Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia

Journal article


Reginster, Jean Yves, Cooper, Cyrus, Rizzoli, Rene, Kanis, John A., Appelboom, Geoff, Bautmans, Ivan, Bischoff-Ferrari, Heike A., Boers, Maarten, Brandi, Maria Luisa, Bruyère, Olivier, Cherubini, Antonio, Flamion, Bruno, Fielding, Roger A., Gasparik, Andrea Ildiko, Van Loon, Lucas, McCloskey, Eugene, Mitlak, Bruce, Pilotto, Alberto, Reiter-Niesert, Suzanne, ... Cruz-Jentoft, Alfonso J.. (2016). Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clinical and Experimental Research. https://doi.org/10.1007/s40520-015-0517-y
AuthorsReginster, Jean Yves, Cooper, Cyrus, Rizzoli, Rene, Kanis, John A., Appelboom, Geoff, Bautmans, Ivan, Bischoff-Ferrari, Heike A., Boers, Maarten, Brandi, Maria Luisa, Bruyère, Olivier, Cherubini, Antonio, Flamion, Bruno, Fielding, Roger A., Gasparik, Andrea Ildiko, Van Loon, Lucas, McCloskey, Eugene, Mitlak, Bruce, Pilotto, Alberto, Reiter-Niesert, Suzanne, Rolland, Yves, Tsouderos, Yannis, Visser, Marjolein and Cruz-Jentoft, Alfonso J.
Abstract

Purpose Sarcopenia is an age-related muscle condition which is frequently a precursor of frailty, mobility disability and premature death. It has a high prevalence in older populations and presents a considerable social and economic burden. Potential treatments are under development but, as yet, no guidelines support regulatory studies for new drugs to manage sarcopenia. The objective of this position paper is therefore to suggest a set of potential endpoints and target population definitions to stimulate debate and progress within the medico-scientific and regulatory communities. Methods A multidisciplinary expert working group was hosted by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, which reviewed and discussed the recent literature from a perspective of clinical experience and guideline development. Relevant parallels were drawn from the development of definition of osteoporosis as a disease and clinical assessment of pharmaceutical treatments for that indication. Results A case-finding decision tree is briefly reviewed with a discussion of recent prevalence estimations of different relevant threshold values. The selection criteria for patients in regulatory studies are discussed according to the aims of the investigation (sarcopenia prevention or treatment) and the stage of project development. The possible endpoints of such studies are reviewed and a plea is made for the establishment of a core outcome set to be used in all clinical trials of sarcopenia. Conclusions The current lack of guidelines for the assessment of new therapeutic treatments for sarcopenia could potentially hinder the delivery of effective medicines to patients at risk.

KeywordsClinical trials; Sarcopenia; Public health; Preventative health care; Frailty
Year2016
JournalAging Clinical and Experimental Research
Digital Object Identifier (DOI)https://doi.org/10.1007/s40520-015-0517-y
Research GroupMary MacKillop Institute for Health Research
Publisher's version
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Controlled
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Larsson, B. A. M., Johansson, L., Johansson, H., Axelsson, K. F., Harvey, N., Vandenput, L., Magnusson, P., McCloskey, E., Liu, E., Kanis, J. A., Sundh, D. and Lorentzon, M.. (2021). The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density. Osteoporosis International. 32(1), pp. 75-84. https://doi.org/10.1007/s00198-020-05681-w
Fracture risk assessment in celiac disease : A registry-based cohort study
Duerksen, D. R., Lix, L. M., Johansson, H., McCloskey, E. V., Harvey, N. C., Kanis, J. A. and Leslie, W. D.. (2021). Fracture risk assessment in celiac disease : A registry-based cohort study. Osteoporosis International. 32(1), pp. 93-99. https://doi.org/10.1007/s00198-020-05579-7
Fracture prediction from FRAX for Canadian ethnic groups : A registry-based cohort study
Leslie, W. D., Morin, S. N., Lix, L. M., McCloskey, E. V., Johansson, H., Harvey, N. C. and Kanis, J. A.. (2021). Fracture prediction from FRAX for Canadian ethnic groups : A registry-based cohort study. Osteoporosis International. 32(1), pp. 113-122. https://doi.org/10.1007/s00198-020-05594-8
Combining fracture outcomes in phase 3 trials of osteoporosis : An analysis of the effects of denosumab in postmenopausal women
Kanis, J. A., Harvey, N. C., Lorentzon, M., Liu, E., Vandenput, L., McCloskey, E. V. and Johansson, H.. (2021). Combining fracture outcomes in phase 3 trials of osteoporosis : An analysis of the effects of denosumab in postmenopausal women. Osteoporosis International. 32(1), pp. 165-171. https://doi.org/10.1007/s00198-020-05699-0
DO-HEALTH : Vitamin D3 - Omega3 - Home exercise - Healthy aging and longevity trial - Design of a multinational clinical trial on healthy aging among European seniors
Bischoff-Ferrari, Heike A., de Godoi Rezende Costa Molino, Caroline, Rival, Sandrine, Vellas, Bruno, Rizzoli, René, Kressig, Reto W., Kanis, John A., Manson, JoAnn E., Dawson-Hughes, Bess, Orav, Endel J., da Silva, José A. P., Blauth, Michael, Felsenberg, Dieter, Ferrari, Stephen M., Theiler, Robert and Egli, Andreas. (2021). DO-HEALTH : Vitamin D3 - Omega3 - Home exercise - Healthy aging and longevity trial - Design of a multinational clinical trial on healthy aging among European seniors. Contemporary Clinical Trials. 100, p. 106124. https://doi.org/10.1016/j.cct.2020.106124
Machine learning to predict osteoporotic fracture risk from genotypes
Forgetta, Vincenzo, Keller-Baruch, Julyan, Forest, Marie, Durand, Audrey, Bhatnagar, Sahir, Kemp, John, Morris, John A., Kanis, John A., Kiel, Douglas P., McCloskey, Eugene V., Rivadeneira, Fernando, Johannson, Helena, Harvey, Nicholas, Cooper, Cyrus, Evans, David M., Pineau, Joelle, Leslie, William D., Greenwood, Celia M. T. and Richards, J. Brent. (2020). Machine learning to predict osteoporotic fracture risk from genotypes. Cold Spring Harbor Protocols. pp. 1-22. https://doi.org/10.1101/413716
Screening for high hip fracture risk does not impact on falls risk : A post hoc analysis from the SCOOP study
Condurache, C. I., Chiu, S., Chotiyarnwong, P., Johansson, H., Shepstone, L., Lenaghan, E., Cooper, C., Clarke, S., Khioe, R. F. S., Fordham, R., Gittoes, N., Harvey, I., Harvey, N. C., Heawood, A., Holland, R., Howe, A., Kanis, J. A., Marshall, T., O’Neill, T. W., ... the SCOOP Study Team. (2020). Screening for high hip fracture risk does not impact on falls risk : A post hoc analysis from the SCOOP study. Osteoporosis International. 31(3), pp. 457-464. https://doi.org/10.1007/s00198-019-05270-6
Epidemiology of hip fracture and the development of a FRAX model for Uzbekistan
Lesnyak, O., Ismailov, S., Shakirova, M., Alikhanova, N., Zakroyeva, A., Abboskhujaeva, L., Johansson, H., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). Epidemiology of hip fracture and the development of a FRAX model for Uzbekistan. Archives of Osteoporosis. 15(1), p. 119. https://doi.org/10.1007/s11657-020-00792-7
Pharmacologic intervention for prevention of fractures in osteopenic and osteoporotic postmenopausal women : Systemic review and meta-analysis
Wu, Chih-Hsing, Hung, Wei-Chieh, Chang, Ing-Lin, Tsai, Tsung-Ting, Chang, Yin-Fan, McCloskey, Eugene V., Watts, Nelson B., McClung, Michael R., Huang, Chun-Feng, Chen, Chung-Hwan, Wu, Kun-Ling, Tsai, Keh-Sung, Chan, Ding-Cheng, Chen, Jung-Fu, Tu, Shih-Te, Hwang, Jawl-Shan, Xia, Weibo, Matsumoto, Toshio, Chung, Yoon-Sok, ... Chan, Wing P.. (2020). Pharmacologic intervention for prevention of fractures in osteopenic and osteoporotic postmenopausal women : Systemic review and meta-analysis. Bone Reports. 13, p. 100729. https://doi.org/10.1016/j.bonr.2020.100729
Incidence of myocardial infarction and associated mortality varies by latitude and season : Findings from a Swedish Registry Study
Harvey, Nicholas C., Lorentzon, Mattias, Kanis, John A., McCloskey, Eugene and Johansson, Helena. (2020). Incidence of myocardial infarction and associated mortality varies by latitude and season : Findings from a Swedish Registry Study. Journal of Public Health. 42(4), pp. e440-e448. https://doi.org/10.1093/pubmed/fdz131
In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle
Petrick, Heather L., Brunetta, Henver S., Pignanelli, Chris, Nunes, Everson A., van Loon, Luc J. C., Burr, Jamie F. and Holloway, Graham P.. (2020). In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle. The Journal of Physiology. 598(21), pp. 4869-4885. https://doi.org/10.1113/JP280032
Casein ingestion does not increase muscle connective tissue protein synthesis rates
Trommelen, Jorn, Holwerda, Andrew M., Senden, Joan M., Goessens, Joy P. B., Van Kranenburg, Janneau, Gijsen, Annemie P., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Casein ingestion does not increase muscle connective tissue protein synthesis rates. Medicine & Science in Sports & Exercise. 52(9), pp. 1983-1991. https://doi.org/10.1249/MSS.0000000000002337
Effect of vitamin d supplementation, omega-3 fatty acid supplementation or a strength-training exercise program on clinical outcomes in older adults : The DO-HEALTH Randomized Clinical Trial
Bischoff-Ferrari, Heike A., Vellas, Bruno, Rizzoli, René, Kressig, Reto W., da Silva, José A. P., Blauth, Michael, Felson, David T., McCloskey, Eugene V., Watzl, Bernhard, Hofbauer, Lorenz C., Felsenberg, Dieter, Willett, Walter C., Dawson-Hughes, Bess, Manson, JoAnn E., Siebert, Uwe, Theiler, Robert, Staehelin, Hannes B., de Godoi Rezende Costa Molino, Caroline, Chocano-Bedoya, Patricia O., ... for the DO-HEALTH Research Group. (2020). Effect of vitamin d supplementation, omega-3 fatty acid supplementation or a strength-training exercise program on clinical outcomes in older adults : The DO-HEALTH Randomized Clinical Trial. JAMA: Journal of the American Medical Association. 324(18), pp. 1855-1868. https://doi.org/10.1001/jama.2020.16909
Bone densitometry worldwide : A global survey by the ISCD and IOF
Clynes, M. A., Westbury, L. D., Dennison, E. M., Kanis, J., Javaid, M. K., Harvey, N. C., Fujita, M., Cooper, C., Leslie, W. D., Shuhart, C. R., The International Society for Clinical Densitometry (ISCD) and The International Osteoporosis Foundation (IOF). (2020). Bone densitometry worldwide : A global survey by the ISCD and IOF. Osteoporosis International. 31, pp. 1779-1786. https://doi.org/10.1007/s00198-020-05435-8
Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures
John Kanis, Helena Johansson, Nicholas C. Harvey, V. Gudnason, Gunnar Sigurdsson, K. Siggeirsdottir, Mattias Lorentzon, E. Liu, Liesbeth Vandenput and Eugene McCloskey. (2020). Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures. Osteoporosis International. 31(10), pp. 1817-1828. https://doi.org/10.1007/s00198-020-05517-7
FRAX and ethnicity
Kanis, J. A., Cooper, C., Dawson-Hughes, B., Harvey, N. C., Johansson, H., Lorentzon, M., McCloskey, E. V., Reginster, J. Y., Rizzoli, R. and International Osteoporosis Foundation. (2020). FRAX and ethnicity. Osteoporosis International. 31(11), pp. 2063-2067. https://doi.org/10.1007/s00198-020-05631-6
Assessment of cardiovascular safety of anti-osteoporosis drugs
Fuggle, N. R., Cooper, C., Harvey, N. C., Al-Daghri, N., Brandi, M. L., Bruyere, O., Cano, A., Dennison, E. M., Diez-Perez, A., Kaufman, J. M., Palacios, S., Prieto-Alhambra, D., Rozenberg, S., Thomas, T., Tremollieres, F., Rizzoli, R., Kanis, J. A. and Reginster, J. Y.. (2020). Assessment of cardiovascular safety of anti-osteoporosis drugs. Drugs: Education, Prevention and Policy. 80(15), pp. 1537-1552. https://doi.org/10.1007/s40265-020-01364-2
Alternative and complementary therapies in osteoarthritis and cartilage repair
Fuggle, N. R., Cooper, C., Oreffo, R. O. C., Price, A. J., Kaux, J. F., Maheu, E., Cutolo, M., Honvo, G., Conaghan, P. G., Berenbaum, F., Branco, J., Brandi, M. L., Cortet, B., Veronese, N., Kurth, A. A., Matijevic, R., Roth, R., Pelletier, J. P., Martel-Pelletier, J., ... Reginster, J. Y.. (2020). Alternative and complementary therapies in osteoarthritis and cartilage repair. Aging Clinical and Experimental Research. 32(4), pp. 547-560. https://doi.org/10.1007/s40520-020-01515-1
The glycation level of milk protein strongly modulates post-prandial lysine availability in humans
Nyakayiru, Jean, van Lieshout, Glenn A. A., Trommelen, Jorn, van Kranenburg, Janneau, Verdijk, Lex B., Bragt, Marjolijn C. E. and van Loon, Luc J. C.. (2020). The glycation level of milk protein strongly modulates post-prandial lysine availability in humans. British Journal of Nutrition. 123(5), pp. 545-552. https://doi.org/10.1017/S0007114519002927
The concept of skeletal muscle memory : Evidence from animal and human studies
Snijders, Tim, Aussieker, Thorben, Holwerda, Andy, Parise, Gianni, van Loon, Luc J. C. and Verdijk, Lex B.. (2020). The concept of skeletal muscle memory : Evidence from animal and human studies. Acta Physiologica. 229(3), pp. 1-20. https://doi.org/10.1111/apha.13465
Temporal muscle-specific disuse atrophy during one week of leg immobilization
Kilroe, Sean P., Fulford, Jonathan, Jackman, Sarah R., Van Loon, Luc J. C. and Wall, Benjamin T.. (2020). Temporal muscle-specific disuse atrophy during one week of leg immobilization. Medicine & Science in Sports & Exercise. 52(4), pp. 944-954. https://doi.org/10.1249/MSS.0000000000002200
Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial
Parsons, C. M., Harvey, N., Shepstone, L., Kanis, J. A., Lenaghan, E., Clarke, S., Fordham, R., Gittoes, N., Harvey, I., Holland, R., Redmond, N. M., Howe, A., Marshall, T., Peters, T. J., Torgerson, D., O’Neill, T. W., McCloskey, E., Cooper, C., Crabtree, N., ... the Scoop Trial Group. (2020). Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial. Osteoporosis International. 31(1), pp. 67-75. https://doi.org/10.1007/s00198-019-05142-z
Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission
Dirks, Marlou L., Miotto, Paula M., Goossens, Gijs H., Senden, Joan M., Petrick, Heather L., van Kranenburg, Janneau, van Loon, Luc J. C. and Holloway, Graham P.. (2020). Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission. The Journal of Physiology. 598(1), pp. 123-137. https://doi.org/10.1113/JP278920
Risk for hip fracture before and after total knee replacement in Sweden
Vala, C. H., Kärrholm, J., Kanis, J. A., Johansson, H., Sten, S., Sundh, V., Karlsson, M., Lorentzon, M. and Mellström, D.. (2020). Risk for hip fracture before and after total knee replacement in Sweden. Osteoporosis International. 31(5), pp. 887-895. https://doi.org/10.1007/s00198-019-05241-x
Quality of life after fragility fracture in the Russian Federation : Results from the Russian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (ICUROS)
Lesnyak, Olga, Svedbom, Axel, Belova, Ksenia, Dobrovolskaya, Olga, Ershova, Olga, Golubev, Georgij, Grebenshikov, Vyacheslav, Ivanov, Sergej, Kochish, Alexander, Menshikova, Larissa, Nikitinskaya, Oxana, Nurligayanov, Radik, Solodovnikov, Alexander, Toroptsova, Natalia, Varavko, Julia, Zotkin, Eugenij, Borgstrom, Fredrik and Kanis, John A.. (2020). Quality of life after fragility fracture in the Russian Federation : Results from the Russian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (ICUROS). Archives of Osteoporosis. 15(1), pp. 1-9. https://doi.org/10.1007/s11657-020-0699-6
Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans
Gorissen, Stefan H. M., Trommelen, Jorn, Kouw, Imre W. K., Holwerda, Andrew M., Pennings, Bart, Groen, Bart B. L., Wall, Benjamin T., Churchward-Venne, Tyler A., Horstman, Astrid M. H., Koopman, René, Burd, Nicholas A., Fuchs, Cas J., Dirks, Marlou L., Res, Peter T., Senden, Joan M. G., Steijns, Jan M. J. M., de Groot, Lisette C. P. G. M., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans. The Journal of Nutrition. 150(8), pp. 2041-2050. https://doi.org/10.1093/jn/nxaa024
Postexercise cooling impairs muscle protein synthesis rates in recreational athletes
Fuchs, Cas J., Kouw, Imre W. K., Churchward-Venne, Tyler A., Smeets, Joey S. J., Senden, Joan M., Lichtenbelt, Wouter D. van Marken, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. The Journal of Physiology. 598(4), pp. 755-772. https://doi.org/10.1113/JP278996
Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition
Robert B Conley, G. Adib, Robert A. Adler, K. Åkesson, Ivy M Alexander, Kelly C Amenta, Robert D Blank, William Timothy Brox, Emily E Carmody, Karen Chapman-Novakofski, Bart Clarke, Kathleen M Cody, Cyrus Cooper, Carolyn J Crandall, Douglas R Dirschl, Thomas J Eagen, Ann L Elderkin, Masaki Fujita, S L Greenspan, ... Douglas P. Kiel. (2020). Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. Journal of Bone and Mineral Research. 35(1), pp. 36-52. https://doi.org/10.1002/jbmr.3877
Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise
Ian Rollo, Javier T. Gonzalez, Cas J. Fuchs, Lucas Van Loon and Clyde Williams. (2020). Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise. Sports Medicine. 50(11), pp. 1863-1871. https://doi.org/10.1007/s40279-020-01343-3
PRESENT 2020: Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials
James A. Betts, Javier T. Gonzalez, Louise Burke, Graeme L. Close, Ina Garthe, Lewis J James, Asker E Jeukendrup, James P. Morton, David C Nieman, Peter Peeling, Stuart M Phillips, Trent Stellingwerff, Lucas Van Loon, Clyde Williams, Kathleen Woolf, Ronald J. Maughan and Greg Atkinson. (2020). PRESENT 2020: Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials. International Journal of Sport Nutrition and Exercise Metabolism. 30(1), pp. 2-13. https://doi.org/10.1123/ijsnem.2019-0326
Loss in DXA-estimated total body lean mass but not fat mass predicts incident major osteoporotic fracture and hip fracture independently from FRAX : A registry-based cohort study
Leslie, William D., Schousboe, John T., Morin, Suzanne N., Martineau, Patrick, Lix, Lisa M., Johansson, Helena, McCloskey, Eugene V., Harvey, Nicholas C. and Kanis, John A.. (2020). Loss in DXA-estimated total body lean mass but not fat mass predicts incident major osteoporotic fracture and hip fracture independently from FRAX : A registry-based cohort study. Archives of Osteoporosis. 15, pp. 1-7. https://doi.org/10.1007/s11657-020-00773-w
Long-term cost-effectiveness of screening for fracture risk in a UK primary care setting : The SCOOP Study
Söreskog, E., Borgström, F., Shepstone, L., Clarke, S., Cooper, C., Harvey, I., Harvey, N. C., Howe, A., Johansson, H., Marshall, T., O’Neill, T. W., Peters, T. J., Redmond, N. M., Turner, D., Holland, R., McCloskey, E., Kanis, J. A., Heawood, A., Crabtree, N., ... SCOOP Study Team. (2020). Long-term cost-effectiveness of screening for fracture risk in a UK primary care setting : The SCOOP Study. Osteoporosis International. 31, pp. 1499-1506. https://doi.org/10.1007/s00198-020-05372-6
Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool
Henver S Brunetta, Andrew M Holwerda, Luc Van Loon and Graham P Holloway. (2020). Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool. Journal of Science in Sport and Exercise. 2, pp. 15-24. https://doi.org/10.1007/s42978-019-00037-1
Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?
Serge Rozenberg, Nasser M Al-Daghri, M. Aubertin-Leheudre, Maria Luisa Brandi, A. Cano, Peter Collins, C. Cooper, A. R. Genazzani, T. Hillard, John Kanis, J. -M. Kaufman, I. Lambrinoudaki, A. Laslop, Eugene McCloskey, Santiago Palacios, D. Prieto-Alhambra, Jean Yves Reginster, Rene Rizzoli, Giuseppe Rosano, ... Nicholas C. Harvey. (2020). Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis? Osteoporosis International. 31(12), pp. 2271-2286. https://doi.org/10.1007/s00198-020-05497-8
Impact of whole dairy matrix on musculoskeletal health and aging–current knowledge and research gaps
N.R.W. Geiker, C. Mølgaard, S. Iuliano, R. Rizzoli, Y. Manios, L.J.C. van Loon, J.-M. Lecerf, G. Moschonis, J.-Y. Reginster, I. Givens and A. Astrup. (2020). Impact of whole dairy matrix on musculoskeletal health and aging–current knowledge and research gaps. Osteoporosis International. 31(4), pp. 601-615. https://doi.org/10.1007/s00198-019-05229-7
Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest
Gonzalez, Javier T., Dirks, Marlou L., Holwerda, Andrew M., Kouw, Imre W. K. and van Loon, Luc J. C.. (2020). Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest. European Journal of Applied Physiology. 120, pp. 2083-2094. https://doi.org/10.1007/s00421-020-04431-4
Increased risk for hip fracture after death of a spouse - further support for bereavement frailty?
