Lack of prognostic value of type D personality for mortality in a large sample of heart failure patients
Journal article
Coyne, James, Jaarsma, Tiny, Luttik, Marie-Louise, van Sonderen, Eric, van Veldhuisen, Dirk and Sanderman, Robbert. (2011). Lack of prognostic value of type D personality for mortality in a large sample of heart failure patients. Psychosomatic Medicine. 73(7), pp. 557 - 562. https://doi.org/10.1097/PSY.0b013e318227ac75
Authors | Coyne, James, Jaarsma, Tiny, Luttik, Marie-Louise, van Sonderen, Eric, van Veldhuisen, Dirk and Sanderman, Robbert |
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Abstract | Background: Type D personality has been proposed as a prognostic indicator for mortality in cardiovascular disease. Most research examining this construct originates from one research group, and it is critical that the predictive value of Type D personality for adverse outcomes is independently cross-validated. This study examined its prognostic value in heart failure, relative to B-type natriuretic peptide (BNP) and depressive symptoms. Methods: We studied 706 patients with complete BNP, depressive symptom, and Type D personality and mortality data from 958 patients with heart failure enrolled after hospitalization for a multisite study of a disease management program. Multivariable models were adjusted for BNP and depression. Results: At 18 months, there were 192 deaths (27.2%). No evidence was found for a prognostic value of Type D personality in the unadjusted model (hazard ratio [HR] = 0.893, 95% confidence interval [CI] = 0.582-1.370). In contrast, BNP was significantly predictive of mortality (HR = 1.588, 95% CI = 1.391-1.812), whereas depression was not (HR = 1.011, 95% CI = 0.998-1.024). Type D was also not predictive in covariate-adjusted models (HR = 0.779, 95% CI = 0.489-1.242). Similar results were obtained when analyzing Type D as the interaction between continuous z scores of its two components, negative affectivity and social inhibition (p =.144). Conclusions: In the largest study to date, Type D does not predict mortality. Future research should construe Type D as the interaction of continuous negative affectivity and social inhibition z scores, rather than as a typology, and consider analyses replacing negative affectivity with depression. |
Year | 2011 |
Journal | Psychosomatic Medicine |
Journal citation | 73 (7), pp. 557 - 562 |
ISSN | 0033-3174 |
Digital Object Identifier (DOI) | https://doi.org/10.1097/PSY.0b013e318227ac75 |
Page range | 557 - 562 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
https://acuresearchbank.acu.edu.au/item/8671x/lack-of-prognostic-value-of-type-d-personality-for-mortality-in-a-large-sample-of-heart-failure-patients
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