Personalized medicine and hospitalization for heart failure: If we understand it, we may be successful in treating it
Journal article
Ahmad, Faheem A., Petrie, Mark C., McMurray, John J. V. and Lang, Ninian N.. (2019). Personalized medicine and hospitalization for heart failure: If we understand it, we may be successful in treating it. European Journal of Heart Failure. 21(6), pp. 699 - 702. https://doi.org/10.1002/ejhf.1463
Authors | Ahmad, Faheem A., Petrie, Mark C., McMurray, John J. V. and Lang, Ninian N. |
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Abstract | Randomized trials in patients with hospitalized heart failure (HHF) continue to frustrate the cardiology community. Promising haemodynamic, structural and biomarker findings from phase 2 studies consistently fail to deliver substantive benefits in larger outcome trials. What underlies these recurrent failures? Why are persistently high readmission and post‐discharge mortality rates not being reduced? Challenging any pre‐conceived ideas about the existence of a ‘typical’ acutely decompensated heart failure patient is fundamental, as is the adoption of a carefully personalized approach. These individuals come from a remarkably heterogeneous group. Surely precise phenotyping should translate to a more successful therapeutic approach? |
Year | 2019 |
Journal | European Journal of Heart Failure |
Journal citation | 21 (6), pp. 699 - 702 |
Publisher | John Wiley & Sons |
ISSN | 1388-9842 |
Digital Object Identifier (DOI) | https://doi.org/10.1002/ejhf.1463 |
Scopus EID | 2-s2.0-85064538087 |
Open access | Open access |
Page range | 699 - 702 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | License |
Place of publication | United Kingdom |
https://acuresearchbank.acu.edu.au/item/86q37/personalized-medicine-and-hospitalization-for-heart-failure-if-we-understand-it-we-may-be-successful-in-treating-it
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OA_Ahmad_2019_Personalized_medicine_and_hospitalization_for_heart.pdf | |
License: CC BY 4.0 |
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