Effect of randomization of nasal high flow rate in preterm infants

Journal article


Hough, Judith Leigh, Shearman, Andrew D., Jardine, Luke, Caldararo, Deborah and Schibler, Andreas. (2019). Effect of randomization of nasal high flow rate in preterm infants. Pediatric Pulmonology. 54(9), pp. 1410 - 1416. https://doi.org/10.1002/ppul.24418
AuthorsHough, Judith Leigh, Shearman, Andrew D., Jardine, Luke, Caldararo, Deborah and Schibler, Andreas
Abstract

Objective
To assess the effect of nasal high flow (NHF) cannula on end‐expiratory level (EEL), continuous distending pressure (CDP) and regional ventilation distribution in preterm infants.
Design
A prospective observational clinical study with randomly applied NHF rates.
Patients and Setting
Preterm infants requiring continuous positive airway pressure (CPAP) respiratory support in a Neonatal Intensive Care Unit.
Interventions
Infants were measured on randomly applied flow rates at 2, 4, and 6 L/min of NHF and compared with bubble CPAP.
Measurements and Results
Regional ventilation distribution and EEL were measured using electrical impedance tomography (EIT) and respiratory inductance plethysmography (RIP) in 24 preterm infants (31.19 ± 1.17 weeks corrected age). Changes in CDP were measured from the esophagus via the nasogastric tube. Physiological variables were also recorded. There were no differences in ventilation distribution, EEL or CDP between CPAP and NHF (P > .05). However, the physiological variables of FiO2 (P = .01) and SpO2/FiO2 (P < .01) were improved on CPAP compared with NHF.
Conclusion
NHF applied in random order with flow rates between 2 to 6 L/min was equally as good as CPAP in maintaining EEL and ventilation distribution in stable preterm infants. Overall oxygenation was better on CPAP compared to NHF.

KeywordsNeonatal Pulmonary Medicine; Respiratory Technology; Oxygenation and Therapy; CPAP; electrical impedance tomography; high flow nasal cannula; respiratory inductance plethysmography; ventilation distribution
Year2019
JournalPediatric Pulmonology
Journal citation54 (9), pp. 1410 - 1416
PublisherWiley Periodicals, Inc
ISSN8755-6863
Digital Object Identifier (DOI)https://doi.org/10.1002/ppul.24418
Scopus EID2-s2.0-85071028058
Open accessPublished as green open access
Page range1410 - 1416
Research GroupSchool of Allied Health
Author's accepted manuscript
License
All rights reserved
File Access Level
Open
Publisher's version
License
All rights reserved
File Access Level
Controlled
Place of publicationUnited States of America
EditorsT. Murphy
Permalink -

https://acuresearchbank.acu.edu.au/item/8650v/effect-of-randomization-of-nasal-high-flow-rate-in-preterm-infants

Download files


Author's accepted manuscript
AM_Hough_2019_Effect_of_randomization_of_nasal_high.pdf
License: All rights reserved
File access level: Open

Restricted files

Publisher's version

  • 109
    total views
  • 92
    total downloads
  • 0
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

