A randomized clinical trial to evaluate the effect of diet on weight loss and coping of people living with HIV and lipodystrophy

Aim. The purpose of the research study was to evaluate a diet intervention in relation to the perceived weight loss and ways of coping of people living with HIV and lipodystrophy. The objectives were (i) to measure the perceived impact of weight loss upon men with HIV and lipodystrophy following a diet intervention and (ii) to identify strategies used by men to cope with HIV and lipodystrophy following a diet intervention.

Background. HIV positive people on antiretroviral treatments are normalizing their lives and are facing a life-long future. Morphological changes occur as a result of antiretroviral therapy causing HIV positive people to hesitate commencing treatment.

Design. An experimental design incorporating pretests and posttests of experimental and control groups was used in the study.

Methods. The sample consisted of 30 men over 18 years of age, living with HIV and lipodystrophy. All participants were surveyed by questionnaires and their perceived weight loss and ways of coping were measured at baseline and 10 weeks.

Results. Findings indicated a significant improvement for perceived weight loss and although not significant, all coping processes were used more by the participants in the intervention group compared with the control group.

Conclusions. The diet intervention demonstrated a positive effect particularly upon perceived weight loss on men living with HIV and Lipodystrophy in the study setting.

Relevance to clinical practice. Diet is a recommended management option for people who endure severe and distressing symptoms from antiretroviral therapy.