Vala, C. H., Lorentzon, M., Sundh, V., Johansson, H., Lewerin, C., Sten, S., Karlsson, M., Ohlsson, C., Johansson, B., Kanis, J. A. and Mellström, D.. (2020). Increased risk for hip fracture after death of a spouse - further support for bereavement frailty? Osteoporosis International. 31, pp. 485-492. https://doi.org/10.1007/s00198-019-05242-w
Impact of exercise-nutritional state interactions in patients with type 2 diabetes
Verboven, Kenneth, Wens, Inez, Vandenabeele, Frank, Stevens, An, Celie, Bert, Lapauw, Bruno, Dendale, Paul, van Loon, Luc J. C., Calders, Patrick and Hansen, Dominique. (2020). Impact of exercise-nutritional state interactions in patients with type 2 diabetes. Medicine and Science in Sports and Exercise. 52(3), pp. 720-728. https://doi.org/10.1249/MSS.0000000000002165
Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review
Jean Nyakayiru, Luc Van Loon and Lex B. Verdijk. (2020). Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review. Free Radical Biology & Medicine. 152, pp. 295-300. https://doi.org/10.1016/j.freeradbiomed.2020.03.025
Hot-water immersion does not increase post-prandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males
Fuchs, Cas J., Smeets, Joey S. J., Senden, Joan M., Zorenc, Antoine H., Goessens, Joy P. B., van Marken Lichtenbelt, Wouter D., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Hot-water immersion does not increase post-prandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males. Journal of Applied Physiology. 128(4), pp. 1012-1022. https://doi.org/10.1152/japplphysiol.00836.2019
Harmonization of commercial assays for PINP ; the way forward
Vasikaran, S. D., Bhattoa, H. P., Eastell, R., Heijboer, A. C., Jørgensen, N. R., Makris, K., Ulmer, C., Kanis, J. A., Cooper, C., Silverman, S. and Cavalier, E.. (2020). Harmonization of commercial assays for PINP ; the way forward. Osteoporosis International. 31, pp. 409-412. https://doi.org/10.1007/s00198-020-05310-6
Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
John Kanis, Nicholas C. Harvey, Eugene McCloskey, Olivier Bruyere, N. Veronese, Mattias Lorentzon, C. Cooper, Rene Rizzoli, G. Adib, Nasser M. Al-Daghri, C. Campusano, Manju Chandran, Bess Dawson-Hughes, M. K. Javaid, F. Jiwa, Helena Johansson, J K Lee, Enwu Liu, D Messina, ... Jean Yves Reginster. (2020). Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporosis International. 31, pp. 1-12. https://doi.org/10.1007/s00198-019-05176-3
Fragility fractures in Europe : Burden, management and opportunities 
Borgström, Fredrik, Karlsson, Linda, Ortsäter, Gustav, Norton, Nicolas, Halbout, Philippe, Cooper, Cyrus, Lorentzon, Mattias, McCloskey, Eugene V., Harvey, Nicholas C., Javaid, Muhamamd K., Kanis, John A. and International Osteoporosis Foundation. (2020). Fragility fractures in Europe : Burden, management and opportunities . Archives of Osteoporosis. 15(59), pp. 1-21. https://doi.org/10.1007/s11657-020-0706-y
Fracture risk following high-trauma versus low-trauma fracture : A registry-based cohort study
Leslie, W. D., Schousboe, J. T., Morin, S. N., Martineau, P., Lix, L. M., Johansson, H., McCloskey, E. V., Harvey, N. C. and Kanis, J. A.. (2020). Fracture risk following high-trauma versus low-trauma fracture : A registry-based cohort study. Osteoporosis International. 31, pp. 1059-1067. https://doi.org/10.1007/s00198-019-05274-2
European Biological Variation Study (EuBIVAS) : Within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptide of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein - A cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism
Cavalier, E., Lukas, P., Bottani, M., Aarsand, A. K., Ceriotti, F., Coşkun, A., Díaz-Garzón, J., Fernàndez-Calle, P., Guerra, E., Locatelli, M., Sandberg, S., Carobene, A., European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation and IOF-IFCC Committee on Bone Metabolism, Cooper, C. and Kanis, J. A.. (2020). European Biological Variation Study (EuBIVAS) : Within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptide of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein - A cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism. Osteoporosis International. 31, pp. 1461-1470. https://doi.org/10.1007/s00198-020-05362-8
Estimation of long-term efficacy of denosumab treatment in postmenopausal women with osteoporosis : A FRAX- and virtual twin-based post hoc analysis from FREEDOM and FREEDOM Extension trials
Siris, Ethel, McDermott, Michele, Pannacciulli, Nicola, Miller, Paul D., Lewiecki, E. Michael, Chapurlat, Roland, Jódar-Gimeno, Esteban, Huang, Shuang and Kanis, John A.. (2020). Estimation of long-term efficacy of denosumab treatment in postmenopausal women with osteoporosis : A FRAX- and virtual twin-based post hoc analysis from FREEDOM and FREEDOM Extension trials. JBMR Plus. 4(4), pp. 1-5. https://doi.org/10.1002/jbm4.10348
Epidemiology of osteoporotic fracture in Moldova and development of a country-specific FRAX model
Zakroyeva, Alla, Lesnyak, Olga, Cazac, Victor, Groppa, Liliana, Russu, Eugen, Chislari, Lia, Rotaru, Larisa, Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene, Lorentzon, Mattis and Kanis, John. (2020). Epidemiology of osteoporotic fracture in Moldova and development of a country-specific FRAX model. Archives of Osteoporosis. 15, pp. 1-8. https://doi.org/10.1007/s11657-019-0669-z
Epidemiology of osteoporotic fracture in Kazakhstan and development of a country specific FRAX model
Issayeva, S., Lesnyak, O., Zakroyeva, A., Issayeva, B., Dilmanova, D., Johansson, H., Liu, E., Lorentzon, M., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). Epidemiology of osteoporotic fracture in Kazakhstan and development of a country specific FRAX model. Archives of Osteoporosis. 15, pp. 1-8. https://doi.org/10.1007/s11657-020-0701-3
Endurance-type exercise increases bulk and individual mitochondrial protein synthesis rates in rats
Holwerda, Andrew M., Bouwman, Freek G., Nabben, Miranda, Wang, Ping, van Kranenburg, Janneau, Gijsen, Annemie P., Burniston, Jatin G., Mariman, Edwin C. M. and van Loon, Luc J. C.. (2020). Endurance-type exercise increases bulk and individual mitochondrial protein synthesis rates in rats. International Journal of Sport Nutrition and Exercise Metabolism. 30(2), pp. 153-164. https://doi.org/10.1123/ijsnem.2019-0281
End-stage renal disease patients lose a substantial amount of amino acids during hemodialysis
Hendriks, Floris K., Smeets, Joey S. J., Broers, Natascha J. H., van Kranenburg, Janneau M. X., van der Sande, Frank M., Kooman, Jeroen P. and van Loon, Luc J. C.. (2020). End-stage renal disease patients lose a substantial amount of amino acids during hemodialysis. The Journal of Nutrition. 150(5), pp. 1160-1166. https://doi.org/10.1093/jn/nxaa010
During hospitalization, older patients at risk for malnutrition consume <0.65 grams of protein per kilogram body weight per day
Weijzen, Michelle E. G., Kouw, Imre W. K., Geerlings, Phil, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). During hospitalization, older patients at risk for malnutrition consume <0.65 grams of protein per kilogram body weight per day. Nutrition in Clinical Practice. 35(4), pp. 655-663. https://doi.org/10.1002/ncp.10542
Dose-response effects of dietary protein on muscle protein synthesis during recovery from endurance exercise in young men : A double-blind randomized trial
Churchward-Venne, Tyler A., Pinckaers, Philippe J. M., Smeets, Joey S. J., Betz, Milan W., Senden, Joan M., Goessens, Joy P. B., Gijsen, Annemie P., Rollo, Ian, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Dose-response effects of dietary protein on muscle protein synthesis during recovery from endurance exercise in young men : A double-blind randomized trial. American Journal of Clinical Nutrition. 112(2), pp. 303-317. https://doi.org/10.1093/ajcn/nqaa073
Development of a polygenic risk score to improve screening for fracture risk : A genetic risk prediction study
Forgetta, Vincenzo, Keller-Baruch, Julyan, Forest, Marie, Durand, Audrey, Bhatnagar, Sahir, Kemp, John P., Nethander, Maria, Evans, Daniel, Morris, John A., Kiel, Douglas P., Rivadeneira, Fernando, Johansson, Helena, Harvey, Nicholas C., Mellström, Dan, Karlsson, Magnus, Cooper, Cyrus, Evans, David M., Clarke, Robert, Kanis, John, A., ... Richards, J. Brent. (2020). Development of a polygenic risk score to improve screening for fracture risk : A genetic risk prediction study. PLoS Medicine. 17(7), pp. 1-19. https://doi.org/10.1371/journal.pmed.1003152
Casein protein processing strongly modulates post-prandial plasma amino acid responses in vivo in humans
Trommelen, Jorn, Weijzen, Michelle E. G., van Kranenburg, Janneau, Ganzevles, Renate A., Beelen, Milou, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Casein protein processing strongly modulates post-prandial plasma amino acid responses in vivo in humans. Nutrients. 12(8), pp. 1-12. https://doi.org/10.3390/nu12082299
A surrogate FRAX model for the Kyrgyz Republic
Lesnyak, O., Zakroyeva, A., Lobanchenko, O., Johansson, H., Liu, E., Lorentzon, M., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). A surrogate FRAX model for the Kyrgyz Republic. Archives of Osteoporosis. 15, pp. 1-5. https://doi.org/10.1007/s11657-020-00743-2
A nitrate-rich vegetable intervention elevates plasma nitrate and nitrite concentrations and reduces blood pressure in healthy young adults
van der Avoort, Cindy M. T., Jonvik, Kristin L., Nyakayiru, Jean, van Loon, Luc J. C., Hopman, Maria T. E. and Verdijk, Lex B.. (2020). A nitrate-rich vegetable intervention elevates plasma nitrate and nitrite concentrations and reduces blood pressure in healthy young adults. Journal of the Academy of Nutrition and Dietetics. 120(8), pp. 1305-1317. https://doi.org/10.1016/j.jand.2020.02.014
Epidemiology of hip fractures in Bulgaria: Development of a country-specific FRAX model
Kirilova, E., Johansson, H., Kirilov, N., Vladeva, S., Petranova, T., Kolarov, Z., Liu, E., Lorentzon, M., Vandenput, L., Harvey, N. C., McCloskey, E. and Kanis, John A.. (2020). Epidemiology of hip fractures in Bulgaria: Development of a country-specific FRAX model. Archives of Osteoporosis. 15(28), pp. 1 - 7. https://doi.org/10.1007/s11657-020-0710-2
A decade of FRAX: How has it changed the management of osteoporosis?
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Liu, Enwu, Vandenput, Liesbeth, Lorentzon, Mattias, Leslie, William D. and McCloskey, Eugene V.. (2020). A decade of FRAX: How has it changed the management of osteoporosis? Aging Clinical and Experimental Research. 32(2), pp. 187 - 196. https://doi.org/10.1007/s40520-019-01432-y
Use of age-dependent FRAX-based intervention thresholds for Singapore
Kanis, John A., Chandran, Manju, Chionh, Siok Bee, Ganeson, Ganga, Harvey, Nicholas C., Koh, Woon-Puay, Kwok, Timothy, Lau, Tang Ching, Liu, Enwu, Lorentzon, Mattias, McCloskey, Eugene V., Tan, Kelvin Bryan, Vandenput, Liesbeth and Johansson, Helena. (2020). Use of age-dependent FRAX-based intervention thresholds for Singapore. Archives of Osteoporosis. 15, pp. 1 - 10. https://doi.org/10.1007/s11657-020-00782-9
Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates
Kilroe, Sean P., Fulford, Jonathan, Holwerda, Andrew M., Jackman, Sarah R., Lee, Benjamin P., Gijsen, Annemie P., van Loon, Luc J. C. and Wall, Benjamin T.. (2019). Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates. American Journal of Physiology - Endocrinology and Metabolism. 318(2), pp. E117-E130. https://doi.org/10.1152/ajpendo.00360.2019
The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation
Jorn Trommelen, Andrew M. Holwerda, Jean Nyakayiru, Stefan H M Gorissen, Olav Rooyackers, Nicholas A Burd, Yves Boirie and Luc J. C. Van Loon. (2019). The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation. American Journal of Physiology - Endocrinology and Metabolism. 317(3), pp. 433-434. https://doi.org/10.1152/ajpendo.00155.2019
Fructose co-ingestion to increase carbohydrate availability in athletes
Cas J. Fuchs, Javier T. Gonzalez and Luc J. C. Van Loon. (2019). Fructose co-ingestion to increase carbohydrate availability in athletes. The Journal of Physiology. 597(14), pp. 3549-3560. https://doi.org/10.1113/JP277116
East meets West: current practices and policies in the management of musculoskeletal aging
Weibo Xia, Cyrus Cooper, Mei Li, Ling Xu, Rene Rizzoli, Mei Zhu, Hua Lin, John Beard, Yue Ding, Wei Yu, Etienne Cavalier, Zhenlin Zhang, John Kanis, Qun Cheng, Quimei Wang and Jean-Yves Reginster. (2019). East meets West: current practices and policies in the management of musculoskeletal aging. Aging Clinical and Experimental Research. 31(10), pp. 1351-1373. https://doi.org/10.1007/s40520-019-01282-8
Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis
Floris K. Hendriks, Joey S J Smeets, Frank M van der Sande, Jeroen P Kooman and Lucas Van Loon. (2019). Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis. Nutrients. 11(12), pp. 1-13. https://doi.org/10.3390/nu11122972
Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF)
Mickaël Hiligsmann, D Cornelissen, B Vrijens, Bo Abrahamsen, Nasser M Al-Daghri, Emmanuel Biver, Maria Luisa Brandi, Olivier Bruyere, N. Burlet, C. Cooper, Bernard Cortet, Elaine M. Dennison, Aldolfo Diez-Perez, Andrea Ildiko Gasparik, A Grosso, P Hadji, P. Halbout, John Kanis, J -M Kaufman, ... Jean Yves Reginster. (2019). Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF). Osteoporosis International. 30(11), pp. 2155-2165. https://doi.org/10.1007/s00198-019-05104-5
Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis
Mattias Lorentzon, Jaime Branco, Maria Luisa Brandi, Olivier Bruyere, Roland D Chapurlat, Cyrus Cooper, Bernard Cortet, Aldolfo Diez-Perez, Serge L Ferrari, Andrea Ildiko Gasparik, Markus Herrmann, N. R. Jorgensen, John Kanis, Jean-Marc Kaufman, A. Laslop, Medea Locquet, Radmila Matijevic, Eugene McCloskey, Salvatore Minisola, ... Etienne Cavalier. (2019). Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis. Advances in Therapy. 36(10), pp. 2811-2824. https://doi.org/10.1007/s12325-019-01063-9
The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise
Jorn Trommelen, Milan W Betz and Luc Van Loon. (2019). The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise. Sports Medicine. 49(2), pp. 185-197. https://doi.org/10.1007/s40279-019-01053-5
Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention
Colleen F. McKenna, Amadeo F. Salvador, Floris K. Hendriks, Alana P. Y. Harris, Luc J. C. Van Loon and Nicholas A. Burd. (2019). Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention. Seminars in Dialysis. 32(4), pp. 379-385. https://doi.org/10.1111/sdi.12805
Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients
Irene Fleur Kramer, Taco J. Blokhuis, Lex B. Verdijk, Luc Van Loon and Martijn Poeze. (2019). Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients. Nutrition Reviews. 77(4), pp. 254-266. https://doi.org/10.1093/nutrit/nuy055
Executive summary of European guidance for the diagnosis and management of osteoporosis in postmenopausal women
J. A. Kanis, C. Cooper, R. Rizzoli and J.-Y. Reginster. (2019). Executive summary of European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Aging Clinical and Experimental Research. 31(1), pp. 15-17. https://doi.org/10.1007/s40520-018-1109-4
Recommendations for the conduct of economic evaluations in osteoporosis: outcomes of an experts’ consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation
M. Hiligsmann, J.-Y. Reginster, A.N.A. Tosteson, S.V. Bukata, K.G. Saag, D.T. Gold, P. Halbout, F. Jiwa, E.M. Lewiecki, D. Pinto, J.D. Adachi, N. Al-Daghri, O. Bruyère, M. Chandran, C. Cooper, N.C. Harvey, T.A. Einhorn, J.A. Kanis, D.L. Kendler, ... S. Silverman. (2019). Recommendations for the conduct of economic evaluations in osteoporosis: outcomes of an experts’ consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation. Osteoporosis International. 30(1), pp. 45-57. https://doi.org/10.1007/s00198-018-4744-x
Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
Maarten de Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G. Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Araujo de Carvalho, Mary Barker, Nicola Bedlington, Maria Luisa Brandi, Olivier Bruyère, Nansa Burlet, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, ... Jean-Yves Reginster. (2019). Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Aging Clinical and Experimental Research. 31(7), pp. 905-915. https://doi.org/10.1007/s40520-019-01193-8
Sarcopenia: revised European consensus on definition and diagnosis
Alfonso J. Cruz-Jentoft, Gülistan Bahat, Jürgen Bauer, Yves Boirie, Olivier Bruyère, Tommy Cederholm, Cyrus Cooper, Francesco Landi, Yves Rolland, Avan Aihie Sayer, Stéphane M. Schneider, Cornel C. Sieber, Eva Topinkova, Maurits Vandewoude, Marjolein Visser, Mauro Zamboni, John Kanis, Writing Group For The European Working Group On Sarcopenia In Older People 2 (EWGSOP2) and The Extended Group For EWGSOP2*. (2019). Sarcopenia: revised European consensus on definition and diagnosis. Age and Ageing. 48(1), pp. 16-31. https://doi.org/10.1093/ageing/afy169
Assessment of Muscle Function and Physical Performance in Daily Clinical Practice
Charlotte Beaudart, Yves Rolland, Alfonso J. Cruz-Jentoft, Jürgen M. Bauer, Cornel Sieber, Cyrus Cooper, Nasser Al-Daghri, Islene Araujo de Carvalho, Ivan Bautmans, Roberto Bernabei, Olivier Bruyère, Matteo Cesari, Antonio Cherubini, Bess Dawson-Hughes, John A. Kanis, Jean-Marc Kaufman, Francesco Landi, Stefania Maggi, Eugene McCloskey, ... Roger A. Fielding. (2019). Assessment of Muscle Function and Physical Performance in Daily Clinical Practice. Calcified Tissue International. 105(1), pp. 1-13. https://doi.org/10.1007/s00223-019-00545-w
Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review
Bauer, Jurgen M., Cruz-Jentoft, Alfonso J., Fielding, Roger A., Kanis, John A., Reginster, Jean-Yves, Bruyere, Olivier, Cesari, Matteo, Chapurlat, Roland, Al-Daghri, Nasser, Dennison, Elaine M., Kaufman, Jean-Marc, Landi, Francesco, Laslop, Andrea, Locquet, Medea, Maggi, Stefania, McCloskey, Eugene, Perna, Simone, Rizzoli, Rene, Rolland, Yves, ... Cooper, Cyrus. (2019). Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review. Calcified Tissue International. 105, pp. 109 - 124. https://doi.org/10.1007/s00223-019-00561-w
Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults
Gratza, S. K., Chocano-Bedoya, Patricia O., Orav, E. J., Fischbacher, M., Freystätter, G., Theiler, Robert, Egli, Andreas, Kressig, R. W., Kanis, John A. and Bischoff-Ferrari, Heike A.. (2019). Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults. Osteoporosis International. 30, pp. 2205 - 2215. https://doi.org/10.1007/s00198-019-05110-7
Executive summary of the European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, John A., Cooper, C., Rizzoli, Rene and Reginster, Jean-Yves. (2019). Executive summary of the European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Calcified Tissue International. 104(3), pp. 235 - 238. https://doi.org/10.1007/s00223-018-00512-x
One week of step reduction lowers myofibrillar protein synthesis rates in young men
Shad, Brandon J., Thompson, Janice L., Holwerda, Andrew M., Stocks, Ben, Elhassan, Yasir S., Philp, Andrew, Van Loon, Luc J. C. and Wallis, Gareth A.. (2019). One week of step reduction lowers myofibrillar protein synthesis rates in young men. Medicine and Science in Sports and Exercise. 51(10), pp. 2125 - 2134. https://doi.org/10.1249/MSS.0000000000002034
European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, John A., Cooper, Cyrus, Rizzoli, Rene and Reginster, Jean-Yves. (2019). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 30(1), pp. 3 - 44. https://doi.org/10.1007/s00198-018-4704-5
Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men
Holwerda, Andrew M., Paulussen, Kevin J. M., Overkamp, Maarten, Goessens, Joy P. B., Kramer, Irene-Fleur, Wodzig, Will K. W. H., Verdijk, Lex B., de Groot, Lisette C.P.G.M. and van Loon, Luc J. C.. (2019). Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men. American Journal of Physiology - Endocrinology and Metabolism. 317(3), pp. 473 - 482. https://doi.org/10.1152/ajpendo.00073.2019
Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest
Dirks, Marlou L., Smeets, Joey S. J., Holwerda, Andrew M., Kouw, Imre W. K., Marzuca-Nassr, Gabriel N., Gijsen, Annemie P., Holloway, Graham P., Verdijk, Lex B. and van Loon, Luc J. C.. (2019). Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest. American Journal of Physiology - Endocrinology and Metabolism. 316(3), pp. 536 - 545. https://doi.org/10.1152/ajpendo.00378.2018
Extensive undertreatment of osteoporosis in older Swedish women
Lorentzon, Mattias, Nilsson, A. G., Johansson, Helena, Kanis, John A., Mellström, Dan and Sundh, D.. (2019). Extensive undertreatment of osteoporosis in older Swedish women. Osteoporosis International. 30(6), pp. 1297 - 1305. https://doi.org/10.1007/s00198-019-04872-4
Assessing the risk of osteoporotic fractures: The Ecuadorian FRAX model
Lopez Gavilanez, Enrique, Johansson, Helena, McCloskey, Eugene, Harvey, Nicholas C., Bajana, Angel Segale, Blum, Dennise Marriott, Grijalva, Mario Navarro, Curiel, Manuel Diaz and Kanis, John A.. (2019). Assessing the risk of osteoporotic fractures: The Ecuadorian FRAX model. Archives of Osteoporosis. 14(93), pp. 1 - 8. https://doi.org/10.1007/s11657-019-0644-8
Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse
Kneppers, Anita, Leermakers, Pieter, Pansters, Nicholas, Backx, Evelien, Gosker, Harry, van Loon, Luc, Schols, Annemie, Langen, Ramon and Verdijk, Lex. (2019). Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse. The FASEB Journal. 33(1), pp. 1288 - 1298. https://doi.org/10.1096/fj.201701403RRR
Fracture risk in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Niraula, Saroj, McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C. and Kanis, John A.. (2019). Fracture risk in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study. The Oncologist. 24(11), pp. 1432 - 1438. https://doi.org/10.1634/theoncologist.2019-0149
Fracture prediction from self-reported falls in routine clinical practice: a registry-based cohort study
Leslie, William D., Morin, Suzanne N., Lix, Lisa, Martineau, Patrick, Bryanton, M., McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C. and Kanis, John A.. (2019). Fracture prediction from self-reported falls in routine clinical practice: a registry-based cohort study. Osteoporosis International. 30, pp. 2195 - 2203. https://doi.org/10.1007/s00198-019-05106-3
Appendicular lean mass and fracture risk assessment: Implications for FRAX(R) and sarcopenia
Harvey, Nicholas C., Kanis, John A., Liu, Enwu, Johansson, Helena, Lorentzon, Mattias and McCloskey, Eugene. (2019). Appendicular lean mass and fracture risk assessment: Implications for FRAX(R) and sarcopenia. Osteoporosis International. 30(3), pp. 537 - 539. https://doi.org/10.1007/s00198-019-04904-z
Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men
Vliet, Stephan Van, Beals, Joseph W., Holwerda, Andrew M., Emmons, Russell S., Goessens, Joy P., Paluska, Scott A., Lisio, Michael De, van Loon, Luc J. C. and Burd, Nicholas A.. (2019). Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men. Journal of Applied Physiology. 127(6), pp. 1792 - 1801. https://doi.org/10.1152/japplphysiol.00608.2019
Temporal changes in access to FRAX in Thailand between 2010 and 2018
Chotiyarnwong, Pojchong, Harvey, Nicholas C., Johansson, Helena, Liu, Enwu, Lorentzon, Mattias, Kanis, John A. and McCloskey, Eugene V.. (2019). Temporal changes in access to FRAX in Thailand between 2010 and 2018. Archives of Osteoporosis. 14(1), pp. 1 - 7. https://doi.org/10.1007/s11657-019-0613-2
Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trial
Mason, Shaun A., Rasmussen, Bodil, van Loon, Luc J. C., Salmon, Jo and Wadley, Glenn D.. (2019). Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trial. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics. 21(3), pp. 674 - 682. https://doi.org/10.1111/dom.13571
Effect of abaloparatide on vertebral,nonvertebral, major osteoporotic and clinical fractures in a subset of postmenopausal women at increased risk of fracture by FRAX probability
McCloskey, Eugene V., Fitzpatrick, Lorraine, Hu, M.-Y., Williams, G. and Kanis, John A.. (2019). Effect of abaloparatide on vertebral,nonvertebral, major osteoporotic and clinical fractures in a subset of postmenopausal women at increased risk of fracture by FRAX probability. Archives of Osteoporosis. 14(1), pp. 1 - 7. https://doi.org/10.1007/s11657-019-0564-7
Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2O2 emission rates in human skeletal muscle
Petrick, Heather L., Pignanelli, Christopher, Barbeau, Pierre-Andre, Churchward-Venne, Tyler A., Dennis, Kaitlyn M. J. H., van Loon, Luc J. C., Burr, Jamie F., Goossens, Gijs H. and Holloway, Graham P.. (2019). Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2O2 emission rates in human skeletal muscle. The Journal of Physiology. 597(15), pp. 3985 - 3997. https://doi.org/10.1113/JP277765
The prevention of glucocorticoid-induced osteoporosis in patients with immune thrombocytopenia receiving steroids: A British Society for Haematology Good Practice Paper
Hill, Quentin A., Grainger, John D., Thachil, Jecko, Provan, Drew, Evans, Gillian, Garg, Mamta, Bradbury, Charlotte, Bagot, Catherine, Kanis, John A. and Compston, Juliet E.. (2019). The prevention of glucocorticoid-induced osteoporosis in patients with immune thrombocytopenia receiving steroids: A British Society for Haematology Good Practice Paper. British Journal of Haematology. 185(3), pp. 410 - 417. https://doi.org/10.1111/bjh.15735
Performance of FRAX in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Niraula, Saroj, McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C. and Kanis, John A.. (2019). Performance of FRAX in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study. Journal of Bone and Mineral Research. 34(8), pp. 1428 - 1435. https://doi.org/10.1002/jbmr.3726
Fracture risk following intermission of osteoporosis therapy
Dennison, Elaine M., Cooper, Cyrus, Kanis, John A., Bruyère, O., Silverman, S., McCloskey, Eugene, Abrahamsen, Bo, Prieto-Alhambra, D. and Ferrari, Serge L.. (2019). Fracture risk following intermission of osteoporosis therapy. Osteoporosis International. 30(9), pp. 1733 - 1743. https://doi.org/10.1007/s00198-019-05002-w
FRAX-based intervention and assessment thresholds for osteoporosis in Iran
Khashayar, P., Keshtkar, A., Ostovar, A., Larijani, B., Johansson, Helena, Harvey, Nicholas C., Lorentzon, Mattias, McCloskey, Eugene and Kanis, John A.. (2019). FRAX-based intervention and assessment thresholds for osteoporosis in Iran. Osteoporosis International. 30, pp. 2225 - 2230. https://doi.org/10.1007/s00198-019-05078-4
The Fracture Risk Assessment Tool (FRAX®) predicts fracture risk in patients with chronic kidney disease
Whitlock, Reid H., Leslie, William D., Shaw, James, Rigatto, Claudio, Thorlacius, Laurel, Komenda, Paul, Collister, David, Kanis, John A. and Tangri, Navdeep. (2019). The Fracture Risk Assessment Tool (FRAX®) predicts fracture risk in patients with chronic kidney disease. Kidney International. 95(2), pp. 447 - 454. https://doi.org/10.1016/j.kint.2018.09.022
The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function
Boujemaa, Hajar, Yilmaz, Alaaddin, Robic, Boris, Koppo, Katrien, Claessen, Guido, Frederix, Ines, Dendale, Paul, Völler, Heinz, van Loon, Luc J. C. and Hansen, Dominique. (2019). The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function. Experimental Physiology. 104(6), pp. 855 - 865. https://doi.org/10.1113/EP087407
FRAX: Assessment of Fracture Risk
Kanis, John, McCloskey, Eugene, Harvey, Nicholas C. and Leslie, William D.. (2019). FRAX: Assessment of Fracture Risk. In In J. P. Bilezikian (Ed.). Primer on the metabolic bone diseases and disorders of mineral metabolism pp. 331 - 339 Wiley-Blackwell. https://doi.org/10.1002/9781119266594.ch41
Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men
Holwerda, Andrew M., Paulussen, Kevin J. M., Overkamp, Maarten, Goessens, Joy P. B., Kramer, Irene-Fleur, Wodzig, Will K. W. H., Verdijk, Lex B., de Groot, Lisette C. P. G. M. and Van Loon, Luc. (2019). Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men. In In A. M. Holwerda (Ed.). Dietary protein to support active aging pp. 53 - 73 Maastricht University. https://doi.org/10.26481/dis.20190321ah
A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type i procollagen (PINP): A report from the IFCC-IOF Joint Committee for Bone Metabolism
Cavalier, Etienne, Eastell, Richard, Jørgensen, Niklas Rye, Makris, Konstantinos, Tournis, Symeon, Vasikaran, Samuel, Kanis, John A., Cooper, Cyrus, Pottel, Hans and Morris, Howard A.. (2019). A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type i procollagen (PINP): A report from the IFCC-IOF Joint Committee for Bone Metabolism. Clinical Chemistry and Laboratory Medicine. 57(10), pp. 1546 - 1555. https://doi.org/10.1515/cclm-2019-0174
The effect of beetroot juice supplementation on dynamic apnea and intermittent sprint performance in elite female water polo playres
Jonvik, Kristin L., van Dijk, Jan Willem, Senden, Joan M., van Loon, Luc and Verdijk, Lex B.. (2018). The effect of beetroot juice supplementation on dynamic apnea and intermittent sprint performance in elite female water polo playres. International Journal of Sport Nutrition and Exercise Metabolism. 28(5), pp. 468 - 473. https://doi.org/10.1123/ijsnem.2017-0293
Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle
Holloway, Graham P., Holwerda, Andrew M., Miotto, Paula M., Dirks, Marlou L., Verdijk, Lex B. and Van Loon, Luc. (2018). Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle. Cell Reports. 22(11), pp. 2837 - 2848. https://doi.org/10.1016/j.celrep.2018.02.069
Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men
Holwerda, Andrew M., Paulussen, Kevin J. M., Overkamp, Maarten, Smeets, Joey S. J., Gijsen, Annemie P., Goessens, Joy P. B., Verdijk, Lex B. and Van Loon, Luc. (2018). Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men. Journal of Applied Physiology. 124(1), pp. 66 - 75. https://doi.org/10.1152/japplphysiol.00610.2017
Comparison of methods for improving fracture risk assessment in diabetes: the Manitoba BMD Registry
Leslie, William D., Johansson, Helena, Mccloskey, Eugene V., Harvey, Nicholas C., Kanis, John and Hans, Didier. (2018). Comparison of methods for improving fracture risk assessment in diabetes: the Manitoba BMD Registry. Journal of Bone and Mineral Research. 33(11), pp. 1923 - 1930. https://doi.org/10.1002/jbmr.3538
Understanding osteoporotic pain and its pharmacological treatment: supplementary presentation
Vellucci, R., Terenzi, R., Kanis, John, Kress, H.G., Mediati, R.D., Reginster, Jean Y., Rizzoli, Rene and Brandi, Maria L.. (2018). Understanding osteoporotic pain and its pharmacological treatment: supplementary presentation. Osteoporosis International. 29(9), pp. 2153 - 2154. https://doi.org/10.1007/s00198-018-4536-3
Temporal response of angiogenesis and hypertrophy to resistance training in young men
Holloway, Tanya M., Snijders, Tim, van Kranenburg, Janneau, Van Loon, Luc and Verdijk, Lex B.. (2018). Temporal response of angiogenesis and hypertrophy to resistance training in young men. Medicine and Science in Sports and Exercise. 50(1), pp. 36 - 45. https://doi.org/10.1249/MSS.0000000000001409
Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates
Langer, Henning, Senden, Joan M., Gijsen, Annemie P., Kempa, Stefan, van Loon, Luc and Spuler, Simone. (2018). Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates. Frontiers in Physiology. 9(1220), pp. 1 - 10. https://doi.org/10.3389/fphys.2018.01220
Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET
Smeets, Joey S.J and Van Loon, Luc. (2018). Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET. Brain: a journal of neurology. 141(7), pp. 52 - 52. https://doi.org/10.1093/brain/awy119
Which method of fall ascertainment captures the most falls in prefrail and frail seniors?
