Bones material constituents and their contribution to bone strength in health, disease, and treatment
Journal article
Bala, Y. and Seeman, Ego. (2015). Bones material constituents and their contribution to bone strength in health, disease, and treatment. Calcified Tissue International. 97(3), pp. 308 - 326. https://doi.org/10.1007/s00223-015-9971-y
Authors | Bala, Y. and Seeman, Ego |
---|---|
Abstract | Type 1 collagen matrix volume, its degree of completeness of its mineralization, the extent of collagen crosslinking and water content, and the non-collagenous proteins like osteopontin and osteocalcin comprise the main constituents of bone’s material composition. Each influences material strength and change in different ways during advancing age, health, disease, and drug therapy. These traits are not quantifiable using bone densitometry and their plurality is better captured by the term bone ‘qualities’ than ‘quality’. These qualities are the subject of this manuscript. |
Keywords | bone water; collagen; mineralization; osteopontin; osteocalcin; pentosidine; qualities of bone |
Year | 2015 |
Journal | Calcified Tissue International |
Journal citation | 97 (3), pp. 308 - 326 |
Publisher | Springer New York LLC |
ISSN | 0171-967X |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s00223-015-9971-y |
Page range | 308 - 326 |
Research Group | Institute for Health and Ageing |
Publisher's version | File Access Level Controlled |
Place of publication | Germany |
Permalink -
https://acuresearchbank.acu.edu.au/item/8718z/bones-material-constituents-and-their-contribution-to-bone-strength-in-health-disease-and-treatment
Restricted files
Publisher's version
(1 files)
111
total views0
total downloads0
views this month0
downloads this month