A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes
Journal article
Gong, D., Lu, J., Chen, X., Reddy, S., Crossman, D. J., Glyn-Jones, S., Choong, Y.-S., Kennedy, J., Barry, B., Zhang, S., Chan, Y.-K., Ruggiero, K., Phillips, A. R. J. and Cooper, G. J. S.. (2008). A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes. Diabetologia. 51(9), pp. 1741-1751. https://doi.org/10.1007/s00125-008-1088-7
Authors | Gong, D., Lu, J., Chen, X., Reddy, S., Crossman, D. J., Glyn-Jones, S., Choong, Y.-S., Kennedy, J., Barry, B., Zhang, S., Chan, Y.-K., Ruggiero, K., Phillips, A. R. J. and Cooper, G. J. S. |
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Abstract | Aims/hypothesis Methods Results Conclusions/interpretation |
Keywords | albuminuria; diabetic nephropathy; divalent copper; extracellular matrix; glomerular hypertrophy; semicarbazide-sensitive amine oxidase; SSAO; TGF-β; triethylenetetramine |
Year | 2008 |
Journal | Diabetologia |
Journal citation | 51 (9), pp. 1741-1751 |
Publisher | Springer |
ISSN | 0012-186X |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s00125-008-1088-7 |
PubMed ID | 18636238 |
Scopus EID | 2-s2.0-49249098236 |
Page range | 1741-1751 |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 18 Jul 2008 |
Publication process dates | |
Accepted | 21 May 2008 |
https://acuresearchbank.acu.edu.au/item/8706w/a-copper-ii-selective-chelator-ameliorates-diabetes-evoked-renal-fibrosis-and-albuminuria-and-suppresses-pathogenic-tgf-activation-in-the-kidneys-of-rats-used-as-a-model-of-diabetes
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