Teister, Corina J., Chocano-Bedoya, Patricia O., Orav, Endel J., Dawson-Hughes, Bess, Meyer, Ursina, Meyer, Otto W., Freystaetter, Gregor, Gagesch, Michael, Rizzoli, Rene, Egli, Andreas, Theiler, Robert, Kanis, John A. and Bischoff-Ferrari, Heike A.. (2018). Which method of fall ascertainment captures the most falls in prefrail and frail seniors? American Journal of Epidemiology. 187(10), pp. 2243 - 2251. https://doi.org/10.1093/aje/kwy113
Measuring performance on the healthcare access and quality index for 195 countries and territories and selected subnational locations: a systematic analysis from the global burden of disease study 2016
Fullman, Nancy, Yearwood, Jamal, Abay, Solomon M., Abbafati, Cristiana, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abebe, Zegeye, Abebo, Teshome Abuka, Aboyans, Victor, Abraha, Haftom Niguse, Abreu, Daisy M. X., Abu-Raddad, Laith J., Adane, Akilew Awoke, Adedoyin, Rufus Adesoji, Adetokunboh, Olatunji, Adhikari, Tara Ballav, Afarideh, Mohsen, Afshin, Ashkan, ... Lozano, Rafael. (2018). Measuring performance on the healthcare access and quality index for 195 countries and territories and selected subnational locations: a systematic analysis from the global burden of disease study 2016. The Lancet. 391(10136), pp. 2236 - 2271. https://doi.org/10.1016/S0140-6736(18)30994-2
Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise
Niemeijer, Victor M., Snijders, Tim, Verdijk, Lex B., Van Kranenburg, Janneau, Groen, Bart B.L., Holwerda, Andrew M., Spee, Ruud F., Wijn, Pieter F. F., van Loon, Luc and Kemps, Hareld M.C.. (2018). Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise. Journal of Applied Physiology. 125(4), pp. 1266 - 1276. https://doi.org/10.1152/japplphysiol.00057.2018
Falls predict fractures independently of FRAX probability: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study
Harvey, Nicholas C., Oden, Anders, Orwoll, E., Lapidus, Jodi, Kwok, T., Karlsson, Magnus, Rosengren, Björn E., Ljunggren, Östen, Cooper, Cyrus, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes, Mellström, Dan and Johansson, Helena. (2018). Falls predict fractures independently of FRAX probability: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study. Journal of Bone and Mineral Research. 33(3), pp. 510 - 516. https://doi.org/10.1002/jbmr.3331
Cost-effective but clinically inapproriate: new nice intervention thresholds in osteoporosis (technology appraisal 464)
Harvey, Nicholas C., McCloskey, Eugene, Kanis, John, Compston, J E. and Cooper, Cath. (2018). Cost-effective but clinically inapproriate: new nice intervention thresholds in osteoporosis (technology appraisal 464). Osteoporosis International. 29(7), pp. 1511 - 1513. https://doi.org/10.1007/s00198-018-4505-x
Management of patients with high baseline hip fracture risk by FRAX reduces hip fractures—a post hoc analysis of the scoop study
McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Shepstone, L., Lenaghan, E., Fordham, Ric, Harvey, I., Howe, Amanda, Cooper, Cyrus, Clarke, Shane, Gittoes, Neil, Heawood, A., Holland, R., Marshall, Tarnya, O'Neill, T. W., Peters, T. J., Redmond, Niamh, Torgerson, David and Kanis, John A.. (2018). Management of patients with high baseline hip fracture risk by FRAX reduces hip fractures—a post hoc analysis of the scoop study. Journal of Bone and Mineral Research. 33(6), pp. 1020 - 1026. https://doi.org/10.1002/jbmr.3411
Dose-response effects of supplementation with calcifediol on serum 25-hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults
Vaes, Anouk M.M., Tieland, Michael, de Regt, Margot F., Wittwer, Jonas, van Loon, Luc and de Groot, Lisette C.P.G.M.. (2018). Dose-response effects of supplementation with calcifediol on serum 25-hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults. Clinical Nutrition. 37(3), pp. 808 - 814. https://doi.org/10.1016/j.clnu.2017.03.029
Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET
Smeets, Joey S.J and Van Loon, Luc. (2018). Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET. Brain: a journal of neurology. 141(7), pp. 52 - 52. https://doi.org/10.1093/brain/awy119
Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate
Van der Avoort, Cindy M. T., van Loon, Luc, Hopman, Maria T. and Verdijk, Lex B.. (2018). Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate. European Journal of Clinical Nutrition. 72, pp. 1485 - 1489. https://doi.org/10.1038/s41430-018-0140-z
Epidemiology of hip fracture in Belarus: development of a country-specific FRAX model and its comparison to neighboring country models
Ramanau, H., Chernyanin, I., Rudenka, E., Lesnyak, Olga, Zakroyeva, A., Bilezikian, John P., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene and Kanis, John A.. (2018). Epidemiology of hip fracture in Belarus: development of a country-specific FRAX model and its comparison to neighboring country models. Archives of Osteoporosis. 13(1), pp. 1 - 5. https://doi.org/10.1007/s11657-018-0454-4
Effects of creatine and carbohydrate loading on cycling time trial performance
Tomcik, Kristyen A., Camera, Donny, Bone, Julia L. L., Ross, Meg, Jeacocke, N. A., Tachtsis, Bill, Senden, Joan M., Van Loon, Luc, Hawley, John and Burke, Louise. (2018). Effects of creatine and carbohydrate loading on cycling time trial performance. Medicine and Science in Sports and Exercise. 50(1), pp. 141 - 150. https://doi.org/10.1249/MSS.0000000000001401
IOC consensus statement: dietary supplements and the high-performance athlete0306
Maughan, Ronald J., Burke, Louise, Dvorak, Jiri, Larson-Meyer, D. E., Peeling, Peter, Phillips, Stuart M., Rawson, Eric S., Walsh, Neil P., Garthe, Ina, Geyer, Hans, Meeusen, Romain, Van Loon, Luc, Shirreffs, Susan M., Spriet, Lawrence L., Stuart, Mark, Vernec, Alan, Currell, Kevin, Ali, Vidya M., Budgett, Richard, ... Engebretsen, Lars. (2018). IOC consensus statement: dietary supplements and the high-performance athlete0306. British Journal of Sports Medicine. 52(7), pp. 439 - 455. https://doi.org/10.1136/bjsports-2018-099027
A brief history of FRAX
Kanis, John A., Johansson, Helena, Harvey, Nicholas C. and McCloskey, Eugene V.. (2018). A brief history of FRAX. Archives of Osteoporosis. 13(1), pp. 1 - 16. https://doi.org/10.1007/s11657-018-0510-0
In which patients does lumbar spine trabecular bone score (TBS) have the largest effect?
Martineau, Patrick, Leslie, William D., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene, Hans, Didier and Kanis, John A.. (2018). In which patients does lumbar spine trabecular bone score (TBS) have the largest effect? Bone. 113, pp. 161 - 168. https://doi.org/10.1016/j.bone.2018.05.026
The 2017 dutch physical activity guidelines
Weggemans, Rianne M., Backx, Frank J.G., Borghouts, Lars, Chinapaw, Mai J.M., Hopman, Maria T., Koster, Annemarie, Kremers, Stef, Van Loon, Luc, May, Anne M., Mosterd, Arend, van der Ploeg, Hidde, Takken, Tim, Visser, Marjolein, Wendel-Vos, Wanda and de Geus, Eco J.C.. (2018). The 2017 dutch physical activity guidelines. International Journal of Behavioral Nutrition and Physical Activity. 15(58), pp. 1 - 12. https://doi.org/10.1186/s12966-018-0661-9
Measures of physical performance and muscle strength as predictors of fracture risk independent of FRAX, falls, and aBMD: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study
Harvey, Nicholas C., Oden, Anders, Orwoll, E., Lapidus, Jodi, Kwok, T., Karlsson, Magnus, Rosengren, Björn E., Ribom, Eva, Cooper, Cyrus, Cawthon, Peggy M., Kanis, John A., Ohlsson, Claes, Mellström, Dan, Johansson, Helena and McCloskey, Eugene. (2018). Measures of physical performance and muscle strength as predictors of fracture risk independent of FRAX, falls, and aBMD: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study. Journal of Bone and Mineral Research. 33(12), pp. 2150 - 2157. https://doi.org/10.1002/jbmr.3556
Interventional strategies to combat muscle disuse atrophy in humans: Focus on neuromuscular electrical stimulation and dietary protein
Dirks, Marlou L., Wall, Benjamin T. and van Loon, Luc. (2018). Interventional strategies to combat muscle disuse atrophy in humans: Focus on neuromuscular electrical stimulation and dietary protein. Journal of Applied Physiology. 125(3), pp. 850 - 861. https://doi.org/10.1152/japplphysiol.00985.2016
IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete
Maughan, Ronald J., Burke, Louise, Dvorak, Jiri, Larson-Meyer, D. E., Peeling, Peter, Phillips, Stuart M., Rawson, Eric S., Walsh, Neil P., Garthe, Ina, Geyer, Hans, Meeusen, Romain, Van Loon, Luc, Shirreffs, Susan M., Spriet, Lawrence L., Stuart, Mark, Vernec, Alan, Currell, Kevin, Ali, Vidya M., Budgett, Richard, ... Engebretsen, Lars. (2018). IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete. International Journal of Sport Nutrition and Exercise Metabolism. 28(2), pp. 104 - 125. https://doi.org/10.1123/ijsnem.2018-0020
Assessment of fracture risk
McCloskey, Eugene, Leslie, William D. and Kanis, John. (2018). Assessment of fracture risk. In In N. C. Harvey and C. Cooper (Ed.). Osteoporosis: A lifecourse epidemiology approach to skeletal health pp. 163 - 176 CRC Press. https://doi.org/10.1201/9781351234627
Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score (TBS): The Manitoba BMD registry
Leslie, William D., Shevroja, E., Johansson, Helena, McCloskey, Eugene, Harvey, Nicholas C., Kanis, John A. and Hans, Didier. (2018). Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score (TBS): The Manitoba BMD registry. Osteoporosis International. 29(3), pp. 751 - 758. https://doi.org/10.1007/s00198-018-4405-0
A novel in vitro model for the assessment of postnatal myonuclear accretion
Kneppers, Anita, Verdijk, Lex B., de Theije, Chiel, Corten, Mark, Gielen, Ellis, van Loon, Luc, Schols, Annemie and Langen, Ramon. (2018). A novel in vitro model for the assessment of postnatal myonuclear accretion. Skeletal Muscle. 8(4), pp. 1 - 13. https://doi.org/10.1186/s13395-018-0151-4
Pitfalls in the measurement of muscle mass: A need for a reference standard
Buckinx, Fanny, Landi, Francesco, Cesari, Matteo, Fielding, Roger A., Visser, Marjolein, Engelke, Klaus, Maggi, Stefania, Dennison, Elaine, Al-Daghri, Nasser M., Allepaerts, Sophie, Bauer, Jurgen, Bautmans, Ivan, Brandi, Maria Luisa, Bruyère, Olivier, Cederholm, Tommy, Cerreta, Francesca, Cherubini, Antonio, Cooper, Cyrus, Cruz-Jentoft, Alphonso, ... Kanis, John A.. (2018). Pitfalls in the measurement of muscle mass: A need for a reference standard. Journal of Cachexia, Sarcopenia and Muscle. 9(2), pp. 269 - 278. https://doi.org/10.1002/jcsm.12268
Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers
Johansson, Helena, Vala, C. H., Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene, Kanis, John, Harvey, Nicholas C., Ohlsson, Claes, Lohmander, L. S., Karrholm, J. and Mellstrom, D.. (2018). Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers. Osteoporosis International. 29(3), pp. 741 - 749. https://doi.org/10.1007/s00198-017-4355-y
Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation
Rizzoli, Rene, Biver, Emmanuel, Bonjour, J. P., Coxam, V., Goltzman, D., Kanis, John, Lappe, J., Rejnmark, Lars, Sahni, S., Weaver, C., Weiler, H. and Reginster, J. Y.. (2018). Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation. Osteoporosis International. 29(9), pp. 1933 - 1948. https://doi.org/10.1007/s00198-018-4534-5
Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men
Holwerda, Andrew M., Overkamp, Maarten, Paulussen, Kevin J. M., Smeets, Joey S. J., Van Kranenburg, Janneau, Backx, E. M. P., Gijsen, Annemie P., Goessens, Joy P. B., Verdijk, Lex B. and van Loon, Luc. (2018). Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men. The Journal of Nutrition. 148(11), pp. 1723 - 1732. https://doi.org/10.1093/jn/nxy169
A health economic simulation model for the clinical management of osteoporosis
Jonsson, E., Hansson-Hedblom, A., Ljunggren, Östen, Åkesson, K., Spångeus, A., Kanis, John and Borgström, F.. (2018). A health economic simulation model for the clinical management of osteoporosis. Osteoporosis International. 29(3), pp. 545 - 555. https://doi.org/10.1007/s00198-017-4325-4
Protein content and amino acid composition of commercially available plant-based protein isolates
Gorissen, Stefan H. M., Crombag, Julie J. R., Senden, Joan M., Huub Waterval, W. A., Bierau, Jörgen, Verdijk, Lex B. and van Loon, Luc. (2018). Protein content and amino acid composition of commercially available plant-based protein isolates. Amino Acids. 50(12), pp. 1685 - 1695. https://doi.org/10.1007/s00726-018-2640-5
Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men
Backx, E. M. P., Horstman, Astrid M. H., Marzuca-Nassr, Gabriel N., Van Kranenburg, Janneau, Smeets, Joey S. J., Fuchs, Cas J., Janssen, Anniek A. W., de Groot, Lisette C. P. G. M., Snijders, Tim, Verdijk, Lex B. and van Loon, Luc. (2018). Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men. Nutrients. 10(635), pp. 1 - 12. https://doi.org/10.3390/nu10050635
Application of FRAX to determine the risk of osteoporotic fractures in the Ukrainian population
Povoroznyuk, V. V., Grygorieva, Nataliia V., McCloskey, Eugene, Johansson, Helena and Kanis, John. (2018). Application of FRAX to determine the risk of osteoporotic fractures in the Ukrainian population. International Journal of Osteoporosis and Metabolic Disorders. 11(1), pp. 7 - 13. https://doi.org/10.3923/ijom.2018.7.13
Brain tissue plasticity: protein synthesis rates of the human brain0006
Smeets, Joey S. J., Horstman, Astrid M. H., Schijns, Olaf E. M. G., Dings, Jim T. A., Hoogland, Govert, Gijsen, Annemie P., Goessens, Joy P. K., Bouwman, Freek G., Wodzig, Will K. W. H., Mariman, Edwin C. and Van Loon, Luc. (2018). Brain tissue plasticity: protein synthesis rates of the human brain0006. Brain: a journal of neurology. 141(4), pp. 1122 - 1129. https://doi.org/10.1093/brain/awy015
Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients
Hansen, Dominique, Verboven, Kenneth, van Dijk, Jan Willem, Zorenc, Antoine H., Minten, Lennert, Smeets, Kevin, Verdijk, Lex B. and Van Loon, Luc. (2018). Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients. European Journal of Sport Science. 18(9), pp. 1245 - 1254. https://doi.org/10.1080/17461391.2018.1483428
Characteristics of recurrent fractures
Kanis, John A., Johansson, Helena, Odén, Anders, Harvey, Nicholas C., Gudnason, V., Sanders, Kerrie, Sigurdsson, Gunnar, Siggeirsdottir, K., Fitzpatrick, Lorraine A., Borgström, F. and McCloskey, Eugene. (2018). Characteristics of recurrent fractures. Osteoporosis International. 29(8), pp. 1747 - 1757. https://doi.org/10.1007/s00198-018-4502-0
Understanding osteoporotic pain and its pharmacological treatment
Vellucci, R., Terenzi, R., Kanis, John, Kress, H. G., Mediati, R. D., Reginster, J. Y., Rizzoli, Rene and Brandi, Maria Luisa. (2018). Understanding osteoporotic pain and its pharmacological treatment. Osteoporosis International. 29(7), pp. 1477 - 1491. https://doi.org/10.1007/s00198-018-4476-y
Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats
Monaco, Cynthia, Miotto, Paula M., Huber, Jason S., Van Loon, Luc, Simpson, Jeremy A. and Holloway, Graham P.. (2018). Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315(2), pp. 191 - 204. https://doi.org/10.1152/ajpregu.00275.2017
Health-related quality of life during the first year after a hip fracture: Results of the Mexican arm of the International Cost and Utility Related to Osteoporotic Fractures Study (MexICUROS)
Guirant, L., Carlos, Fernando, Curiel, D., Kanis, John A., Borgström, Frederick, Svedbom, Axel and Clark, Patricia. (2018). Health-related quality of life during the first year after a hip fracture: Results of the Mexican arm of the International Cost and Utility Related to Osteoporotic Fractures Study (MexICUROS). Osteoporosis International. 29(5), pp. 1147 - 1154. https://doi.org/10.1007/s00198-018-4389-9
Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture
Malafarina, Vincenzo, Reginster, J. Y., Cabrerizo, Sonia, Bruyère, Olivier, Kanis, John A., Martinez, J. Alfredo and Zulet, M. Angeles. (2018). Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture. Nutrients. 10(5), pp. 1 - 26. https://doi.org/10.3390/nu10050555
The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease
Beijers, Rosanne J. H. C. G., Huysmans, Stephanie M. D., van de Bool, Coby, Kingma, Boris R. M., Verdijk, Lex B., Van Loon, Luc, Meex, Steven J. R., Gosker, Harry R. and Schols, Annemie M. W. J.. (2018). The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease. Clinical Nutrition. 37(6), pp. 1852 - 1861. https://doi.org/10.1016/j.clnu.2017.10.011
Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes
Jonvik, Kristin L., Nyakayiru, Jean, van Dijk, Jan Willem, Maase, K., Ballak, S. B., Senden, Joan M., van Loon, Luc and Verdijk, Lex B.. (2018). Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes. European Journal of Sport Science. 18(4), pp. 524 - 533. https://doi.org/10.1080/17461391.2018.1433722
Review of the guideline of the American College of Physicians on the treatment of osteoporosis
Kanis, J. A., Cooper, C., Rizzoli, R. and Reginster, J.-Y.. (2018). Review of the guideline of the American College of Physicians on the treatment of osteoporosis. Osteoporosis International. 29(7), pp. 1505 - 1510. https://doi.org/10.1007/s00198-018-4504-y
Does nutrition play a role in the prevention and management of sarcopenia?