High flow nasal cannula for respiratory support in term infants (Review)
Dopper, Alex, Steele, Michael, Bogossian, Fiona and Hough, Judith. (2023). High flow nasal cannula for respiratory support in term infants (Review). Cochrane Database of Systematic Reviews. 2023(8), p. Article CD011010. https://doi.org/10.1002/14651858.CD011010.pub2
Physiotherapy practices when treating patients with COVID-19 during a pandemic : A survey study
Trojman, Anthony, Hough, Judith, Hides, Julie, Gustafsson, Louise, Flores, Orlando and Paratz, Jennifer. (2023). Physiotherapy practices when treating patients with COVID-19 during a pandemic : A survey study. Heart and Lung. 57, pp. 152-160. https://doi.org/10.1016/j.hrtlng.2022.09.012
Measuring the effects of airway clearance in mechanically ventilated infants and children : A systematic review
McAlinden, Bronagh M., Hough, Judith L. and Kuys, Suzanne. (2022). Measuring the effects of airway clearance in mechanically ventilated infants and children : A systematic review. Physiotherapy. 117, pp. 47-62. https://doi.org/10.1016/j.physio.2022.08.010
Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates
Blazek, E. V., East, C. E., Jauncey-Cooke, J., Bogossian, F., Grant, C. A. and Hough, J.. (2021). Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates. Cochrane Database of Systematic Reviews. 3, pp. 1-42. https://doi.org/10.1002/14651858.CD009969.pub2.
A quality appraisal using the AGREE II instrument of endotracheal tube suction guidelines in neonatal intensive care units
Hough, Judith L., Barton, Jaimi and Jardine, Luke A.. (2021). A quality appraisal using the AGREE II instrument of endotracheal tube suction guidelines in neonatal intensive care units. Australian Critical Care. 34(6), pp. 524-529. https://doi.org/10.1016/j.aucc.2021.02.001
Chest physiotherapy improves regional lung volume in ventilated children.
McAlinden, B., Kuys, Suzanne Shanelle, Schibler, Andreas and Hough, Judith Leigh. (2020). Chest physiotherapy improves regional lung volume in ventilated children. Critical Care (UK). 24, pp. 1-4. https://doi.org/10.1186/s13054-020-03156-2
Nasal high flow in preterm infants : A dose-finding study
Hough, Judith L., Shearman, Andrew D., Jardine, Luke and Schibler, Andreas. (2019). Nasal high flow in preterm infants : A dose-finding study. Pediatric Pulmonology. 55(3), pp. 616-623. https://doi.org/10.1002/ppul.24617
Simulation-based education improves student self-efficacy in physiotherapy assessment and management of paediatric patients
Hough, Judith, Levan, Daniel Anthony, Steele, Michael, Kelly, Kristine and Dalton, Megan. (2019). Simulation-based education improves student self-efficacy in physiotherapy assessment and management of paediatric patients. BMC Medical Education. 19(1), pp. 1 - 11. https://doi.org/10.1186/s12909-019-1894-2
Chest wall mesenchymal hamartoma in an infant: Evaluation with electrical impedance tomography
Jardine, Luke, Chen, Julie and Hough, Judith Leigh. (2019). Chest wall mesenchymal hamartoma in an infant: Evaluation with electrical impedance tomography. Pediatric Pulmonology. 54(11), pp. E14 - E16. https://doi.org/10.1002/ppul.24483
An evidence-based approach to influencing evidence-based practice in allied health
Wilkinson, Shelley, Hough, Judith Leigh and Hinchliffe, Fiona. (2016). An evidence-based approach to influencing evidence-based practice in allied health. Journal of Allied Health. 45(1), pp. 41-48.
Effect of time and body position on ventilation in premature infants
Hough, Judith Leigh, Trojman, Anthony Paul and Schibler, Andreas. (2016). Effect of time and body position on ventilation in premature infants. Pediatric Research. 80(4), pp. 499 - 504. https://doi.org/10.1038/pr.2016.116
Prevalence and impact of pelvic floor dysfunction in an adult cystic fibrosis population
Chambers, Rebecca, Lucht, Adam John, Reihill, Aisling and Hough, Judith Leigh. (2016). Prevalence and impact of pelvic floor dysfunction in an adult cystic fibrosis population. International Urogynecology Journal and Pelvic Floor Dysfunction. 28(4), pp. 591 - 604. https://doi.org/10.1007/s00192-016-3152-z
Strategies for the withdrawal of humidified high flow nasal cannulae (HHFNC) in preterm infants
Farley, Raymond C., Hough, Judith L. and Jardine, Luke A.. (2015). Strategies for the withdrawal of humidified high flow nasal cannulae (HHFNC) in preterm infants. Cochrane Database of Systematic Reviews. 6, p. Article CD011079. https://doi.org/10.1002/14651858.CD011079.pub2
Lung recruitment and endotracheal suction in ventilated preterm infants measured with electrical impedance tomography
