 27(1), pp. 11 - 17. https://doi.org/10.1123/ijsnem.2016-0034
Evaluation of clinical risk factors for osteoporosis and applicability of the FRAX tool in Joinville City, southern Brazil
Silva, Dalisbor M.W., Borba, Victoria Z.C. and Kanis, John. (2017) Evaluation of clinical risk factors for osteoporosis and applicability of the FRAX tool in Joinville City, southern Brazil. Archives of Osteoporosis. 12(111), pp. 1 - 8. https://doi.org/10.1007/s11657-017-0405-5
Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position
Holwerda, Andrew M., Lenaerts, Kaatje, Bierau, Jörgen, Wodzig, Will K.W.H. and Van Loon, Luc. (2017) Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position. Applied Physiology, Nutrition and Metabolism. 42(7), pp. 738 - 743. https://doi.org/10.1139/apnm-2016-0522
The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF)
Harvey, Nicholas C., Biver, Emmanuel, Kaufman, J,, Bauer, Jürgen M., Branco, J., Brandi, Maria Luisa, Bruyère, O., Coxam, V., Cruz-Jentoft, Alfonso J., Czerwinski, E., Dimai, Hans P., Fardellone, P., Landi, Francesco, Reginster, Jean Yves, Dawson-Hughes, Bess, Kanis, John, Rizzoli, Rene and Cooper, Cyrus. (2017) The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF). Osteoporosis International. 28(2), pp. 447 - 462. https://doi.org/10.1007/s00198-016-3773-6
UK clinical guideline for the prevention and treatment of osteoporosis
Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Gittoes, Neil, Gregson, C., Harvey, Nicholas C., Hope, S., Kanis, John, McCloskey, Eugene, Poole, Kenneth E.S., Reid, David M., Selby, P., Thompson, F., Thurston, A. and Vine, N.. (2017) UK clinical guideline for the prevention and treatment of osteoporosis. Archives of Osteoporosis. 12(43), pp. 1 - 24. https://doi.org/10.1007/s11657-017-0324-5
Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players
Nyakayiru, Jean, Jonvik, Kristin L., Trommelen, Jorn, Pinckaers, Philippe J.M., Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017) Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players. Nutrients. 9(3), pp. 1 - 10. https://doi.org/10.3390/nu9030314
The prevention of fragility fractures in patients with non-metastatic prostate cancer: A position statement by the international osteoporosis foundation
Cianferotti, Luisella, Bertoldo, Francesco, Carini, Marco, Kanis, John A., Lapini, Alberto, Longo, Nicola, Martorana, Giuseppe, Mirone, Vincenzo, Reginster, Jean-Yves, Rizzoli, Rene and Brandi, Maria Luisa. (2017) The prevention of fragility fractures in patients with non-metastatic prostate cancer: A position statement by the international osteoporosis foundation. Oncotarget. 8(43), pp. 75646 - 75663. https://doi.org/10.18632/oncotarget.17980
FRAX-based intervention and assessment thresholds in seven Latin American countries
Clark, P., Denova-Gutiérrez, E., Zerbini, Cristiano, Sanchez, A., Messina, O. D., Jaller, J. J., Campusano, C., Orces, C. H., Riera, G., Johansson, Helena and Kanis, John. (2017) FRAX-based intervention and assessment thresholds in seven Latin American countries. Osteoporosis International. 29(3), pp. 707 - 715. https://doi.org/10.1007/s00198-017-4341-4
Seasonal variation in vitamin d status in elite athletes: a longitudinal study
Backx, E. M.P., van der Avoort, Cindy van, Tieland, Michael, Maase, K., Kies, A. K., Van Loon, Luc, de Groot, Lisette C.P.G.M. and Mensink, M.. (2017) Seasonal variation in vitamin d status in elite athletes: a longitudinal study. International Journal of Sport Nutrition and Exercise Metabolism. 27(1), pp. 6 - 10. https://doi.org/10.1123/ijsnem.2016-0177
Glycemic control during consecutive days with prolongedwalking exercise in individuals with type 1 diabetes mellitus
van Dijk, Jan Willem, Eijsvogels, Thijs M., Nyakayiru, Jean, Schreuder, Tim H. A., Hopman, Maria T., Thijssen, Dick H. and Van Loon, Lucas. (2016) Glycemic control during consecutive days with prolongedwalking exercise in individuals with type 1 diabetes mellitus. Diabetes Research and Clinical Practice. 117, pp. 74 - 81. https://doi.org/10.1016/j.diabres.2016.04.053
May bed rest cause greater muscle loss than limb immobilization?
Dirks, Marlou L., Backx, E. M. P., Wall, Benjamin T., Verdijk, Lex B. and van Loon, Luc. (2016) May bed rest cause greater muscle loss than limb immobilization? Acta Physiologica. 218(1), pp. 10 - 12. https://doi.org/10.1111/apha.12699
Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study
Rozenberg, Robert, Mankowski, Robert T., van Loon, Luc, Langendonk, Janneke G., Sijbrands, Eric J. G., van den Meiracker, Anton H., Stam, Henk J. and Praet, Stephan F. E.. (2016) Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study. European Journal of Medical Research. 21(1), pp. 1 - 8. https://doi.org/10.1186/s40001-015-0194-5
Adjusting hip fracture probability in men and women using hip axis length: The Manitoba Bone Density Database
Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John Anthony. (2016) Adjusting hip fracture probability in men and women using hip axis length: The Manitoba Bone Density Database. Journal of Clinical Densitometry. 19(3), pp. 326 - 331. https://doi.org/10.1016/j.jocd.2015.07.004
A systematic review of intervention thresholds based on FRAX: A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation
Kanis, John A., Harvey, Nicholas C., Cooper, Cyrus, Johansson, Helena, Oden, Anders, McCloskey, Eugene V., The Advisory Board of the National Osteoporosis Guideline Group, and The Advisory Board of the National Osteoporosis Guideline Group. (2016) A systematic review of intervention thresholds based on FRAX: A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Archives of Osteoporosis. https://doi.org/10.1007/s11657-016-0278-z
FRAX predicts incident falls in elderly men: findings from MrOs Sweden
Harvey, Nicholas C., Johansson, Helena, Oden, Anders, Karlsson, Magnus, Rosengren, Björn E., Ljunggren, Östen, Cooper, Cyrus, McCloskey, Eugene V., Kanis, John A., Ohlsson, C. and Mellström, Dan. (2016) FRAX predicts incident falls in elderly men: findings from MrOs Sweden. Osteoporosis International. 27(1), pp. 267 - 274. https://doi.org/10.1007/s00198-015-3295-7
Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey
Bruyère, O., Beaudart, Charlotte, Reginster, Jean Yves, Buckinx, F., Schoene, D., Hirani, V., Cooper, Cyrus, Kanis, John, Rizzoli, Rene, McCloskey, Eugene, Cederholm, T., Cruz-Jentoft, Alfonso J. and Freiberger, E.. (2016) Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey. European Geriatric Medicine. 7(3), pp. 243 - 246. https://doi.org/10.1016/j.eurger.2015.12.009
Cardiac Troponin T and i Release after a 30-km Run
Klinkenberg, Lieke J. J., Luyten, Peter, Van Der Linden, Noreen, Urgel, Kim, Snijders, Daniëlle P. C., Knackstedt, Christian, Dennert, Robert, Kietselaer, Bastiaan L. J. H., Mingels, Alma M. A., Cardinaels, Eline P. M., Peeters, Frederique E. C. M., Van Suijlen, Jeroen D. E., Kate, Joop Ten, Marsch, Elke, Theelen, Thomas L., Sluimer, Judith C., Wouters, Kristiaan, Bekers, Otto, Bekkers, Sebastiaan C. A. M., ... Meex, Steven J. R.. (2016) Cardiac Troponin T and i Release after a 30-km Run. American Journal of Cardiology. 118(2), pp. 281 - 287. https://doi.org/10.1016/j.amjcard.2016.04.030
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, Nathalie, Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, Rene, Cortet, Bernard, Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., Strandberg, Timo, Alvarez, M. N., ... Treml, J.. (2016) A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. European Geriatric Medicine. 7(6), pp. 519 - 525. https://doi.org/10.1016/j.eurger.2016.04.012
Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population
van der Linden, Noreen, Klinkenberg, Lieke J. J., Bekers, Otto, van Loon, Luc, Van Dieijen-Visser, Marja P., Zeegers, Maurice P. and Meex, Steven J. R.. (2016) Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population. Medicine. https://doi.org/10.1097/MD.0000000000005703
Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion
Wall, Benjamin T., Dirks, Marlou L., Snijders, Tim, Willem van Dijk, Jan, Fritsch, Mario, Verdijk, Lex B. and Van Loon, Luc. (2016) Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion. American Journal of Physiology - Endocrinology and Metabolism. https://doi.org/10.1152/ajpendo.00227.2015
Direct comparison of FRAX(R) and a simplified fracture risk assessment tool in routine clinical practice: A registry-based cohort study
Leslie, William D., Majumdar, S. R., Lix, Lisa M., Josse, R. G., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2016) Direct comparison of FRAX(R) and a simplified fracture risk assessment tool in routine clinical practice: A registry-based cohort study. Osteoporosis International. 27(9), pp. 2689 - 2695. https://doi.org/10.1007/s00198-016-3613-8
A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, Nathalie, Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John, Reginster, Jean Y., Rizzoli, Rene, Cortet, B., Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., Strandberg, Timo E., Alvarez, M. N., ... Macijauskien, J. (2016) A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clinical and Experimental Research. 28(4), pp. 797 - 803. https://doi.org/10.1007/s40520-016-0588-4
FRAX updates 2016
McCloskey, Eugene V., Harvey, Nicholas C., Johansson, Helena and Kanis, John A.. (2016) FRAX updates 2016. Current Opinion in Rheumatology. 28(4), pp. 433 - 441. https://doi.org/10.1097/BOR.0000000000000304
Diacerein: Benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO
Pavelka, Karel, Bruyère, Olivier, Cooper, Cyrus, Kanis, John A., Leeb, Burkhard F., Maheu, Emmanuel, Martel-Pelletier, Johanne, Monfort, Jordi, Pelletier, Jean-Pierre, Rizzoli, Rene and Reginster, Jean-Yves. (2016) Diacerein: Benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO. Drugs and Aging. 33(2), pp. 75 - 85. https://doi.org/10.1007/s40266-016-0347-4
Impact of diet composition on blood glucose regulation
Russell, Wendy R., Baka, Athanasia, Bjorck, Inger, Delzenne, Nathalie, Gao, Dan, Griffiths, Helen R., Hadjilucas, Ellie, Juvonen, Kristiina, Lahtinen, Sampo, Lansink, Mirian, van Loon, Luc, Mykkanen, Hannu, Ostman, Elin, Riccardi, Gabrielle, Vinoy, Sophie and Weickert, Martin O.. (2016) Impact of diet composition on blood glucose regulation. Critical Reviews in Food Science and Nutrition. 56(4), pp. 541 - 590. https://doi.org/10.1080/10408398.2013.792772
The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient
Sipers, Walther M. W. H., Verdijk, Lex B., Sipers, Simone J. E., Schols, Jos M. G. A. and Van Loon, Luc. (2016) The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient. Journal of the American Medical Directors Association. 17(5), pp. 1 - 7. https://doi.org/10.1016/j.jamda.2016.02.026
Quality of life, resource use, and costs related to hip fracture in Estonia
Jurisson, Mikk, Pisarev, Heti, Kanis, John, Borgstrom, F., Svedbom, A., Kallikorm, R., Lember, M. and Uusküla, A.. (2016) Quality of life, resource use, and costs related to hip fracture in Estonia. Osteoporosis International. 27(8), pp. 2555 - 2566. https://doi.org/10.1007/s00198-016-3544-4
Resistance training increases skeletal muscle capillarization in healthy older men
Verdijk, Lex B., Snijders, Tim, Holloway, Tanya M., Van Kranenburg, Janneau and van Loon, Luc. (2016) Resistance training increases skeletal muscle capillarization in healthy older men. Medicine and Science in Sports and Exercise. 48(11), pp. 2157 - 2164. https://doi.org/10.1249/MSS.0000000000001019
Habitual Dietary Nitrate Intake in Highly Trained Athletes
Jonvik, Kristin L., Nyakayiru, Jean, Willem van Dijk, Jan, Wardenaar, Floris C., Van Loon, Lucas and Verdijk, Lex B.. (2016) Habitual Dietary Nitrate Intake in Highly Trained Athletes. International Journal of Sport Nutrition and Exercise Metabolism. https://doi.org/10.1123/ijsnem.2016-0239
Protein intake and lean body mass preservation during energy intake restriction in overweight older adults
Backx, E. M. P., Tieland, Michael, Borgonjen-Van Den Berg, Karin J., Claessen, P. R., Van Loon, Lucas and de Groot, Lisette C.P.G.M.. (2016) Protein intake and lean body mass preservation during energy intake restriction in overweight older adults. International Journal of Obesity. https://doi.org/10.1038/ijo.2015.182
Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training
Snijders, Tim, Smeets, Joey S. J., Van Kranenburg, Janneau, Kies, A. K., Van Loon, Lucas and Verdijk, Lex B.. (2016) Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training. Acta Physiologica. https://doi.org/10.1111/apha.12609
Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning
Wall, Benjamin T., Burd, Nicholas A., Franssen, Rinske, Gorissen, Stefan H. M., Snijders, Tim, Senden, Joan M., Gijsen, Annemie P. and van Loon, Luc. (2016) Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning. American Journal of Physiology - Endocrinology and Metabolism. 311(6), pp. 964 - 973. https://doi.org/10.1152/ajpendo.00325.2016
Longer duration of diabetes strongly impacts fracture risk assessment: The Manitoba BMD cohort
Majumdar, Sumit R., Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2016) Longer duration of diabetes strongly impacts fracture risk assessment: The Manitoba BMD cohort. Journal of Clinical Endocrinology and Metabolism. 101(11), pp. 4489 - 4496. https://doi.org/10.1210/jc.2016-2569
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K. E., Vellas, B., Maggi, S. and Strandberg, T.. (2016) A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. Aging Clinical and Experimental Research. 28(4), pp. 797 - 803. https://doi.org/10.1007/s40520-016-0588-4
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K. E., Vellas, B., Maggi, S. and Strandberg, T.. (2016) A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. Journal of Nutrition, Health and Aging. 20(6), pp. 647 - 652. https://doi.org/10.1007/s12603-016-0741-y
Cost-effectiveness of intervention thresholds for the treatment of osteoporosis based on FRAX(R) in Portugal
Marques, Andréa, Lourenço, Óscar, Ortsäter, Gustaf, Borgstrom, Fredrik, Kanis, John A. and da Silva, José António P.. (2016) Cost-effectiveness of intervention thresholds for the treatment of osteoporosis based on FRAX(R) in Portugal. Calcified Tissue International. 99(2), pp. 131 - 141. https://doi.org/10.1007/s00223-016-0132-8
May bed rest cause greater muscle loss than limb immobilization?