Robinson, S. M., Reginster, J. Y., Rizzoli, R., Shaw, S. C., Kanis, J. A., Bautmans, I., Bischoff-Ferrari, H., Bruyère, O., Cesari, M., Dawson-Hughes, B., Fielding, R. A., Kaufman, J. M., Landi, F., Malafarina, Vincenzo, Rolland, Y., van Loon, L. J., Vellas, B., Visser, M. and Cooper, C.. (2018). Does nutrition play a role in the prevention and management of sarcopenia? Clinical Nutrition. 37(4), pp. 1121 - 1132. https://doi.org/10.1016/j.clnu.2017.08.016
Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET
Smeets, Joey S.J. and Van Loon, Luc. (2018). Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[1-11c]-leucine PET. Brain: a journal of neurology. 141(7), pp. 52 - 52. https://doi.org/10.1093/brain/awy119
Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial
Shepstone, L., Lenaghan, E., Cooper, C., Clarke, Shane, Fong-Soe-Khioe, Rebekah, Fordham, R., Gittoes, Neil, Harvey, Ian, Harvey, Nicholas C., Heawood, A., Holland, R., Howe, A., Kanis, John, Marshall, Tarnya, O'Neill, T. W., Peters, T. J., Redmond, Niamh, Torgerson, David, Turner, David and McCloskey, Eugene. (2018). Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial. The Lancet. 391(10122), pp. 741 - 747. https://doi.org/10.1016/S0140-6736(17)32640-5
Performance of FRAX in clinical practice according to sex and osteoporosis definitions: The Manitoba BMD registry
Leslie, William D., Majumdar, S. R., Morin, Suzanne N., Lix, Lisa, Schousboe, J. T., Ensrud, K. E., Johansson, Helena, McCloskey, Eugene and Kanis, John A.. (2018). Performance of FRAX in clinical practice according to sex and osteoporosis definitions: The Manitoba BMD registry. Osteoporosis International. 29(3), pp. 759 - 767. https://doi.org/10.1007/s00198-018-4415-y
Detection of localized hepatocellular amino acid kinetics by using mass spectrometry imaging of stable isotopes
Arts, Martijn, Soons, Zita, Ellis, Shane R., Pierzchalski, Keely A., Balluff, Benjamin, Eijkel, Gert B., Dubois, Ludwig J., Lieuwes, Natasja G., Agten, Stijn M., Hackeng, Tilman M., Van Loon, Luc, Heeren, Ron M.A. and Damink, Steven W.O.. (2017). Detection of localized hepatocellular amino acid kinetics by using mass spectrometry imaging of stable isotopes. Angewandte Chemie. 56(25), pp. 7146 - 7150. https://doi.org/10.1002/anie.201702669
Mind the (treatment) gap: A global perspective on current and future strategies for prevention of fragility fractures
Harvey, N. C., McCloskey, E. V., Mitchell, P. J., Dawson-Hughes, B., Pierroz, D. D., Reginster, J.-Y. Yves, Rizzoli, R., Cooper, C. and Kanis, J. A.. (2017). Mind the (treatment) gap: A global perspective on current and future strategies for prevention of fragility fractures. Osteoporosis International. 28(5), pp. 1507 - 1529. https://doi.org/10.1007/s00198-016-3894-y
Post-exercise muscle glycogen resynthesis in humans
Burke, Louise M., van Loon, Luc J. C. and Hawley, John A.. (2017). Post-exercise muscle glycogen resynthesis in humans. Journal of Applied Physiology. 122(5), pp. 1055-1067. https://doi.org/0.1152/japplphysiol.00860.2016
The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: individual participant data and meta-analysis of rct's
Tieland, Michael, Franssen, Rinske, Dullemeijer, C., van Dronkelaar, C., Kim, H. K., Ispoglou, T., Zhu, Kun, Prince, R. L., Van Loon, Luc and de Groot, Lisette C.P.G.M.. (2017). The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: individual participant data and meta-analysis of rct's. Journal of Nutrition, Health and Aging. 21(9), pp. 994 - 1001. https://doi.org/10.1007/s12603-017-0896-1
Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: Research for evidence and a scientific statement from the European society for clinical and economic aspects of osteopo
Cianferotti, Luisella, Bertoldo, Francesco, Bischoff-Ferrari, Heike A., Bruyere, O., Cooper, Cyrus, Cutolo, Maurizio, Kanis, John A., Kaufman, Jean-Marc, Reginster, Jean-Yves, Rizzoli, Rene and Brandi, Maria Luisa. (2017). Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: Research for evidence and a scientific statement from the European society for clinical and economic aspects of osteopo. Endocrine. 56(2), pp. 245 - 261. https://doi.org/10.1007/s12020-017-1290-9
Erratum to: diacerein: benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO
Pavelka, Karel, Bruyère, O., Cooper, Cyrus, Kanis, John, Leeb, Burkhard F., Maheu, E., Martel-Pelletier, Johanne, Monfort, Jordi, Pelletier, Jean P., Rizzoli, Rene and Reginster, Jean Yves. (2017). Erratum to: diacerein: benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO. Drugs and Aging. 34(5), pp. 413 - 413. https://doi.org/10.1007/s40266-017-0457-7
Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD Cohort
Martineau, Patrick, Leslie, William, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Hans, Didier and Kanis, John. (2017). Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD Cohort. Journal of Bone and Mineral Research. 32(7), pp. 1568 - 1574. https://doi.org/10.1002/jbmr.3124
Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS
Svedbom, A., Borgström, Fredrik, Hernlund, E., Ström, O., Alekna, V., Bianchi, Maria L., Clark, P., Curiel, M. D., Dimai, Hans P., Jürisson, M., Uusküla, A., Lember, M., Kallikorm, R., Lesnyak, Olga, McCloskey, Eugene, Ershova, Olga, Sanders, Kerrie, Silverman, S., Tamulaitiene, M., ... Kanis, John. (2017). Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS. Quality of Life Research. 27(3), pp. 707 - 716. https://doi.org/10.1007/s11136-017-1748-5
Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis
Dirks, Marlou L., Groen, Bart B.L., Franssen, Rinske, van Kranenburg, Janneau and Van Loon, Luc. (2017). Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis. Journal of Applied Physiology. 122(1), pp. 20 - 27. https://doi.org/10.1152/japplphysiol.00331.2016
Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK: an analysis of anonymous website activity
McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Compston, Juliet E. and Kanis, J.. (2017). Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK: an analysis of anonymous website activity. Osteoporosis International. 28(1), pp. 71 - 76. https://doi.org/10.1007/s00198-016-3696-2
Erratum to: can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, O., Cooper, Cyrus, Arden, Nigel, Branco, J., Brandi, Maria L., Herrero-Beaumont, G., Berenbaum, F., Dennison, Elaine M., Devogelaer, J. P., Hochberg, Marc, Kanis, John, Laslop, A., McAlindon, T., Reiter, Susanne, Richette, P., Rizzoli, Rene and Reginster, Jean Y.. (2017). Erratum to: can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis. Drugs and Aging. 34(5), pp. 411 - 411. https://doi.org/10.1007/s40266-017-0456-8
Increased risk of hip fracture among spouses-evidence of a homogamy effect
Vala, C. H., Oden, Anders, Lorentzon, Mattias, Sundh, V., Johansson, Helena, Karlsson, Magnus, Rosengren, Björn E., Ohlsson, Claes, Johansson, B., Kanis, John and Mellström, Dan. (2017). Increased risk of hip fracture among spouses-evidence of a homogamy effect. Osteoporosis International. 28(1), pp. 95 - 102. https://doi.org/10.1007/s00198-016-3738-9
Total hip bone area affects fracture prediction with FRAX® in Canadian white women
Leslie, William D., Lix, Lisa, Majumdar, S. R., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2017). Total hip bone area affects fracture prediction with FRAX® in Canadian white women. Journal of Clinical Endocrinology and Metabolism. 102(11), pp. 4242 - 4249. https://doi.org/10.1210/jc.2017-01327
Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans
Snijders, Tim, Nederveen, Joshua P., Verdijk, Lex B., Houben, Alfons J.H.M., Goossens, Gijs H., Parise, Gianna and Van Loon, Luc. (2017). Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans. Physiological Reports. 5(10), pp. 1 - 5. https://doi.org/10.14814/phy2.13278
International osteoporosis foundation and European calcified tissue society working group. Recommendations for the screening of adherence to oral bisphosphonates
Diez-Perez, Aldolfo, Naylor, K. E., Abrahamsen, Bo, Agnusdei, D., Brandi, Maria L., Cooper, Cyrus, Dennison, Elaine M., Eriksen, E. F., Gold, D. T., Guañabens, N., Hadji, P., Hiligsmann, Mickaël, Horne, R., Josse, R. G., Kanis, John, Obermayer-Pietsch, Barbara, Prieto-Alhambra, D., Reginster, Jean Y., Rizzoli, Rene, ... Eastell, Richard. (2017). International osteoporosis foundation and European calcified tissue society working group. Recommendations for the screening of adherence to oral bisphosphonates. Osteoporosis International. 28(3), pp. 767 - 774. https://doi.org/10.1007/s00198-017-3906-6
Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting
Kanis, J. A., Cooper, C., Rizzoli, R., Abrahamsen, B., Al-Daghri, N. M., Brandi, M. L., Cannata-Andia, J., Cortet, B., Dimai, H. P., Ferrari, S., Hadji, P., Harvey, N. C., Kraenzlin, M., Kurth, A., McCloskey, E., Minisola, S., Thomas, T. and Reginster, J.-Y.. (2017). Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting. Osteoporosis International. 28(7), pp. 2023 - 2034. https://doi.org/10.1007/s00198-017-4009-0
Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate
Lesnyak, Olga, Sahakyan, S., Zakroyeva, A., Bilezikian, John P., Hutchings, N., Babalyan, V., Galstyan, R., Lebedev, A., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene and Kanis, John. (2017). Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate. Archives of Osteoporosis. 12(98), pp. 1 - 9. https://doi.org/10.1007/s11657-017-0392-6
Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures - results from the ICUROS
Svedbom, A., Borgstom, F., Hernlund, E., Strom, Oskar, Alekna, V., Bianchi, Maria L., Clark, Patricia M., Curiel, M. D., Dimai, Hans P., Jurisson, Mikk, Kallikorm, R., Lember, M., Lesnyak, Olga, McCloskey, Eugene, Sanders, Kerry M., Silverman, S., Solodovnikov, A., Tamulaitiene, M., Thomas, T., ... Kanis, John. (2017). Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures - results from the ICUROS. Osteoporosis International. 29(3), pp. 557 - 566. https://doi.org/10.1007/s00198-017-4317-4
FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry
Leslie, William, Majumdar, S. R., Morin, Suzanne N., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2017). FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry. Osteoporosis International. 28(9), pp. 2557 - 2564. https://doi.org/10.1007/s00198-017-4091-3
Postexercise muscle glycogen resynthesis in humans
Burke, Louise, Van Loon, Luc and Hawley, John. (2017). Postexercise muscle glycogen resynthesis in humans. Journal of Applied Physiology. 122(5), pp. 1055 - 1067. https://doi.org/10.1152/japplphysiol.00860.2016
Consideration of insects as a source of dietary protein for human consumption
Churchward-Venne, T. A., Pinckaers, Philippe J. M., van Loon, Joop J. A. and Van Loon, Luc. (2017). Consideration of insects as a source of dietary protein for human consumption. Nutrition Reviews. 75(12), pp. 1035 - 1045. https://doi.org/10.1093/nutrit/nux057
Management of aromatase inhibitor-associated bone loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG
Hadji, P., Aapro, Matti S., Body, Jean J., Gnant, Michael, Brandi, Maria L., Reginster, Jean Y., Zillikens, M. C., Glüer, C. C., de Villiers, T., Baber, Rod, Roodman, G. David, Cooper, Cyrus, Langdahl, Bente Lomholt, Palacios, Santiago, Kanis, John, Al-Daghri, Nasser M., Nogues, Xavier, Eriksen, Erik F., Kurth, Andreas, ... Coleman, Robert E.. (2017). Management of aromatase inhibitor-associated bone loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG. Journal of Bone Oncology. 7, pp. 1 - 12. https://doi.org/10.1016/j.jbo.2017.03.001
Protein supplementation augments muscle fiber hypertrophy but does not modulate satellite cell content during prolonged resistance-type exercise training in frail elderly
Dirks, Marlou L., Tieland, Michael, Verdijk, Lex B., Losen, Mario, Nilwik, Rachel, Mensink, Marco, de Groot, Lisette C.P.G.M. and Van Loon, Luc. (2017). Protein supplementation augments muscle fiber hypertrophy but does not modulate satellite cell content during prolonged resistance-type exercise training in frail elderly. Journal of the American Medical Directors Association (JAMDA): long-term care: management, applied research and clinical issues. 18(7), pp. 608 - 615. https://doi.org/10.1016/j.jamda.2017.02.006
Glucose plus fructose ingestion for post exercise recovery greater than the sum of its parts?
Gonzalez, Javier T., Fuchs, Cas J., Betts, James A. and Van Loon, Luc. (2017). Glucose plus fructose ingestion for post exercise recovery greater than the sum of its parts? Nutrients. 9(4), pp. 1 - 15. https://doi.org/10.3390/nu9040344
Imminent risk of fracture after fracture
Johansson, Helena, Siggeirsdottir, Kristin, Harvey, Nicholas C., Oden, Anders, Gudnason, Vilmundur, McCloskey, Eugene, Sigurdsson, Gunnar and Kanis, John. (2017). Imminent risk of fracture after fracture. Osteoporosis International. 28(3), pp. 775 - 780. https://doi.org/10.1007/s00198-016-3868-0
Clinical settings in knee osteoarthritis: Pathophysiology guides treatment
Herrero-Beaumont, Gabriel, Roman-Blas, Jorge A., Bruyère, Olivier, Cooper, Cyrus, Kanis, John, Maggi, S., Rizzoli, René and Reginster, Jean-Yves. (2017). Clinical settings in knee osteoarthritis: Pathophysiology guides treatment. Maturitas. 96, pp. 54 - 57. https://doi.org/10.1016/j.maturitas.2016.11.013
Twenty-four-hour biological variation profiles of cardiac troponin I in individuals with or without chronic kidney disease
Van Der Linden, Noreen, Hilderink, Judith M., Cornelis, Tom, Kimenai, Dorien M., Klinkenberg, Lieke J.J., Van Doorn, William P., Litjens, Elisabeth J.R., Van Suijlen, Jeroen D.E., Van Loon, Luc, Bekers, Otto, Kooman, Jeroen P. and Meex, Steven J.R.. (2017). Twenty-four-hour biological variation profiles of cardiac troponin I in individuals with or without chronic kidney disease. Clinical Chemistry (Washington, DC): international journal of molecular diagnostics and laboratory medicine. 63(10), pp. 1655 - 1656. https://doi.org/10.1373/clinchem.2017.275107
Clinical usefulness of bone turnover marker concentrations in osteoporosis
Morris, H. A., Eastell, R., Jorgesen, N. R., Cavalier, E., Vasikaran, S., Chubb, S. A. P., Kanis, J. A., Cooper, C. and Makris, K.. (2017). Clinical usefulness of bone turnover marker concentrations in osteoporosis. Clinica Chimica Acta. 467, pp. 34 - 41. https://doi.org/10.1016/j.cca.2016.06.036
Dietary protein intake and distribution patterns of well-trained Dutch athletes
Gillen, Jenna B., Trommelen, Jorn, Wardenaar, Floris C., Brinkmans, Naomi Y.J., Versteegen, Joline J., Jonvik, Kristin L., Kapp, Christoph, de Vries, Jeanne, van den Borne, Joost J.G.C., Gibala, M. J. and Van Loon, Luc. (2017). Dietary protein intake and distribution patterns of well-trained Dutch athletes. International Journal of Sport Nutrition and Exercise Metabolism. 27(2), pp. 105 - 114. https://doi.org/10.1123/ijsnem.2016-0154
Epidemiology of hip fracture and the development of FRAX in Ukraine
Povoroznyuk, V. V., Grygorieva, N. V., Kanis, John, McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Korzh, M. O., Strafun, S. S., Vaida, V. M., Klymovytsky, F. V., Vlasenko, R. R. and Forosenko, V. S.. (2017). Epidemiology of hip fracture and the development of FRAX in Ukraine. Archives of Osteoporosis. 12(1), pp. 1 - 6. https://doi.org/10.1007/s11657-017-0343-2
Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice
Dijk, Francina J., van Dijk, Miriam, Walrand, Stéphane, Van Loon, Luc, van Norren, Klaske and Luiking, Yvette C.. (2017). Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice. Clinical Nutrition ESPEN. 24, pp. 127 - 133. https://doi.org/doi.org/10.1016/j.clnesp.2017.12.013
Extensive type ii muscle fiber atrophy in elderly female hip fracture patients
Kramer, Irene F., Snijders, Tim, Smeets, Joey S.J., Leenders, Marika, van Kranenburg, Janneau, den Hoed, Marcel, Verdijk, Lex B., Poeze, Martijn and Van Loon, Luc. (2017). Extensive type ii muscle fiber atrophy in elderly female hip fracture patients. Journal of Gerontology Series A: Biological Sciences and Medical Sciences. 72(10), pp. 1369 - 1375. https://doi.org/10.1093/gerona/glw253
Overview of fracture prediction tools
Kanis, John, A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, McCloskey, Eugene V. and Leslie, William D.. (2017). Overview of fracture prediction tools. Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health. 20(3), pp. 444-450. https://doi.org/10.1016/j.jocd.2017.06.013
FRAX- vs. T-score-based intervention thresholds for osteoporosis
Johansson, Helena, Azizieh, F., al Ali, N., Alessa, T., Harvey, Nicholas C., McCloskey, Eugene and Kanis, John A.. (2017). FRAX- vs. T-score-based intervention thresholds for osteoporosis. Osteoporosis International. 28(11), pp. 3099 - 3105. https://doi.org/10.1007/s00198-017-4160-7
Association of mental disorders and related medication use with risk for major osteoporotic fractures
Bolton, James M., Morin, Suzanne N., Majumdar, S. R., Sareen, Jitender, Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John and Leslie, William. (2017). Association of mental disorders and related medication use with risk for major osteoporotic fractures. JAMA Psychiatry. 74(6), pp. 641 - 648. https://doi.org/10.1001/jamapsychiatry.2017.0449
Fructose and sucrose intake increase exogenous carbohydrate oxidation during exercise
Trommelen, Jorn, Fuchs, Cas J., Beelen, M, Lenaerts, Kaatje, Jeukendrup, A. E., Cermak, N. and Van Loon, Luc. (2017). Fructose and sucrose intake increase exogenous carbohydrate oxidation during exercise. Nutrients. 9(2), pp. 1 - 12. https://doi.org/10.3390/nu9020167
The effect of abaloparatide-SC on fracture risk is independent of baseline FRAX fracture probability: a post hoc analysis of the ACTIVE study
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Harvey, Nicholas C., Jiang, Hai, Modin, Sara, Fitzpatrick, Lorraine and Kanis, John. (2017). The effect of abaloparatide-SC on fracture risk is independent of baseline FRAX fracture probability: a post hoc analysis of the ACTIVE study. Journal of Bone and Mineral Research. 32(8), pp. 1625 - 1631. https://doi.org/10.1002/jbmr.3163
Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial
Kouw, Imre W.K., Holwerda, Andrew M., Trommelen, Jorn, Kramer, Irene Fleur, Bastiaanse, Jacqueline, Halson, Shona, Wodzig, Will K.W.H., Verdijk, Lex B. and Van Loon, Luc. (2017). Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial. The Journal of Nutrition. 147(12), pp. 2252 - 2261. https://doi.org/10.3945/jn.117.254532
Erratum to: identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting
Kanis, John, Cooper, Cyrus, Rizzoli, Rene, Abrahamsen, Bo, Al-Daghri, N. M., Brandi, Maria L., Cannata, J. B., Cortet, B., Dimai, Hans P., Ferrari, S., Hadji, P., Harvey, Nicholas C., Kraenzlin, M., Kurth, Andreas, McCloskey, Eugene, Minisola, Salvatore, Thomas, T. and Reginster, Jean Y.. (2017). Erratum to: identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting. Osteoporosis International. 28(11), pp. 3285 - 3286. https://doi.org/10.1007/s00198-017-4161-6
Sodium nitrate ingestion increases skeletal muscle nitrate content in humans
Nyakayiru, Jean, Kouw, Imre W.K., Cermak, N, Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017). Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. Journal of Applied Physiology. 123(3), pp. 637 - 644. https://doi.org/10.1152/japplphysiol.01036.2016
Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men
Tsintzas, Kostas, Stephens, F. B., Snijders, Tim, Wall, Benjamin T., Cooper, Scott, Mallinson, Joanne, Verdijk, Lex B. and Van Loon, Luc. (2017). Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men. Experimental Gerontology. 93, pp. 36 - 45. https://doi.org/10.1016/j.exger.2017.03.018
Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review
Beaudart, Charlotte, Dawson, A., Shaw, S. C., Harvey, Nicholas C., Kanis, John, Binkley, Neil, Reginster, Jean Yves, Chapurlat, R., Chan, D. C., Bruyère, O., Rizzoli, Rene, Cooper, Cyrus and Dennison, Elaine M.. (2017). Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review. Osteoporosis International. 28(6), pp. 1817 - 1833. https://doi.org/10.1007/s00198-017-3980-9
FRAX update
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, Leslie, William D. and McCloskey, Eugene V.. (2017). FRAX update. Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health. 20(3), pp. 360 - 367. https://doi.org/10.1016/j.jocd.2017.06.022
Commentaries on Viewpoint: A time for exercise: the exercise window
Boule, Normand G., Terada, Tasuku, Francois, Monique E., Hawley, John, Cotter, James D., Kruse, Nicholas T., McDonald, Matthew W., Olver, T D., Paoli, Antonio, Sacchetti, Massimo, Di Luigi, Luigi, van Dijk, Jan W., Van Loon, Luc, Yardley, Jane E., DiPietro, Loretta, Gribok, Andrei and Rumpler, William. (2017). Commentaries on Viewpoint: A time for exercise: the exercise window. Journal of Applied Physiology. 122(1), pp. 210 - 213. https://doi.org/10.1152/japplphysiol.00938.2016
No effect of acute and 6-day nitrate supplementation on VO2 and time-trial performance in highly trained cyclists
Nyakayiru, Jean, Jonvik, Kristin L., Pinckaers, Philippe J.M., Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017). No effect of acute and 6-day nitrate supplementation on VO2 and time-trial performance in highly trained cyclists. International Journal of Sport Nutrition and Exercise Metabolism. 27(1), pp. 11 - 17. https://doi.org/10.1123/ijsnem.2016-0034
Evaluation of clinical risk factors for osteoporosis and applicability of the FRAX tool in Joinville City, southern Brazil
Silva, Dalisbor M.W., Borba, Victoria Z.C. and Kanis, John. (2017). Evaluation of clinical risk factors for osteoporosis and applicability of the FRAX tool in Joinville City, southern Brazil. Archives of Osteoporosis. 12(111), pp. 1 - 8. https://doi.org/10.1007/s11657-017-0405-5
Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position
Holwerda, Andrew M., Lenaerts, Kaatje, Bierau, Jörgen, Wodzig, Will K.W.H. and Van Loon, Luc. (2017). Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position. Applied Physiology, Nutrition and Metabolism. 42(7), pp. 738 - 743. https://doi.org/10.1139/apnm-2016-0522
The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF)
Harvey, Nicholas C., Biver, Emmanuel, Kaufman, J,, Bauer, Jürgen M., Branco, J., Brandi, Maria Luisa, Bruyère, O., Coxam, V., Cruz-Jentoft, Alfonso J., Czerwinski, E., Dimai, Hans P., Fardellone, P., Landi, Francesco, Reginster, Jean Yves, Dawson-Hughes, Bess, Kanis, John, Rizzoli, Rene and Cooper, Cyrus. (2017). The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF). Osteoporosis International. 28(2), pp. 447 - 462. https://doi.org/10.1007/s00198-016-3773-6
UK clinical guideline for the prevention and treatment of osteoporosis
Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Gittoes, Neil, Gregson, C., Harvey, Nicholas C., Hope, S., Kanis, John, McCloskey, Eugene, Poole, Kenneth E.S., Reid, David M., Selby, P., Thompson, F., Thurston, A. and Vine, N.. (2017). UK clinical guideline for the prevention and treatment of osteoporosis. Archives of Osteoporosis. 12(43), pp. 1 - 24. https://doi.org/10.1007/s11657-017-0324-5
Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players
Nyakayiru, Jean, Jonvik, Kristin L., Trommelen, Jorn, Pinckaers, Philippe J.M., Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017). Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players. Nutrients. 9(3), pp. 1 - 10. https://doi.org/10.3390/nu9030314
The prevention of fragility fractures in patients with non-metastatic prostate cancer: A position statement by the international osteoporosis foundation
Cianferotti, Luisella, Bertoldo, Francesco, Carini, Marco, Kanis, John A., Lapini, Alberto, Longo, Nicola, Martorana, Giuseppe, Mirone, Vincenzo, Reginster, Jean-Yves, Rizzoli, Rene and Brandi, Maria Luisa. (2017). The prevention of fragility fractures in patients with non-metastatic prostate cancer: A position statement by the international osteoporosis foundation. Oncotarget. 8(43), pp. 75646 - 75663. https://doi.org/10.18632/oncotarget.17980
FRAX-based intervention and assessment thresholds in seven Latin American countries
Clark, P., Denova-Gutiérrez, E., Zerbini, Cristiano, Sanchez, A., Messina, O. D., Jaller, J. J., Campusano, C., Orces, C. H., Riera, G., Johansson, Helena and Kanis, John. (2017). FRAX-based intervention and assessment thresholds in seven Latin American countries. Osteoporosis International. 29(3), pp. 707 - 715. https://doi.org/10.1007/s00198-017-4341-4
Seasonal variation in vitamin d status in elite athletes: a longitudinal study
Backx, E. M.P., van der Avoort, Cindy van, Tieland, Michael, Maase, K., Kies, A. K., Van Loon, Luc, de Groot, Lisette C.P.G.M. and Mensink, M.. (2017). Seasonal variation in vitamin d status in elite athletes: a longitudinal study. International Journal of Sport Nutrition and Exercise Metabolism. 27(1), pp. 6 - 10. https://doi.org/10.1123/ijsnem.2016-0177
Glycemic control during consecutive days with prolongedwalking exercise in individuals with type 1 diabetes mellitus
van Dijk, Jan Willem, Eijsvogels, Thijs M., Nyakayiru, Jean, Schreuder, Tim H. A., Hopman, Maria T., Thijssen, Dick H. and Van Loon, Lucas. (2016). Glycemic control during consecutive days with prolongedwalking exercise in individuals with type 1 diabetes mellitus. Diabetes Research and Clinical Practice. 117, pp. 74 - 81. https://doi.org/10.1016/j.diabres.2016.04.053
May bed rest cause greater muscle loss than limb immobilization?
