Triage, treatment and transfer : Evidence-based clinical practice recommendations and models of nursing care for the first 72 hours of admission to hospital for acute stroke

Journal article

Middleton, Sandy, Grimley, Rohan and Alexandrov, Anne. (2015) Triage, treatment and transfer : Evidence-based clinical practice recommendations and models of nursing care for the first 72 hours of admission to hospital for acute stroke. Stroke. 46(2), pp. e18-e25. https://doi.org/10.1161/STROKEAHA.114.006139
AuthorsMiddleton, Sandy, Grimley, Rohan and Alexandrov, Anne
Abstract

[Extract] Stroke is a medical emergency and care provided in the first hours is critical in shaping patients’ long-term recovery and prognosis.1 There is robust evidence demonstrating significant reductions in death and disability with early interventions in acute stroke care, including antiplatelet therapy2 stroke unit (SU) care3 and thrombolysis.4 International clinical guidelines for stroke provide key recommendations to guide clinical practice5–8; however, uptake of evidence-based care is variable and often less than optimal.9–14 For example, among patients with ischemic stroke, rates for treatment with intravenous recombinant tissue-type plasminogen activator (r-tPA) are relatively low in the USA (5%)9 and Australia (7%),10 compared with Canada (12%)11 and some European centers (14%).15