Dirks, Marlou L., Backx, E. M. P., Wall, Benjamin T., Verdijk, Lex B. and Van Loon, Lucas. (2016) May bed rest cause greater muscle loss than limb immobilization? Acta Physiologica. 218(1), pp. 10 - 12. https://doi.org/10.1111/apha.12699
Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture
Ferrari, S., Reginster, Jean Yves, Brandi, Maria Luisa, Kanis, John A., Devogelaer, J. P., Kaufman, J. M., Féron, J. M., Kurth, Andreas and Rizzoli, René. (2016) Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture. Archives of Osteoporosis. 11(1), pp. 1 - 12. https://doi.org/10.1007/s11657-016-0292-1
Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and O
Cooper, Cyrus, Bardin, Thomas, Brandi, M. L., Cacoub, Patrice, Caminis, John, Civitelli, Roberto, Cutolo, Maurizio, Dere, Willard, Devogelaer, Jean-Pierre, Diez-Perez, Adolfo, Einhorn, Thomas A., Emonts, Patrick, Ethgen, Olivier, Kanis, John A., Kaufman, Jean-Marc, Kvien, Tore K., Lems, Willem F., McCloskey, Eugene, Miossec, Pierre, ... Reginster, Jean-Yves. (2016) Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and O. Aging Clinical and Experimental Research. 28(1), pp. 1 - 16. https://doi.org/10.1007/s40520-015-0522-1
SIGN Guidelines for Scotland: BMD Versus FRAX Versus QFracture
Kanis, John A., Compston, Juliet, Cooper, Cyrus, Harvey, Nicholas C., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2016) SIGN Guidelines for Scotland: BMD Versus FRAX Versus QFracture. Calcified Tissue International. 98(5), pp. 417 - 425. https://doi.org/10.1007/s00223-015-0092-4
A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting
Bruyère, Olivier, Cooper, Cyrus, Pelletier, Jean-Pierre, Maheu, Emmanuel, Rannou, François, Branco, Jaime, Brandi, Maria Luisa, Kanis, John A., Altman, Roy D., Hochberg, Marc C., Martel-Pelletier, Johanne and Reginster, Jean-Yves. (2016) A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting. Seminars in Arthritis and Rheumatism. 45(4), pp. S3 - S11. https://doi.org/10.1016/j.semarthrit.2015.11.010
Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction
Klinkenberg, Lieke J. J., Wildi, Karin, Van Der Linden, Noreen, Kouw, Imre W. K., Niens, Marijke, Twerenbold, Raphael, Gimenez, Maria Rubini, Puelacher, Christian, Neuhaus, Jean Daniel, Hillinger, Petra, Nestelberger, Thomas, Boeddinghaus, Jasper, Grimm, Karin, Sabti, Zaid, Bons, Judith A. P., Van Suijlen, Jeroen D. E., Tan, Frans E. S., Kate, Joop Ten, Bekers, Otto, ... Meex, Steven J. R.. (2016) Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction. Clinical Chemistry. 62(12), pp. 1602 - 1611. https://doi.org/10.1373/clinchem.2016.257485
A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX
McCloskey, Eugene, Oden, Anders, Harvey, Nicholas C., Leslie, William, Hans, D., Johansson, Helena, Barkmann, Reinhard, Boutroy, Stephanie, Brown, J. P., Chapurlat, Roland D., Elders, Petra J. M., Fujita, Yuki, Glüer, Claus C., Goltzman, David, Iki, Masayuki, Karlsson, M. K., Kindmark, Andreas, Kotowicz, Mark, Kurumatani, Norio, ... Kanis, John A.. (2016) A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX. Journal of Bone and Mineral Research. 31(5), pp. 940 - 948. https://doi.org/10.1002/jbmr.2734
Sarcopenia in daily practice: Assessment and management
Beaudart, Charlotte, McCloskey, Eugene, Bruyère, Olivier, Cesari, Matteo, Rolland, Yves, Rizzoli, Rene, de Carvalho, Islène Araujo, Thiyagarajan, Jotheeswaran Amuthavalli, Bautmans, Ivan, Bertière, Marie-Claude, Brandi, Maria Luisa, Al-Daghri, Nasser M., Burlet, Nansa, Cavalier, Etienne, Cerreta, Francesca, Cherubini, Antonio, Fielding, Roger, Gielen, Evelien, Landi, Francesco, ... Cooper, Cyrus. (2016) Sarcopenia in daily practice: Assessment and management. BMC Geriatrics. 16(170), pp. 1 - 10. https://doi.org/10.1186/s12877-016-0349-4
Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness
Hangelbroek, Roland W. J., Fazelzadeh, Parastoo, Tieland, Michael, Boekschoten, Mark V., Hooiveld, Guido J. E. J., van Duynhoven, John P. M., Timmons, James A., Verdijk, Lex B., de Groot, Lisette C. P. G. M., Van Loon, Luc and Müller, Michael. (2016) Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness. Journal Cachexia Sarcopenia Muscle. 7(5), pp. 604 - 614. https://doi.org/10.1002/jcsm.12099
The impact of 1-year vitamin D supplementation on vitamin D status in athletes: A dose-response study
Backx, E. M. P., Tieland, Michael, Maase, K., Kies, A. K., Mensink, M., Van Loon, Luc and de Groot, Lisette C. P. G. M.. (2016) The impact of 1-year vitamin D supplementation on vitamin D status in athletes: A dose-response study. European Journal of Clinical Nutrition. 70(9), pp. 1009 - 1014. https://doi.org/10.1038/ejcn.2016.133
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990--2015: a systematic analysis for the Global Burden of Disease Study 2015
Vos, Theo, Allen, Christine, Arora, Megha, Barber, Ryan M., Bhutta, Zulfiqar A., Brown, Alexandria, Carter, Austin, Casey, Daniel C., Charlson, Fiona J., Chen, Alan Z., Coggeshall, Megan, Cornaby, Leslie, Dandona, Lalit, Dicker, Daniel J., Dilegge, Tina, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Tom, ... Murray, Christopher J. L.. (2016) Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990--2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1545 - 1602. https://doi.org/10.1016/S0140-6736(16)31678-6
Can we treat to target in osteoporosis?
McCloskey, Eugene, Harvey, Nicholas C. and Kanis, John. (2015) Can we treat to target in osteoporosis? International Journal of Clinical Rheumatology. 10(1), pp. 1 - 4. https://doi.org/10.2217/ijr.14.59
Burden of high fracture probability worldwide: Secular increases 2010--2040
Oden, Anders, McCloskey, Eugene V., Kanis, John A., Harvey, Nicholas C. and Johansson, Helena. (2015) Burden of high fracture probability worldwide: Secular increases 2010--2040. Osteoporosis International. 26(9), pp. 2243 - 2248. https://doi.org/10.1007/s00198-015-3154-6
Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis
Reginster, Jean Yves, Cooper, Cyrus, Hochberg, Marc, Pelletier, Jean Pierre, Rizzoli, R, Kanis, John A., Abadie, Eric, Maheu, E., Brandi, Maria Luisa, Devogelaer, J. P., Branco, J., Herrero-Beaumont, G., D'Hooghe, Pieter and Bruyère, O.. (2015) Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis. Current Medical Research and Opinion. 31(5), pp. 1041 - 1045. https://doi.org/10.1185/03007995.2015.1027183
Intervention thresholds and the diagnosis of osteoporosis
Kanis, John A., McCloskey, Eugene, Harvey, Nicholas C., Johansson, Helena and Leslie, William D.. (2015) Intervention thresholds and the diagnosis of osteoporosis. Journal of Bone and Mineral Research. 30(10), pp. 1747 - 1753. https://doi.org/10.1002/jbmr.2531
Hypoxia induces a prothrombotic state independently of the physical activity
Ninivaggi, Marisa, De Laat, Marieke, Lancé, Marcus M. D., Kicken, Cécile H., Pelkmans, Leonie, Bloemen, Saartje, Dirks, Marlou L., Van Loon, Luc, Govers-Riemslag, José W. P., Lindhout, Theo, Konings, Joke and De Laat, Bas. (2015) Hypoxia induces a prothrombotic state independently of the physical activity. PLoS ONE. 10(10), pp. 1 - 14. https://doi.org/10.1371/journal.pone.0141797
Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool
Javaid, M. K., Kyer, C., Mitchell, P. J., Chana, J., Moss, C., Edwards, M. H., McLellan, A. R., Stenmark, J., Pierroz, D. D., Schneider, M. C., Kanis, John A., Akesson, K. and Cooper, Cyrus. (2015) Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool. Osteoporosis International. 26(11), pp. 2573 - 2578. https://doi.org/10.1007/s00198-015-3192-0
Health economic aspects of vertebral augmentation procedures
Borgström, F., Beall, D. P., Berven, S., Boonen, S., Christie, S., Kallmes, D. F., Kanis, John A., Olafsson, G., Singer, A. J. and Åkesson, K.. (2015) Health economic aspects of vertebral augmentation procedures. Osteoporosis International. 26(4), pp. 1239 - 1249. https://doi.org/10.1007/s00198-014-2953-5
Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice
Harvey, N. C., Glüer, C. C., Binkley, N., McCloskey, E. V., Brandi, M. L., Cooper, C., Kendler, D., Lamy, O., Laslop, A., Camargos, B. M., Reginster, J-Y, Rizzoli, R. and Kanis, J. A.. (2015) Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice. Bone. 78, pp. 216 - 224. https://doi.org/10.1016/j.bone.2015.05.016
Adjusting fracture probability by trabecular bone score
McCloskey, Eugene V., Oden, Anders, Harvey, Nicholas C., Leslie, William D., Hans, Didier, Johansson, Helena and Kanis, John A.. (2015) Adjusting fracture probability by trabecular bone score. Calcified Tissue International. 96(6), pp. 500 - 509. https://doi.org/10.1007/s00223-015-9980-x
Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty
Arden, Nigel, Richette, Pascal, Cooper, Cyrus, Bruyère, Olivier, Abadie, Eric, Branco, Jaime, Brandi, Maria Luisa, Berenbaum, Francis, Clerc, Cécile, Dennison, Elaine M., Devogelaer, Jean-Pierre, Hochberg, Marc, D'Hooghe, Pieter, Herrero-Beaumont, Gabriel, Kanis, John A., Laslop, Andrea, Leblanc, Véronique, Maggi, Stefania, Mautone, Giuseppe, ... Reginster, Jean-Yves. (2015) Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty. Drugs and Aging. 32(7), pp. 525 - 535. https://doi.org/10.1007/s40266-015-0276-7
Incidence of hip fracture in Brazil and the development of a FRAX model
Zerbini, C. A. F., Szejnfeld, V. L., Abergaria, B. H., McCloskey, Eugene V., Johansson, Helena and Kanis, John A.. (2015) Incidence of hip fracture in Brazil and the development of a FRAX model. Archives of Osteoporosis. 10(1), pp. 1 - 7. https://doi.org/10.1007/s11657-015-0224-5
A systematic review of cost-effectiveness analyses of drugs for postmenopausal osteoporosis
Hiligsmann, Mickaël, Evers, Silvia M., Sedrine, Wafa Ben, Kanis, John A., Ramaekers, Bram, Reginster, Jean Yves, Silverman, S., Wyers, Caroline E. and Boonen, Annelies. (2015) A systematic review of cost-effectiveness analyses of drugs for postmenopausal osteoporosis. PharmacoEconomics. 33(3), pp. 205 - 224. https://doi.org/10.1007/s40273-014-0231-1
Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: Expert consensus statement
Reginster, Jean Yves, Reiter-Niesert, S., Bruyère, O., Berenbaum, F., Brandi, Maria-Luisa, Branco, J., Devogelaer, J.-P., Herrero-Beaumont, G., Kanis, John A., Maggi, S., Maheu, E., Richette, P., Rizzoli, R. and Cooper, C.. (2015) Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: Expert consensus statement. Osteoarthritis and Cartilage. 23(12), pp. 2086 - 2093. https://doi.org/10.1016/j.joca.2015.07.001
Predictive ability of heel quantitative ultrasound for incident fractures: an individual-level meta-analysis
McCloskey, Eugene V., Kanis, John A., Oden, Anders, Harvey, Nicholas C., Bauer, D., Gonzalez-Macias, J., Hans, D., Kaptoge, S., Krieg, Marc Antoine, Kwok, T., Marin, F., Moayyeri, A., Orwoll, E., Gluёr, C. and Johansson, Helena. (2015) Predictive ability of heel quantitative ultrasound for incident fractures: an individual-level meta-analysis. Osteoporosis International. 26(7), pp. 1979 - 1987. https://doi.org/10.1007/s00198-015-3072-7
Prolonged adaptation to a low or high protein diet does not modulate basal muscle protein synthesis rates: A substudy
Hursel, Rick, Martens, Eveline A. P., Gonnissen, Hanne K. J., Hamer, Henrike M., Senden, Joan M., Van Loon, Luc and Westerterp-Plantenga, Margriet S.. (2015) Prolonged adaptation to a low or high protein diet does not modulate basal muscle protein synthesis rates: A substudy. PLoS ONE. 10(9), pp. 1 - 15. https://doi.org/10.1371/journal.pone.0137183
FRAX-based assessment and intervention thresholds - An exploration of thresholds in women aged 50 years and older in the UK
McCloskey, Eugene V., Kanis, John A., Johansson, Helena, Harvey, Nicholas C., Oden, Anders, Cooper, Alun, Cooper, C., Francis, Roger M., Reid, D. M., Marsh, D., Selby, P., Thompson, F., Hewitt, S. and Compston, Juliet E.. (2015) FRAX-based assessment and intervention thresholds - An exploration of thresholds in women aged 50 years and older in the UK. Osteoporosis International. 26(8), pp. 2091 - 2099. https://doi.org/10.1007/s00198-015-3176-0
FRAX and the effect of teriparatide on vertebral and non-vertebral fracture
Harvey, Nicholas C., Kanis, John A., Oden, Anders, Burge, R., Mitlak, B., Johansson, Helena and McCloskey, Eugene V.. (2015) FRAX and the effect of teriparatide on vertebral and non-vertebral fracture. Osteoporosis International. 26(11), pp. 2677 - 2684. https://doi.org/10.1007/s00198-015-3173-3
Can elite athletes benefit from dietary nitrate supplementation?