Dirks, M. L., Backx, E. M. P., Wall, B. T., Verdijk, L. B. and van Loon, L.. (2016). May bed rest cause greater muscle loss than limb immobilization? Acta Physiologica. 218(1), pp. 10-12. https://doi.org/10.1111/apha.12699
Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study
Rozenberg, Robert, Mankowski, Robert T., van Loon, Luc, Langendonk, Janneke G., Sijbrands, Eric J. G., van den Meiracker, Anton H., Stam, Henk J. and Praet, Stephan F. E.. (2016). Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study. European Journal of Medical Research. 21(1), pp. 1 - 8. https://doi.org/10.1186/s40001-015-0194-5
Adjusting hip fracture probability in men and women using hip axis length: The Manitoba Bone Density Database
Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John Anthony. (2016). Adjusting hip fracture probability in men and women using hip axis length: The Manitoba Bone Density Database. Journal of Clinical Densitometry. 19(3), pp. 326 - 331. https://doi.org/10.1016/j.jocd.2015.07.004
A systematic review of intervention thresholds based on FRAX: A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation
Kanis, John A., Harvey, Nicholas C., Cooper, Cyrus, Johansson, Helena, Oden, Anders, McCloskey, Eugene V., The Advisory Board of the National Osteoporosis Guideline Group, and The Advisory Board of the National Osteoporosis Guideline Group. (2016). A systematic review of intervention thresholds based on FRAX: A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Archives of Osteoporosis. https://doi.org/10.1007/s11657-016-0278-z
FRAX predicts incident falls in elderly men: findings from MrOs Sweden
Harvey, Nicholas C., Johansson, Helena, Oden, Anders, Karlsson, Magnus, Rosengren, Björn E., Ljunggren, Östen, Cooper, Cyrus, McCloskey, Eugene V., Kanis, John A., Ohlsson, C. and Mellström, Dan. (2016). FRAX predicts incident falls in elderly men: findings from MrOs Sweden. Osteoporosis International. 27(1), pp. 267 - 274. https://doi.org/10.1007/s00198-015-3295-7
Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey
Bruyère, O., Beaudart, Charlotte, Reginster, Jean Yves, Buckinx, F., Schoene, D., Hirani, V., Cooper, Cyrus, Kanis, John, Rizzoli, Rene, McCloskey, Eugene, Cederholm, T., Cruz-Jentoft, Alfonso J. and Freiberger, E.. (2016). Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey. European Geriatric Medicine. 7(3), pp. 243 - 246. https://doi.org/10.1016/j.eurger.2015.12.009
Cardiac Troponin T and i Release after a 30-km Run
Klinkenberg, Lieke J. J., Luyten, Peter, Van Der Linden, Noreen, Urgel, Kim, Snijders, Daniëlle P. C., Knackstedt, Christian, Dennert, Robert, Kietselaer, Bastiaan L. J. H., Mingels, Alma M. A., Cardinaels, Eline P. M., Peeters, Frederique E. C. M., Van Suijlen, Jeroen D. E., Kate, Joop Ten, Marsch, Elke, Theelen, Thomas L., Sluimer, Judith C., Wouters, Kristiaan, Bekers, Otto, Bekkers, Sebastiaan C. A. M., ... Meex, Steven J. R.. (2016). Cardiac Troponin T and i Release after a 30-km Run. American Journal of Cardiology. 118(2), pp. 281 - 287. https://doi.org/10.1016/j.amjcard.2016.04.030
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, Nathalie, Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, Rene, Cortet, Bernard, Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., Strandberg, Timo, Alvarez, M. N., ... Treml, J.. (2016). A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. European Geriatric Medicine. 7(6), pp. 519 - 525. https://doi.org/10.1016/j.eurger.2016.04.012
Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population
van der Linden, Noreen, Klinkenberg, Lieke J. J., Bekers, Otto, van Loon, Luc, Van Dieijen-Visser, Marja P., Zeegers, Maurice P. and Meex, Steven J. R.. (2016). Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population. Medicine. https://doi.org/10.1097/MD.0000000000005703
Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion
Wall, Benjamin T., Dirks, Marlou L., Snijders, Tim, Willem van Dijk, Jan, Fritsch, Mario, Verdijk, Lex B. and Van Loon, Luc. (2016). Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion. American Journal of Physiology - Endocrinology and Metabolism. https://doi.org/10.1152/ajpendo.00227.2015
Direct comparison of FRAX(R) and a simplified fracture risk assessment tool in routine clinical practice: A registry-based cohort study
Leslie, William D., Majumdar, S. R., Lix, Lisa M., Josse, R. G., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2016). Direct comparison of FRAX(R) and a simplified fracture risk assessment tool in routine clinical practice: A registry-based cohort study. Osteoporosis International. 27(9), pp. 2689 - 2695. https://doi.org/10.1007/s00198-016-3613-8
A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, Nathalie, Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John, Reginster, Jean Y., Rizzoli, Rene, Cortet, B., Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., Strandberg, Timo E., Alvarez, M. N., ... Macijauskien, J. (2016). A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clinical and Experimental Research. 28(4), pp. 797 - 803. https://doi.org/10.1007/s40520-016-0588-4
FRAX updates 2016
McCloskey, Eugene V., Harvey, Nicholas C., Johansson, Helena and Kanis, John A.. (2016). FRAX updates 2016. Current Opinion in Rheumatology. 28(4), pp. 433 - 441. https://doi.org/10.1097/BOR.0000000000000304
Diacerein: Benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO
Pavelka, Karel, Bruyère, Olivier, Cooper, Cyrus, Kanis, John A., Leeb, Burkhard F., Maheu, Emmanuel, Martel-Pelletier, Johanne, Monfort, Jordi, Pelletier, Jean-Pierre, Rizzoli, Rene and Reginster, Jean-Yves. (2016). Diacerein: Benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO. Drugs and Aging. 33(2), pp. 75 - 85. https://doi.org/10.1007/s40266-016-0347-4
Impact of diet composition on blood glucose regulation
Russell, Wendy R., Baka, Athanasia, Bjorck, Inger, Delzenne, Nathalie, Gao, Dan, Griffiths, Helen R., Hadjilucas, Ellie, Juvonen, Kristiina, Lahtinen, Sampo, Lansink, Mirian, van Loon, Luc, Mykkanen, Hannu, Ostman, Elin, Riccardi, Gabrielle, Vinoy, Sophie and Weickert, Martin O.. (2016). Impact of diet composition on blood glucose regulation. Critical Reviews in Food Science and Nutrition. 56(4), pp. 541 - 590. https://doi.org/10.1080/10408398.2013.792772
The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient
Sipers, Walther M. W. H., Verdijk, Lex B., Sipers, Simone J. E., Schols, Jos M. G. A. and Van Loon, Luc. (2016). The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient. Journal of the American Medical Directors Association. 17(5), pp. 1 - 7. https://doi.org/10.1016/j.jamda.2016.02.026
Quality of life, resource use, and costs related to hip fracture in Estonia
Jurisson, Mikk, Pisarev, Heti, Kanis, John, Borgstrom, F., Svedbom, A., Kallikorm, R., Lember, M. and Uusküla, A.. (2016). Quality of life, resource use, and costs related to hip fracture in Estonia. Osteoporosis International. 27(8), pp. 2555 - 2566. https://doi.org/10.1007/s00198-016-3544-4
Resistance training increases skeletal muscle capillarization in healthy older men
Verdijk, Lex B., Snijders, Tim, Holloway, Tanya M., Van Kranenburg, Janneau and van Loon, Luc. (2016). Resistance training increases skeletal muscle capillarization in healthy older men. Medicine and Science in Sports and Exercise. 48(11), pp. 2157 - 2164. https://doi.org/10.1249/MSS.0000000000001019
Habitual Dietary Nitrate Intake in Highly Trained Athletes
Jonvik, Kristin L., Nyakayiru, Jean, Willem van Dijk, Jan, Wardenaar, Floris C., Van Loon, Lucas and Verdijk, Lex B.. (2016). Habitual Dietary Nitrate Intake in Highly Trained Athletes. International Journal of Sport Nutrition and Exercise Metabolism. https://doi.org/10.1123/ijsnem.2016-0239
Protein intake and lean body mass preservation during energy intake restriction in overweight older adults
Backx, E. M. P., Tieland, Michael, Borgonjen-Van Den Berg, Karin J., Claessen, P. R., Van Loon, Lucas and de Groot, Lisette C.P.G.M.. (2016). Protein intake and lean body mass preservation during energy intake restriction in overweight older adults. International Journal of Obesity. https://doi.org/10.1038/ijo.2015.182
Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training
Snijders, Tim, Smeets, Joey S. J., Van Kranenburg, Janneau, Kies, A. K., Van Loon, Lucas and Verdijk, Lex B.. (2016). Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training. Acta Physiologica. https://doi.org/10.1111/apha.12609
Resistance exercise augments postprandial overnight muscle protein synthesis rates
Trommelen, Jorn, Holwerda, Andrew M., Kouw, Imre W. K., Langer, Henning, Halson, Shona L., Verdijk, Lex B. and van Loon, Luc J. C.. (2016). Resistance exercise augments postprandial overnight muscle protein synthesis rates. Medicine and Science in Sports and Exercise. 48(12), pp. 2517-2525. https://doi.org/10.1249/MSS.0000000000001045
Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning
Wall, Benjamin T., Burd, Nicholas A., Franssen, Rinske, Gorissen, Stefan H. M., Snijders, Tim, Senden, Joan M., Gijsen, Annemie P. and van Loon, Luc. (2016). Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning. American Journal of Physiology - Endocrinology and Metabolism. 311(6), pp. E964-E973. https://doi.org/10.1152/ajpendo.00325.2016
Longer duration of diabetes strongly impacts fracture risk assessment: The Manitoba BMD cohort
Majumdar, Sumit R., Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2016). Longer duration of diabetes strongly impacts fracture risk assessment: The Manitoba BMD cohort. Journal of Clinical Endocrinology and Metabolism. 101(11), pp. 4489 - 4496. https://doi.org/10.1210/jc.2016-2569
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K. E., Vellas, B., Maggi, S. and Strandberg, T.. (2016). A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. Aging Clinical and Experimental Research. 28(4), pp. 797 - 803. https://doi.org/10.1007/s40520-016-0588-4
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K. E., Vellas, B., Maggi, S. and Strandberg, T.. (2016). A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. Journal of Nutrition, Health and Aging. 20(6), pp. 647 - 652. https://doi.org/10.1007/s12603-016-0741-y
Cost-effectiveness of intervention thresholds for the treatment of osteoporosis based on FRAX(R) in Portugal
Marques, Andréa, Lourenço, Óscar, Ortsäter, Gustaf, Borgstrom, Fredrik, Kanis, John A. and da Silva, José António P.. (2016). Cost-effectiveness of intervention thresholds for the treatment of osteoporosis based on FRAX(R) in Portugal. Calcified Tissue International. 99(2), pp. 131 - 141. https://doi.org/10.1007/s00223-016-0132-8
Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture
Ferrari, S., Reginster, Jean Yves, Brandi, Maria Luisa, Kanis, John A., Devogelaer, J. P., Kaufman, J. M., Féron, J. M., Kurth, Andreas and Rizzoli, René. (2016). Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture. Archives of Osteoporosis. 11(1), pp. 1 - 12. https://doi.org/10.1007/s11657-016-0292-1
Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and O
Cooper, Cyrus, Bardin, Thomas, Brandi, M. L., Cacoub, Patrice, Caminis, John, Civitelli, Roberto, Cutolo, Maurizio, Dere, Willard, Devogelaer, Jean-Pierre, Diez-Perez, Adolfo, Einhorn, Thomas A., Emonts, Patrick, Ethgen, Olivier, Kanis, John A., Kaufman, Jean-Marc, Kvien, Tore K., Lems, Willem F., McCloskey, Eugene, Miossec, Pierre, ... Reginster, Jean-Yves. (2016). Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and O. Aging Clinical and Experimental Research. 28(1), pp. 1 - 16. https://doi.org/10.1007/s40520-015-0522-1
SIGN Guidelines for Scotland: BMD Versus FRAX Versus QFracture
Kanis, John A., Compston, Juliet, Cooper, Cyrus, Harvey, Nicholas C., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2016). SIGN Guidelines for Scotland: BMD Versus FRAX Versus QFracture. Calcified Tissue International. 98(5), pp. 417 - 425. https://doi.org/10.1007/s00223-015-0092-4
A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting
Bruyère, Olivier, Cooper, Cyrus, Pelletier, Jean-Pierre, Maheu, Emmanuel, Rannou, François, Branco, Jaime, Brandi, Maria Luisa, Kanis, John A., Altman, Roy D., Hochberg, Marc C., Martel-Pelletier, Johanne and Reginster, Jean-Yves. (2016). A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting. Seminars in Arthritis and Rheumatism. 45(4), pp. S3 - S11. https://doi.org/10.1016/j.semarthrit.2015.11.010
Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction
Klinkenberg, Lieke J. J., Wildi, Karin, Van Der Linden, Noreen, Kouw, Imre W. K., Niens, Marijke, Twerenbold, Raphael, Gimenez, Maria Rubini, Puelacher, Christian, Neuhaus, Jean Daniel, Hillinger, Petra, Nestelberger, Thomas, Boeddinghaus, Jasper, Grimm, Karin, Sabti, Zaid, Bons, Judith A. P., Van Suijlen, Jeroen D. E., Tan, Frans E. S., Kate, Joop Ten, Bekers, Otto, ... Meex, Steven J. R.. (2016). Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction. Clinical Chemistry. 62(12), pp. 1602 - 1611. https://doi.org/10.1373/clinchem.2016.257485
A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX
McCloskey, Eugene, Oden, Anders, Harvey, Nicholas C., Leslie, William, Hans, D., Johansson, Helena, Barkmann, Reinhard, Boutroy, Stephanie, Brown, J. P., Chapurlat, Roland D., Elders, Petra J. M., Fujita, Yuki, Glüer, Claus C., Goltzman, David, Iki, Masayuki, Karlsson, M. K., Kindmark, Andreas, Kotowicz, Mark, Kurumatani, Norio, ... Kanis, John A.. (2016). A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX. Journal of Bone and Mineral Research. 31(5), pp. 940 - 948. https://doi.org/10.1002/jbmr.2734
Sarcopenia in daily practice: Assessment and management
Beaudart, Charlotte, McCloskey, Eugene, Bruyère, Olivier, Cesari, Matteo, Rolland, Yves, Rizzoli, Rene, de Carvalho, Islène Araujo, Thiyagarajan, Jotheeswaran Amuthavalli, Bautmans, Ivan, Bertière, Marie-Claude, Brandi, Maria Luisa, Al-Daghri, Nasser M., Burlet, Nansa, Cavalier, Etienne, Cerreta, Francesca, Cherubini, Antonio, Fielding, Roger, Gielen, Evelien, Landi, Francesco, ... Cooper, Cyrus. (2016). Sarcopenia in daily practice: Assessment and management. BMC Geriatrics. 16(170), pp. 1 - 10. https://doi.org/10.1186/s12877-016-0349-4
Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness
Hangelbroek, Roland W. J., Fazelzadeh, Parastoo, Tieland, Michael, Boekschoten, Mark V., Hooiveld, Guido J. E. J., van Duynhoven, John P. M., Timmons, James A., Verdijk, Lex B., de Groot, Lisette C. P. G. M., Van Loon, Luc and Müller, Michael. (2016). Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness. Journal Cachexia Sarcopenia Muscle. 7(5), pp. 604 - 614. https://doi.org/10.1002/jcsm.12099
The impact of 1-year vitamin D supplementation on vitamin D status in athletes: A dose-response study
Backx, E. M. P., Tieland, Michael, Maase, K., Kies, A. K., Mensink, M., Van Loon, Luc and de Groot, Lisette C. P. G. M.. (2016). The impact of 1-year vitamin D supplementation on vitamin D status in athletes: A dose-response study. European Journal of Clinical Nutrition. 70(9), pp. 1009 - 1014. https://doi.org/10.1038/ejcn.2016.133
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990--2015: a systematic analysis for the Global Burden of Disease Study 2015
Vos, Theo, Allen, Christine, Arora, Megha, Barber, Ryan M., Bhutta, Zulfiqar A., Brown, Alexandria, Carter, Austin, Casey, Daniel C., Charlson, Fiona J., Chen, Alan Z., Coggeshall, Megan, Cornaby, Leslie, Dandona, Lalit, Dicker, Daniel J., Dilegge, Tina, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Tom, ... Murray, Christopher J. L.. (2016). Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990--2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1545 - 1602. https://doi.org/10.1016/S0140-6736(16)31678-6
Can we treat to target in osteoporosis?
McCloskey, Eugene, Harvey, Nicholas C. and Kanis, John. (2015). Can we treat to target in osteoporosis? International Journal of Clinical Rheumatology. 10(1), pp. 1 - 4. https://doi.org/10.2217/ijr.14.59
Burden of high fracture probability worldwide: Secular increases 2010--2040
Oden, Anders, McCloskey, Eugene V., Kanis, John A., Harvey, Nicholas C. and Johansson, Helena. (2015). Burden of high fracture probability worldwide: Secular increases 2010--2040. Osteoporosis International. 26(9), pp. 2243 - 2248. https://doi.org/10.1007/s00198-015-3154-6
Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis
Reginster, Jean Yves, Cooper, Cyrus, Hochberg, Marc, Pelletier, Jean Pierre, Rizzoli, R, Kanis, John A., Abadie, Eric, Maheu, E., Brandi, Maria Luisa, Devogelaer, J. P., Branco, J., Herrero-Beaumont, G., D'Hooghe, Pieter and Bruyère, O.. (2015). Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis. Current Medical Research and Opinion. 31(5), pp. 1041 - 1045. https://doi.org/10.1185/03007995.2015.1027183
Intervention thresholds and the diagnosis of osteoporosis
Kanis, John A., McCloskey, Eugene, Harvey, Nicholas C., Johansson, Helena and Leslie, William D.. (2015). Intervention thresholds and the diagnosis of osteoporosis. Journal of Bone and Mineral Research. 30(10), pp. 1747 - 1753. https://doi.org/10.1002/jbmr.2531
Hypoxia induces a prothrombotic state independently of the physical activity
Ninivaggi, Marisa, De Laat, Marieke, Lancé, Marcus M. D., Kicken, Cécile H., Pelkmans, Leonie, Bloemen, Saartje, Dirks, Marlou L., Van Loon, Luc, Govers-Riemslag, José W. P., Lindhout, Theo, Konings, Joke and De Laat, Bas. (2015). Hypoxia induces a prothrombotic state independently of the physical activity. PLoS ONE. 10(10), pp. 1 - 14. https://doi.org/10.1371/journal.pone.0141797
Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool
Javaid, M. K., Kyer, C., Mitchell, P. J., Chana, J., Moss, C., Edwards, M. H., McLellan, A. R., Stenmark, J., Pierroz, D. D., Schneider, M. C., Kanis, John A., Akesson, K. and Cooper, Cyrus. (2015). Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool. Osteoporosis International. 26(11), pp. 2573 - 2578. https://doi.org/10.1007/s00198-015-3192-0
Health economic aspects of vertebral augmentation procedures
Borgström, F., Beall, D. P., Berven, S., Boonen, S., Christie, S., Kallmes, D. F., Kanis, John A., Olafsson, G., Singer, A. J. and Åkesson, K.. (2015). Health economic aspects of vertebral augmentation procedures. Osteoporosis International. 26(4), pp. 1239 - 1249. https://doi.org/10.1007/s00198-014-2953-5
Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice
Harvey, N. C., Glüer, C. C., Binkley, N., McCloskey, E. V., Brandi, M. L., Cooper, C., Kendler, D., Lamy, O., Laslop, A., Camargos, B. M., Reginster, J-Y, Rizzoli, R. and Kanis, J. A.. (2015). Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice. Bone. 78, pp. 216 - 224. https://doi.org/10.1016/j.bone.2015.05.016
Adjusting fracture probability by trabecular bone score
McCloskey, Eugene V., Oden, Anders, Harvey, Nicholas C., Leslie, William D., Hans, Didier, Johansson, Helena and Kanis, John A.. (2015). Adjusting fracture probability by trabecular bone score. Calcified Tissue International. 96(6), pp. 500 - 509. https://doi.org/10.1007/s00223-015-9980-x
Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty
Arden, Nigel, Richette, Pascal, Cooper, Cyrus, Bruyère, Olivier, Abadie, Eric, Branco, Jaime, Brandi, Maria Luisa, Berenbaum, Francis, Clerc, Cécile, Dennison, Elaine M., Devogelaer, Jean-Pierre, Hochberg, Marc, D'Hooghe, Pieter, Herrero-Beaumont, Gabriel, Kanis, John A., Laslop, Andrea, Leblanc, Véronique, Maggi, Stefania, Mautone, Giuseppe, ... Reginster, Jean-Yves. (2015). Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty. Drugs and Aging. 32(7), pp. 525 - 535. https://doi.org/10.1007/s40266-015-0276-7
Incidence of hip fracture in Brazil and the development of a FRAX model
Zerbini, C. A. F., Szejnfeld, V. L., Abergaria, B. H., McCloskey, Eugene V., Johansson, Helena and Kanis, John A.. (2015). Incidence of hip fracture in Brazil and the development of a FRAX model. Archives of Osteoporosis. 10(1), pp. 1 - 7. https://doi.org/10.1007/s11657-015-0224-5
A systematic review of cost-effectiveness analyses of drugs for postmenopausal osteoporosis
Hiligsmann, Mickaël, Evers, Silvia M., Sedrine, Wafa Ben, Kanis, John A., Ramaekers, Bram, Reginster, Jean Yves, Silverman, S., Wyers, Caroline E. and Boonen, Annelies. (2015). A systematic review of cost-effectiveness analyses of drugs for postmenopausal osteoporosis. PharmacoEconomics. 33(3), pp. 205 - 224. https://doi.org/10.1007/s40273-014-0231-1
Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: Expert consensus statement
Reginster, Jean Yves, Reiter-Niesert, S., Bruyère, O., Berenbaum, F., Brandi, Maria-Luisa, Branco, J., Devogelaer, J.-P., Herrero-Beaumont, G., Kanis, John A., Maggi, S., Maheu, E., Richette, P., Rizzoli, R. and Cooper, C.. (2015). Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: Expert consensus statement. Osteoarthritis and Cartilage. 23(12), pp. 2086 - 2093. https://doi.org/10.1016/j.joca.2015.07.001
Predictive ability of heel quantitative ultrasound for incident fractures: an individual-level meta-analysis
McCloskey, Eugene V., Kanis, John A., Oden, Anders, Harvey, Nicholas C., Bauer, D., Gonzalez-Macias, J., Hans, D., Kaptoge, S., Krieg, Marc Antoine, Kwok, T., Marin, F., Moayyeri, A., Orwoll, E., Gluёr, C. and Johansson, Helena. (2015). Predictive ability of heel quantitative ultrasound for incident fractures: an individual-level meta-analysis. Osteoporosis International. 26(7), pp. 1979 - 1987. https://doi.org/10.1007/s00198-015-3072-7
Prolonged adaptation to a low or high protein diet does not modulate basal muscle protein synthesis rates: A substudy
Hursel, Rick, Martens, Eveline A. P., Gonnissen, Hanne K. J., Hamer, Henrike M., Senden, Joan M., Van Loon, Luc and Westerterp-Plantenga, Margriet S.. (2015). Prolonged adaptation to a low or high protein diet does not modulate basal muscle protein synthesis rates: A substudy. PLoS ONE. 10(9), pp. 1 - 15. https://doi.org/10.1371/journal.pone.0137183
FRAX-based assessment and intervention thresholds - An exploration of thresholds in women aged 50 years and older in the UK
McCloskey, Eugene V., Kanis, John A., Johansson, Helena, Harvey, Nicholas C., Oden, Anders, Cooper, Alun, Cooper, C., Francis, Roger M., Reid, D. M., Marsh, D., Selby, P., Thompson, F., Hewitt, S. and Compston, Juliet E.. (2015). FRAX-based assessment and intervention thresholds - An exploration of thresholds in women aged 50 years and older in the UK. Osteoporosis International. 26(8), pp. 2091 - 2099. https://doi.org/10.1007/s00198-015-3176-0
FRAX and the effect of teriparatide on vertebral and non-vertebral fracture
Harvey, Nicholas C., Kanis, John A., Oden, Anders, Burge, R., Mitlak, B., Johansson, Helena and McCloskey, Eugene V.. (2015). FRAX and the effect of teriparatide on vertebral and non-vertebral fracture. Osteoporosis International. 26(11), pp. 2677 - 2684. https://doi.org/10.1007/s00198-015-3173-3
Can elite athletes benefit from dietary nitrate supplementation?
Jonvik, Kristin L., Nyakayiru, Jean, Van Loon, Luc and Verdijk, Lex B.. (2015). Can elite athletes benefit from dietary nitrate supplementation? Journal of Applied Physiology. 119(6), pp. 759 - 761. https://doi.org/10.1152/japplphysiol.00232.2015
Exercise strategies to optimize glycemic control in type 2 diabetes: A continuing glucose monitoring perspective
van Dijk, Jan Willem and Van Loon, Luc. (2015). Exercise strategies to optimize glycemic control in type 2 diabetes: A continuing glucose monitoring perspective. Diabetes Spectrum. 28(1), pp. 24 - 31. https://doi.org/10.2337/diaspect.28.1.24
Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion
Wall, Benjamin T., Gorissen, Stefan H. M., Pennings, Bart, Koopman, René, Groen, Bart B. L., Verdijk, Lex B. and Van Loon, Luc. (2015). Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion. PLoS ONE. 10(11), pp. 1 - 13. https://doi.org/10.1371/journal.pone.0140903
The clinical use of vitamin D metabolites and their potential developments: A position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
Cianferotti, Luisella, Cricelli, Claudio, Kanis, John A., Nuti, Ranuccio, Reginster, Jean-Yves, Ringe, Johann D., Rizzoli, Rene and Brandi, Maria Luisa. (2015). The clinical use of vitamin D metabolites and their potential developments: A position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Endocrine. 50(1), pp. 12 - 26. https://doi.org/10.1007/s12020-015-0606-x
Hip axis length is a FRAX-and bone density-independent risk factor for hip fracture in women
Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2015). Hip axis length is a FRAX-and bone density-independent risk factor for hip fracture in women. Journal of Clinical Endocrinology and Metabolism. 100(5), pp. 2063 - 2070. https://doi.org/10.1210/jc.2014-4390
Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older
Bischoff-Ferrari, Heike A., Orav, J. E., Kanis, John A., Rizzoli, R., Schlögl, M., Staehelin, H. B., Willett, Walter C. and Dawson-Hughes, B.. (2015). Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Osteoporosis International. 26(12), pp. 2793 - 2802. https://doi.org/10.1007/s00198-015-3194-y
Is the Swedish FRAX model appropriate for Swedish immigrants?
Johansson, Helena, Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene V., Kanis, John A., Harvey, Nicholas C., Karlsson, M. K. and Mellström, Dan. (2015). Is the Swedish FRAX model appropriate for Swedish immigrants? Osteoporosis International. 26(11), pp. 2617 - 2622. https://doi.org/10.1007/s00198-015-3180-4
Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, Olivier, Cooper, Cyrus, Arden, Nigel, Branco, Jaime, Brandi, Maria Luisa, Herrero-Beaumont, Gabriel, Berenbaum, Francis, Dennison, Elaine M., Devogelaer, Jean-Pierre, Hochberg, Marc, Kanis, John A., Laslop, Andrea, McAlindon, Tim, Reiter, Susanne, Richette, Pascal, Rizzoli, Rene and Reginster, Jean-Yves. (2015). Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis. Drugs and Aging. 32(3), pp. 179 - 187. https://doi.org/10.1007/s40266-015-0243-3
Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX
Harvey, Nicholas C., Kanis, John A., Oden, Anders, Nakamura, T., Shiraki, M., Sugimoto, T., Kuroda, T., Johansson, Helena and McCloskey, Eugene V.. (2015). Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX. Osteoporosis International. 26(9), pp. 2347 - 2353. https://doi.org/10.1007/s00198-015-3129-7
Serum 25-hydroxyvitamin D levels: Variability, knowledge gaps, and the concept of a desirable range
El-Hajj Fuleihan, Ghada, Bouillon, Roger, Clarke, Bart, Chakhtoura, Marlene, Cooper, Cyrus, McClung, Michael R. and Singh, Ravinder J.. (2015). Serum 25-hydroxyvitamin D levels: Variability, knowledge gaps, and the concept of a desirable range. Journal of Bone and Mineral Research. 30(7), pp. 1119 - 1133. https://doi.org/10.1002/jbmr.2536
FRAX and fracture prediction without bone mineral density
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Oden, Anders, Leslie, William D. and McCloskey, Eugene. (2015). FRAX and fracture prediction without bone mineral density. Climacteric. 18, pp. 2 - 9. https://doi.org/10.3109/13697137.2015.1092342
Post-prandial protein handling: You are what you just ate
Groen, Bart B. L., Horstman, Astrid M. H., Hamer, Henrike M., De Haan, Michiel, Van Kranenburg, Janneau, Bierau, Jörgen, Poeze, Martijn, Wodzig, Will K. W. H., Rasmussen, Blake B. and van Loon, Luc. (2015). Post-prandial protein handling: You are what you just ate. PLoS ONE. 10(11), pp. 1 - 22. https://doi.org/10.1371/journal.pone.0141582
Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study
Vimaleswaran, Karani S., Cavadino, Alana, Berry, Diane J., Jorde, Rolf, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J. Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, Andrew, Mangino, Massimo, Jablonski, Kathleen A., Nolte, Ilja M., Houston, Denise K., Ahluwalia, Tarunveer Singh, van der Most, Peter J., Pasko, Dorota, Zgaga, Lina, ... Hyppönen, Elina. (2014). Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study. The Lancet Diabetes & Endocrinology. 2(9), pp. 719 - 729. https://doi.org/10.1016/S2213-8587(14)70113-5
The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX
Siggeirsdottir, K., Aspelund, T., Johansson, Helena, Gudmundsson, E. F., Mogensen, B., Jonsson, B. Y., Gudnason, V., McCloskey, Eugene, Oden, Anders, Sigurdsson, G. and Kanis, John A.. (2014). The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX. Osteoporosis International. 25(10), pp. 2445 - 2451. https://doi.org/10.1007/s00198-014-2777-3
Epidemiology and economic burden of osteoporosis in Switzerland
Svedbom, A., Ivergard, M., Hernlund, E., Rizzoli, R. and Kanis, John A.. (2014). Epidemiology and economic burden of osteoporosis in Switzerland. Archives of Osteoporosis. 9, pp. 187 - 187. https://doi.org/10.1007/s11657-014-0187-y
Management of osteoporosis of the oldest old
Rizzoli, R, Branco, J., Brandi, Maria Luisa, Boonen, S., Bruyère, O., Cacoub, P., Cooper, Cyrus, Diez-Perez, A, Duder, J., Fielding, R. A., Harvey, Nicholas C., Hiligsmann, Mickaël, Kanis, John A., Petermans, J., Ringe, J. D., Tsouderos, Y., Weinman, J. and Reginster, Jean Yves. (2014). Management of osteoporosis of the oldest old. Osteoporosis International. 25(11), pp. 2507 - 2529. https://doi.org/10.1007/s00198-014-2755-9
Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures
Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2014). Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures. Osteoporosis International. 25(1), pp. 235 - 241. https://doi.org/10.1007/s00198-013-2460-0
Lumbar spine texture enhances 10-year fracture probability assessment
Leslie, William D., Johansson, Helena, Kanis, John A., Lamy, Olivier, Oden, Anders, McCloskey, Eugene V. and Hans, D.. (2014). Lumbar spine texture enhances 10-year fracture probability assessment. Osteoporosis International. 25(9), pp. 2271 - 2277. https://doi.org/10.1007/s00198-014-2761-y
Value of biomarkers in osteoarthritis: Current status and perspectives
Lotz, M., Martel-Pelletier, Johanne, Christiansen, Claus, Brandi, Maria Luisa, Bruyère, O., Chapurlat, Roland D., Collette, J., Cooper, Cyrus, Giacovelli, G., Kanis, John A., Karsdal, M. A., Kraus, V., Lems, Willem F., Meulenbelt, I., Pelletier, Jean Pierre, Raynauld, J. P., Reiter-Niesert, S., Rizzoli, R., Sandell, L. J., ... Reginster, Jean Yves. (2014). Value of biomarkers in osteoarthritis: Current status and perspectives. Postgraduate Medical Journal. 90(1061), pp. 171 - 178. https://doi.org/10.1136/postgradmedj-2013-203726rep
A meta-analysis of reference markers of bone turnover for prediction of fracture
Johansson, Helena, Oden, Anders, Kanis, John A., McCloskey, Eugene V., Morris, Howard A., Cooper, Cyrus and Vasikaran, Samuel. (2014). A meta-analysis of reference markers of bone turnover for prediction of fracture. Calcified Tissue International. 94(5), pp. 560 - 567. https://doi.org/10.1007/s00223-014-9842-y
Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention study (OSTPRE)
Sund, Reijo, Honkanen, Risto, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John and Kröger, Heikki. (2014). Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention study (OSTPRE). Calcified Tissue International. 95(1), pp. 39 - 45. https://doi.org/10.1007/s00223-014-9860-9
Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific Region
Wu, Chih-Hsing, McCloskey, Eugene V., Lee, Joon Kiong, Itabashi, Akira, Prince, Richard L., Yu, Wei, Li-Yu, Julie, Chionh, Siok Bee, Zhao, Yanling, Shin, Chan Soo, Gunawan, Tirtarahardja, Tsai, Keh-Sung, Chieng, Poon-Ung, Changlai, Sheng-Pin, Chan, Ding-Cheng, Chen, Jung-Fu, Tanner, S. Bobo, Hans, Didier B., Kanis, John A., ... Yang, Rong-Sen. (2014). Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific Region. Journal of Clinical Densitometry. 17(1), pp. 150 - 155. https://doi.org/10.1016/j.jocd.2013.06.002
The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Rizzoli, Rene, Stevenson, John C., Bauer, Jürgen M., Van Loon, Lucas J.C., Walrand, Stéphane, Kanis, John A., Cooper, Cyrus, Brandi, Maria Luisa, Diez-Perez, Adolfo and Reginster, Jean Yves. (2014). The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas. 79(1), pp. 122 - 132. https://doi.org/10.1016/j.maturitas.2014.07.005
Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: Estimations from a disease model
Piscitelli, P., Brandi, M., Cawston, H., Gauthier, A., Kanis, J. A., Compston, J., Borgstrom, F., Cooper, C. and McCloskey, E.. (2014). Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: Estimations from a disease model. Calcified Tissue International. 95(5), pp. 419 - 427. https://doi.org/10.1007/s00223-014-9910-3
An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Bruyère, Olivier, Cooper, Cyrus, Pelletier, Jean-Pierre, Branco, Jaime, Brandi, Maria Luisa, Guillemin, Francis, Hochberg, Marc C., Kanis, John A., Kvien, Tore K., Martel-Pelletier, Johanne, Rizzoli, Rene, Silverman, Stuart and Reginster, Jean-Yves. (2014). An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 44(3), pp. 253 - 263. https://doi.org/10.1016/j.semarthrit.2014.05.014
The application of health technology assessment in osteoporosis
Kanis, John A. and Hiligsmann, Mickaël. (2014). The application of health technology assessment in osteoporosis. Best Practice and Research: Clinical Endocrinology and Metabolism. 28(6), pp. 895 - 910. https://doi.org/10.1016/j.beem.2014.04.001
Goal-directed treatment of osteoporosis in Europe
Kanis, John A., McCloskey, Eugene, Branco, J., Brandi, Maria-Luisa, Dennison, Elaine M., Devogelaer, J.-P., Ferrari, S., Kaufman, J.-M., Papapoulos, S., Reginster, Jean-Yves and Rizzoli, R.. (2014). Goal-directed treatment of osteoporosis in Europe. Osteoporosis International. 25(11), pp. 2533 - 2543. https://doi.org/10.1007/s00198-014-2787-1
Waning predictive value of serum adiponectin for fracture risk in elderly men: MrOS Sweden
Johansson, Helena, Oden, Anders, Karlsson, Magnus, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes and Mellström, Dan. (2014). Waning predictive value of serum adiponectin for fracture risk in elderly men: MrOS Sweden. Osteoporosis International. 25(7), pp. 1831 - 1836. https://doi.org/10.1007/s00198-014-2654-0
Dietary Protein as a Trigger for Metabolic Adaptation
Van Loon, Luc. (2014). Dietary Protein as a Trigger for Metabolic Adaptation. In In R. J. Maughan (Ed.). The Encyclopaedia of Sports Medicine: An IOC Medical Commission Publication pp. 147-155 Wiley-Blackwell.
