Patient-reported outcomes following parotid-sparing intensity-modulated radiotherapy for head and neck cancer. How important is dysphagia?
Roe, Justin W. G., Drinnan, Michael J., Carding, Paul N., Harrington, Kevin J. and Nutting, Christopher M.. (2014) Patient-reported outcomes following parotid-sparing intensity-modulated radiotherapy for head and neck cancer. How important is dysphagia? Oral Oncology. 50(12), pp. 1182 - 1187. https://doi.org/10.1016/j.oraloncology.2014.09.009
|Authors||Roe, Justin W. G., Drinnan, Michael J., Carding, Paul N., Harrington, Kevin J. and Nutting, Christopher M.|
Objectives: Swallowing can be significantly affected during and following radiotherapy for head and neck cancer (HNC). The purpose of this study was to understand: (1) the trajectory of swallowing recovery following parotid-sparing intensity-modulated radiotherapy (IMRT) and (2) overall physical and social-emotional wellbeing and how patients prioritise swallowing following treatment. Materials and methods: Sixty-one HNC patients completed questionnaires as part of a prospective study exploring patient-reported swallowing outcomes following parotid-sparing IMRT. Participants were asked to complete the M.D. Anderson Dysphagia Inventory (MDADI) and University of Washington Quality of Life Questionnaire (UW-QoL) v.04 before treatment and 3, 6 and 12 months after treatment. Given the rise in human papilloma virus (HPV) and associated oropharyngeal cancers, we completed a sub analysis of the data in those participants. Results: There was a significant reduction in the MDADI composite scores 3 months after completion of treatment. Improvements were observed by 12 months, however, scores did not recover to baseline. The recovery in physical function was limited in comparison to social-emotional recovery at 12 months. When oropharyngeal cancer scores were analysed, there was not a substantial difference to the whole group results. There was a shift in priorities following treatment. Swallowing was highlighted as a concern by 44% of HNC patients up to 12 months after treatment with swallowing-related factors (saliva, taste and chewing) rated highly. Conclusions: Patient reported swallowing outcomes were significantly affected from baseline to all follow-up time points and remained a priority concern at 12 months following treatment. Overall social-emotional functioning does improve, suggesting that patients have the potential to adapt to their “new normal” following IMRT for HNC.
|Keywords||head and neck cancer; oropharyngeal cancer; swallowing; intensity-modulated radiotherapy; quality of life; survivorship|
|Journal citation||50 (12), pp. 1182 - 1187|
|Digital Object Identifier (DOI)||https://doi.org/10.1016/j.oraloncology.2014.09.009|
|Page range||1182 - 1187|
|Place of publication||United Kingdom|
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