Jonvik, Kristin L., Nyakayiru, Jean, Van Loon, Luc and Verdijk, Lex B.. (2015) Can elite athletes benefit from dietary nitrate supplementation? Journal of Applied Physiology. 119(6), pp. 759 - 761. https://doi.org/10.1152/japplphysiol.00232.2015
Exercise strategies to optimize glycemic control in type 2 diabetes: A continuing glucose monitoring perspective
van Dijk, Jan Willem and Van Loon, Luc. (2015) Exercise strategies to optimize glycemic control in type 2 diabetes: A continuing glucose monitoring perspective. Diabetes Spectrum. 28(1), pp. 24 - 31. https://doi.org/10.2337/diaspect.28.1.24
Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion
Wall, Benjamin T., Gorissen, Stefan H. M., Pennings, Bart, Koopman, René, Groen, Bart B. L., Verdijk, Lex B. and Van Loon, Luc. (2015) Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion. PLoS ONE. 10(11), pp. 1 - 13. https://doi.org/10.1371/journal.pone.0140903
The clinical use of vitamin D metabolites and their potential developments: A position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
Cianferotti, Luisella, Cricelli, Claudio, Kanis, John A., Nuti, Ranuccio, Reginster, Jean-Yves, Ringe, Johann D., Rizzoli, Rene and Brandi, Maria Luisa. (2015) The clinical use of vitamin D metabolites and their potential developments: A position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Endocrine. 50(1), pp. 12 - 26. https://doi.org/10.1007/s12020-015-0606-x
Hip axis length is a FRAX-and bone density-independent risk factor for hip fracture in women
Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2015) Hip axis length is a FRAX-and bone density-independent risk factor for hip fracture in women. Journal of Clinical Endocrinology and Metabolism. 100(5), pp. 2063 - 2070. https://doi.org/10.1210/jc.2014-4390
Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older
Bischoff-Ferrari, Heike A., Orav, J. E., Kanis, John A., Rizzoli, R., Schlögl, M., Staehelin, H. B., Willett, Walter C. and Dawson-Hughes, B.. (2015) Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Osteoporosis International. 26(12), pp. 2793 - 2802. https://doi.org/10.1007/s00198-015-3194-y
Is the Swedish FRAX model appropriate for Swedish immigrants?
Johansson, Helena, Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene V., Kanis, John A., Harvey, Nicholas C., Karlsson, M. K. and Mellström, Dan. (2015) Is the Swedish FRAX model appropriate for Swedish immigrants? Osteoporosis International. 26(11), pp. 2617 - 2622. https://doi.org/10.1007/s00198-015-3180-4
Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, Olivier, Cooper, Cyrus, Arden, Nigel, Branco, Jaime, Brandi, Maria Luisa, Herrero-Beaumont, Gabriel, Berenbaum, Francis, Dennison, Elaine M., Devogelaer, Jean-Pierre, Hochberg, Marc, Kanis, John A., Laslop, Andrea, McAlindon, Tim, Reiter, Susanne, Richette, Pascal, Rizzoli, Rene and Reginster, Jean-Yves. (2015) Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis. Drugs and Aging. 32(3), pp. 179 - 187. https://doi.org/10.1007/s40266-015-0243-3
Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX
Harvey, Nicholas C., Kanis, John A., Oden, Anders, Nakamura, T., Shiraki, M., Sugimoto, T., Kuroda, T., Johansson, Helena and McCloskey, Eugene V.. (2015) Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX. Osteoporosis International. 26(9), pp. 2347 - 2353. https://doi.org/10.1007/s00198-015-3129-7
Serum 25-hydroxyvitamin D levels: Variability, knowledge gaps, and the concept of a desirable range
El-Hajj Fuleihan, Ghada, Bouillon, Roger, Clarke, Bart, Chakhtoura, Marlene, Cooper, Cyrus, McClung, Michael R. and Singh, Ravinder J.. (2015) Serum 25-hydroxyvitamin D levels: Variability, knowledge gaps, and the concept of a desirable range. Journal of Bone and Mineral Research. 30(7), pp. 1119 - 1133. https://doi.org/10.1002/jbmr.2536
FRAX and fracture prediction without bone mineral density
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Oden, Anders, Leslie, William D. and McCloskey, Eugene. (2015) FRAX and fracture prediction without bone mineral density. Climacteric. 18, pp. 2 - 9. https://doi.org/10.3109/13697137.2015.1092342
Post-prandial protein handling: You are what you just ate
Groen, Bart B. L., Horstman, Astrid M. H., Hamer, Henrike M., De Haan, Michiel, Van Kranenburg, Janneau, Bierau, Jörgen, Poeze, Martijn, Wodzig, Will K. W. H., Rasmussen, Blake B. and van Loon, Luc. (2015) Post-prandial protein handling: You are what you just ate. PLoS ONE. 10(11), pp. 1 - 22. https://doi.org/10.1371/journal.pone.0141582
Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study
Vimaleswaran, Karani S., Cavadino, Alana, Berry, Diane J., Jorde, Rolf, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J. Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, Andrew, Mangino, Massimo, Jablonski, Kathleen A., Nolte, Ilja M., Houston, Denise K., Ahluwalia, Tarunveer Singh, van der Most, Peter J., Pasko, Dorota, Zgaga, Lina, ... Hyppönen, Elina. (2014) Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study. The Lancet Diabetes & Endocrinology. 2(9), pp. 719 - 729. https://doi.org/10.1016/S2213-8587(14)70113-5
The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX
Siggeirsdottir, K., Aspelund, T., Johansson, Helena, Gudmundsson, E. F., Mogensen, B., Jonsson, B. Y., Gudnason, V., McCloskey, Eugene, Oden, Anders, Sigurdsson, G. and Kanis, John A.. (2014) The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX. Osteoporosis International. 25(10), pp. 2445 - 2451. https://doi.org/10.1007/s00198-014-2777-3
Epidemiology and economic burden of osteoporosis in Switzerland
Svedbom, A., Ivergard, M., Hernlund, E., Rizzoli, R. and Kanis, John A.. (2014) Epidemiology and economic burden of osteoporosis in Switzerland. Archives of Osteoporosis. 9, pp. 187 - 187. https://doi.org/10.1007/s11657-014-0187-y
Management of osteoporosis of the oldest old
Rizzoli, R, Branco, J., Brandi, Maria Luisa, Boonen, S., Bruyère, O., Cacoub, P., Cooper, Cyrus, Diez-Perez, A, Duder, J., Fielding, R. A., Harvey, Nicholas C., Hiligsmann, Mickaël, Kanis, John A., Petermans, J., Ringe, J. D., Tsouderos, Y., Weinman, J. and Reginster, Jean Yves. (2014) Management of osteoporosis of the oldest old. Osteoporosis International. 25(11), pp. 2507 - 2529. https://doi.org/10.1007/s00198-014-2755-9
Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures
Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2014) Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures. Osteoporosis International. 25(1), pp. 235 - 241. https://doi.org/10.1007/s00198-013-2460-0
Lumbar spine texture enhances 10-year fracture probability assessment
Leslie, William D., Johansson, Helena, Kanis, John A., Lamy, Olivier, Oden, Anders, McCloskey, Eugene V. and Hans, D.. (2014) Lumbar spine texture enhances 10-year fracture probability assessment. Osteoporosis International. 25(9), pp. 2271 - 2277. https://doi.org/10.1007/s00198-014-2761-y
Value of biomarkers in osteoarthritis: Current status and perspectives
Lotz, M., Martel-Pelletier, Johanne, Christiansen, Claus, Brandi, Maria Luisa, Bruyère, O., Chapurlat, Roland D., Collette, J., Cooper, Cyrus, Giacovelli, G., Kanis, John A., Karsdal, M. A., Kraus, V., Lems, Willem F., Meulenbelt, I., Pelletier, Jean Pierre, Raynauld, J. P., Reiter-Niesert, S., Rizzoli, R., Sandell, L. J., ... Reginster, Jean Yves. (2014) Value of biomarkers in osteoarthritis: Current status and perspectives. Postgraduate Medical Journal. 90(1061), pp. 171 - 178. https://doi.org/10.1136/postgradmedj-2013-203726rep
A meta-analysis of reference markers of bone turnover for prediction of fracture
Johansson, Helena, Oden, Anders, Kanis, John A., McCloskey, Eugene V., Morris, Howard A., Cooper, Cyrus and Vasikaran, Samuel. (2014) A meta-analysis of reference markers of bone turnover for prediction of fracture. Calcified Tissue International. 94(5), pp. 560 - 567. https://doi.org/10.1007/s00223-014-9842-y
Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention study (OSTPRE)
Sund, Reijo, Honkanen, Risto, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John and Kröger, Heikki. (2014) Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention study (OSTPRE). Calcified Tissue International. 95(1), pp. 39 - 45. https://doi.org/10.1007/s00223-014-9860-9
Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific Region
Wu, Chih-Hsing, McCloskey, Eugene V., Lee, Joon Kiong, Itabashi, Akira, Prince, Richard L., Yu, Wei, Li-Yu, Julie, Chionh, Siok Bee, Zhao, Yanling, Shin, Chan Soo, Gunawan, Tirtarahardja, Tsai, Keh-Sung, Chieng, Poon-Ung, Changlai, Sheng-Pin, Chan, Ding-Cheng, Chen, Jung-Fu, Tanner, S. Bobo, Hans, Didier B., Kanis, John A., ... Yang, Rong-Sen. (2014) Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific Region. Journal of Clinical Densitometry. 17(1), pp. 150 - 155. https://doi.org/10.1016/j.jocd.2013.06.002
The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Rizzoli, Rene, Stevenson, John C., Bauer, Jürgen M., Van Loon, Lucas J.C., Walrand, Stéphane, Kanis, John A., Cooper, Cyrus, Brandi, Maria Luisa, Diez-Perez, Adolfo and Reginster, Jean Yves. (2014) The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas. 79(1), pp. 122 - 132. https://doi.org/10.1016/j.maturitas.2014.07.005
Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: Estimations from a disease model
Piscitelli, P., Brandi, M., Cawston, H., Gauthier, A., Kanis, J. A., Compston, J., Borgstrom, F., Cooper, C. and McCloskey, E.. (2014) Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: Estimations from a disease model. Calcified Tissue International. 95(5), pp. 419 - 427. https://doi.org/10.1007/s00223-014-9910-3
An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Bruyère, Olivier, Cooper, Cyrus, Pelletier, Jean-Pierre, Branco, Jaime, Brandi, Maria Luisa, Guillemin, Francis, Hochberg, Marc C., Kanis, John A., Kvien, Tore K., Martel-Pelletier, Johanne, Rizzoli, Rene, Silverman, Stuart and Reginster, Jean-Yves. (2014) An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 44(3), pp. 253 - 263. https://doi.org/10.1016/j.semarthrit.2014.05.014
The application of health technology assessment in osteoporosis
Kanis, John A. and Hiligsmann, Mickaël. (2014) The application of health technology assessment in osteoporosis. Best Practice and Research: Clinical Endocrinology and Metabolism. 28(6), pp. 895 - 910. https://doi.org/10.1016/j.beem.2014.04.001
Goal-directed treatment of osteoporosis in Europe
Kanis, John A., McCloskey, Eugene, Branco, J., Brandi, Maria-Luisa, Dennison, Elaine M., Devogelaer, J.-P., Ferrari, S., Kaufman, J.-M., Papapoulos, S., Reginster, Jean-Yves and Rizzoli, R.. (2014) Goal-directed treatment of osteoporosis in Europe. Osteoporosis International. 25(11), pp. 2533 - 2543. https://doi.org/10.1007/s00198-014-2787-1
Waning predictive value of serum adiponectin for fracture risk in elderly men: MrOS Sweden
Johansson, Helena, Oden, Anders, Karlsson, Magnus, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes and Mellström, Dan. (2014) Waning predictive value of serum adiponectin for fracture risk in elderly men: MrOS Sweden. Osteoporosis International. 25(7), pp. 1831 - 1836. https://doi.org/10.1007/s00198-014-2654-0
Dietary Protein as a Trigger for Metabolic Adaptation
Van Loon, Luc. (2014) Dietary Protein as a Trigger for Metabolic Adaptation. In In R. J. Maughan (Ed.). The Encyclopaedia of Sports Medicine: An IOC Medical Commission Publication pp. 147 - 155 Wiley-Blackwell.
