CONSENSUS to EMPHASIS: The overwhelming evidence which makes blockade of the reninangiotensinaldosterone system the cornerstone of therapy for systolic heart failure
Journal article
McMurray, John J. V.. (2011). CONSENSUS to EMPHASIS: The overwhelming evidence which makes blockade of the reninangiotensinaldosterone system the cornerstone of therapy for systolic heart failure. European Journal of Heart Failure. 13(9), pp. 929 - 936. https://doi.org/10.1093/eurjhf/hfr093
Authors | McMurray, John J. V. |
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Abstract | We will shortly celebrate the 25th anniversary of the publication of the Co-operative North Scandinavian Enalapril Survival Study ( CONSENSUS ), a clinical trial which revolutionized the treatment of heart failure and highlighted the importance of the renin–angiotensin–aldosterone system ( RAAS ) in the pathophysiology of heart failure ( Figure 1 ). In this article I will give a brief, historical overview of this exciting quarter-century of discovery related to the RAAS. My focus is on the treatment of heart failure in patients with a low left ventricular ejection fraction. |
Keywords | heart failure; angiotensin ii; aldosterone; angiotensin converting enzyme |
Year | 2011 |
Journal | European Journal of Heart Failure |
Journal citation | 13 (9), pp. 929 - 936 |
Publisher | John Wiley & Sons Ltd |
ISSN | 1388-9842 |
Digital Object Identifier (DOI) | https://doi.org/10.1093/eurjhf/hfr093 |
Scopus EID | 2-s2.0-80051990993 |
Page range | 929 - 936 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
Place of publication | United Kingdom |
https://acuresearchbank.acu.edu.au/item/876xw/consensus-to-emphasis-the-overwhelming-evidence-which-makes-blockade-of-the-reninangiotensinaldosterone-system-the-cornerstone-of-therapy-for-systolic-heart-failure
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