Challenges for the development of bone-forming agents in Europe
Kanis, John A., Rizzoli, Rene, Cooper, Cyrus and Reginster, Jean-Yves. (2014). Challenges for the development of bone-forming agents in Europe. Calcified Tissue International. 94(5), pp. 469 - 473. https://doi.org/10.1007/s00223-014-9844-9
The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans
Burd, N., Cermak, N., Kouw, Imre W. K., Gorissen, Stefan H. M., Gijsen, Annemie P. and Van Loon, Luc. (2014). The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans. Journal of Applied Physiology. 117(11), pp. 1363 - 1370. https://doi.org/10.1152/japplphysiol.00411.2014
Low holotranscobalamin and cobalamins predict incident fractures in elderly men: The MrOS Sweden
Lewerin, C. Lewerin, Nilsson-Ehle, H., Jacobsson, S., Johansson, Helena, Sundh, V., Karlsson, Magnus, Ljunggren, Östen, Lorentzon, Mattias, Kanis, John A., Lerner, Ulf H., Cummings, Steven R., Ohlsson, Claes and Mellström, Dan. (2014). Low holotranscobalamin and cobalamins predict incident fractures in elderly men: The MrOS Sweden. Osteoporosis International. 25(1), pp. 131 - 140. https://doi.org/10.1007/s00198-013-2527-y
A meta-analysis of the association of fracture risk and body mass index in women
Johansson, Helena, Kanis, John A., Oden, Anders, McCloskey, Eugene, Chapurlat, Roland D., Christiansen, Claus, Cummings, Steven R., Diez-Perez, A, Eisman, John A., Fujiwara, S., Glüer, C. C., Goltzman, David, Hans, D., Khaw, Kay Tee, Krieg, Marc Antoine, Kröger, Heikki, LaCroix, A. Z., Lau, E., Leslie, William D., ... Zillikens, M. Carola. (2014). A meta-analysis of the association of fracture risk and body mass index in women. Journal of Bone and Mineral Research. 29(1), pp. 223 - 233. https://doi.org/10.1002/jbmr.2017
The effect of latitude on the risk and seasonal variation in hip fracture in Sweden
Oden, Anders, Kanis, John A., McCloskey, Eugene V. and Johansson, Helena. (2014). The effect of latitude on the risk and seasonal variation in hip fracture in Sweden. Journal of Bone and Mineral Research. 29(10), pp. 2217 - 2223. https://doi.org/10.1002/jbmr.2250
A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Hiligsmann, Mickaël, Cooper, Cyrus, Guillemin, Francis, Hochberg, Marc C., Tugwell, Peter, Arden, Nigel, Berenbaum, Francis, Boers, Maarten, Boonen, Annelies, Branco, Jaime C., Maria-Luisa, Brandi, Bruyère, Olivier, Gasparik, Andrea Ildiko, Kanis, John A., Kvien, Tore K., Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Pinedo-Villanueva, Rafael, Pinto, Daniel, ... Reginster, Jean-Yves. (2014). A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 44(3), pp. 271 - 282. https://doi.org/10.1016/j.semarthrit.2014.06.005
Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
Moayyeri, Alireza, Hsu, Yi-Hsiang, Karasik, David, Estrada, Karol, Xiao, Su-Mei, Nielson, Carrie, Srikanth, Priya, Giroux, Sylvie, Wilson, Scott G., Zheng, Hou-Feng, Smith, Albert V., Pye, Stephen R., Leo, Paul J., Teumer, Alexander, Hwang, Joo-Yeon, Ohlsson, Claes, McGuigan, Fiona, Minster, Ryan L., Hayward, Caroline, ... Kaptoge, Stephen K.. (2014). Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Human Molecular Genetics. 23(11), pp. 3054 - 3068. https://doi.org/10.1093/hmg/ddt675
Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm
Kim, K., Svedbom, A., Luo, X., Sutradhar, S. and Kanis, John A.. (2014). Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm. Osteoporosis International. 25(1), pp. 325 - 337. https://doi.org/10.1007/s00198-013-2521-4
Worldwide uptake of FRAX
Kanis, John A., Johansson, Helena, Oden, Anders, Cooper, Cyrus, McCloskey, Eugene E. V., Epidemiology and Quality of Life Working Group of IOF, and Epidemiology and Quality of Life Working Group of IOF. (2014). Worldwide uptake of FRAX. Archives of Osteoporosis. 9(1), pp. 1 - 10. https://doi.org/10.1007/s11657-013-0166-8
The effect of a six-month resistance-type exercise training program on the course of high sensitive cardiac troponin T levels in (pre)frail elderly
Van Der Linden, Noreen, Tieland, Michael, Klinkenberg, Lieke J. J., Verdijk, Lex B., de Groot, Lisette C. P. G. M., Van Loon, Lucas, Van Dieijen-Visser, Marja P. and Meex, Steven J. R.. (2014). The effect of a six-month resistance-type exercise training program on the course of high sensitive cardiac troponin T levels in (pre)frail elderly. International Journal of Cardiology. 175(2), pp. 374 - 375. https://doi.org/10.1016/j.ijcard.2014.05.017
Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not frax independent risk factors for fracture
Leslie, William D., Orwoll, E., Nielson, Carrie M., Morin, Suzanne N., Majumdar, S. R., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2014). Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not frax independent risk factors for fracture. Journal of Bone and Mineral Research. 29(S1), pp. 2511 - 2519. https://doi.org/10.1002/jbmr.2280
Gaucher disease and bone manifestations
Marcucci, Gemma, Zimran, Ari, Bembi, Bruno, Kanis, John, Reginster, Jean-Yves, Rizzoli, Rene, Cooper, Cyrus and Brandi, Maria Luisa. (2014). Gaucher disease and bone manifestations. Calcified Tissue International. 95(6), pp. 477 - 494. https://doi.org/10.1007/s00223-014-9923-y
Trabecular bone score: A noninvasive analytical method based upon the DXA image
Silva, Barbara C., Leslie, William D., Resch, Heinrich, Lamy, Olivier, Lesnyak, Olga, Binkley, Neil, McCloskey, Eugene V., Kanis, John A. and Bilezikian, John P.. (2014). Trabecular bone score: A noninvasive analytical method based upon the DXA image. Journal of Bone and Mineral Research. 29(3), pp. 518 - 530. https://doi.org/10.1002/jbmr.2176
Can change in FRAX score be used to "treat to target"? A population-based cohort study
Leslie, William D., Majumdar, S. R., Lix, Lisa, Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2014). Can change in FRAX score be used to "treat to target"? A population-based cohort study. Journal of Bone and Mineral Research. 29(5), pp. 1074 - 1080. https://doi.org/10.1002/jbmr.2151
Kracht- en duurinspanning verbeteren 24-uurs bloedglucosehomeostase bij personen met een verminderde glucosetolerantie bij patiënten met type 2 diabetes
Jan Willem van Dijk, Ralph J F Manders, Kyra Tummers, A G Bonomi, Coen D A Stehouwer, Fred Hartgens and Luc Van Loon. (2013). Kracht- en duurinspanning verbeteren 24-uurs bloedglucosehomeostase bij personen met een verminderde glucosetolerantie bij patiënten met type 2 diabetes. Nederlands Tijdschrift voor Diabetologie. 11(2), pp. 52-53. https://doi.org/10.1007/s12467-013-0019-5
Voeding bij intensieve sportbeoefening
Van Loon, L., van Erp-Baart, A. M. J. and Saris, Wim H. M. (2013). Voeding bij intensieve sportbeoefening. In In Majorie Former (Ed.). Informatorium Voeding en Dietetiek - Voedingsleer pp. 547-568 Springer.
Updated fracture incidence rates for the Italian version of FRAX®
Piscitelli, P., Chitano, G., Johannson, Henning R., Brandi, Maria Luisa, Kanis, John A. and Black, Deborah. (2013). Updated fracture incidence rates for the Italian version of FRAX®. Osteoporosis International. 24(3), pp. 859 - 866. https://doi.org/10.1007/s00198-012-2021-y
Treatment of osteoporosis in men
Kaufman, J-M, Reginster, J-Y, Boonen, S., Brandi, M. L., Cooper, Cyrus, Dere, W., Devogelaer, J. P., Diez-Perez, A, Kanis, John A., McCloskey, Eugene, Mitlak, B., Orwoll, E, Ringe, J. D., Weryha, G. and Rizzoli, R. (2013). Treatment of osteoporosis in men. Bone. 53(1), pp. 134 - 144. https://doi.org/10.1016/j.bone.2012.11.018
Incidence of hip fracture in Barranquilla, Colombia, and the development of a Colombian FRAX model
Jaller, J. J., Jaller, J. J., Lechuga, J. A., Navarro, E., Johansson, Helena and Kanis, John. (2013). Incidence of hip fracture in Barranquilla, Colombia, and the development of a Colombian FRAX model. Calcified Tissue International. 93(1), pp. 15 - 22. https://doi.org/10.1007/s00223-013-9717-7
Value of biomarkers in osteoarthritis: Current status and perspectives
Lotz, M., Martel-Pelletier, Johanne, Christiansen, Claus, Brandi, Maria-Luisa, Bruyère, O., Chapurlat, Roland D., Collette, J., Cooper, Cyrus, Giacovelli, G., Kanis, John A., Karsdal, M. A., Kraus, V., Lems, Willem F., Meulenbelt, I., Pelletier, Jean-Pierre, Raynauld, J.-P., Reiter-Niesert, S., Rizzoli, R., Sandell, L. J., ... Reginster, Jean-Yves. (2013). Value of biomarkers in osteoarthritis: Current status and perspectives. Annals of the Rheumatic Diseases. 72(11), pp. 1756 - 1763. https://doi.org/10.1136/annrheumdis-2013-203726
Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013
Compston, J., Bowring, C., Cooper, A., Cooper, C., Davies, C., Francis, R., Kanis, J. A., Marsh, D., McCloskey, E. V., Reid, D. M. and Selby, P.. (2013). Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013. Maturitas. 75(4), pp. 392 - 396. https://doi.org/10.1016/j.maturitas.2013.05.013
Quality of life in sarcopenia and frailty
Rizzoli, Rene, Reginster, Jean-Yves, Arnal, Jean-Francois, Bautmans, Ivan, Beaudart, Charlotte, Bischoff-Ferrari, Heike, Biver, Emmanuel, Boonen, Steven, Brandi, Maria-Luisa, Chines, Arkadi, Cooper, Cyrus, Epstein, Sol, Fielding, Roger A., Goodpaster, Bret, Kanis, John A., Kaufman, J., Laslop, A., Malafarina, Vincenzo, Mañas, Leocadio Rodriguez, ... Bruyère, O.. (2013). Quality of life in sarcopenia and frailty. Calcified Tissue International. 93(2), pp. 101 - 120. https://doi.org/10.1007/s00223-013-9758-y
Vitamin D supplementation in elderly or postmenopausal women: A 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Rizzoli, R., Boonen, S., Brandi, Maria-Luisa, Bruyère, O., Cooper, Cyrus, Kanis, John A., Kaufman, J.-M., Ringe, J. D., Weryha, G. and Reginster, Jean Yves. (2013). Vitamin D supplementation in elderly or postmenopausal women: A 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Current Medical Research and Opinion. 29(4), pp. 305 - 313. https://doi.org/10.1185/03007995.2013.766162
Incidence of hip fracture in Romania and the development of a Romanian FRAX model
Grigorie, Daniel, Sucaliuc, Alina, Johansson, Helena, Kanis, John A. and McCloskey, Eugene. (2013). Incidence of hip fracture in Romania and the development of a Romanian FRAX model. Calcified Tissue International. 92(5), pp. 429 - 436. https://doi.org/10.1007/s00223-013-9697-7
Assessing the impact of osteoporosis on the burden of hip fractures
Oden, Anders, McCloskey, Eugene V., Johansson, Helena and Kanis, John A.. (2013). Assessing the impact of osteoporosis on the burden of hip fractures. Calcified Tissue International. 92(1), pp. 42 - 49. https://doi.org/10.1007/s00223-012-9666-6
The role of amino acids in skeletal muscle adaptation to exercise
Aguirre, Nick, Van Loon, Lucas and Baar, Keith. (2013). The role of amino acids in skeletal muscle adaptation to exercise. In In E. Isolauri, P.M. Sherman and W. A. Walker (Ed.). Nestle Nutrition Institute workshop series pp. 85 - 102 S. Karger AG. https://doi.org/10.1159/000350261
Health technology assessment in osteoporosis
Hiligsmann, Mickaël, Kanis, John A., Compston, Juliet, Cooper, Cyrus, Flamion, Bruno, Bergmann, Pierre, Body, Jean-Jaques, Boonen, Steven, Bruyère, Olivier, Devogelaer, Jean-Pierre, Goemaere, Stefan, Kaufman, Jean-Marc, Rozenberg, Serge and Reginster, Jean-Yves. (2013). Health technology assessment in osteoporosis. Calcified Tissue International. 93(1), pp. 1 - 14. https://doi.org/10.1007/s00223-013-9724-8
FRAX-based intervention and assessment thresholds for osteoporosis in Romania
Grigorie, Daniel, Sucaliuc, Alina, Johansson, Helena, Kanis, John A. and McCloskey, Eugene. (2013). FRAX-based intervention and assessment thresholds for osteoporosis in Romania. Archives of Osteoporosis. 8(2017-02-01), pp. 1 - 5. https://doi.org/10.1007/s11657-013-0164-x
Selection of women aged 50-64yr for bone density measurement
Leslie, William D., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2013). Selection of women aged 50-64yr for bone density measurement. Journal of Clinical Densitometry. 16(4), pp. 570 - 578. https://doi.org/10.1016/j.jocd.2013.01.004
Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Hiligsmann, Mickaël, Cooper, Cyrus, Arden, Nigel, Boers, Maarten, Branco, Jaime C., Brandi, Maria Luisa, Bruyère, Olivier, Guillemin, Francis, Hochberg, Marc C., Hunter, David J., Kanis, John A., Kvien, Tore K., Laslop, Andrea, Pelletier, Jean-Pierre, Pinto, Daniel, Reiter-Niesert, Susanne, Rizzoli, Rene, Rovati, Lucio C., Severens, Johan L., ... Reginster, Jean-Yves. (2013). Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 43(3), pp. 303 - 313. https://doi.org/10.1016/j.semarthrit.2013.07.003
Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake
Nabuurs, C. I., Choe, C. U., Veltien, A., Kan, H. E., Van Loon, Luc, Rodenburg, R. J. T., Matschke, J., Wieringa, B., Kemp, G. J., Isbrandt, D. and Heerschap, A.. (2013). Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake. Journal of Physiology. 591(2), pp. 571 - 592. https://doi.org/10.1113/jphysiol.2012.241760
Osteoporosis in the European Union: A compendium of country-specific reports
Svedbom, A., Hernlund, E., Ivergård, M., Compston, Juliet E., Cooper, Cyrus, Stenmark, J., McCloskey, Eugene V., Jönsson, Bengt, Kanis, John A., The EU review panel of the IOF, and The EU review panel of the IOF. (2013). Osteoporosis in the European Union: A compendium of country-specific reports. Archives of Osteoporosis. 8(1-2), pp. 1 - 218. https://doi.org/10.1007/s11657-013-0137-0
How to define responders in osteoarthritis
Cooper, Cyrus, Adachi, Jonathan D., Bardin, Thomas, Berenbaum, Francis, Flamion, Bruno, Jonsson, Helgi, Kanis, John A., Pelousse, Franz, Lems, Willem F., Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Reiter, Susanne, Reginster, Jean-Yves, Rizzoli, Rene and Bruyère, Olivier. (2013). How to define responders in osteoarthritis. Current Medical Research and Opinion. 29(6), pp. 719 - 729. https://doi.org/10.1185/03007995.2013.792793
The osteoporosis treatment gap in Romania
Kanis, John, Hernlund, E., Svedbom, Axel, Ivergãrd, M. and Grigorie, Daniel. (2013). The osteoporosis treatment gap in Romania. Acta Endocrinologica. 9(4), pp. 509 - 514. https://doi.org/10.4183/aeb.2013.509
European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, John A., McCloskey, Eugene V., Johansson, Helena, Cooper, Cyrus, Rizzoli, R. and Reginster, Jean Yves. (2013). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 24(1), pp. 23 - 57. https://doi.org/10.1007/s00198-012-2074-y
Intervention thresholds for denosumab in the UK using a FRAX®-based cost-effectiveness analysis
Ström, O., Jönsson, Bengt and Kanis, John A.. (2013). Intervention thresholds for denosumab in the UK using a FRAX®-based cost-effectiveness analysis. Osteoporosis International. 24(4), pp. 1491 - 1502. https://doi.org/10.1007/s00198-012-2115-6
Tools in the assessment of sarcopenia
Cooper, C., Fielding, R., Visser, M., Van Loon, L. J., Rolland, Y., Orwoll, E., Reid, K., Boonen, S., Dere, W., Epstein, S., Mitlak, B., Tsouderos, Y., Sayer, A. A., Rizzoli, R., Reginster, J. Y. and Kanis, J. A.. (2013). Tools in the assessment of sarcopenia. Calcified Tissue International. 93(3), pp. 201 - 210. https://doi.org/10.1007/s00223-013-9757-z
Elderly men and women benefit equally from prolonged resistance-type exercise training
Leenders, Marika, Verdijk, Lex B., van der Hoeven, Letty, Van Kranenburg, Janneau, Nilwik, Rachel and Van Loon, Luc. (2013). Elderly men and women benefit equally from prolonged resistance-type exercise training. Journals of Gerontology: Series A Biological Sciences and Medical Sciences. 68(7), pp. 769 - 779. https://doi.org/10.1093/gerona/gls241
Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee
Dempster, David W., Compston, Juliet E., Drezner, Marc K., Glorieux, Francis H., Kanis, John A., Malluche, Hartmut, Meunier, Pierre J., Ott, Susan M., Recker, Robert R. and Parfitt, A. Michael. (2013). Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee. Journal of Bone and Mineral Research. 28(1), pp. 2 - 17. https://doi.org/10.1002/jbmr.1805
Validity and Reliability of Tools to Measure Muscle Mass, Strength, and Physical Performance in Community-Dwelling Older People: A Systematic Review
Mijnarends, Donja M., Meijers, Judith M. M., Halfens, Ruud J. G., Borg, Sovianne Ter, Luiking, Yvette C., Verlaan, Sjors, Schoberer, Daniela, Cruz-Jentoft, Alfonso J., Van Loon, Luc and Schols, Jos M. G. A.. (2013). Validity and Reliability of Tools to Measure Muscle Mass, Strength, and Physical Performance in Community-Dwelling Older People: A Systematic Review. Journal of the American Medical Directors Association. 14(3), pp. 170 - 178. https://doi.org/10.1016/j.jamda.2012.10.009
SCOPE: A scorecard for osteoporosis in Europe
Kanis, John A., Borgström, F., Compston, Juliet E., Dreinhöfer, K., Nolte, E., Jonsson, L., Le, Willem F., McCloskey, Eugene, Rizzoli, R. and Stenmark, J.. (2013). SCOPE: A scorecard for osteoporosis in Europe. Archives of Osteoporosis. 8(42767), pp. 1 - 63. https://doi.org/10.1007/s11657-013-0144-1
Substantial differences between organ and muscle specific tracer incorporation rates in a lactating dairy cow
Burd, N, Hamer, Henrike M., Pennings, Bart, Pellikaan, Wilbert F., Senden, Joan M., Gijsen, Annemie P. and Van Loon, Luc. (2013). Substantial differences between organ and muscle specific tracer incorporation rates in a lactating dairy cow. PLoS ONE. 8(6), pp. 1 - 10. https://doi.org/10.1371/journal.pone.0068109
Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: A randomized trial
Klinkenberg, Lieke J. J., Res, Peter T., Haenen, Guido R., Bast, Aalt, Van Loon, Luc, Van Dieijen-Visser, Marja P. and Meex, Steven J. R.. (2013). Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: A randomized trial. PLoS ONE. 8(11), pp. 1 - 6. https://doi.org/10.1371/journal.pone.0079280
Inflammatory bowel disease and the risk of fracture after controlling for FRAX
Targownik, Laura E., Bernstein, Charles N., Nugent, Zoann, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John A. and Leslie, William D.. (2013). Inflammatory bowel disease and the risk of fracture after controlling for FRAX. Journal of Bone and Mineral Research. 28(5), pp. 1007 - 1013. https://doi.org/10.1002/jbmr.1848
Osteoporosis in the European Union: Medical management, epidemiology and economic burden: A report prepared in collaboration with the International Osteoporosis Foundation IOF and the European Federation of Pharmaceutical Industry Associations EFPIA
Hernlund, E., Svedbom, A., Ivergård, M., Compston, Juliet E., Cooper, Cyrus, Stenmark, J., McCloskey, Eugene V., Jönsson, Bengt and Kanis, John A.. (2013). Osteoporosis in the European Union: Medical management, epidemiology and economic burden: A report prepared in collaboration with the International Osteoporosis Foundation IOF and the European Federation of Pharmaceutical Industry Associations EFPIA. Archives of Osteoporosis. 8(1-2), pp. 1 - 115. https://doi.org/10.1007/s11657-013-0136-1
Standardising the descriptive epidemiology of osteoporosis: Recommendations from the Epidemiology and Quality of Life Working Group of IOF
Kanis, John A., Adachi, Jonathan D., Cooper, Cyrus, Clark, P., Cummings, Steven R., Diaz-Curiel, M., Harvey, Nicholas C., Hiligsmann, Mickaël, Papaioannou, A., Pierroz, D. D., Silverman, S. L. and Szulc, P.. (2013). Standardising the descriptive epidemiology of osteoporosis: Recommendations from the Epidemiology and Quality of Life Working Group of IOF. Osteoporosis International. 24(11), pp. 2763 - 2764. https://doi.org/10.1007/s00198-013-2413-7
Development and application of FRAX in the management of osteoporosis in Ireland
McGowan, B., Kanis, John A., Johansson, Helena, Silke, C. and Whelan, B.. (2013). Development and application of FRAX in the management of osteoporosis in Ireland. Archives of Osteoporosis. 8(2017-02-01), pp. 1 - 6. https://doi.org/10.1007/s11657-013-0146-z
What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?