Challenges for the development of bone-forming agents in Europe
Kanis, John A., Rizzoli, Rene, Cooper, Cyrus and Reginster, Jean-Yves. (2014) Challenges for the development of bone-forming agents in Europe. Calcified Tissue International. 94(5), pp. 469 - 473. https://doi.org/10.1007/s00223-014-9844-9
The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans
Burd, N., Cermak, N., Kouw, Imre W. K., Gorissen, Stefan H. M., Gijsen, Annemie P. and Van Loon, Luc. (2014) The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans. Journal of Applied Physiology. 117(11), pp. 1363 - 1370. https://doi.org/10.1152/japplphysiol.00411.2014
Low holotranscobalamin and cobalamins predict incident fractures in elderly men: The MrOS Sweden
Lewerin, C. Lewerin, Nilsson-Ehle, H., Jacobsson, S., Johansson, Helena, Sundh, V., Karlsson, Magnus, Ljunggren, Östen, Lorentzon, Mattias, Kanis, John A., Lerner, Ulf H., Cummings, Steven R., Ohlsson, Claes and Mellström, Dan. (2014) Low holotranscobalamin and cobalamins predict incident fractures in elderly men: The MrOS Sweden. Osteoporosis International. 25(1), pp. 131 - 140. https://doi.org/10.1007/s00198-013-2527-y
A meta-analysis of the association of fracture risk and body mass index in women
Johansson, Helena, Kanis, John A., Oden, Anders, McCloskey, Eugene, Chapurlat, Roland D., Christiansen, Claus, Cummings, Steven R., Diez-Perez, A, Eisman, John A., Fujiwara, S., Glüer, C. C., Goltzman, David, Hans, D., Khaw, Kay Tee, Krieg, Marc Antoine, Kröger, Heikki, LaCroix, A. Z., Lau, E., Leslie, William D., ... Zillikens, M. Carola. (2014) A meta-analysis of the association of fracture risk and body mass index in women. Journal of Bone and Mineral Research. 29(1), pp. 223 - 233. https://doi.org/10.1002/jbmr.2017
The effect of latitude on the risk and seasonal variation in hip fracture in Sweden
Oden, Anders, Kanis, John A., McCloskey, Eugene V. and Johansson, Helena. (2014) The effect of latitude on the risk and seasonal variation in hip fracture in Sweden. Journal of Bone and Mineral Research. 29(10), pp. 2217 - 2223. https://doi.org/10.1002/jbmr.2250
A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Hiligsmann, Mickaël, Cooper, Cyrus, Guillemin, Francis, Hochberg, Marc C., Tugwell, Peter, Arden, Nigel, Berenbaum, Francis, Boers, Maarten, Boonen, Annelies, Branco, Jaime C., Maria-Luisa, Brandi, Bruyère, Olivier, Gasparik, Andrea Ildiko, Kanis, John A., Kvien, Tore K., Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Pinedo-Villanueva, Rafael, Pinto, Daniel, ... Reginster, Jean-Yves. (2014) A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 44(3), pp. 271 - 282. https://doi.org/10.1016/j.semarthrit.2014.06.005
Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
Moayyeri, Alireza, Hsu, Yi-Hsiang, Karasik, David, Estrada, Karol, Xiao, Su-Mei, Nielson, Carrie, Srikanth, Priya, Giroux, Sylvie, Wilson, Scott G., Zheng, Hou-Feng, Smith, Albert V., Pye, Stephen R., Leo, Paul J., Teumer, Alexander, Hwang, Joo-Yeon, Ohlsson, Claes, McGuigan, Fiona, Minster, Ryan L., Hayward, Caroline, ... Kaptoge, Stephen K.. (2014) Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Human Molecular Genetics. 23(11), pp. 3054 - 3068. https://doi.org/10.1093/hmg/ddt675
Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm
Kim, K., Svedbom, A., Luo, X., Sutradhar, S. and Kanis, John A.. (2014) Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm. Osteoporosis International. 25(1), pp. 325 - 337. https://doi.org/10.1007/s00198-013-2521-4
Worldwide uptake of FRAX
Kanis, John A., Johansson, Helena, Oden, Anders, Cooper, Cyrus, McCloskey, Eugene E. V., Epidemiology and Quality of Life Working Group of IOF, and Epidemiology and Quality of Life Working Group of IOF. (2014) Worldwide uptake of FRAX. Archives of Osteoporosis. 9(1), pp. 1 - 10. https://doi.org/10.1007/s11657-013-0166-8
The effect of a six-month resistance-type exercise training program on the course of high sensitive cardiac troponin T levels in (pre)frail elderly
Van Der Linden, Noreen, Tieland, Michael, Klinkenberg, Lieke J. J., Verdijk, Lex B., de Groot, Lisette C. P. G. M., Van Loon, Lucas, Van Dieijen-Visser, Marja P. and Meex, Steven J. R.. (2014) The effect of a six-month resistance-type exercise training program on the course of high sensitive cardiac troponin T levels in (pre)frail elderly. International Journal of Cardiology. 175(2), pp. 374 - 375. https://doi.org/10.1016/j.ijcard.2014.05.017
Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not frax independent risk factors for fracture
Leslie, William D., Orwoll, E., Nielson, Carrie M., Morin, Suzanne N., Majumdar, S. R., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2014) Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not frax independent risk factors for fracture. Journal of Bone and Mineral Research. 29(S1), pp. 2511 - 2519. https://doi.org/10.1002/jbmr.2280
Gaucher disease and bone manifestations
Marcucci, Gemma, Zimran, Ari, Bembi, Bruno, Kanis, John, Reginster, Jean-Yves, Rizzoli, Rene, Cooper, Cyrus and Brandi, Maria Luisa. (2014) Gaucher disease and bone manifestations. Calcified Tissue International. 95(6), pp. 477 - 494. https://doi.org/10.1007/s00223-014-9923-y
Trabecular bone score: A noninvasive analytical method based upon the DXA image
Silva, Barbara C., Leslie, William D., Resch, Heinrich, Lamy, Olivier, Lesnyak, Olga, Binkley, Neil, McCloskey, Eugene V., Kanis, John A. and Bilezikian, John P.. (2014) Trabecular bone score: A noninvasive analytical method based upon the DXA image. Journal of Bone and Mineral Research. 29(3), pp. 518 - 530. https://doi.org/10.1002/jbmr.2176
Can change in FRAX score be used to "treat to target"? A population-based cohort study
Leslie, William D., Majumdar, S. R., Lix, Lisa, Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2014) Can change in FRAX score be used to "treat to target"? A population-based cohort study. Journal of Bone and Mineral Research. 29(5), pp. 1074 - 1080. https://doi.org/10.1002/jbmr.2151
Updated fracture incidence rates for the Italian version of FRAX®
Piscitelli, P., Chitano, G., Johannson, Henning R., Brandi, Maria Luisa, Kanis, John A. and Black, Deborah. (2013) Updated fracture incidence rates for the Italian version of FRAX®. Osteoporosis International. 24(3), pp. 859 - 866. https://doi.org/10.1007/s00198-012-2021-y
Treatment of osteoporosis in men
Kaufman, J-M, Reginster, J-Y, Boonen, S., Brandi, M. L., Cooper, Cyrus, Dere, W., Devogelaer, J. P., Diez-Perez, A, Kanis, John A., McCloskey, Eugene, Mitlak, B., Orwoll, E, Ringe, J. D., Weryha, G. and Rizzoli, R. (2013) Treatment of osteoporosis in men. Bone. 53(1), pp. 134 - 144. https://doi.org/10.1016/j.bone.2012.11.018
Incidence of hip fracture in Barranquilla, Colombia, and the development of a Colombian FRAX model
Jaller, J. J., Jaller, J. J., Lechuga, J. A., Navarro, E., Johansson, Helena and Kanis, John. (2013) Incidence of hip fracture in Barranquilla, Colombia, and the development of a Colombian FRAX model. Calcified Tissue International. 93(1), pp. 15 - 22. https://doi.org/10.1007/s00223-013-9717-7
Value of biomarkers in osteoarthritis: Current status and perspectives
Lotz, M., Martel-Pelletier, Johanne, Christiansen, Claus, Brandi, Maria-Luisa, Bruyère, O., Chapurlat, Roland D., Collette, J., Cooper, Cyrus, Giacovelli, G., Kanis, John A., Karsdal, M. A., Kraus, V., Lems, Willem F., Meulenbelt, I., Pelletier, Jean-Pierre, Raynauld, J.-P., Reiter-Niesert, S., Rizzoli, R., Sandell, L. J., ... Reginster, Jean-Yves. (2013) Value of biomarkers in osteoarthritis: Current status and perspectives. Annals of the Rheumatic Diseases. 72(11), pp. 1756 - 1763. https://doi.org/10.1136/annrheumdis-2013-203726
Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013
Compston, J., Bowring, C., Cooper, A., Cooper, C., Davies, C., Francis, R., Kanis, J. A., Marsh, D., McCloskey, E. V., Reid, D. M. and Selby, P.. (2013) Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013. Maturitas. 75(4), pp. 392 - 396. https://doi.org/10.1016/j.maturitas.2013.05.013
Quality of life in sarcopenia and frailty
Rizzoli, Rene, Reginster, Jean-Yves, Arnal, Jean-Francois, Bautmans, Ivan, Beaudart, Charlotte, Bischoff-Ferrari, Heike, Biver, Emmanuel, Boonen, Steven, Brandi, Maria-Luisa, Chines, Arkadi, Cooper, Cyrus, Epstein, Sol, Fielding, Roger A., Goodpaster, Bret, Kanis, John A., Kaufman, J., Laslop, A., Malafarina, Vincenzo, Mañas, Leocadio Rodriguez, ... Bruyère, O.. (2013) Quality of life in sarcopenia and frailty. Calcified Tissue International. 93(2), pp. 101 - 120. https://doi.org/10.1007/s00223-013-9758-y
Vitamin D supplementation in elderly or postmenopausal women: A 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Rizzoli, R., Boonen, S., Brandi, Maria-Luisa, Bruyère, O., Cooper, Cyrus, Kanis, John A., Kaufman, J.-M., Ringe, J. D., Weryha, G. and Reginster, Jean Yves. (2013) Vitamin D supplementation in elderly or postmenopausal women: A 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Current Medical Research and Opinion. 29(4), pp. 305 - 313. https://doi.org/10.1185/03007995.2013.766162
Incidence of hip fracture in Romania and the development of a Romanian FRAX model
Grigorie, Daniel, Sucaliuc, Alina, Johansson, Helena, Kanis, John A. and McCloskey, Eugene. (2013) Incidence of hip fracture in Romania and the development of a Romanian FRAX model. Calcified Tissue International. 92(5), pp. 429 - 436. https://doi.org/10.1007/s00223-013-9697-7
Assessing the impact of osteoporosis on the burden of hip fractures
Oden, Anders, McCloskey, Eugene V., Johansson, Helena and Kanis, John A.. (2013) Assessing the impact of osteoporosis on the burden of hip fractures. Calcified Tissue International. 92(1), pp. 42 - 49. https://doi.org/10.1007/s00223-012-9666-6
The role of amino acids in skeletal muscle adaptation to exercise
Aguirre, Nick, Van Loon, Lucas and Baar, Keith. (2013) The role of amino acids in skeletal muscle adaptation to exercise. In In E. Isolauri, P.M. Sherman and W. A. Walker (Ed.). Nestle Nutrition Institute workshop series pp. 85 - 102 S. Karger AG. https://doi.org/10.1159/000350261
Health technology assessment in osteoporosis
Hiligsmann, Mickaël, Kanis, John A., Compston, Juliet, Cooper, Cyrus, Flamion, Bruno, Bergmann, Pierre, Body, Jean-Jaques, Boonen, Steven, Bruyère, Olivier, Devogelaer, Jean-Pierre, Goemaere, Stefan, Kaufman, Jean-Marc, Rozenberg, Serge and Reginster, Jean-Yves. (2013) Health technology assessment in osteoporosis. Calcified Tissue International. 93(1), pp. 1 - 14. https://doi.org/10.1007/s00223-013-9724-8
FRAX-based intervention and assessment thresholds for osteoporosis in Romania
Grigorie, Daniel, Sucaliuc, Alina, Johansson, Helena, Kanis, John A. and McCloskey, Eugene. (2013) FRAX-based intervention and assessment thresholds for osteoporosis in Romania. Archives of Osteoporosis. 8(2017-02-01), pp. 1 - 5. https://doi.org/10.1007/s11657-013-0164-x
Selection of women aged 50-64yr for bone density measurement
Leslie, William D., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2013) Selection of women aged 50-64yr for bone density measurement. Journal of Clinical Densitometry. 16(4), pp. 570 - 578. https://doi.org/10.1016/j.jocd.2013.01.004
Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Hiligsmann, Mickaël, Cooper, Cyrus, Arden, Nigel, Boers, Maarten, Branco, Jaime C., Brandi, Maria Luisa, Bruyère, Olivier, Guillemin, Francis, Hochberg, Marc C., Hunter, David J., Kanis, John A., Kvien, Tore K., Laslop, Andrea, Pelletier, Jean-Pierre, Pinto, Daniel, Reiter-Niesert, Susanne, Rizzoli, Rene, Rovati, Lucio C., Severens, Johan L., ... Reginster, Jean-Yves. (2013) Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 43(3), pp. 303 - 313. https://doi.org/10.1016/j.semarthrit.2013.07.003
Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake
Nabuurs, C. I., Choe, C. U., Veltien, A., Kan, H. E., Van Loon, Luc, Rodenburg, R. J. T., Matschke, J., Wieringa, B., Kemp, G. J., Isbrandt, D. and Heerschap, A.. (2013) Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake. Journal of Physiology. 591(2), pp. 571 - 592. https://doi.org/10.1113/jphysiol.2012.241760
Osteoporosis in the European Union: A compendium of country-specific reports
Svedbom, A., Hernlund, E., Ivergård, M., Compston, Juliet E., Cooper, Cyrus, Stenmark, J., McCloskey, Eugene V., Jönsson, Bengt, Kanis, John A., The EU review panel of the IOF, and The EU review panel of the IOF. (2013) Osteoporosis in the European Union: A compendium of country-specific reports. Archives of Osteoporosis. 8(1-2), pp. 1 - 218. https://doi.org/10.1007/s11657-013-0137-0
How to define responders in osteoarthritis
Cooper, Cyrus, Adachi, Jonathan D., Bardin, Thomas, Berenbaum, Francis, Flamion, Bruno, Jonsson, Helgi, Kanis, John A., Pelousse, Franz, Lems, Willem F., Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Reiter, Susanne, Reginster, Jean-Yves, Rizzoli, Rene and Bruyère, Olivier. (2013) How to define responders in osteoarthritis. Current Medical Research and Opinion. 29(6), pp. 719 - 729. https://doi.org/10.1185/03007995.2013.792793
The osteoporosis treatment gap in Romania
Kanis, John, Hernlund, E., Svedbom, Axel, Ivergãrd, M. and Grigorie, Daniel. (2013) The osteoporosis treatment gap in Romania. Acta Endocrinologica. 9(4), pp. 509 - 514. https://doi.org/10.4183/aeb.2013.509
European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, John A., McCloskey, Eugene V., Johansson, Helena, Cooper, Cyrus, Rizzoli, R. and Reginster, Jean Yves. (2013) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 24(1), pp. 23 - 57. https://doi.org/10.1007/s00198-012-2074-y
Intervention thresholds for denosumab in the UK using a FRAX®-based cost-effectiveness analysis
Ström, O., Jönsson, Bengt and Kanis, John A.. (2013) Intervention thresholds for denosumab in the UK using a FRAX®-based cost-effectiveness analysis. Osteoporosis International. 24(4), pp. 1491 - 1502. https://doi.org/10.1007/s00198-012-2115-6
