FRAX update
Journal article
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, Leslie, William D. and McCloskey, Eugene V.. (2017). FRAX update. Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health. 20(3), pp. 360 - 367. https://doi.org/10.1016/j.jocd.2017.06.022
Authors | Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, Leslie, William D. and McCloskey, Eugene V. |
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Abstract | The fracture risk assessment tool, FRAX, was released in 2008 and provides country-specific algorithms for estimating individualized 10-year probability of hip and major osteoporotic fracture (hip, clinical spine, distal forearm, and proximal humerus). Since its release, models are now available for 63 countries, covering 79% of the world population. The website receives approximately 3 million visits annually. Following independent validation, FRAX has been incorporated into more than 80 guidelines worldwide. However, the application of FRAX in guidelines has been heterogeneous with the adoption of several different approaches to setting intervention thresholds. The relationship between FRAX and efficacy of intervention has been explored and is expected to influence treatment guidelines in the future. A more unified approach to setting intervention thresholds with FRAX is a research priority. |
Keywords | clinical risk factors; fracture probability; FRAX; intervention thresholds; risk assessment |
Year | 2017 |
Journal | Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health |
Journal citation | 20 (3), pp. 360 - 367 |
Publisher | Elsevier |
ISSN | 1094-6950 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.jocd.2017.06.022 |
Scopus EID | 2-s2.0-85024397207 |
Page range | 360 - 367 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
Place of publication | United States of America |
https://acuresearchbank.acu.edu.au/item/868q6/frax-update
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