Pelletier, Jean Pierre, Cooper, Cyrus, Peterfy, C., Reginster, Jean Yves, Brandi, Maria Luisa, Bruyère, O., Chapurlat, Roland D., Cicuttini, Flavia, Conaghan, P. G., Doherty, M., Genant, H., Giacovelli, G., Hochberg, Marc, Hunter, David J., Kanis, John A., Kloppenburg, M., Laredo, J. D., McAlindon, T., Nevitt, M., ... Guermazi, A.. (2013). What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis? Annals of the Rheumatic Diseases. 72(10), pp. 1594 - 1604. https://doi.org/10.1136/annrheumdis-2013-203631
Limits of Human Endurance
Van Loon, Luc and Meeusen, Romain. (2012). Limits of Human Endurance S. Karger AG.
Nutritional approaches to treating sarcopenia
Paddon-Jones, Douglas and van Loon, Luc. (2012). Nutritional approaches to treating sarcopenia. In In Cruz-Jentoft, Alfonso J. and Morley, John E. (Ed.). Sarcopenia pp. 275-295 Wiley-Blackwell.
Assessment of health claims in the field of bone: A view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Bruyère, O., Rizzoli, R, Coxam, V., Avouac, B., Chevalier, T., Fabien-Soulé, V., Kanis, John A., Kaufman, J.-M., Tsouderos, Y. and Reginster, Jean-Yves. (2012). Assessment of health claims in the field of bone: A view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporosis International. 23(1), pp. 193 - 199. https://doi.org/10.1007/s00198-011-1561-x
Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model
Stepan, Jan J., Vaculik, Jan, Pavelka, Karel, Zofka, Jan, Johansson, Helena and Kanis, John A.. (2012). Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model. Calcified Tissue International. 90(5), pp. 365 - 372. https://doi.org/10.1007/s00223-012-9582-9
Implications for fracture healing of current and new osteoporosis treatments: An ESCEO consensus paper
Goldhahn, J., Féron, J. M., Kanis, J., Papapoulos, S., Reginster, J-Y., Rizzoli, R., Dere, W., Mitlak, B., Tsouderos, Y. and Boonen, S.. (2012). Implications for fracture healing of current and new osteoporosis treatments: An ESCEO consensus paper. Calcified Tissue International. 90(5), pp. 343 - 353. https://doi.org/10.1007/s00223-012-9587-4
A systematic review of hip fracture incidence and probability of fracture worldwide
Kanis, John A., Oden, Anders, McCloskey, Eugene V., Johansson, Helena, Wahl, D. A. and Cooper, Cyrus. (2012). A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis International. 23(9), pp. 2239 - 2256. https://doi.org/10.1007/s00198-012-1964-3
Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk?
Klinkenberg, Lieke J. J., Res, Peter T., Van Loon, Lucas, Van Dieijen-Visser, Marja P. and Meex, Steven J. R.. (2012). Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk? International Journal of Cardiology. 158(1), pp. 129 - 131. https://doi.org/10.1016/j.ijcard.2012.04.050
Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden
Johansson, Helena Johansson, Oden, Anders, Kanis, John A., McCloskey, Eugene, Lorentzon, Mattias, Ljunggren, Östen, Karlsson, Magnus, Thorsby, P. M., Tivesten, A., Barrett-Connor, Elizabeth, Ohlsson, Claes and Mellström, Dan. (2012). Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden. Osteoporosis International. 23(3), pp. 991 - 999. https://doi.org/10.1007/s00198-011-1809-5
Long-term treatment of osteoporosis in postmenopausal women: A review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
Cooper, Cyrus, Reginster, Jean-Yves, Cortet, B., Diaz-Curiel, M., Lorenc, R. S., Kanis, John A. and Rizzoli, R.. (2012). Long-term treatment of osteoporosis in postmenopausal women: A review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Current Medical Research and Opinion. 28(3), pp. 475 - 491. https://doi.org/10.1185/03007995.2012.663750
Does osteoporosis therapy invalidate FRAX for fracture prediction?
Leslie, William D., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). Does osteoporosis therapy invalidate FRAX for fracture prediction? Journal of Bone and Mineral Research. 27(6), pp. 1243 - 1251. https://doi.org/10.1002/jbmr.1582
Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland
Lippuner, K., Johansson, Helena, Borgström, F., Kanis, John A. and Rizzoli, R.. (2012). Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland. Osteoporosis International. 23(11), pp. 2579 - 2589. https://doi.org/10.1007/s00198-011-1869-6
Antidepressant medications and osteoporosis
Rizzoli, R., Cooper, C., Reginster, Jean Yves, Abrahamsen, Bo, Adachi, Jonathan, Brandi, Maria Luisa, Bruyère, O., Compston, Juliet E., Ducy, P., Ferrari, S., Harvey, Nicholas C., Kanis, John A., Karsenty, G., Laslop, A., Rabenda, V. and Vestergaard, P.. (2012). Antidepressant medications and osteoporosis. Bone. 51(3), pp. 606 - 613. https://doi.org/10.1016/j.bone.2012.05.018
Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: Estimations from a disease model
Cawston, H., Maravic, M., Fardellone, P., Gauthier, A., Kanis, John A., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2012). Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: Estimations from a disease model. Archives of Osteoporosis. 7(2017-02-01), pp. 237 - 246. https://doi.org/10.1007/s11657-012-0102-3
A comparative study of using non-hip bone density inputs with FRAX®
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). A comparative study of using non-hip bone density inputs with FRAX®. Osteoporosis International. 23(3), pp. 853 - 860. https://doi.org/10.1007/s00198-011-1814-8
Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Senocak, M., Johansson, Helena and Kanis, John A.. (2012). Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study. Osteoporosis International. 23(3), pp. 949 - 955. https://doi.org/10.1007/s00198-011-1655-5
High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS) Sweden
Johansson, Helena, Oden, Anders, Lerner, Ulf H., Jutberger, Hans, Lorentzon, Mattias, Barrett-Connor, Elizabeth, Karlsson, Magnus, Ljunggren, Östen, Smith, Ulf, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes and Mellstrom, Dan. (2012). High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS) Sweden. Journal of Bone and Mineral Research. 27(6), pp. 1390 - 1396. https://doi.org/10.1002/jbmr.1591
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
Lim, Stephen S., Vos, Theo, Flaxman, Abraham D., Danaei, Goodarz, Shibuya, Kenji, Adair-Rohani, Heather, AlMazroa, Mohammad A., Amann, Markus, Anderson, H. Ross, Andrews, Kathryn G., Aryee, Martin, Atkinson, Charles, Bacchus, Loraine J., Bahalim, Adil N., Balakrishnan, Kalpana, Balmes, John, Barker-Collo, Suzanne, Baxter, Amanda, Bell, Michelle L., ... Ezzati, Majid. (2012). A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 380, pp. 2224 - 2260. https://doi.org/10.1016/S0140-6736(12)61766-8
Fracture risk assessment without bone density measurement in routine clinical practice
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). Fracture risk assessment without bone density measurement in routine clinical practice. Osteoporosis International. 23(1), pp. 75 - 85. https://doi.org/10.1007/s00198-011-1747-2
A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis
Lekamwasam, S., Adachi, Jonathan D., Agnusdei, D., Bilezikian, J. P., Boonen, S., Borgström, F., Cooper, Cyrus, Diez-Perez, A., Eastell, Richard, Hofbauer, L. C., Kanis, John A., Langdahl, B. L., Lesnyak, Olga, Lorenc, R. S., McCloskey, Eugene, Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, Stuart H., ... Compston, Juliet E.. (2012). A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. Osteoporosis International. 23(9), pp. 2257 - 2276. https://doi.org/10.1007/s00198-012-1958-1
FRAX® with and without bone mineral density
Kanis, John A., McCloskey, Eugene, Johansson, Helena, Oden, Anders and Leslie, William D.. (2012). FRAX® with and without bone mineral density. Calcified Tissue International. 90(1), pp. 1 - 13. https://doi.org/10.1007/s00223-011-9544-7
Epidemiology of fracture in the Russian Federation and the development of a FRAX model
Lesnyak, Olga, Ershova, Olga, Belova, Ksenia, Gladkova, Elena, Sinitsina, Olga, Ganert, Olga, Romanova, Marina, Khodirev, Vitalij, Johansson, Helena, McCloskey, Eugene and Kanis, John A.. (2012). Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Archives of Osteoporosis. 7(2017-02-01), pp. 67 - 73. https://doi.org/10.1007/s11657-012-0082-3
Pitfalls in the external validation of FRAX
Kanis, John A., Oden, Anders, Johansson, Helena and McCloskey, Eugene. (2012). Pitfalls in the external validation of FRAX. Osteoporosis International. 23(2), pp. 423 - 431. https://doi.org/10.1007/s00198-011-1846-0
The single biopsy approach is reliable for the measurement of muscle protein synthesis rates in vivo in older men
Burd, N., Pennings, Bart, Groen, Bart B. L., Gijsen, Annemie P., Senden, Joan M. and Van Loon, Luc. (2012). The single biopsy approach is reliable for the measurement of muscle protein synthesis rates in vivo in older men. Journal of Applied Physiology. 113(6), pp. 896 - 902. https://doi.org/10.1152/japplphysiol.00513.2012
Inspanningstherapie bij type 2 diabetes: is dagelijkse inspanning noodzakelijk om glycemische controle te optimaliseren?
van Dijk, Jan W., Tummers, Kyra, Stehouwer, Coen D.A., Hartgens, Fred and van Loon, Luc. (2012). Inspanningstherapie bij type 2 diabetes: is dagelijkse inspanning noodzakelijk om glycemische controle te optimaliseren? Nederlands Tijdschrift voor Diabetologie. 10(2), pp. 60 - 61. https://doi.org/10.1007/s12467-012-0021-3
Burden of postmenopausal osteoporosis in Germany: Estimations from a disease model
Gauthier, A., Kanis, John A., Jiang, Yling, Dreinhöfer, K., Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2012). Burden of postmenopausal osteoporosis in Germany: Estimations from a disease model. Archives of Osteoporosis. 7(2017-02-01), pp. 209 - 218. https://doi.org/10.1007/s11657-012-0099-7
High fracture probability with FRAX® usually indicates densitometric osteoporosis: Implications for clinical practice
Leslie, William D., Majumdar, S. R., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2012). High fracture probability with FRAX® usually indicates densitometric osteoporosis: Implications for clinical practice. Osteoporosis International. 23(1), pp. 391 - 397. https://doi.org/10.1007/s00198-011-1592-3
Potential extensions of the US FRAX algorithm
Melton, Lisa Joseph, Atkinson, Elizabeth J., Achenbach, Sara J., Kanis, John A., Therneau, Terry M., Johansson, Helena, Khosla, Sundeep and Amin, Shreyasee. (2012). Potential extensions of the US FRAX algorithm. Journal of Osteoporosis. 2012, pp. 1 - 8. https://doi.org/10.1155/2012/528790
A reappraisal of generic bisphosphonates in osteoporosis
Kanis, John A., Reginster, Jean Yves, Kaufman, J.-M., Ringe, J.-D., Adachi, Jonathan D., Hiligsmann, Mickaël, Rizzoli, R. and Cooper, Cyrus. (2012). A reappraisal of generic bisphosphonates in osteoporosis. Osteoporosis International. 23(1), pp. 213 - 221. https://doi.org/10.1007/s00198-011-1796-6
FRAX underestimates fracture risk in patients with diabetes
Giangregorio, Lora M., Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). FRAX underestimates fracture risk in patients with diabetes. Journal of Bone and Mineral Research. 27(2), pp. 301 - 308. https://doi.org/10.1002/jbmr.556
FRAX® probabilities and risk of major osteoporotic fracture in France
Couris, C. M., Chapurlat, Roland D., Kanis, John A., Johansson, Helena, Burlet, N., Delmas, P. D. and Schott, A. M.. (2012). FRAX® probabilities and risk of major osteoporotic fracture in France. Osteoporosis International. 23(9), pp. 2321 - 2327. https://doi.org/10.1007/s00198-011-1883-8
Management of glucocorticoid-induced osteoporosis
Rizzoli, R., Adachi, J. D., Cooper, C., Dere, W., Devogelaer, J. P., Diez-Perez, A., Kanis, J. A., Laslop, A., Mitlak, B., Papapoulos, S., Ralston, S., Reiter, S., Werhya, G. and Reginster, J. Y.. (2012). Management of glucocorticoid-induced osteoporosis. Calcified Tissue International. 91(4), pp. 225 - 243. https://doi.org/10.1007/s00223-012-9630-5
Vitamin D with calcium reduces mortality: Patient level pooled analysis of 70,528 patients from eight major vitamin D trials
Rejnmark, Lars, Avenell, Alison, Masud, Tahir, Anderson, Frazer, Meyer, Haakon E., Sanders, Kerrie M., Salovaara, Kari, Cooper, Cyrus, Smith, Helen E., Jacobs, Elizabeth T., Torgerson, David, Jackson, Rebecca D., Manson, JoAnn E., Brixon, Kim, Mosekilde, Leif, Robbins, John A., Francis, Roger M. and Abrahamsen, Bo. (2012). Vitamin D with calcium reduces mortality: Patient level pooled analysis of 70,528 patients from eight major vitamin D trials. Journal of Clinical Endocrinology and Metabolism. 97(8), pp. 2670 - 2681. https://doi.org/10.1210/jc.2011-3328
The impact of a FRAX-based intervention threshold in Turkey: The FRAX-TURK study
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Johansson, Helena, McCloskey, Eugene, Kanis, John A., Turkish Osteoporosis Society, and Turkish Osteoporosis Society. (2012). The impact of a FRAX-based intervention threshold in Turkey: The FRAX-TURK study. Archives of Osteoporosis. 7(2017-02-01), pp. 229 - 235. https://doi.org/10.1007/s11657-012-0101-4
Type 2 diabetes and bone
Leslie, William D., Rubin, Mishaela R., Schwartz, Ann V. and Kanis, John A.. (2012). Type 2 diabetes and bone. Journal of Bone and Mineral Research. 27(11), pp. 2231 - 2237. https://doi.org/10.1002/jbmr.1759
FRAX updates 2012
McCloskey, Eugene V. and Kanis, John A.. (2012). FRAX updates 2012. Current Opinion in Rheumatology. 24(5), pp. 554 - 560. https://doi.org/10.1097/BOR.0b013e328356d2f5
A comparison of case-finding strategies in the UK for the management of hip fractures
Johansson, Helena, Kanis, John A., Oden, Anders, Compston, Juliet E. and McCloskey, Eugene. (2012). A comparison of case-finding strategies in the UK for the management of hip fractures. Osteoporosis International. 23(3), pp. 907 - 915. https://doi.org/10.1007/s00198-011-1864-y
The potential impact of the National Osteoporosis Foundation guidance on treatment eligibility in the USA: An update in NHANES 2005-2008
Dawson-Hughes, Bess, Looker, A. C., Tosteson, Anna N. A., Johansson, Helena, Kanis, John A. and Melton, Lisa. (2012). The potential impact of the National Osteoporosis Foundation guidance on treatment eligibility in the USA: An update in NHANES 2005-2008. Osteoporosis International. 23(3), pp. 811 - 820. https://doi.org/10.1007/s00198-011-1694-y
Fracture risk assessment
McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John A.. (2012). Fracture risk assessment. Clinical Biochemistry. 45(12), pp. 887 - 893. https://doi.org/10.1016/j.clinbiochem.2012.05.001
An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis
Lekamwasam, S., Adachi, Jonathan D., Agnusdei, D., Bilezikian, J P., Boonen, S., Borgström, F., Cooper, Cyrus, Perez, A. Diez, Eastell, Richard, Hofbauer, L. C., Kanis, John A., Langdahl, B. L., Lesnyak, Olga, Lorenc, R. S., McCloskey, Eugene, Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, Stuart H., ... Compston, Juliet E.. (2012). An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis. Archives of Osteoporosis. 7(2017-02-01), pp. 25 - 30. https://doi.org/10.1007/s11657-012-0070-7
Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Austin, Matthew S., Siris, E. S., Wang, Andrea, Lewiecki, E. Michael, Lorenc, R. S., Libanati, Cesar and Kanis, John A.. (2012). Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX. Journal of Bone and Mineral Research. 27(7), pp. 1480 - 1486. https://doi.org/10.1002/jbmr.1606
The distribution of FRAX®-based probabilities in women from Japan
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2012). The distribution of FRAX®-based probabilities in women from Japan. Journal of Bone and Mineral Metabolism. 30(6), pp. 700 - 705. https://doi.org/10.1007/s00774-012-0371-3
A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study
Shepstone, L., Fordham, R., Lenaghan, E., Harvey, I., Cooper, Cyrus, Gittoes, Neil, Heawood, A., Peters, T. J., O¿Neill, T. W., Torgerson, David, Holland, R., Howe, A., Marshall, T., Kanis, John A. and McCloskey, Eugene. (2012). A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study. Osteoporosis International. 23(10), pp. 2507 - 2515. https://doi.org/10.1007/s00198-011-1876-7
Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial
Tieland, Michael, De Rest, Ondine Van, Dirks, Marlou L., Van Der Zwalu, Nikita L., Mensink, Marco, Van Loon, Luc and de Groot, Lisette C. P. G. M.. (2012). Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of the American Medical Directors Association. 13(8), pp. 720 - 726. https://doi.org/10.1016/j.jamda.2012.07.005
Frailty and sarcopenia: Definitions and outcome parameters
Cooper, Cyrus, Dere, W., Evans, William J., Kanis, John A., Rizzoli, R, Sayer, A. A., Sieber, C. C., Kaufman, J, Van Kan, G. Abellan, Boonen, S., Adachi, Jonathan, Mitlak, B., Tsouderos, Y., Rolland, Y. and Reginster, Jean Yves. (2012). Frailty and sarcopenia: Definitions and outcome parameters. Osteoporosis International. 23(7), pp. 1839 - 1848. https://doi.org/10.1007/s00198-012-1913-1
Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures
Lalmohamed, A., Welsing, P. M. J., Lems, Willem F., Jacobs, J. W. G., Kanis, John A., Johansson, Helena, De Boer, A. and De Vries, F.. (2012). Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures. Osteoporosis International. 23(3), pp. 861 - 869. https://doi.org/10.1007/s00198-011-1852-2
Fracture prediction and calibration of a Canadian FRAX® tool: A population-based report from CaMos
Fraser, L.-A., Langsetmo, L., Berger, C., Ioannidis, G., Goltzman, David, Adachi, Jonathan D., Papaioannou, A., Josse, R. G., Kovacs, C. S., Olszynski, W. P., Towheed, T., Hanley, David A., Kaiser, S. M., Prior, J., Jamal, S., Kreiger, N., Brown, J. P., Johansson, Helena, Oden, Anders, ... Leslie, William D.. (2011). Fracture prediction and calibration of a Canadian FRAX® tool: A population-based report from CaMos. Osteoporosis International. 22(3), pp. 829 - 837. https://doi.org/10.1007/s00198-010-1465-1
A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX®
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2011). A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX®. Osteoporosis International. 22(8), pp. 2347 - 2355. https://doi.org/10.1007/s00198-010-1474-0
Evaluation of FRAX to characterise fracture risk in Poland
Czerwinski, E., Kanis, John A., Osieleniec, J., Kumorek, A., Milert, A., Johansson, Helena, McCloskey, Eugene V. and Gorkiewicz, M.. (2011). Evaluation of FRAX to characterise fracture risk in Poland. Osteoporosis International. 22(9), pp. 2507 - 2512. https://doi.org/10.1007/s00198-010-1502-0
Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report
Rizzoli, R, Åkesson, K., Bouxsein, M. L., Kanis, John A., Napoli, N., Papapoulos, S., Reginster, Jean Yves and Cooper, Cyrus. (2011). Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporosis International. 22(2), pp. 373 - 390. https://doi.org/10.1007/s00198-010-1453-5
Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment
Leslie, William D., Lix, Lisa M., Langsetmo, L., Berger, C., Goltzman, David, Hanley, David A., Adachi, J. D., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011). Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment. Osteoporosis International. 22(3), pp. 817 - 827. https://doi.org/10.1007/s00198-010-1464-2
Interpretation and use of FRAX in clinical practice
Kanis, John A., Hans, D., Cooper, Cyrus, Baim, Sanford, Bilezikian, J. P., Binkley, Neil, Cauley, Jane A., Compston, Juliet E., Dawson-Hughes, Bess, Fuleihan, Ghada El-Hajj, Johansson, Helena, Leslie, William D., Lewiecki, E. Michael, Luckey, Marjorie M., Oden, Anders, Papapoulos, S., Poiana, Catalina, Rizzoli, R, Wahl, D. A. and McCloskey, Eugene. (2011). Interpretation and use of FRAX in clinical practice. Osteoporosis International. 22(9), pp. 2395 - 2411. https://doi.org/10.1007/s00198-011-1713-z
FRAX - modell för att beräkna 10-årsrisken för fraktur
Johansson, Helena, Kanis, John, Ljunggren, Östen, Ström, O., Svensson, Olle and Mellström, Dan. (2011). FRAX - modell för att beräkna 10-årsrisken för fraktur. Lakartidningen. 108(7), pp. 336 - 339.
Increasing age- and sex-specific rates of hip fracture in Mexico: A survey of the Mexican institute of social security
Johansson, Helena, Clark, P., Carlos, F., Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011). Increasing age- and sex-specific rates of hip fracture in Mexico: A survey of the Mexican institute of social security. Osteoporosis International. 22(8), pp. 2359 - 2364. https://doi.org/10.1007/s00198-010-1475-z
Epidemiological burden of postmenopausal osteoporosis in the UK from 2010 to 2021: Estimations from a disease model
Gauthier, A., Kanis, John A., Jiang, Yling, Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2011). Epidemiological burden of postmenopausal osteoporosis in the UK from 2010 to 2021: Estimations from a disease model. Archives of Osteoporosis. 6(2017-02-01), pp. 179 - 188. https://doi.org/10.1007/s11657-011-0063-y
Joint official positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. Executive Summary of the 2010 Position Development Conference on Interpretation and Use of FRAX® in Clinical Practice
Hans, Dieder B. L., Kanis, John A., Baim, Sanford, Bilezikian, John P., Binkley, Neil, Cauley, Jane A., Compston, Juliet E., Cooper, Cyrus, Dawson-Hughes, Bess, El-Hajj Fuleihan, Ghada, Leslie, William D., Lewiecki, E. Michael, Luckey, Marjorie M., McCloskey, Eugene V., Papapoulos, Socrates E., Poiana, Catalina and Rizzoli, Rene. (2011). Joint official positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. Executive Summary of the 2010 Position Development Conference on Interpretation and Use of FRAX® in Clinical Practice. Journal of Clinical Densitometry. 14(3), pp. 171 - 180. https://doi.org/10.1016/j.jocd.2011.05.007
Development and validation of a disease model for postmenopausal osteoporosis
Gauthier, A., Kanis, John A., Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2011). Development and validation of a disease model for postmenopausal osteoporosis. Osteoporosis International. 22(3), pp. 771 - 780. https://doi.org/10.1007/s00198-010-1358-3
Partial adherence: A new perspective on health economic assessment in osteoporosis
Kanis, John A., Cooper, Cyrus, Hiligsmann, Mickaël, Rabenda, V., Reginster, Jean-Yves and Rizzoli, R.. (2011). Partial adherence: A new perspective on health economic assessment in osteoporosis. Osteoporosis International. 22(10), pp. 2565 - 2573. https://doi.org/10.1007/s00198-011-1668-0
The application of FRAX® to determine intervention thresholds in osteoporosis treatment in Poland
Badurski, Janusz E., Kanis, John A., Johansson, Helena, Dobrenko, Andrzej, Nowak, Nonna A., Daniluk, Stefan and Jezienicka, Elzbieta. (2011). The application of FRAX® to determine intervention thresholds in osteoporosis treatment in Poland. Polish Archives of Internal Medicine. 121(5), pp. 148 - 155.
Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis
Jönsson, Bengt, Ström, O., Eisman, John A., Papaioannou, A., Siris, E. S., Tosteson, Anna N. A. and Kanis, John A.. (2011). Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis. Osteoporosis International. 22(3), pp. 967 - 982. https://doi.org/10.1007/s00198-010-1424-x
Osteoporosis: Burden, health care provision and opportunities in the EU
Ström, O., Borgström, F., Kanis, John A., Compston, Juliet E., Cooper, Cyrus, McCloskey, Eugene V. and Jönsson, B.. (2011). Osteoporosis: Burden, health care provision and opportunities in the EU. Archives of Osteoporosis. 6(42767), pp. 59 - 155. https://doi.org/10.1007/s11657-011-0060-1
Guidance for the adjustment of FRAX according to the dose of glucocorticoids
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2011). Guidance for the adjustment of FRAX according to the dose of glucocorticoids. Osteoporosis International. 22(3), pp. 809 - 816. https://doi.org/10.1007/s00198-010-1524-7
Exercise-Induced splanchnic hypoperfusion results in gut dysfunction in healthy men
Wijck, Kim V., Lenaerts, Kaatje, Van Loon, Luc, Peters, Wilbert H. M., Buurman, Wim A. and Dejong, Cornelis H. C.. (2011). Exercise-Induced splanchnic hypoperfusion results in gut dysfunction in healthy men. PLoS ONE. 6(7), pp. 1 - 10. https://doi.org/10.1371/journal.pone.0022366
Official positions for FRAX® Bone Mineral Density and FRAX® Simplification. From Joint official positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX
Lewiecki, E. Michael, Compston, Juliet E., Miller, Paul D., Adachi, Jonathan D., Adams, Judith E., Leslie, William D., Kanis, John A., Moayyeri, Alireza, Adler, Robert A., Hans, Didier B., Kendler, David L., Diez-Perez, Adolfo, Krieg, Marc-Antoine, Masri, Basel K., Lorenc, Roman R., Bauer, Douglas C., Blake, Glen M., Josse, Robert G., Clark, Patricia and Khan, Aliya A.. (2011). Official positions for FRAX® Bone Mineral Density and FRAX® Simplification. From Joint official positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX. Journal of Clinical Densitometry. 14(3), pp. 226 - 236. https://doi.org/10.1016/j.jocd.2011.05.017
Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis
Rizzoli, Rene, Reginster, Jean-Yves, Boonen, Steven, Bréart, Gérard, Diez-Perez, Adolfo, Felsenberg, Dieter, Kaufman, Jean-Marc, Kanis, John A. and Cooper, Cyrus. (2011). Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis. Calcified Tissue International. 89(2), pp. 91 - 104. https://doi.org/10.1007/s00223-011-9499-8
Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance
Looker, A. C., Dawson-Hughes, B., Tosteson, Anna N. A., Johansson, Helena, Kanis, John A. and Melton, Lisa J.. (2011). Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance. Osteoporosis International. 22(2), pp. 541 - 549. https://doi.org/10.1007/s00198-010-1288-0
Spine-hip discordance and fracture risk assessment: A physician-friendly FRAX enhancement
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011). Spine-hip discordance and fracture risk assessment: A physician-friendly FRAX enhancement. Osteoporosis International. 22(3), pp. 839 - 847. https://doi.org/10.1007/s00198-010-1461-5
Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden
Johansson, Helena, Oden, Anders, Kanis, John A., McCloskey, Eugene V., Lorentzon, Mattias, Ljunggren, Östen, Karlsson, Magnus K., Orwoll, E., Tivesten, A., Ohlsson, Claes and Mellström, Dan. (2011). Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden. Osteoporosis International. 22(5), pp. 1411 - 1418. https://doi.org/10.1007/s00198-010-1331-1
Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards
Vasikaran, Samuel, Eastell, Richard, Bruyere, O., Foldes, A. J., Garnero, P., Griesmacher, Andrea, McClung, Michael R., Morris, Howard A., Silverman, S., Trenti, Tommaso, Wahl, D. A., Cooper, Cyrus and Kanis, John A.. (2011). Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards. Osteoporosis International. 22(2), pp. 391 - 420. https://doi.org/10.1007/s00198-010-1501-1
Milk intake and risk of hip fracture in men and women: A meta-analysis of prospective cohort studies
Bischoff-Ferrari, Heike A., Dawson-Hughes, Bess, Baron, John A., Kanis, John A., Orav, Endel J., Staehelin, Hannes B., Kiel, Douglas P., Burckhardt, Peter, Henschkowski, Jana, Spiegelman, Donna, Li, Ruifeng, Wong, John B., Feskanich, Diane and Willett, Walter C.. (2011). Milk intake and risk of hip fracture in men and women: A meta-analysis of prospective cohort studies. Journal of Bone and Mineral Research. 26(4), pp. 833 - 839. https://doi.org/10.1002/jbmr.279
Secular trends in the incidence of hip and other osteoporotic fractures
Cooper, Cyrus, Cole, Z. A., Holroyd, C. R., Earl, S. C., Harvey, Nicholas C., Dennison, Elaine M., Melton, Lisa, Cummings, Steven R. and Kanis, John A.. (2011). Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporosis International. 22(5), pp. 1277 - 1288. https://doi.org/10.1007/s00198-011-1601-6
A FRAX® model for the assessment of fracture probability in Belgium
Johansson, Helena, Kanis, John, McCloskey, Eugene, Oden, Anders, Devogelaer, J. P., Kaufman, J-M, Neuprez, A., Hiligsmann, Mickaël, Bruyère, O. and Reginster, Jean Yves. (2011). A FRAX® model for the assessment of fracture probability in Belgium. Osteoporosis International. 22(2), pp. 453 - 461. https://doi.org/10.1007/s00198-010-1218-1
International osteoporosis foundation and international federation of clinical chemistry and laboratory medicine position on bone marker standards in osteoporosis
Vasikaran, Samuel, Cooper, Cyrus, Eastell, Richard, Griesmacher, Andrea, Morris, Howard A., Trenti, Tommaso and Kanis, John A.. (2011). International osteoporosis foundation and international federation of clinical chemistry and laboratory medicine position on bone marker standards in osteoporosis. Clinical Chemistry and Laboratory Medicine. 49(8), pp. 1271 - 1274. https://doi.org/10.1515/CCLM.2011.602
Cost-effectiveness of bazedoxifene incorporating the FRAX® algorithm in a European perspective
Borgström, F., Ström, O., Kleman, M., McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John A.. (2011). Cost-effectiveness of bazedoxifene incorporating the FRAX® algorithm in a European perspective. Osteoporosis International. 22(3), pp. 955 - 965. https://doi.org/10.1007/s00198-010-1291-5
Identifying cost-effective treatment with raloxifene in postmenopausal women using risk algorithms for fractures and invasive breast cancer
Ivergãrd, M., Ström, O., Borgström, F., Burge, R., Tosteson, Anna N. A. and Kanis, John. (2010). Identifying cost-effective treatment with raloxifene in postmenopausal women using risk algorithms for fractures and invasive breast cancer. Bone. 47(5), pp. 966 - 974. https://doi.org/10.1016/j.bone.2010.07.024
The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis
Borgström, F., Ström, O., Coelho, J., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010). The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis. Osteoporosis International. 21(2), pp. 339 - 349. https://doi.org/10.1007/s00198-009-0971-5
Independent clinical validation of a Canadian FRAX tool: Fracture prediction and model calibration
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010). Independent clinical validation of a Canadian FRAX tool: Fracture prediction and model calibration. Journal of Bone and Mineral Research. 25(11), pp. 2350 - 2358. https://doi.org/10.1002/jbmr.123
Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer
McCloskey, Eugene, Paterson, Alexander, Kanis, John, Tähtelä, Rita and Powles, Trevor. (2010). Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer. European Journal of Cancer. 46(3), pp. 558 - 565. https://doi.org/10.1016/j.ejca.2009.12.003
FRAX® and its applications in health economics-Cost-effectiveness and intervention thresholds using bazedoxifene in a Swedish setting as an example
Ström, O., Borgström, F., Kleman, M., McCloskey, Eugene, Oden, Anders, Johansson, Helena and Kanis, John. (2010). FRAX® and its applications in health economics-Cost-effectiveness and intervention thresholds using bazedoxifene in a Swedish setting as an example. Bone. 47(2), pp. 430 - 437. https://doi.org/10.1016/j.bone.2010.05.020
Smoking predicts incident fractures in elderly men: Mr OS Sweden
Jutberger, Hans, Lorentzon, Mattias, Barrett-Connor, Elizabeth, Johansson, Helena, Kanis, John, Ljunggren, Östen, Karlsson, Magnus, Rosengren, Björn E., Redlund-Johnell, Inga, Orwoll, E, Ohlsson, Claes and Mellström, Dan. (2010). Smoking predicts incident fractures in elderly men: Mr OS Sweden. Journal of Bone and Mineral Research. 25(5), pp. 1010 - 1016. https://doi.org/10.1359/jbmr.091112
An evaluation of the NICE guidance for the prevention of osteoporotic fragility fractures in postmenopausal women
Kanis, John, McCloskey, Eugene, Jonsson, Bengt, Cooper, Alun, Ström, O. and Borgström, F.. (2010). An evaluation of the NICE guidance for the prevention of osteoporotic fragility fractures in postmenopausal women. Archives of Osteoporosis. 5(43862), pp. 19 - 48. https://doi.org/10.1007/s11657-010-0045-5
Application of the national osteoporosis foundation guidelines to postmenopausal women and men: The Framingham osteoporosis study
Berry, S. D., Kiel, Douglas P., Donaldson, Meghan G., Cummings, Steven R., Kanis, John, Johansson, Helena and Samelson, E. J.. (2010). Application of the national osteoporosis foundation guidelines to postmenopausal women and men: The Framingham osteoporosis study. Osteoporosis International. 21(1), pp. 53 - 60. https://doi.org/10.1007/s00198-009-1127-3
The need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: A view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Bruyère, O., Kanis, John, Ibar-Abadie, M. E., Alsayed, N., Brandi, Maria Luisa, Burlet, N., Cahall, D., Chines, A., Devogelaer, J. P., Dere, W., Goel, N., Hughes, N., Kaufman, J-M, Korte, S., Mitlak, Bruce, Niese, D., Rizzoli, Rene, Rovati, Lucio C. and Reginster, Jean Yves. (2010). The need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: A view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporosis International. 21(5), pp. 713 - 722. https://doi.org/10.1007/s00198-010-1190-9
Validation of the IOF quality of life questionnaire for patients with wrist fracture
Lips, P., Jameson, Karen A., Bianchi, Maria L., Goemaere, Stefan, Boonen, Steven, Reeve, Jonathan, Stepan, Jan J., Johnell, O., van Schoor, Natasja M., Dennison, Elaine M., Kanis, John and Cooper, Cyrus. (2010). Validation of the IOF quality of life questionnaire for patients with wrist fracture. Osteoporosis International. 21(1), pp. 61 - 70. https://doi.org/10.1007/s00198-009-0946-6
The cost-effectiveness of risedronate in the UK for the management of osteoporosis using the FRAX®
Borgström, F., Ström, O., Coelho, J., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010). The cost-effectiveness of risedronate in the UK for the management of osteoporosis using the FRAX®. Osteoporosis International. 21(3), pp. 495 - 505. https://doi.org/10.1007/s00198-009-0989-8
Nutritional strategies to promote postexercise recovery
Beelen, M, Burke, Louise, Gibala, M and van Loon, Luc. (2010). Nutritional strategies to promote postexercise recovery. International Journal of Sport Nutrition and Exercise Metabolism. 20(6), pp. 515 - 532. https://doi.org/10.1123/ijsnem.20.6.515
The effects of a FRAX® revision for the USA
Kanis, John, Johansson, Helena, Oden, Anders, Dawson-Hughes, Bess, Melton, Lisa and McCloskey, Eugene. (2010). The effects of a FRAX® revision for the USA. Osteoporosis International. 21(1), pp. 35 - 40. https://doi.org/10.1007/s00198-009-1033-8
FRAX assessment of osteoporotic fracture probability in Switzerland
Lippuner, K., Johansson, Helena, Kanis, John and Rizzoli, Rene. (2010). FRAX assessment of osteoporotic fracture probability in Switzerland. Osteoporosis International. 21(3), pp. 381 - 389. https://doi.org/10.1007/s00198-009-0975-1
The potential impact of new National Osteoporosis Foundation guidance on treatment patterns
Dawson-Hughes, Bess, Looker, A. C., Tosteson, Anna N. A., Johansson, Helena, Kanis, John and Melton, Lisa. (2010). The potential impact of new National Osteoporosis Foundation guidance on treatment patterns. Osteoporosis International. 21(1), pp. 41 - 52. https://doi.org/10.1007/s00198-009-1034-7
A meta-analysis of the efficacy of raloxifene on all clinical and vertebral fractures and its dependency on FRAX®
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2010). A meta-analysis of the efficacy of raloxifene on all clinical and vertebral fractures and its dependency on FRAX®. Bone. 47(4), pp. 729 - 735. https://doi.org/10.1016/j.bone.2010.06.009
The incidence and risk of hip fracture in Poland
Czerwinski, E., Kanis, John, Trybulec, B., Johansson, Helena, Borowy, P. and Osieleniec, J.. (2009). The incidence and risk of hip fracture in Poland. Osteoporosis International. 20(8), pp. 1363 - 1367. https://doi.org/10.1007/s00198-008-0787-8
BMD, clinical risk factors and their combination for hip fracture prevention
Johansson, Helena, Kanis, John, Oden, Anders, Johnell, O. and McCloskey, Eugene. (2009). BMD, clinical risk factors and their combination for hip fracture prevention. Osteoporosis International. 20(10), pp. 1675 - 1682. https://doi.org/10.1007/s00198-009-0845-x
How to decide who to treat
Kanis, John, McCloskey, Eugene, Johansson, Helena, Ström, O., Borgström, F. and Oden, Anders. (2009). How to decide who to treat. Best Practice and Research: Clinical Rheumatology. 23(6), pp. 711 - 726. https://doi.org/10.1016/j.berh.2009.09.002
FRAX® and its applications to clinical practice
Kanis, John, Oden, Anders, Johansson, Helena, Borgström, F., Ström, O. and McCloskey, Eugene. (2009). FRAX® and its applications to clinical practice. Bone. 44(5), pp. 734 - 743. https://doi.org/10.1016/j.bone.2009.01.373
Can fall risk be incorporated into fracture risk assessment algorithms: A pilot study of responsiveness to clodronate
Kayan, K., Johansson, Helena, Oden, Anders, Vasireddy, S., Pande, K., Orgee, J., Kanis, John and McCloskey, Eugene. (2009). Can fall risk be incorporated into fracture risk assessment algorithms: A pilot study of responsiveness to clodronate. Osteoporosis International. 20(12), pp. 2055 - 2061. https://doi.org/10.1007/s00198-009-0942-x
Approaches to the targeting of treatment for osteoporosis.
Kanis, John, McCloskey, Eugene, Johansson, Helena and Oden, Anders. (2009). Approaches to the targeting of treatment for osteoporosis. Nature Reviews Rheumatology. 5(8), pp. 425 - 431. https://doi.org/10.1038/nrrheum.2009.139
Cost-effectiveness of hormone therapy in the United States
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2009). Cost-effectiveness of hormone therapy in the United States. Journal of Women's Health. 18(10), pp. 1669 - 1677. https://doi.org/10.1089/jwh.2008.1246
An updated systematic review of health state utility values for osteoporosis related conditions
Peasgood, T., Herrmann, K., Kanis, John and Brazier, J. E.. (2009). An updated systematic review of health state utility values for osteoporosis related conditions. Osteoporosis International. 20(6), pp. 853 - 868. https://doi.org/10.1007/s00198-009-0844-y
Assessment of fracture risk
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2009). Assessment of fracture risk. European Journal of Radiology. 71(3), pp. 392 - 397. https://doi.org/10.1007/s11914-011-0093-9
Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women
Lippuner, K., Johansson, Helena, Kanis, John and Rizzoli, Rene. (2009). Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women. Osteoporosis International. 20(7), pp. 1131 - 1140. https://doi.org/10.1007/s00198-008-0779-8
Ten-year fracture probability identifies women who will benefit from clodronate therapy-additional results from a double-blind, placebo-controlled randomised study
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Vasireddy, S., Kayan, K., Pande, K., Jalava, T. and Kanis, John. (2009). Ten-year fracture probability identifies women who will benefit from clodronate therapy-additional results from a double-blind, placebo-controlled randomised study. Osteoporosis International. 20(5), pp. 811 - 817. https://doi.org/10.1007/s00198-008-0786-9
Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK
Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Francis, Roger M., Kanis, John, Marsh, D., McCloskey, Eugene, Reid, David M., Selby, P. and Wilkins, M.. (2009). Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK. Maturitas. 62(2), pp. 105 - 108. https://doi.org/10.1016/j.maturitas.2008.11.022
Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2009). Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®. Bone. 44(6), pp. 1049 - 1054. https://doi.org/10.1016/j.bone.2009.02.014
From relative risk to absolute fracture risk calculation: The FRAX algorithm
McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John. (2009). From relative risk to absolute fracture risk calculation: The FRAX algorithm. Current Osteoporosis Reports. 7(3), pp. 77 - 83. https://doi.org/10.1007/s11914-009-0013-4
Incorporating adherence into health economic modelling of osteoporosis
Ström, O., Borgström, Frederick, Kanis, John and Jönsson, B.. (2009). Incorporating adherence into health economic modelling of osteoporosis. Osteoporosis International. 20(1), pp. 23 - 34. https://doi.org/10.1007/s00198-008-0644-9
Cost-effectiveness of hormone replacement therapy for menopausal symptoms in the UK
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2009). Cost-effectiveness of hormone replacement therapy for menopausal symptoms in the UK. Menopause International. 15(1), pp. 19 - 25. https://doi.org/10.1258/mi.2009.009004
Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores
Tsang, S. W. Y., Kung, Annie Wai Chee, Kanis, John, Johansson, Helena and Oden, Anders. (2009). Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores. Osteoporosis International. 20(11), pp. 1939 - 1945. https://doi.org/10.1007/s00198-009-0906-1
Assessment of the 10-year probability of osteoporotic hip fracture combining clinical risk factors and heel bone ultrasound: The EPISEM prospective cohort of 12,958 elderly women
Hans, Didier, Durosier, Claire, Kanis, John, Johansson, Helena, Schott-Pethelaz, Anne Marie and Krieg, Marc Antoine. (2008). Assessment of the 10-year probability of osteoporotic hip fracture combining clinical risk factors and heel bone ultrasound: The EPISEM prospective cohort of 12,958 elderly women. Journal of Bone and Mineral Research. 23(7), pp. 1045 - 1051. https://doi.org/10.1359/jbmr.080229
Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX)
Fujiwara, S., Nakamura, T., Orimo, H., Hosoi, T., Gorai, I., Oden, Anders, Johansson, Helena and Kanis, John. (2008). Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX). Osteoporosis International. 19(4), pp. 429 - 435. https://doi.org/10.1007/s00198-007-0544-4
The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden
Zethraeus, N., Ström, O., Borgström, Frederick, Kanis, John and Jönsson, B.. (2008). The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden. Osteoporosis International. 19(6), pp. 819 - 827. https://doi.org/10.1007/s00198-007-0511-0
A reference standard for the description of osteoporosis
Kanis, John, McCloskey, Eugene, Johansson, Helena, Oden, Anders, Melton, Lisa and Khaltaev, Nikolai. (2008). A reference standard for the description of osteoporosis. Bone. 42(3), pp. 467 - 475. https://doi.org/10.1016/j.bone.2007.11.001
Health economics of osteoporosis
Borgström, F. and Kanis, John. (2008). Health economics of osteoporosis. Best Practice and Research: Clinical Endocrinology and Metabolism. 22(5), pp. 885 - 900. https://doi.org/10.1016/j.beem.2008.07.005
Vertebral fracture assessment (VPA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis
McCloskey, Eugene, Vasireddy, S., Threlkeld, Jane, Eastaugh, Joanne, Parry, Ailsa, Bonnet, Nicolas, Beneton, Monique, Kanis, John and Charlesworth, Diane. (2008). Vertebral fracture assessment (VPA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis. Journal of Bone and Mineral Research. 23(10), pp. 1561 - 1568. https://doi.org/10.1359/jbmr.080515
Cost effectiveness of hormone therapy in women at high risks of fracture in Sweden, the US and the UK-Results based on the Women's Health Initiative randomised controlled trial
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2008). Cost effectiveness of hormone therapy in women at high risks of fracture in Sweden, the US and the UK-Results based on the Women's Health Initiative randomised controlled trial. Bone. 42(2), pp. 294 - 306. https://doi.org/10.1016/j.bone.2007.09.059
Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis
Goldhahn, J., Scheele, Wim H., Mitlak, Bruce, Abadie, Eric, Aspenberg, Per, Augat, Peter, Brandi, Maria Luisa, Burlet, N., Chines, A., Delmas, P. D., Dupin-Roger, Isabelle, Ethgen, D., Hanson, Beate, Hartl, Florian, Kanis, John, Kewalramani, Reshma, Laslop, A., Marsh, David, Ormarsdottir, Sif, ... Reginster, Jean Yves. (2008). Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis. Bone. 43(2), pp. 343 - 347. https://doi.org/10.1016/j.bone.2008.04.017
FRAX' and the assessment of fracture probability in men and women from the UK
Kanis, John, Johnell, O., Oden, Anders, Johansson, Helena and McCloskey, Eugene. (2008). FRAX' and the assessment of fracture probability in men and women from the UK. Osteoporosis International. 19(4), pp. 385 - 397. https://doi.org/10.1007/s00198-007-0543-5
Case finding for the management of osteoporosis with FRAX® - Assessment and intervention thresholds for the UK
Kanis, John, McCloskey, Eugene, Johansson, Helena, Ström, O., Borgström, F., Oden, Anders, Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Francis, Roger M., Marsh, D., Reid, David M., Selby, P. and Wilkins, M.. (2008). Case finding for the management of osteoporosis with FRAX® - Assessment and intervention thresholds for the UK. Osteoporosis International. 19(10), pp. 1395 - 1408. https://doi.org/10.1007/s00198-008-0712-1
Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: Results of a double-blind, placebo-controlled randomized study
McCloskey, Eugene, Beneton, Monique, Charlesworth, Diane, Kayan, K., DeTakats, Dominic, Dey, Abhijit, Orgee, J., Ashford, Robert, Forster, Martin, Cliffe, Jennifer, Kersh, Linda, Brazier, J. E., Nichol, Jon, Aropuu, Sakari, Jalava, T. and Kanis, John. (2007). Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: Results of a double-blind, placebo-controlled randomized study. Journal of Bone and Mineral Research. 22(1), pp. 135 - 141. https://doi.org/10.1359/jbmr.061008
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women
Kanis, John, Oden, Anders, Johnell, O., Johansson, Helena, Laet, C. De, Brown, Jacques P., Burckhardt, Peter, Cooper, Cyrus, Christiansen, Claus, Cummings, Steven R., Eisman, John A., Fujiwara, S., Glüer, C. C., Goltzman, David, Hans, Didier, Krieg, Marc Antoine, Lacroix, Andrea Z., McCloskey, Eugene, Mellström, Dan, ... Yoshimura, N.. (2007). The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporosis International. 18(8), pp. 1033 - 1046. https://doi.org/10.1007/s00198-007-0343-y
Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis.
Kanis, John, Stevenson, M., McCloskey, Eugene, Davis, S. and Lloyd-Jones, Myfanwy. (2007). Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis. Health Technology Assessment. 11(7). https://doi.org/10.3310/hta11070
Adherence to treatment of osteoporosis: A need for study
Lekkerkerker, F., Kanis, John, Alsayed, N., Bouvenot, G., Burlet, N., Cahall, D., Chines, A., Delmas, P. D., Dreiser, R. L., Ethgen, D., Hughes, N., Kaufman, J-M, Korte, S., Kreutz, G., Laslop, A., Mitlak, Bruce, Rabenda, V., Rizzoli, Rene, Santora, Arthur C., ... Reginster, Jean Yves. (2007). Adherence to treatment of osteoporosis: A need for study. Osteoporosis International. 18(10), pp. 1311 - 1317. https://doi.org/10.1007/s00198-007-0410-4
The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks
van Staa, T. P., Kanis, John, Geusens, P., Boonen, Annelies, Leufkens, H. G. M. and Cooper, Cyrus. (2007). The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks. Value in Health. 10(5), pp. 348 - 357. https://doi.org/10.1111/j.1524-4733.2007.00188.x
Herbert Andre Fleisch, MD : 22 July 1933-15 May 2007.
Martin, T. John, Christiansen, Claus, Kanis, John and Russell, Graham. (2007). Herbert Andre Fleisch, MD : 22 July 1933-15 May 2007. Osteoporosis International. 18(8), pp. 1019 - 1021. https://doi.org/10.1007/s00198-007-0416-y
Cost-effectiveness of the treatment and prevention of osteoporosis - A review of the literature and a reference model
Zethraeus, N., Borgström, F., Ström, O., Kanis, John and Jönsson, B.. (2007). Cost-effectiveness of the treatment and prevention of osteoporosis - A review of the literature and a reference model. Osteoporosis International. 18(1), pp. 9 - 23. https://doi.org/10.1007/s00198-006-0257-0
Latitude, socioeconomic prosperity, mobile phones and hip fracture risk
Johnell, O., Borgström, F., Jönsson, B. and Kanis, John. (2007). Latitude, socioeconomic prosperity, mobile phones and hip fracture risk. Osteoporosis International. 18(3), pp. 333 - 337. https://doi.org/10.1007/s00198-006-0245-4
Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries - An economic evaluation based on the fracture intervention trial
Ström, O., Borgström, Frederick, Sen, S. S., Boonen, Steven, Haentjens, P., Johnell, O. and Kanis, John. (2007). Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries - An economic evaluation based on the fracture intervention trial. Osteoporosis International. 18(8), pp. 1047 - 1061. https://doi.org/10.1007/s00198-007-0349-5
At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis
Borgström, F., Johnell, O., Kanis, John, Jönsson, B. and Rehnberg, C.. (2006). At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis. Osteoporosis International. 17(10), pp. 1459 - 1471. https://doi.org/10.1007/s00198-006-0107-0
Bone fragility in men - Where are we?
Seeman, Ego, Bianchi, Georges, Khosla, Sundeep, Kanis, John and Orwoll, E. (2006). Bone fragility in men - Where are we? Osteoporosis International. 17(11), pp. 1577 - 1583. https://doi.org/10.1007/s00198-006-0160-8
The cost-effectiveness of risedronate in the treatment of osteoporosis: An international perspective
Borgström, F., Carlsson, Å., Sintonen, H., Boonen, Steven, Haentjens, P., Burge, R., Johnell, O., Jönsson, B. and Kanis, John. (2006). The cost-effectiveness of risedronate in the treatment of osteoporosis: An international perspective. Osteoporosis International. 17(7), pp. 996 - 1007. https://doi.org/10.1007/s00198-006-0094-1
The use of multiple sites for the diagnosis of osteoporosis
Kanis, John, Johnell, O., Oden, Anders, Johansson, Helena, Eisman, John A., Fujiwara, S., Kröger, Heikki, Honkanen, Risto, Melton, Lisa, O'Neill, T. W., Reeve, Jonathan, Silman, A. and Tenenhouse, A.. (2006). The use of multiple sites for the diagnosis of osteoporosis. Osteoporosis International. 17(4), pp. 527 - 534. https://doi.org/10.1007/s00198-005-0014-9
Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]
Powles, Trevor, Paterson, Alexander, McCloskey, Eugene, Schein, Phil, Scheffler, Bobbi, Tidy, Alwynne, Ashley, Sue, Smith, Ian, Ottestad, Lars and Kanis, John. (2006). Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. Breast Cancer Research. 8(2). https://doi.org/10.1186/bcr1384
A simple clinical score for estimating the long-term risk of fracture in post-menopausal women
van Staa, T. P., Geusens, P., Kanis, John, Leufkens, H. G. M., Gehlbach, S. and Cooper, Cyrus. (2006). A simple clinical score for estimating the long-term risk of fracture in post-menopausal women. QJM: An International Journal of Medicine. 99(10), pp. 673 - 682. https://doi.org/10.1093/qjmed/hcl094
An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials
Borgström, F., Jönsson, B., Ström, O. and Kanis, John. (2006). An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials. Osteoporosis International. 17(12), pp. 1781 - 1793. https://doi.org/10.1007/s00198-006-0193-z
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
Johnell, O. and Kanis, John. (2006). An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis International. 17(12), pp. 1726 - 1733. https://doi.org/10.1007/s00198-006-0172-4
Preservation of thoracic spine microarchitecture by alendronate: Comparison of histology and microCT
Hordon, L. D., Itoda, M., Shore, P. A., Shore, R. C., Heald, M., Brown, M., Kanis, John, Rodan, G. A. and Aaron, J. E.. (2006). Preservation of thoracic spine microarchitecture by alendronate: Comparison of histology and microCT. Bone. 38(3), pp. 444 - 449. https://doi.org/10.1016/j.bone.2005.09.020