Hough, Judith Leigh, Shearman, Andrew, Liley, Helen, Grant, Caroline and Schibler, Andreas. (2014). Lung recruitment and endotracheal suction in ventilated preterm infants measured with electrical impedance tomography. Journal of Paediatrics and Child Health. 50(11), pp. 884 - 889. https://doi.org/10.1111/jpc.12661
High-flow nasal cannula therapy for respiratory support in children
Mayfield, Sara, Jauncey-Cooke, Jacqueline, Hough, Judith, Schibler, Andreas, Gibbons, Kristen and Bogossian, Fiona Elizabeth. (2014). High-flow nasal cannula therapy for respiratory support in children. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD009850.pub2
Physiologic effect of high-flow nasal cannula in infants with bronchiolitis
Hough, Judith Leigh, Pham, Trang and Schibler, Andreas. (2014). Physiologic effect of high-flow nasal cannula in infants with bronchiolitis. Pediatric Critical Care Medicine. 15(5), pp. e214 - e219. https://doi.org/10.1097/PCC.0000000000000112
The effectiveness of quarter turn from prone in maintaining respiratory function in premature infants
Montgomery, Karly, Low Choy, Nancy, Steele, Michael and Hough, Judith. (2014). The effectiveness of quarter turn from prone in maintaining respiratory function in premature infants. Journal of Paediatrics and Child Health. 50(12), pp. 972 - 977. https://doi.org/10.1111/jpc.12689
Effect of body position on ventilation distribution in ventilated preterm infants
Hough, Judith, Johnston, Leanne, Brauer, Sandy, Woodgate, Paul and Schibler, Andreas. (2013). Effect of body position on ventilation distribution in ventilated preterm infants. Pediatric Critical Care Medicine. https://doi.org/10.1097/PCC.0b013e31826e708a
Effect of body position on ventilation distribution in ventilated preterm infants
Hough, Judith L., Johnston, Leanne, Brauer, Sandy, Woodgate, Paul and Schibler, Andreas. (2013). Effect of body position on ventilation distribution in ventilated preterm infants. Pediatric Critical Care Medicine. 14(2), pp. 171 - 177. https://doi.org/10.1097/PCC.0b013e31826e708a
Baseline evidence based practice use, knowledge, and attitudes of allied health professionals : A survey to inform staff training and organisational change
Wilkinson, Shelley, Hinchliffe, Fiona, Hough, Judith and Chang, Anne. (2012). Baseline evidence based practice use, knowledge, and attitudes of allied health professionals : A survey to inform staff training and organisational change. Journal of Allied Health. 41(4), pp. 177 - 184.
Effect of body position on ventilation distribution in preterm infants on continuous positive airway pressure
Hough, Judith L., Johnston, Leanne, Brauer, Sandy G., Woodgate, Paul G., Pham, Trang MT and Schibler, Andreas. (2012). Effect of body position on ventilation distribution in preterm infants on continuous positive airway pressure. Pediatric Critcal Care Medicine. 13(4), pp. 446 - 451. https://doi.org/10.1097/PCC.0b013e31822f18d9
Talipes equinovarus (clubfoot)
Hough, Judith Leigh, Bagley, Catherine and Koorts, Pieter J.. (2012). Talipes equinovarus (clubfoot). In In M. W. Davies, G. D. T. Inglis and L. A. Jardine & P. J. Koorts (Ed.). Antenatal consults : A guide for neonatologists and paediatricians pp. 281-284 Churchill Livingstone.
Lung recruitment manoeuvres for reducing respiratory morbidity in mechanically ventilated neonates
Jauncey-Cooke, J, Bogossian, F, Hough, J., Schibler, A, Davies, M W., Grant, C A., Gibbons, K and East, C E.. (2012). Lung recruitment manoeuvres for reducing respiratory morbidity in mechanically ventilated neonates. Cochrane Database of Systematic Reviews. Art.No.: CD009969 (Issue 7). https://doi.org/10.1002/14651858.CD009969
Humidified high flow nasal cannulae : Current practice in Australasian nurseries, a survey
Hough, Judith, Shearman, Andrew, Jardine, Luke and Davies, Mark. (2012). Humidified high flow nasal cannulae : Current practice in Australasian nurseries, a survey. Journal of Paediatrics and Child Health. 48(2), pp. 106 - 113. https://doi.org/10.1111/j.1440-1754.2011.02070.x
Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery
Schibler, Andreas, Pham, Trang, Dunster, Kimble, Foster, Kim, Barlow, A, Gibbons, Kristen and Hough, Judith. (2011). Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery. Intensive Care Medicine. 37(5), pp. 847 - 852. https://doi.org/10.1007/s00134-011-2177-5
Measurement of ventilation and cardiac related impedance changes with electrical impedance tomography
Grant, Caroline, Pham, Trang, Hough, Judith, Riedel, T, Stocker, C and Schibler, Andreas. (2011). Measurement of ventilation and cardiac related impedance changes with electrical impedance tomography. Critical Care. 15(1), pp. 1 - 9. https://doi.org/10.1186/cc9985