Tools in the assessment of sarcopenia
Cooper, C., Fielding, R., Visser, M., Van Loon, L. J., Rolland, Y., Orwoll, E., Reid, K., Boonen, S., Dere, W., Epstein, S., Mitlak, B., Tsouderos, Y., Sayer, A. A., Rizzoli, R., Reginster, J. Y. and Kanis, J. A.. (2013) Tools in the assessment of sarcopenia. Calcified Tissue International. 93(3), pp. 201 - 210. https://doi.org/10.1007/s00223-013-9757-z
Elderly men and women benefit equally from prolonged resistance-type exercise training
Leenders, Marika, Verdijk, Lex B., van der Hoeven, Letty, Van Kranenburg, Janneau, Nilwik, Rachel and Van Loon, Luc. (2013) Elderly men and women benefit equally from prolonged resistance-type exercise training. Journals of Gerontology: Series A Biological Sciences and Medical Sciences. 68(7), pp. 769 - 779. https://doi.org/10.1093/gerona/gls241
Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee
Dempster, David W., Compston, Juliet E., Drezner, Marc K., Glorieux, Francis H., Kanis, John A., Malluche, Hartmut, Meunier, Pierre J., Ott, Susan M., Recker, Robert R. and Parfitt, A. Michael. (2013) Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee. Journal of Bone and Mineral Research. 28(1), pp. 2 - 17. https://doi.org/10.1002/jbmr.1805
Validity and Reliability of Tools to Measure Muscle Mass, Strength, and Physical Performance in Community-Dwelling Older People: A Systematic Review
Mijnarends, Donja M., Meijers, Judith M. M., Halfens, Ruud J. G., Borg, Sovianne Ter, Luiking, Yvette C., Verlaan, Sjors, Schoberer, Daniela, Cruz-Jentoft, Alfonso J., Van Loon, Luc and Schols, Jos M. G. A.. (2013) Validity and Reliability of Tools to Measure Muscle Mass, Strength, and Physical Performance in Community-Dwelling Older People: A Systematic Review. Journal of the American Medical Directors Association. 14(3), pp. 170 - 178. https://doi.org/10.1016/j.jamda.2012.10.009
SCOPE: A scorecard for osteoporosis in Europe
Kanis, John A., Borgström, F., Compston, Juliet E., Dreinhöfer, K., Nolte, E., Jonsson, L., Le, Willem F., McCloskey, Eugene, Rizzoli, R. and Stenmark, J.. (2013) SCOPE: A scorecard for osteoporosis in Europe. Archives of Osteoporosis. 8(42767), pp. 1 - 63. https://doi.org/10.1007/s11657-013-0144-1
Substantial differences between organ and muscle specific tracer incorporation rates in a lactating dairy cow
Burd, N, Hamer, Henrike M., Pennings, Bart, Pellikaan, Wilbert F., Senden, Joan M., Gijsen, Annemie P. and Van Loon, Luc. (2013) Substantial differences between organ and muscle specific tracer incorporation rates in a lactating dairy cow. PLoS ONE. 8(6), pp. 1 - 10. https://doi.org/10.1371/journal.pone.0068109
Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: A randomized trial
Klinkenberg, Lieke J. J., Res, Peter T., Haenen, Guido R., Bast, Aalt, Van Loon, Luc, Van Dieijen-Visser, Marja P. and Meex, Steven J. R.. (2013) Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: A randomized trial. PLoS ONE. 8(11), pp. 1 - 6. https://doi.org/10.1371/journal.pone.0079280
Inflammatory bowel disease and the risk of fracture after controlling for FRAX
Targownik, Laura E., Bernstein, Charles N., Nugent, Zoann, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John A. and Leslie, William D.. (2013) Inflammatory bowel disease and the risk of fracture after controlling for FRAX. Journal of Bone and Mineral Research. 28(5), pp. 1007 - 1013. https://doi.org/10.1002/jbmr.1848
Osteoporosis in the European Union: Medical management, epidemiology and economic burden: A report prepared in collaboration with the International Osteoporosis Foundation IOF and the European Federation of Pharmaceutical Industry Associations EFPIA
Hernlund, E., Svedbom, A., Ivergård, M., Compston, Juliet E., Cooper, Cyrus, Stenmark, J., McCloskey, Eugene V., Jönsson, Bengt and Kanis, John A.. (2013) Osteoporosis in the European Union: Medical management, epidemiology and economic burden: A report prepared in collaboration with the International Osteoporosis Foundation IOF and the European Federation of Pharmaceutical Industry Associations EFPIA. Archives of Osteoporosis. 8(1-2), pp. 1 - 115. https://doi.org/10.1007/s11657-013-0136-1
Standardising the descriptive epidemiology of osteoporosis: Recommendations from the Epidemiology and Quality of Life Working Group of IOF
Kanis, John A., Adachi, Jonathan D., Cooper, Cyrus, Clark, P., Cummings, Steven R., Diaz-Curiel, M., Harvey, Nicholas C., Hiligsmann, Mickaël, Papaioannou, A., Pierroz, D. D., Silverman, S. L. and Szulc, P.. (2013) Standardising the descriptive epidemiology of osteoporosis: Recommendations from the Epidemiology and Quality of Life Working Group of IOF. Osteoporosis International. 24(11), pp. 2763 - 2764. https://doi.org/10.1007/s00198-013-2413-7
Development and application of FRAX in the management of osteoporosis in Ireland
McGowan, B., Kanis, John A., Johansson, Helena, Silke, C. and Whelan, B.. (2013) Development and application of FRAX in the management of osteoporosis in Ireland. Archives of Osteoporosis. 8(2017-02-01), pp. 1 - 6. https://doi.org/10.1007/s11657-013-0146-z
What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?
Pelletier, Jean Pierre, Cooper, Cyrus, Peterfy, C., Reginster, Jean Yves, Brandi, Maria Luisa, Bruyère, O., Chapurlat, Roland D., Cicuttini, Flavia, Conaghan, P. G., Doherty, M., Genant, H., Giacovelli, G., Hochberg, Marc, Hunter, David J., Kanis, John A., Kloppenburg, M., Laredo, J. D., McAlindon, T., Nevitt, M., ... Guermazi, A.. (2013) What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis? Annals of the Rheumatic Diseases. 72(10), pp. 1594 - 1604. https://doi.org/10.1136/annrheumdis-2013-203631
Assessment of health claims in the field of bone: A view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Bruyère, O., Rizzoli, R, Coxam, V., Avouac, B., Chevalier, T., Fabien-Soulé, V., Kanis, John A., Kaufman, J.-M., Tsouderos, Y. and Reginster, Jean-Yves. (2012) Assessment of health claims in the field of bone: A view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporosis International. 23(1), pp. 193 - 199. https://doi.org/10.1007/s00198-011-1561-x
Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model
Stepan, Jan J., Vaculik, Jan, Pavelka, Karel, Zofka, Jan, Johansson, Helena and Kanis, John A.. (2012) Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model. Calcified Tissue International. 90(5), pp. 365 - 372. https://doi.org/10.1007/s00223-012-9582-9
Implications for fracture healing of current and new osteoporosis treatments: An ESCEO consensus paper
Goldhahn, J., Féron, J. M., Kanis, J., Papapoulos, S., Reginster, J-Y., Rizzoli, R., Dere, W., Mitlak, B., Tsouderos, Y. and Boonen, S.. (2012) Implications for fracture healing of current and new osteoporosis treatments: An ESCEO consensus paper. Calcified Tissue International. 90(5), pp. 343 - 353. https://doi.org/10.1007/s00223-012-9587-4
A systematic review of hip fracture incidence and probability of fracture worldwide
Kanis, John A., Oden, Anders, McCloskey, Eugene V., Johansson, Helena, Wahl, D. A. and Cooper, Cyrus. (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis International. 23(9), pp. 2239 - 2256. https://doi.org/10.1007/s00198-012-1964-3
Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk?
Klinkenberg, Lieke J. J., Res, Peter T., Van Loon, Lucas, Van Dieijen-Visser, Marja P. and Meex, Steven J. R.. (2012) Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk? International Journal of Cardiology. 158(1), pp. 129 - 131. https://doi.org/10.1016/j.ijcard.2012.04.050
Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden
Johansson, Helena Johansson, Oden, Anders, Kanis, John A., McCloskey, Eugene, Lorentzon, Mattias, Ljunggren, Östen, Karlsson, Magnus, Thorsby, P. M., Tivesten, A., Barrett-Connor, Elizabeth, Ohlsson, Claes and Mellström, Dan. (2012) Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden. Osteoporosis International. 23(3), pp. 991 - 999. https://doi.org/10.1007/s00198-011-1809-5
Long-term treatment of osteoporosis in postmenopausal women: A review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
Cooper, Cyrus, Reginster, Jean-Yves, Cortet, B., Diaz-Curiel, M., Lorenc, R. S., Kanis, John A. and Rizzoli, R.. (2012) Long-term treatment of osteoporosis in postmenopausal women: A review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Current Medical Research and Opinion. 28(3), pp. 475 - 491. https://doi.org/10.1185/03007995.2012.663750
Does osteoporosis therapy invalidate FRAX for fracture prediction?
Leslie, William D., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012) Does osteoporosis therapy invalidate FRAX for fracture prediction? Journal of Bone and Mineral Research. 27(6), pp. 1243 - 1251. https://doi.org/10.1002/jbmr.1582
Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland
Lippuner, K., Johansson, Helena, Borgström, F., Kanis, John A. and Rizzoli, R.. (2012) Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland. Osteoporosis International. 23(11), pp. 2579 - 2589. https://doi.org/10.1007/s00198-011-1869-6
Antidepressant medications and osteoporosis
Rizzoli, R., Cooper, C., Reginster, Jean Yves, Abrahamsen, Bo, Adachi, Jonathan, Brandi, Maria Luisa, Bruyère, O., Compston, Juliet E., Ducy, P., Ferrari, S., Harvey, Nicholas C., Kanis, John A., Karsenty, G., Laslop, A., Rabenda, V. and Vestergaard, P.. (2012) Antidepressant medications and osteoporosis. Bone. 51(3), pp. 606 - 613. https://doi.org/10.1016/j.bone.2012.05.018
Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: Estimations from a disease model
Cawston, H., Maravic, M., Fardellone, P., Gauthier, A., Kanis, John A., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2012) Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: Estimations from a disease model. Archives of Osteoporosis. 7(2017-02-01), pp. 237 - 246. https://doi.org/10.1007/s11657-012-0102-3
A comparative study of using non-hip bone density inputs with FRAX®
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012) A comparative study of using non-hip bone density inputs with FRAX®. Osteoporosis International. 23(3), pp. 853 - 860. https://doi.org/10.1007/s00198-011-1814-8
Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Senocak, M., Johansson, Helena and Kanis, John A.. (2012) Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study. Osteoporosis International. 23(3), pp. 949 - 955. https://doi.org/10.1007/s00198-011-1655-5
High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS) Sweden
Johansson, Helena, Oden, Anders, Lerner, Ulf H., Jutberger, Hans, Lorentzon, Mattias, Barrett-Connor, Elizabeth, Karlsson, Magnus, Ljunggren, Östen, Smith, Ulf, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes and Mellstrom, Dan. (2012) High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS) Sweden. Journal of Bone and Mineral Research. 27(6), pp. 1390 - 1396. https://doi.org/10.1002/jbmr.1591
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
Lim, Stephen S., Vos, Theo, Flaxman, Abraham D., Danaei, Goodarz, Shibuya, Kenji, Adair-Rohani, Heather, AlMazroa, Mohammad A., Amann, Markus, Anderson, H. Ross, Andrews, Kathryn G., Aryee, Martin, Atkinson, Charles, Bacchus, Loraine J., Bahalim, Adil N., Balakrishnan, Kalpana, Balmes, John, Barker-Collo, Suzanne, Baxter, Amanda, Bell, Michelle L., ... Ezzati, Majid. (2012) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 380, pp. 2224 - 2260. https://doi.org/10.1016/S0140-6736(12)61766-8
Fracture risk assessment without bone density measurement in routine clinical practice
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012) Fracture risk assessment without bone density measurement in routine clinical practice. Osteoporosis International. 23(1), pp. 75 - 85. https://doi.org/10.1007/s00198-011-1747-2
A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis
Lekamwasam, S., Adachi, Jonathan D., Agnusdei, D., Bilezikian, J. P., Boonen, S., Borgström, F., Cooper, Cyrus, Diez-Perez, A., Eastell, Richard, Hofbauer, L. C., Kanis, John A., Langdahl, B. L., Lesnyak, Olga, Lorenc, R. S., McCloskey, Eugene, Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, Stuart H., ... Compston, Juliet E.. (2012) A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. Osteoporosis International. 23(9), pp. 2257 - 2276. https://doi.org/10.1007/s00198-012-1958-1
FRAX® with and without bone mineral density
Kanis, John A., McCloskey, Eugene, Johansson, Helena, Oden, Anders and Leslie, William D.. (2012) FRAX® with and without bone mineral density. Calcified Tissue International. 90(1), pp. 1 - 13. https://doi.org/10.1007/s00223-011-9544-7
Epidemiology of fracture in the Russian Federation and the development of a FRAX model
Lesnyak, Olga, Ershova, Olga, Belova, Ksenia, Gladkova, Elena, Sinitsina, Olga, Ganert, Olga, Romanova, Marina, Khodirev, Vitalij, Johansson, Helena, McCloskey, Eugene and Kanis, John A.. (2012) Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Archives of Osteoporosis. 7(2017-02-01), pp. 67 - 73. https://doi.org/10.1007/s11657-012-0082-3
Pitfalls in the external validation of FRAX
Kanis, John A., Oden, Anders, Johansson, Helena and McCloskey, Eugene. (2012) Pitfalls in the external validation of FRAX. Osteoporosis International. 23(2), pp. 423 - 431. https://doi.org/10.1007/s00198-011-1846-0
The single biopsy approach is reliable for the measurement of muscle protein synthesis rates in vivo in older men
Burd, N., Pennings, Bart, Groen, Bart B. L., Gijsen, Annemie P., Senden, Joan M. and Van Loon, Luc. (2012) The single biopsy approach is reliable for the measurement of muscle protein synthesis rates in vivo in older men. Journal of Applied Physiology. 113(6), pp. 896 - 902. https://doi.org/10.1152/japplphysiol.00513.2012
Inspanningstherapie bij type 2 diabetes: is dagelijkse inspanning noodzakelijk om glycemische controle te optimaliseren?
