Comparison of percentage of syllables stuttered with parent-reported severity ratings as a primary outcome measure in clinical trials of early stuttering treatment

Journal article


Onslow, Mark, Jones, Mark, O'Brian, Sue, Packman, Ann, Menzies, Ross, Lowe, Robyn, Arnott, Simone, Bridgman, Kate, Sonneville, Caroline de and Franken, Marie-Christine. (2018). Comparison of percentage of syllables stuttered with parent-reported severity ratings as a primary outcome measure in clinical trials of early stuttering treatment. Journal of Speech, Language, and Hearing Research. 61(4), pp. 811 - 819. https://doi.org/10.1044/2017_JSLHR-S-16-0448
AuthorsOnslow, Mark, Jones, Mark, O'Brian, Sue, Packman, Ann, Menzies, Ross, Lowe, Robyn, Arnott, Simone, Bridgman, Kate, Sonneville, Caroline de and Franken, Marie-Christine
Abstract

Purpose This report investigates whether parent-reported stuttering severity ratings (SRs) provide similar estimates of effect size as percentage of syllables stuttered (%SS) for randomized trials of early stuttering treatment with preschool children. Method Data sets from 3 randomized controlled trials of an early stuttering intervention were selected for analyses. Analyses included median changes and 95% confidence intervals per treatment group, Bland–Altman plots, analysis of covariance, and Spearman rho correlations. Results Both SRs and %SS showed large effect sizes from pretreatment to follow-up, although correlations between the 2 measures were moderate at best. Absolute agreement between the 2 measures improved as percentage reduction of stuttering frequency and severity increased, probably due to innate measurement limitations for participants with low baseline severity. Analysis of covariance for the 3 trials showed consistent results. Conclusion There is no statistical reason to favor %SS over parent-reported stuttering SRs as primary outcomes for clinical trials of early stuttering treatment. However, there are logistical reasons to favor parent-reported stuttering SRs. We conclude that parent-reported rating of the child's typical stuttering severity for the week or month prior to each assessment is a justifiable alternative to %SS as a primary outcome measure in clinical trials of early stuttering treatment.

Year2018
JournalJournal of Speech, Language, and Hearing Research
Journal citation61 (4), pp. 811 - 819
PublisherAmerican Speech - Language - Hearing Association
ISSN1092-4388
Digital Object Identifier (DOI)https://doi.org/10.1044/2017_JSLHR-S-16-0448
Scopus EID2-s2.0-85045525462
Page range811 - 819
Research GroupSchool of Allied Health
Publisher's version
File Access Level
Controlled
Place of publicationUnited States of America
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