Year2015
JournalStroke
Journal citation46 (2), pp. e18-e25
PublisherLippincott Williams & Wilkins Ltd.
ISSN1524-4628
Digital Object Identifier (DOI)https://doi.org/10.1161/STROKEAHA.114.006139
Scopus EID2-s2.0-84922279089
Open accessPublished as green open access
Research or scholarlyResearch
Page rangee18-e25
Research GroupNursing Research Institute
Author's accepted manuscript
File Access Level
Open
Publisher's version
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All rights reserved
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Controlled
Place of publicationUnited States of America
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Eagle, Samantha, Creel, Amy and Alexandrov, Anne. (2012) The Effect of Facilitated Peer Support Sessions on Burnout and Grief Management among Health Care Providers in Pediatric Intensive Care Units : A Pilot Study. Journal of Palliative Medicine. 15(11), pp. 1178 - 1180. https://doi.org/10.1089/jpm.2012.0231
Utility of Cocaine Drug Screens to Predict Safe Delivery of General Anesthesia for ElectiveSurgical Patients
Baxter, Joshua and Alexandrov, Anne. (2012) Utility of Cocaine Drug Screens to Predict Safe Delivery of General Anesthesia for ElectiveSurgical Patients. American Association of Nurse Anesthetists Journal. 80(4 Suppl), pp. S33 - S36.
Improving quality of life by increasing outings after stroke : Study protocol for the Out-and-About trial
McClusky, Annie, Ada, Louise, Middleton, Sandy, Kelly, Patrick J., Goodall, Stephen, Grimshaw, Jeremy M., Logan, Pip, Longworth, Mark and Karageorge, A.. (2012) Improving quality of life by increasing outings after stroke : Study protocol for the Out-and-About trial. International Journal of Stroke. 8(1), pp. 54-58. https://doi.org/10.1111/j.1747-4949.2012.00966.x
Low-power 2-MHz pulsed-wave transcranial ultrasound reduces ischemic brain damage in rats
Alexandrov, Andrei V., Barlinn, Kristian, Strong, Roger, Alexandrov, Anne W. and Aronowski, Jaroslaw. (2011) Low-power 2-MHz pulsed-wave transcranial ultrasound reduces ischemic brain damage in rats. Translational Stroke Research. 2(3), pp. 376 - 381. https://doi.org/10.1007/s12975-011-0080-6
Safety and outcomes of intravenous thrombolysis in stroke mimics :A 6-year, single-care center study and a pooled analysis of reported series
Tsivgoulis, Georgios, Alexandrov, Andrei, Chang, Jason, Sharma, Vijay, Hoover, Steven, Lao, Annabelle, Liu, Wei, Stamboulis, Elefterios, Alexandrov, Anne, Malkoff, Marc, Frey, James and Frey, James. (2011) Safety and outcomes of intravenous thrombolysis in stroke mimics :A 6-year, single-care center study and a pooled analysis of reported series. Stroke: a journal of cerebral circulation. 42(6), pp. 1771 - 1774. https://doi.org/10.1161/STROKEAHA.110.609339
Reperfusion and outcomes in Penumbra vs. systemic tissue plasminogen activator clinical trials
Alexandrov, Andrei, Schellinger, Peter, Saqqur, Maher, Barreto, Andrew, Demchuk, Andrew, Ribo, Marc, Rubiera, Marta, Sharma, Vijay, Heliopoulos, Ioannis, Alexandrov, Anne, Molina, Carlos, Tsivgoulis, Georgios and Tsivgoulis, Georgios. (2011) Reperfusion and outcomes in Penumbra vs. systemic tissue plasminogen activator clinical trials. International Journal of Stroke. 6(2), pp. 118 - 122. https://doi.org/10.1111/j.1747-4949.2010.00559.x
Computed tomography perfusion prognostic maps do not predict reversible and irreversible neurological dysfunction following reperfusion therapies
Zhao, Limin, Barlinn, Kristian, Bag, Asim, Kesani, Maruthi, Cava, Luis, Balucani, Clotilde, Alexandrov, Anne, Horton, Joseph, Patterson, Damon and Harrigan, Mark. (2011) Computed tomography perfusion prognostic maps do not predict reversible and irreversible neurological dysfunction following reperfusion therapies. International Journal of Stroke. 6(6), pp. 544 - 546. https://doi.org/10.1111/j.1747-4949.2011.00681.x
Safety and tolerability of early noninvasive ventilatory correction using bilevel positive airway pressure in acute ischemic stroke
Tsivgoulis, Georgios, Zhang, Yi, Alexandrov, Anne, Harrigan, Mark, Sisson, April, Zhao, Limin, Brethour, Mary, Cava, Luis, Balucani, Clotilde, Barlinn, Kristian, Patterson, Damon, Giannopoulos, Sotirios, DeWolfe, Jennifer and Alexandrov, Andrei. (2011) Safety and tolerability of early noninvasive ventilatory correction using bilevel positive airway pressure in acute ischemic stroke. Stroke: a journal of cerebral circulation. 42(4), pp. 1030 - 1034. https://doi.org/10.1161/STROKEAHA.110.600221
End-diastolic velocity increase predicts recanalization and neurological improvement in patients with ischemic stroke with proximal arterial occlusions receiving reperfusion therapies
Alexandrov, Andrei, Tsivgoulis, Georgios, Rubiera, Marta, Vadikolias, Konstantinos, Stamboulis, Elefterios, Molina, Carlos and Alexandrov, Anne. (2010) End-diastolic velocity increase predicts recanalization and neurological improvement in patients with ischemic stroke with proximal arterial occlusions receiving reperfusion therapies. Stroke: a journal of cerebral circulation. 41(5), pp. 948 - 952. https://doi.org/10.1161/STROKEAHA.109.577502
What is a stroke?
Alexandrov, Anne W.. (2010) What is a stroke? In In J. Williams, L. Perry and C. Watkins (Ed.). Acute Stroke Nursing pp. 33 - 65
Acute stroke nursing management
Alexandrov, Anne W.. (2010) Acute stroke nursing management. In In J. Williams, L. Perry and C. Watkins (Ed.). Acute Stroke Nursing pp. 66 - 90 Blackwell Publishing.
Postgraduate fellowship education and training for nurses: The NET SMART Experience
Alexandrov, Anne W., Brethour, Mary K., Cudlip, Fern, Swatzell, Victoria, Biby, Sharon, Reiner, Dana, Kiernan, Terri-Ellen, Handler, Diane, Tocco, Susan and Yang, Joanna Jiehong. (2009) Postgraduate fellowship education and training for nurses: The NET SMART Experience. Critical Care Nursing Clinics of North America. 21(4), pp. 435 - 449. https://doi.org/10.1016/j.ccell.2009.09.001
Pre-tissue plasminogen activator blood pressure levels and risk of symptomatic intracerebral hemorrhage
Tsivgoulis, Georgios, Frey, James L., Flaster, Murray, Sharma, Vijay K., Lao, Annabelle Y., Hoover, Steven L., Liu, Wei, Stamboulis, Elefterios, Alexandrov, Anne W., Malkoff, Marc D. and Alexandrov, Andrei V.. (2009) Pre-tissue plasminogen activator blood pressure levels and risk of symptomatic intracerebral hemorrhage. Stroke: a journal of cerebral circulation. 40(11), pp. 3631 - 3634. https://doi.org/10.1161/STROKEAHA.109.564096
Prevalence and risk factors associated with reversed robin hood syndrome in acute ischemic stroke
Alexandrov, Andrei V., Nguyen, Huy Thang, Rubiera, Marta, Alexandrov, Anne W., Zhao, Limin, Heliopoulos, Ioannis, Robinson, Alice, DeWolfe, Jennifer and Tsivgoulis, Georgios. (2009) Prevalence and risk factors associated with reversed robin hood syndrome in acute ischemic stroke. Stroke: a journal of cerebral circulation. 40(8), pp. 2738 - 2742. https://doi.org/10.1161/STROKEAHA.109.547950
Methodologic challenges in the design and conduct of hyperacute stroke research
Alexandrov, Anne. (2008) Methodologic challenges in the design and conduct of hyperacute stroke research. AACN Advanced Critical Care. 19(2), pp. 186 - 201. https://doi.org/10.1097/01.AACN.0000318122.56759.55
Perfusion augmentation in acute stroke using mechanical counter-pulsation-phase iia: Effect of external counterpulsation on middle cerebral artery mean flow velocity in five healthy subjects
Alexandrov, Anne W., Ribo, Marc, Wong, Kay Sing, Sugg, Rebecca M., Garami, Zsolt, Jesurum, Jill T., Montgomery, Baxter and Alexandrov, Andrei V.. (2008) Perfusion augmentation in acute stroke using mechanical counter-pulsation-phase iia: Effect of external counterpulsation on middle cerebral artery mean flow velocity in five healthy subjects. Stroke: a journal of cerebral circulation. 39(10), pp. 2760 - 2764. https://doi.org/10.1161/STROKEAHA.107.512418
Preliminary findings of external counterpulsation for ischemic stroke patient with large artery occlusive disease
Han, Jing Hao, Leung, Thomas W., Lam, Wynnie W., Soo, Yannie O., Alexandrov, Anne W., Mok, Vincent, Leung, Yee-Fong V., Lo, Raymond and Wong, Ka Sing. (2008) Preliminary findings of external counterpulsation for ischemic stroke patient with large artery occlusive disease. Stroke: a journal of cerebral circulation. 39(4), pp. 1340 - 1343. https://doi.org/10.1161/STROKEAHA.107.500132
Quantification of microspheres appearance in brain vessels: Implications for residual flow velocity measurements, dose calculations, and potential drug delivery
Sharma, Vijay K., Tsivgoulis, Georgios, Lao, Annabelle Y., Malkoff, Marc D., Alexandrov, Anne W. and Alexandrov, Andrei V.. (2008) Quantification of microspheres appearance in brain vessels: Implications for residual flow velocity measurements, dose calculations, and potential drug delivery. Stroke: a journal of cerebral circulation. 39(5), pp. 1476 - 1481. https://doi.org/10.1161/STROKEAHA.107.501593