van Dijk, Jan W., Tummers, Kyra, Stehouwer, Coen D.A., Hartgens, Fred and van Loon, Luc. (2012) Inspanningstherapie bij type 2 diabetes: is dagelijkse inspanning noodzakelijk om glycemische controle te optimaliseren? Nederlands Tijdschrift voor Diabetologie. 10(2), pp. 60 - 61. https://doi.org/10.1007/s12467-012-0021-3
Burden of postmenopausal osteoporosis in Germany: Estimations from a disease model
Gauthier, A., Kanis, John A., Jiang, Yling, Dreinhöfer, K., Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2012) Burden of postmenopausal osteoporosis in Germany: Estimations from a disease model. Archives of Osteoporosis. 7(2017-02-01), pp. 209 - 218. https://doi.org/10.1007/s11657-012-0099-7
High fracture probability with FRAX® usually indicates densitometric osteoporosis: Implications for clinical practice
Leslie, William D., Majumdar, S. R., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2012) High fracture probability with FRAX® usually indicates densitometric osteoporosis: Implications for clinical practice. Osteoporosis International. 23(1), pp. 391 - 397. https://doi.org/10.1007/s00198-011-1592-3
Potential extensions of the US FRAX algorithm
Melton, Lisa Joseph, Atkinson, Elizabeth J., Achenbach, Sara J., Kanis, John A., Therneau, Terry M., Johansson, Helena, Khosla, Sundeep and Amin, Shreyasee. (2012) Potential extensions of the US FRAX algorithm. Journal of Osteoporosis. 2012, pp. 1 - 8. https://doi.org/10.1155/2012/528790
A reappraisal of generic bisphosphonates in osteoporosis
Kanis, John A., Reginster, Jean Yves, Kaufman, J.-M., Ringe, J.-D., Adachi, Jonathan D., Hiligsmann, Mickaël, Rizzoli, R. and Cooper, Cyrus. (2012) A reappraisal of generic bisphosphonates in osteoporosis. Osteoporosis International. 23(1), pp. 213 - 221. https://doi.org/10.1007/s00198-011-1796-6
FRAX underestimates fracture risk in patients with diabetes
Giangregorio, Lora M., Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012) FRAX underestimates fracture risk in patients with diabetes. Journal of Bone and Mineral Research. 27(2), pp. 301 - 308. https://doi.org/10.1002/jbmr.556
FRAX® probabilities and risk of major osteoporotic fracture in France
Couris, C. M., Chapurlat, Roland D., Kanis, John A., Johansson, Helena, Burlet, N., Delmas, P. D. and Schott, A. M.. (2012) FRAX® probabilities and risk of major osteoporotic fracture in France. Osteoporosis International. 23(9), pp. 2321 - 2327. https://doi.org/10.1007/s00198-011-1883-8
Management of glucocorticoid-induced osteoporosis
Rizzoli, R., Adachi, J. D., Cooper, C., Dere, W., Devogelaer, J. P., Diez-Perez, A., Kanis, J. A., Laslop, A., Mitlak, B., Papapoulos, S., Ralston, S., Reiter, S., Werhya, G. and Reginster, J. Y.. (2012) Management of glucocorticoid-induced osteoporosis. Calcified Tissue International. 91(4), pp. 225 - 243. https://doi.org/10.1007/s00223-012-9630-5
Vitamin D with calcium reduces mortality: Patient level pooled analysis of 70,528 patients from eight major vitamin D trials
Rejnmark, Lars, Avenell, Alison, Masud, Tahir, Anderson, Frazer, Meyer, Haakon E., Sanders, Kerrie M., Salovaara, Kari, Cooper, Cyrus, Smith, Helen E., Jacobs, Elizabeth T., Torgerson, David, Jackson, Rebecca D., Manson, JoAnn E., Brixon, Kim, Mosekilde, Leif, Robbins, John A., Francis, Roger M. and Abrahamsen, Bo. (2012) Vitamin D with calcium reduces mortality: Patient level pooled analysis of 70,528 patients from eight major vitamin D trials. Journal of Clinical Endocrinology and Metabolism. 97(8), pp. 2670 - 2681. https://doi.org/10.1210/jc.2011-3328
The impact of a FRAX-based intervention threshold in Turkey: The FRAX-TURK study
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Johansson, Helena, McCloskey, Eugene, Kanis, John A., Turkish Osteoporosis Society, and Turkish Osteoporosis Society. (2012) The impact of a FRAX-based intervention threshold in Turkey: The FRAX-TURK study. Archives of Osteoporosis. 7(2017-02-01), pp. 229 - 235. https://doi.org/10.1007/s11657-012-0101-4
Type 2 diabetes and bone
Leslie, William D., Rubin, Mishaela R., Schwartz, Ann V. and Kanis, John A.. (2012) Type 2 diabetes and bone. Journal of Bone and Mineral Research. 27(11), pp. 2231 - 2237. https://doi.org/10.1002/jbmr.1759
FRAX updates 2012
McCloskey, Eugene V. and Kanis, John A.. (2012) FRAX updates 2012. Current Opinion in Rheumatology. 24(5), pp. 554 - 560. https://doi.org/10.1097/BOR.0b013e328356d2f5
A comparison of case-finding strategies in the UK for the management of hip fractures
Johansson, Helena, Kanis, John A., Oden, Anders, Compston, Juliet E. and McCloskey, Eugene. (2012) A comparison of case-finding strategies in the UK for the management of hip fractures. Osteoporosis International. 23(3), pp. 907 - 915. https://doi.org/10.1007/s00198-011-1864-y
The potential impact of the National Osteoporosis Foundation guidance on treatment eligibility in the USA: An update in NHANES 2005-2008
Dawson-Hughes, Bess, Looker, A. C., Tosteson, Anna N. A., Johansson, Helena, Kanis, John A. and Melton, Lisa. (2012) The potential impact of the National Osteoporosis Foundation guidance on treatment eligibility in the USA: An update in NHANES 2005-2008. Osteoporosis International. 23(3), pp. 811 - 820. https://doi.org/10.1007/s00198-011-1694-y
Fracture risk assessment
McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John A.. (2012) Fracture risk assessment. Clinical Biochemistry. 45(12), pp. 887 - 893. https://doi.org/10.1016/j.clinbiochem.2012.05.001
An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis
Lekamwasam, S., Adachi, Jonathan D., Agnusdei, D., Bilezikian, J P., Boonen, S., Borgström, F., Cooper, Cyrus, Perez, A. Diez, Eastell, Richard, Hofbauer, L. C., Kanis, John A., Langdahl, B. L., Lesnyak, Olga, Lorenc, R. S., McCloskey, Eugene, Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, Stuart H., ... Compston, Juliet E.. (2012) An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis. Archives of Osteoporosis. 7(2017-02-01), pp. 25 - 30. https://doi.org/10.1007/s11657-012-0070-7
Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Austin, Matthew S., Siris, E. S., Wang, Andrea, Lewiecki, E. Michael, Lorenc, R. S., Libanati, Cesar and Kanis, John A.. (2012) Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX. Journal of Bone and Mineral Research. 27(7), pp. 1480 - 1486. https://doi.org/10.1002/jbmr.1606
The distribution of FRAX®-based probabilities in women from Japan
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2012) The distribution of FRAX®-based probabilities in women from Japan. Journal of Bone and Mineral Metabolism. 30(6), pp. 700 - 705. https://doi.org/10.1007/s00774-012-0371-3
A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study
Shepstone, L., Fordham, R., Lenaghan, E., Harvey, I., Cooper, Cyrus, Gittoes, Neil, Heawood, A., Peters, T. J., O¿Neill, T. W., Torgerson, David, Holland, R., Howe, A., Marshall, T., Kanis, John A. and McCloskey, Eugene. (2012) A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study. Osteoporosis International. 23(10), pp. 2507 - 2515. https://doi.org/10.1007/s00198-011-1876-7
Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial
Tieland, Michael, De Rest, Ondine Van, Dirks, Marlou L., Van Der Zwalu, Nikita L., Mensink, Marco, Van Loon, Luc and de Groot, Lisette C. P. G. M.. (2012) Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of the American Medical Directors Association. 13(8), pp. 720 - 726. https://doi.org/10.1016/j.jamda.2012.07.005
Frailty and sarcopenia: Definitions and outcome parameters
Cooper, Cyrus, Dere, W., Evans, William J., Kanis, John A., Rizzoli, R, Sayer, A. A., Sieber, C. C., Kaufman, J, Van Kan, G. Abellan, Boonen, S., Adachi, Jonathan, Mitlak, B., Tsouderos, Y., Rolland, Y. and Reginster, Jean Yves. (2012) Frailty and sarcopenia: Definitions and outcome parameters. Osteoporosis International. 23(7), pp. 1839 - 1848. https://doi.org/10.1007/s00198-012-1913-1
Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures
Lalmohamed, A., Welsing, P. M. J., Lems, Willem F., Jacobs, J. W. G., Kanis, John A., Johansson, Helena, De Boer, A. and De Vries, F.. (2012) Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures. Osteoporosis International. 23(3), pp. 861 - 869. https://doi.org/10.1007/s00198-011-1852-2
Fracture prediction and calibration of a Canadian FRAX® tool: A population-based report from CaMos
Fraser, L.-A., Langsetmo, L., Berger, C., Ioannidis, G., Goltzman, David, Adachi, Jonathan D., Papaioannou, A., Josse, R. G., Kovacs, C. S., Olszynski, W. P., Towheed, T., Hanley, David A., Kaiser, S. M., Prior, J., Jamal, S., Kreiger, N., Brown, J. P., Johansson, Helena, Oden, Anders, ... Leslie, William D.. (2011) Fracture prediction and calibration of a Canadian FRAX® tool: A population-based report from CaMos. Osteoporosis International. 22(3), pp. 829 - 837. https://doi.org/10.1007/s00198-010-1465-1
A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX®
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2011) A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX®. Osteoporosis International. 22(8), pp. 2347 - 2355. https://doi.org/10.1007/s00198-010-1474-0
Evaluation of FRAX to characterise fracture risk in Poland
Czerwinski, E., Kanis, John A., Osieleniec, J., Kumorek, A., Milert, A., Johansson, Helena, McCloskey, Eugene V. and Gorkiewicz, M.. (2011) Evaluation of FRAX to characterise fracture risk in Poland. Osteoporosis International. 22(9), pp. 2507 - 2512. https://doi.org/10.1007/s00198-010-1502-0
Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report
Rizzoli, R, Åkesson, K., Bouxsein, M. L., Kanis, John A., Napoli, N., Papapoulos, S., Reginster, Jean Yves and Cooper, Cyrus. (2011) Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporosis International. 22(2), pp. 373 - 390. https://doi.org/10.1007/s00198-010-1453-5
Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment
Leslie, William D., Lix, Lisa M., Langsetmo, L., Berger, C., Goltzman, David, Hanley, David A., Adachi, J. D., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011) Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment. Osteoporosis International. 22(3), pp. 817 - 827. https://doi.org/10.1007/s00198-010-1464-2
Interpretation and use of FRAX in clinical practice
Kanis, John A., Hans, D., Cooper, Cyrus, Baim, Sanford, Bilezikian, J. P., Binkley, Neil, Cauley, Jane A., Compston, Juliet E., Dawson-Hughes, Bess, Fuleihan, Ghada El-Hajj, Johansson, Helena, Leslie, William D., Lewiecki, E. Michael, Luckey, Marjorie M., Oden, Anders, Papapoulos, S., Poiana, Catalina, Rizzoli, R, Wahl, D. A. and McCloskey, Eugene. (2011) Interpretation and use of FRAX in clinical practice. Osteoporosis International. 22(9), pp. 2395 - 2411. https://doi.org/10.1007/s00198-011-1713-z
FRAX - modell för att beräkna 10-årsrisken för fraktur
Johansson, Helena, Kanis, John, Ljunggren, Östen, Ström, O., Svensson, Olle and Mellström, Dan. (2011) FRAX - modell för att beräkna 10-årsrisken för fraktur. Lakartidningen. 108(7), pp. 336 - 339.
Increasing age- and sex-specific rates of hip fracture in Mexico: A survey of the Mexican institute of social security
Johansson, Helena, Clark, P., Carlos, F., Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011) Increasing age- and sex-specific rates of hip fracture in Mexico: A survey of the Mexican institute of social security. Osteoporosis International. 22(8), pp. 2359 - 2364. https://doi.org/10.1007/s00198-010-1475-z
Epidemiological burden of postmenopausal osteoporosis in the UK from 2010 to 2021: Estimations from a disease model
Gauthier, A., Kanis, John A., Jiang, Yling, Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2011) Epidemiological burden of postmenopausal osteoporosis in the UK from 2010 to 2021: Estimations from a disease model. Archives of Osteoporosis. 6(2017-02-01), pp. 179 - 188. https://doi.org/10.1007/s11657-011-0063-y
Joint official positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. Executive Summary of the 2010 Position Development Conference on Interpretation and Use of FRAX® in Clinical Practice
Hans, Dieder B. L., Kanis, John A., Baim, Sanford, Bilezikian, John P., Binkley, Neil, Cauley, Jane A., Compston, Juliet E., Cooper, Cyrus, Dawson-Hughes, Bess, El-Hajj Fuleihan, Ghada, Leslie, William D., Lewiecki, E. Michael, Luckey, Marjorie M., McCloskey, Eugene V., Papapoulos, Socrates E., Poiana, Catalina and Rizzoli, Rene. (2011) Joint official positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. Executive Summary of the 2010 Position Development Conference on Interpretation and Use of FRAX® in Clinical Practice. Journal of Clinical Densitometry. 14(3), pp. 171 - 180. https://doi.org/10.1016/j.jocd.2011.05.007
Development and validation of a disease model for postmenopausal osteoporosis
Gauthier, A., Kanis, John A., Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2011) Development and validation of a disease model for postmenopausal osteoporosis. Osteoporosis International. 22(3), pp. 771 - 780. https://doi.org/10.1007/s00198-010-1358-3
Partial adherence: A new perspective on health economic assessment in osteoporosis
Kanis, John A., Cooper, Cyrus, Hiligsmann, Mickaël, Rabenda, V., Reginster, Jean-Yves and Rizzoli, R.. (2011) Partial adherence: A new perspective on health economic assessment in osteoporosis. Osteoporosis International. 22(10), pp. 2565 - 2573. https://doi.org/10.1007/s00198-011-1668-0
The application of FRAX® to determine intervention thresholds in osteoporosis treatment in Poland
Badurski, Janusz E., Kanis, John A., Johansson, Helena, Dobrenko, Andrzej, Nowak, Nonna A., Daniluk, Stefan and Jezienicka, Elzbieta. (2011) The application of FRAX® to determine intervention thresholds in osteoporosis treatment in Poland. Polish Archives of Internal Medicine. 121(5), pp. 148 - 155.
Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis
Jönsson, Bengt, Ström, O., Eisman, John A., Papaioannou, A., Siris, E. S., Tosteson, Anna N. A. and Kanis, John A.. (2011) Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis. Osteoporosis International. 22(3), pp. 967 - 982. https://doi.org/10.1007/s00198-010-1424-x
Osteoporosis: Burden, health care provision and opportunities in the EU
Ström, O., Borgström, F., Kanis, John A., Compston, Juliet E., Cooper, Cyrus, McCloskey, Eugene V. and Jönsson, B.. (2011) Osteoporosis: Burden, health care provision and opportunities in the EU. Archives of Osteoporosis. 6(42767), pp. 59 - 155. https://doi.org/10.1007/s11657-011-0060-1
Guidance for the adjustment of FRAX according to the dose of glucocorticoids
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2011) Guidance for the adjustment of FRAX according to the dose of glucocorticoids. Osteoporosis International. 22(3), pp. 809 - 816. https://doi.org/10.1007/s00198-010-1524-7
Exercise-Induced splanchnic hypoperfusion results in gut dysfunction in healthy men
Wijck, Kim V., Lenaerts, Kaatje, Van Loon, Luc, Peters, Wilbert H. M., Buurman, Wim A. and Dejong, Cornelis H. C.. (2011) Exercise-Induced splanchnic hypoperfusion results in gut dysfunction in healthy men. PLoS ONE. 6(7), pp. 1 - 10. https://doi.org/10.1371/journal.pone.0022366
Official positions for FRAX® Bone Mineral Density and FRAX® Simplification. From Joint official positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX
Lewiecki, E. Michael, Compston, Juliet E., Miller, Paul D., Adachi, Jonathan D., Adams, Judith E., Leslie, William D., Kanis, John A., Moayyeri, Alireza, Adler, Robert A., Hans, Didier B., Kendler, David L., Diez-Perez, Adolfo, Krieg, Marc-Antoine, Masri, Basel K., Lorenc, Roman R., Bauer, Douglas C., Blake, Glen M., Josse, Robert G., Clark, Patricia and Khan, Aliya A.. (2011) Official positions for FRAX® Bone Mineral Density and FRAX® Simplification. From Joint official positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX. Journal of Clinical Densitometry. 14(3), pp. 226 - 236. https://doi.org/10.1016/j.jocd.2011.05.017
Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis
Rizzoli, Rene, Reginster, Jean-Yves, Boonen, Steven, Bréart, Gérard, Diez-Perez, Adolfo, Felsenberg, Dieter, Kaufman, Jean-Marc, Kanis, John A. and Cooper, Cyrus. (2011) Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis. Calcified Tissue International. 89(2), pp. 91 - 104. https://doi.org/10.1007/s00223-011-9499-8
Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance
Looker, A. C., Dawson-Hughes, B., Tosteson, Anna N. A., Johansson, Helena, Kanis, John A. and Melton, Lisa J.. (2011) Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance. Osteoporosis International. 22(2), pp. 541 - 549. https://doi.org/10.1007/s00198-010-1288-0
Spine-hip discordance and fracture risk assessment: A physician-friendly FRAX enhancement
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011) Spine-hip discordance and fracture risk assessment: A physician-friendly FRAX enhancement. Osteoporosis International. 22(3), pp. 839 - 847. https://doi.org/10.1007/s00198-010-1461-5
Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden
Johansson, Helena, Oden, Anders, Kanis, John A., McCloskey, Eugene V., Lorentzon, Mattias, Ljunggren, Östen, Karlsson, Magnus K., Orwoll, E., Tivesten, A., Ohlsson, Claes and Mellström, Dan. (2011) Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden. Osteoporosis International. 22(5), pp. 1411 - 1418. https://doi.org/10.1007/s00198-010-1331-1
Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards
Vasikaran, Samuel, Eastell, Richard, Bruyere, O., Foldes, A. J., Garnero, P., Griesmacher, Andrea, McClung, Michael R., Morris, Howard A., Silverman, S., Trenti, Tommaso, Wahl, D. A., Cooper, Cyrus and Kanis, John A.. (2011) Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards. Osteoporosis International. 22(2), pp. 391 - 420. https://doi.org/10.1007/s00198-010-1501-1
Milk intake and risk of hip fracture in men and women: A meta-analysis of prospective cohort studies
Bischoff-Ferrari, Heike A., Dawson-Hughes, Bess, Baron, John A., Kanis, John A., Orav, Endel J., Staehelin, Hannes B., Kiel, Douglas P., Burckhardt, Peter, Henschkowski, Jana, Spiegelman, Donna, Li, Ruifeng, Wong, John B., Feskanich, Diane and Willett, Walter C.. (2011) Milk intake and risk of hip fracture in men and women: A meta-analysis of prospective cohort studies. Journal of Bone and Mineral Research. 26(4), pp. 833 - 839. https://doi.org/10.1002/jbmr.279
Secular trends in the incidence of hip and other osteoporotic fractures
Cooper, Cyrus, Cole, Z. A., Holroyd, C. R., Earl, S. C., Harvey, Nicholas C., Dennison, Elaine M., Melton, Lisa, Cummings, Steven R. and Kanis, John A.. (2011) Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporosis International. 22(5), pp. 1277 - 1288. https://doi.org/10.1007/s00198-011-1601-6
A FRAX® model for the assessment of fracture probability in Belgium
Johansson, Helena, Kanis, John, McCloskey, Eugene, Oden, Anders, Devogelaer, J. P., Kaufman, J-M, Neuprez, A., Hiligsmann, Mickaël, Bruyère, O. and Reginster, Jean Yves. (2011) A FRAX® model for the assessment of fracture probability in Belgium. Osteoporosis International. 22(2), pp. 453 - 461. https://doi.org/10.1007/s00198-010-1218-1
International osteoporosis foundation and international federation of clinical chemistry and laboratory medicine position on bone marker standards in osteoporosis
Vasikaran, Samuel, Cooper, Cyrus, Eastell, Richard, Griesmacher, Andrea, Morris, Howard A., Trenti, Tommaso and Kanis, John A.. (2011) International osteoporosis foundation and international federation of clinical chemistry and laboratory medicine position on bone marker standards in osteoporosis. Clinical Chemistry and Laboratory Medicine. 49(8), pp. 1271 - 1274. https://doi.org/10.1515/CCLM.2011.602
Cost-effectiveness of bazedoxifene incorporating the FRAX® algorithm in a European perspective
Borgström, F., Ström, O., Kleman, M., McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John A.. (2011) Cost-effectiveness of bazedoxifene incorporating the FRAX® algorithm in a European perspective. Osteoporosis International. 22(3), pp. 955 - 965. https://doi.org/10.1007/s00198-010-1291-5
Identifying cost-effective treatment with raloxifene in postmenopausal women using risk algorithms for fractures and invasive breast cancer
Ivergãrd, M., Ström, O., Borgström, F., Burge, R., Tosteson, Anna N. A. and Kanis, John. (2010) Identifying cost-effective treatment with raloxifene in postmenopausal women using risk algorithms for fractures and invasive breast cancer. Bone. 47(5), pp. 966 - 974. https://doi.org/10.1016/j.bone.2010.07.024
The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis
Borgström, F., Ström, O., Coelho, J., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010) The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis. Osteoporosis International. 21(2), pp. 339 - 349. https://doi.org/10.1007/s00198-009-0971-5
Independent clinical validation of a Canadian FRAX tool: Fracture prediction and model calibration
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010) Independent clinical validation of a Canadian FRAX tool: Fracture prediction and model calibration. Journal of Bone and Mineral Research. 25(11), pp. 2350 - 2358. https://doi.org/10.1002/jbmr.123
Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer
McCloskey, Eugene, Paterson, Alexander, Kanis, John, Tähtelä, Rita and Powles, Trevor. (2010) Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer. European Journal of Cancer. 46(3), pp. 558 - 565. https://doi.org/10.1016/j.ejca.2009.12.003
FRAX® and its applications in health economics-Cost-effectiveness and intervention thresholds using bazedoxifene in a Swedish setting as an example
Ström, O., Borgström, F., Kleman, M., McCloskey, Eugene, Oden, Anders, Johansson, Helena and Kanis, John. (2010) FRAX® and its applications in health economics-Cost-effectiveness and intervention thresholds using bazedoxifene in a Swedish setting as an example. Bone. 47(2), pp. 430 - 437. https://doi.org/10.1016/j.bone.2010.05.020
Smoking predicts incident fractures in elderly men: Mr OS Sweden
Jutberger, Hans, Lorentzon, Mattias, Barrett-Connor, Elizabeth, Johansson, Helena, Kanis, John, Ljunggren, Östen, Karlsson, Magnus, Rosengren, Björn E., Redlund-Johnell, Inga, Orwoll, E, Ohlsson, Claes and Mellström, Dan. (2010) Smoking predicts incident fractures in elderly men: Mr OS Sweden. Journal of Bone and Mineral Research. 25(5), pp. 1010 - 1016. https://doi.org/10.1359/jbmr.091112
An evaluation of the NICE guidance for the prevention of osteoporotic fragility fractures in postmenopausal women
Kanis, John, McCloskey, Eugene, Jonsson, Bengt, Cooper, Alun, Ström, O. and Borgström, F.. (2010) An evaluation of the NICE guidance for the prevention of osteoporotic fragility fractures in postmenopausal women. Archives of Osteoporosis. 5(43862), pp. 19 - 48. https://doi.org/10.1007/s11657-010-0045-5
Application of the national osteoporosis foundation guidelines to postmenopausal women and men: The Framingham osteoporosis study
Berry, S. D., Kiel, Douglas P., Donaldson, Meghan G., Cummings, Steven R., Kanis, John, Johansson, Helena and Samelson, E. J.. (2010) Application of the national osteoporosis foundation guidelines to postmenopausal women and men: The Framingham osteoporosis study. Osteoporosis International. 21(1), pp. 53 - 60. https://doi.org/10.1007/s00198-009-1127-3
The need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: A view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Bruyère, O., Kanis, John, Ibar-Abadie, M. E., Alsayed, N., Brandi, Maria Luisa, Burlet, N., Cahall, D., Chines, A., Devogelaer, J. P., Dere, W., Goel, N., Hughes, N., Kaufman, J-M, Korte, S., Mitlak, Bruce, Niese, D., Rizzoli, Rene, Rovati, Lucio C. and Reginster, Jean Yves. (2010) The need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: A view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporosis International. 21(5), pp. 713 - 722. https://doi.org/10.1007/s00198-010-1190-9
Validation of the IOF quality of life questionnaire for patients with wrist fracture
Lips, P., Jameson, Karen A., Bianchi, Maria L., Goemaere, Stefan, Boonen, Steven, Reeve, Jonathan, Stepan, Jan J., Johnell, O., van Schoor, Natasja M., Dennison, Elaine M., Kanis, John and Cooper, Cyrus. (2010) Validation of the IOF quality of life questionnaire for patients with wrist fracture. Osteoporosis International. 21(1), pp. 61 - 70. https://doi.org/10.1007/s00198-009-0946-6
The cost-effectiveness of risedronate in the UK for the management of osteoporosis using the FRAX®
Borgström, F., Ström, O., Coelho, J., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010) The cost-effectiveness of risedronate in the UK for the management of osteoporosis using the FRAX®. Osteoporosis International. 21(3), pp. 495 - 505. https://doi.org/10.1007/s00198-009-0989-8
Nutritional strategies to promote postexercise recovery
Beelen, M, Burke, Louise, Gibala, M and van Loon, Luc. (2010) Nutritional strategies to promote postexercise recovery. International Journal of Sport Nutrition and Exercise Metabolism. 20(6), pp. 515 - 532. https://doi.org/10.1123/ijsnem.20.6.515
The effects of a FRAX® revision for the USA
Kanis, John, Johansson, Helena, Oden, Anders, Dawson-Hughes, Bess, Melton, Lisa and McCloskey, Eugene. (2010) The effects of a FRAX® revision for the USA. Osteoporosis International. 21(1), pp. 35 - 40. https://doi.org/10.1007/s00198-009-1033-8
FRAX assessment of osteoporotic fracture probability in Switzerland
Lippuner, K., Johansson, Helena, Kanis, John and Rizzoli, Rene. (2010) FRAX assessment of osteoporotic fracture probability in Switzerland. Osteoporosis International. 21(3), pp. 381 - 389. https://doi.org/10.1007/s00198-009-0975-1
The potential impact of new National Osteoporosis Foundation guidance on treatment patterns
Dawson-Hughes, Bess, Looker, A. C., Tosteson, Anna N. A., Johansson, Helena, Kanis, John and Melton, Lisa. (2010) The potential impact of new National Osteoporosis Foundation guidance on treatment patterns. Osteoporosis International. 21(1), pp. 41 - 52. https://doi.org/10.1007/s00198-009-1034-7
A meta-analysis of the efficacy of raloxifene on all clinical and vertebral fractures and its dependency on FRAX®
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2010) A meta-analysis of the efficacy of raloxifene on all clinical and vertebral fractures and its dependency on FRAX®. Bone. 47(4), pp. 729 - 735. https://doi.org/10.1016/j.bone.2010.06.009
The incidence and risk of hip fracture in Poland
Czerwinski, E., Kanis, John, Trybulec, B., Johansson, Helena, Borowy, P. and Osieleniec, J.. (2009) The incidence and risk of hip fracture in Poland. Osteoporosis International. 20(8), pp. 1363 - 1367. https://doi.org/10.1007/s00198-008-0787-8
BMD, clinical risk factors and their combination for hip fracture prevention
Johansson, Helena, Kanis, John, Oden, Anders, Johnell, O. and McCloskey, Eugene. (2009) BMD, clinical risk factors and their combination for hip fracture prevention. Osteoporosis International. 20(10), pp. 1675 - 1682. https://doi.org/10.1007/s00198-009-0845-x
How to decide who to treat
Kanis, John, McCloskey, Eugene, Johansson, Helena, Ström, O., Borgström, F. and Oden, Anders. (2009) How to decide who to treat. Best Practice and Research: Clinical Rheumatology. 23(6), pp. 711 - 726. https://doi.org/10.1016/j.berh.2009.09.002
FRAX® and its applications to clinical practice
Kanis, John, Oden, Anders, Johansson, Helena, Borgström, F., Ström, O. and McCloskey, Eugene. (2009) FRAX® and its applications to clinical practice. Bone. 44(5), pp. 734 - 743. https://doi.org/10.1016/j.bone.2009.01.373
Can fall risk be incorporated into fracture risk assessment algorithms: A pilot study of responsiveness to clodronate
Kayan, K., Johansson, Helena, Oden, Anders, Vasireddy, S., Pande, K., Orgee, J., Kanis, John and McCloskey, Eugene. (2009) Can fall risk be incorporated into fracture risk assessment algorithms: A pilot study of responsiveness to clodronate. Osteoporosis International. 20(12), pp. 2055 - 2061. https://doi.org/10.1007/s00198-009-0942-x
Approaches to the targeting of treatment for osteoporosis.
Kanis, John, McCloskey, Eugene, Johansson, Helena and Oden, Anders. (2009) Approaches to the targeting of treatment for osteoporosis. Nature Reviews Rheumatology. 5(8), pp. 425 - 431. https://doi.org/10.1038/nrrheum.2009.139
Cost-effectiveness of hormone therapy in the United States
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2009) Cost-effectiveness of hormone therapy in the United States. Journal of Women's Health. 18(10), pp. 1669 - 1677. https://doi.org/10.1089/jwh.2008.1246
An updated systematic review of health state utility values for osteoporosis related conditions
Peasgood, T., Herrmann, K., Kanis, John and Brazier, J. E.. (2009) An updated systematic review of health state utility values for osteoporosis related conditions. Osteoporosis International. 20(6), pp. 853 - 868. https://doi.org/10.1007/s00198-009-0844-y
Assessment of fracture risk
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2009) Assessment of fracture risk. European Journal of Radiology. 71(3), pp. 392 - 397. https://doi.org/10.1007/s11914-011-0093-9
Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women
Lippuner, K., Johansson, Helena, Kanis, John and Rizzoli, Rene. (2009) Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women. Osteoporosis International. 20(7), pp. 1131 - 1140. https://doi.org/10.1007/s00198-008-0779-8
Ten-year fracture probability identifies women who will benefit from clodronate therapy-additional results from a double-blind, placebo-controlled randomised study
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Vasireddy, S., Kayan, K., Pande, K., Jalava, T. and Kanis, John. (2009) Ten-year fracture probability identifies women who will benefit from clodronate therapy-additional results from a double-blind, placebo-controlled randomised study. Osteoporosis International. 20(5), pp. 811 - 817. https://doi.org/10.1007/s00198-008-0786-9
Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK
Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Francis, Roger M., Kanis, John, Marsh, D., McCloskey, Eugene, Reid, David M., Selby, P. and Wilkins, M.. (2009) Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK. Maturitas. 62(2), pp. 105 - 108. https://doi.org/10.1016/j.maturitas.2008.11.022
Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2009) Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®. Bone. 44(6), pp. 1049 - 1054. https://doi.org/10.1016/j.bone.2009.02.014
From relative risk to absolute fracture risk calculation: The FRAX algorithm
McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John. (2009) From relative risk to absolute fracture risk calculation: The FRAX algorithm. Current Osteoporosis Reports. 7(3), pp. 77 - 83. https://doi.org/10.1007/s11914-009-0013-4
Incorporating adherence into health economic modelling of osteoporosis
Ström, O., Borgström, Frederick, Kanis, John and Jönsson, B.. (2009) Incorporating adherence into health economic modelling of osteoporosis. Osteoporosis International. 20(1), pp. 23 - 34. https://doi.org/10.1007/s00198-008-0644-9
Cost-effectiveness of hormone replacement therapy for menopausal symptoms in the UK
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2009) Cost-effectiveness of hormone replacement therapy for menopausal symptoms in the UK. Menopause International. 15(1), pp. 19 - 25. https://doi.org/10.1258/mi.2009.009004
Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores
Tsang, S. W. Y., Kung, Annie Wai Chee, Kanis, John, Johansson, Helena and Oden, Anders. (2009) Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores. Osteoporosis International. 20(11), pp. 1939 - 1945. https://doi.org/10.1007/s00198-009-0906-1
Assessment of the 10-year probability of osteoporotic hip fracture combining clinical risk factors and heel bone ultrasound: The EPISEM prospective cohort of 12,958 elderly women
Hans, Didier, Durosier, Claire, Kanis, John, Johansson, Helena, Schott-Pethelaz, Anne Marie and Krieg, Marc Antoine. (2008) Assessment of the 10-year probability of osteoporotic hip fracture combining clinical risk factors and heel bone ultrasound: The EPISEM prospective cohort of 12,958 elderly women. Journal of Bone and Mineral Research. 23(7), pp. 1045 - 1051. https://doi.org/10.1359/jbmr.080229
Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX)
Fujiwara, S., Nakamura, T., Orimo, H., Hosoi, T., Gorai, I., Oden, Anders, Johansson, Helena and Kanis, John. (2008) Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX). Osteoporosis International. 19(4), pp. 429 - 435. https://doi.org/10.1007/s00198-007-0544-4
The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden
Zethraeus, N., Ström, O., Borgström, Frederick, Kanis, John and Jönsson, B.. (2008) The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden. Osteoporosis International. 19(6), pp. 819 - 827. https://doi.org/10.1007/s00198-007-0511-0
A reference standard for the description of osteoporosis
Kanis, John, McCloskey, Eugene, Johansson, Helena, Oden, Anders, Melton, Lisa and Khaltaev, Nikolai. (2008) A reference standard for the description of osteoporosis. Bone. 42(3), pp. 467 - 475. https://doi.org/10.1016/j.bone.2007.11.001
Health economics of osteoporosis
Borgström, F. and Kanis, John. (2008) Health economics of osteoporosis. Best Practice and Research: Clinical Endocrinology and Metabolism. 22(5), pp. 885 - 900. https://doi.org/10.1016/j.beem.2008.07.005
Vertebral fracture assessment (VPA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis
McCloskey, Eugene, Vasireddy, S., Threlkeld, Jane, Eastaugh, Joanne, Parry, Ailsa, Bonnet, Nicolas, Beneton, Monique, Kanis, John and Charlesworth, Diane. (2008) Vertebral fracture assessment (VPA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis. Journal of Bone and Mineral Research. 23(10), pp. 1561 - 1568. https://doi.org/10.1359/jbmr.080515
Cost effectiveness of hormone therapy in women at high risks of fracture in Sweden, the US and the UK-Results based on the Women's Health Initiative randomised controlled trial
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2008) Cost effectiveness of hormone therapy in women at high risks of fracture in Sweden, the US and the UK-Results based on the Women's Health Initiative randomised controlled trial. Bone. 42(2), pp. 294 - 306. https://doi.org/10.1016/j.bone.2007.09.059
Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis
Goldhahn, J., Scheele, Wim H., Mitlak, Bruce, Abadie, Eric, Aspenberg, Per, Augat, Peter, Brandi, Maria Luisa, Burlet, N., Chines, A., Delmas, P. D., Dupin-Roger, Isabelle, Ethgen, D., Hanson, Beate, Hartl, Florian, Kanis, John, Kewalramani, Reshma, Laslop, A., Marsh, David, Ormarsdottir, Sif, ... Reginster, Jean Yves. (2008) Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis. Bone. 43(2), pp. 343 - 347. https://doi.org/10.1016/j.bone.2008.04.017
FRAX' and the assessment of fracture probability in men and women from the UK
Kanis, John, Johnell, O., Oden, Anders, Johansson, Helena and McCloskey, Eugene. (2008) FRAX' and the assessment of fracture probability in men and women from the UK. Osteoporosis International. 19(4), pp. 385 - 397. https://doi.org/10.1007/s00198-007-0543-5
Case finding for the management of osteoporosis with FRAX® - Assessment and intervention thresholds for the UK
Kanis, John, McCloskey, Eugene, Johansson, Helena, Ström, O., Borgström, F., Oden, Anders, Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Francis, Roger M., Marsh, D., Reid, David M., Selby, P. and Wilkins, M.. (2008) Case finding for the management of osteoporosis with FRAX® - Assessment and intervention thresholds for the UK. Osteoporosis International. 19(10), pp. 1395 - 1408. https://doi.org/10.1007/s00198-008-0712-1
Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: Results of a double-blind, placebo-controlled randomized study
McCloskey, Eugene, Beneton, Monique, Charlesworth, Diane, Kayan, K., DeTakats, Dominic, Dey, Abhijit, Orgee, J., Ashford, Robert, Forster, Martin, Cliffe, Jennifer, Kersh, Linda, Brazier, J. E., Nichol, Jon, Aropuu, Sakari, Jalava, T. and Kanis, John. (2007) Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: Results of a double-blind, placebo-controlled randomized study. Journal of Bone and Mineral Research. 22(1), pp. 135 - 141. https://doi.org/10.1359/jbmr.061008
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women
Kanis, John, Oden, Anders, Johnell, O., Johansson, Helena, Laet, C. De, Brown, Jacques P., Burckhardt, Peter, Cooper, Cyrus, Christiansen, Claus, Cummings, Steven R., Eisman, John A., Fujiwara, S., Glüer, C. C., Goltzman, David, Hans, Didier, Krieg, Marc Antoine, Lacroix, Andrea Z., McCloskey, Eugene, Mellström, Dan, ... Yoshimura, N.. (2007) The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporosis International. 18(8), pp. 1033 - 1046. https://doi.org/10.1007/s00198-007-0343-y
Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis.
Kanis, John, Stevenson, M., McCloskey, Eugene, Davis, S. and Lloyd-Jones, Myfanwy. (2007) Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis. Health Technology Assessment. 11(7). https://doi.org/10.3310/hta11070
Adherence to treatment of osteoporosis: A need for study
Lekkerkerker, F., Kanis, John, Alsayed, N., Bouvenot, G., Burlet, N., Cahall, D., Chines, A., Delmas, P. D., Dreiser, R. L., Ethgen, D., Hughes, N., Kaufman, J-M, Korte, S., Kreutz, G., Laslop, A., Mitlak, Bruce, Rabenda, V., Rizzoli, Rene, Santora, Arthur C., ... Reginster, Jean Yves. (2007) Adherence to treatment of osteoporosis: A need for study. Osteoporosis International. 18(10), pp. 1311 - 1317. https://doi.org/10.1007/s00198-007-0410-4
The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks
van Staa, T. P., Kanis, John, Geusens, P., Boonen, Annelies, Leufkens, H. G. M. and Cooper, Cyrus. (2007) The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks. Value in Health. 10(5), pp. 348 - 357. https://doi.org/10.1111/j.1524-4733.2007.00188.x
Herbert Andre Fleisch, MD : 22 July 1933-15 May 2007.
Martin, T. John, Christiansen, Claus, Kanis, John and Russell, Graham. (2007) Herbert Andre Fleisch, MD : 22 July 1933-15 May 2007. Osteoporosis International. 18(8), pp. 1019 - 1021. https://doi.org/10.1007/s00198-007-0416-y
Cost-effectiveness of the treatment and prevention of osteoporosis - A review of the literature and a reference model
Zethraeus, N., Borgström, F., Ström, O., Kanis, John and Jönsson, B.. (2007) Cost-effectiveness of the treatment and prevention of osteoporosis - A review of the literature and a reference model. Osteoporosis International. 18(1), pp. 9 - 23. https://doi.org/10.1007/s00198-006-0257-0
Latitude, socioeconomic prosperity, mobile phones and hip fracture risk
Johnell, O., Borgström, F., Jönsson, B. and Kanis, John. (2007) Latitude, socioeconomic prosperity, mobile phones and hip fracture risk. Osteoporosis International. 18(3), pp. 333 - 337. https://doi.org/10.1007/s00198-006-0245-4
Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries - An economic evaluation based on the fracture intervention trial
Ström, O., Borgström, Frederick, Sen, S. S., Boonen, Steven, Haentjens, P., Johnell, O. and Kanis, John. (2007) Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries - An economic evaluation based on the fracture intervention trial. Osteoporosis International. 18(8), pp. 1047 - 1061. https://doi.org/10.1007/s00198-007-0349-5
At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis
Borgström, F., Johnell, O., Kanis, John, Jönsson, B. and Rehnberg, C.. (2006) At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis. Osteoporosis International. 17(10), pp. 1459 - 1471. https://doi.org/10.1007/s00198-006-0107-0
Bone fragility in men - Where are we?
Seeman, Ego, Bianchi, Georges, Khosla, Sundeep, Kanis, John and Orwoll, E. (2006) Bone fragility in men - Where are we? Osteoporosis International. 17(11), pp. 1577 - 1583. https://doi.org/10.1007/s00198-006-0160-8
The cost-effectiveness of risedronate in the treatment of osteoporosis: An international perspective
Borgström, F., Carlsson, Å., Sintonen, H., Boonen, Steven, Haentjens, P., Burge, R., Johnell, O., Jönsson, B. and Kanis, John. (2006) The cost-effectiveness of risedronate in the treatment of osteoporosis: An international perspective. Osteoporosis International. 17(7), pp. 996 - 1007. https://doi.org/10.1007/s00198-006-0094-1
The use of multiple sites for the diagnosis of osteoporosis
Kanis, John, Johnell, O., Oden, Anders, Johansson, Helena, Eisman, John A., Fujiwara, S., Kröger, Heikki, Honkanen, Risto, Melton, Lisa, O'Neill, T. W., Reeve, Jonathan, Silman, A. and Tenenhouse, A.. (2006) The use of multiple sites for the diagnosis of osteoporosis. Osteoporosis International. 17(4), pp. 527 - 534. https://doi.org/10.1007/s00198-005-0014-9
Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]
Powles, Trevor, Paterson, Alexander, McCloskey, Eugene, Schein, Phil, Scheffler, Bobbi, Tidy, Alwynne, Ashley, Sue, Smith, Ian, Ottestad, Lars and Kanis, John. (2006) Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. Breast Cancer Research. 8(2). https://doi.org/10.1186/bcr1384
A simple clinical score for estimating the long-term risk of fracture in post-menopausal women
van Staa, T. P., Geusens, P., Kanis, John, Leufkens, H. G. M., Gehlbach, S. and Cooper, Cyrus. (2006) A simple clinical score for estimating the long-term risk of fracture in post-menopausal women. QJM: An International Journal of Medicine. 99(10), pp. 673 - 682. https://doi.org/10.1093/qjmed/hcl094
An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials
Borgström, F., Jönsson, B., Ström, O. and Kanis, John. (2006) An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials. Osteoporosis International. 17(12), pp. 1781 - 1793. https://doi.org/10.1007/s00198-006-0193-z
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
Johnell, O. and Kanis, John. (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis International. 17(12), pp. 1726 - 1733. https://doi.org/10.1007/s00198-006-0172-4
Preservation of thoracic spine microarchitecture by alendronate: Comparison of histology and microCT
Hordon, L. D., Itoda, M., Shore, P. A., Shore, R. C., Heald, M., Brown, M., Kanis, John, Rodan, G. A. and Aaron, J. E.. (2006) Preservation of thoracic spine microarchitecture by alendronate: Comparison of histology and microCT. Bone. 38(3), pp. 444 - 449. https://doi.org/10.1016/j.bone.2005.09.020