Emotion processing in persons who respond vicariously towards others in pain: Disinhibited left-lateralized neural activity for threatening expressions

Journal article


Giummarra, Melita J., Poudel, Govinda, Niu, P. Amanda, Nicholls, Michael E. R., Fielding, Joanne, Verdejo-Garcia, Antonio and Labuschagne, Izelle. (2017) Emotion processing in persons who respond vicariously towards others in pain: Disinhibited left-lateralized neural activity for threatening expressions. Laterality: Assymetries of body, brain and cognition. 23(2), pp. 184 - 208. https://doi.org/10.1080/1357650X.2017.1349781
AuthorsGiummarra, Melita J., Poudel, Govinda, Niu, P. Amanda, Nicholls, Michael E. R., Fielding, Joanne, Verdejo-Garcia, Antonio and Labuschagne, Izelle
Abstract

We investigated emotional processing in vicarious pain (VP) responders. VP responders report an explicit sensory and emotional feeling of pain when they witness another in pain, which is greater in magnitude than the empathic processing of pain in the general population. In Study 1, 31 participants completed a chimeric faces task, judging whether emotional chimera in the left, or right, visual field was more intense. VP responders took longer to judge emotionality than non-responders, and fixated more on the angry hemiface in the right visual field, whereas non-responder controls had no lateralized fixation bias. In Study 2, blood-oxygen level-dependent signals were recorded during an emotional face matching task. VP intensity was correlated with increased insula activity and reduced middle frontal gyrus activity for angry faces, and with reduced activity in the inferior and middle frontal gyri for sad faces. Together, these findings suggest that VP responders are more reactive to negative emotional expressions. Specifically, emotional judgements involved altered left-hemisphere activity in VP responders, and reduced engagement of regions involved in emotion regulation.

Keywordsemotion; distress; pain; empathy; synaesthesia
Year2017
JournalLaterality: Assymetries of body, brain and cognition
Journal citation23 (2), pp. 184 - 208
PublisherRoutledge
ISSN1357-650X
Digital Object Identifier (DOI)https://doi.org/10.1080/1357650X.2017.1349781
Scopus EID2-s2.0-85023770834
Page range184 - 208
Research GroupSchool of Philosophy
Publisher's version
File Access Level
Controlled
Place of publicationUnited Kingdom
Permalink -

https://acuresearchbank.acu.edu.au/item/87843/emotion-processing-in-persons-who-respond-vicariously-towards-others-in-pain-disinhibited-left-lateralized-neural-activity-for-threatening-expressions

Restricted files

Publisher's version

  • 12
    total views
  • 0
    total downloads
  • 0
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Delusional themes in Body Dysmorphic Disorder (BDD) : Comparisons with psychotic disorders and non-clinical Controls
Rossell, Susan L., Labuschagne, Izelle, Castle, David J. and Toh, Wei Lin. (2020) Delusional themes in Body Dysmorphic Disorder (BDD) : Comparisons with psychotic disorders and non-clinical Controls. Psychiatry Research. 284, p. 112694. https://doi.org/10.1016/j.psychres.2019.112694
Robust markers and sample sizes for multicenter trials of Huntington disease
Wijeratne, Peter A., Johnson, Eileanoir B., Eshaghi, Arman, Aksman, Leon, Gregory, Sarah, Johnson, Hans J., Poudel, Govinda R., Mohan, Amrita, Sampaio, Cristina, Georgiou-Karistianis, Nellie, Paulsen, Jane S., Tabrizi, Sarah J., Scahill, Rachael I., the Image-Hd, Predict-Hd Track-Hd investigators and Alexander, Daniel C.. (2020) Robust markers and sample sizes for multicenter trials of Huntington disease. Annals of Neurology. 87(5), pp. 751-762. https://doi.org/10.1002/ana.25709
Network diffusion modeling predicts neurodegeneration in traumatic brain injury
Poudel, Govinda R., Dominguez D, Juan F., Verhelst, Helena, Vander Linden, Catharine, Deblaere, Karel, Jones, Derek K., Cerin, Ester, Vingerhoets, Guy and Caeyenberghs, Karen. (2020) Network diffusion modeling predicts neurodegeneration in traumatic brain injury. Annals of Clinical and Translational Neurology. 7(3), pp. 270-279. https://doi.org/10.1002/acn3.50984
International Mind, Activities and Urban Places (iMAP) study: methods of a cohort study on environmental and lifestyle influences on brain and cognitive health
Ester Cerin, Anthony Barnett, Basile Chaix, Mark Nieuwenhuijsen, Karen Caeyenberghs, Bin Jalaludin, Takemi Sugiyama, James Sallis, Nicola T. Lautenschlager, Michael Y Ni, Govinda Poudel, David Donaire Gonzalez, Rachel Tham, Amanda Wheeler, Luke Knibbs, Linwei Tian, Kai Chan, David Dunstan, Alison Carver and Kaarin Anstey. (2020) International Mind, Activities and Urban Places (iMAP) study: methods of a cohort study on environmental and lifestyle influences on brain and cognitive health. BMJ Open. 10(3), pp. 1-15. https://doi.org/10.1136/bmjopen-2019-036607
Rate of torque development and striatal shape in individuals with prodromal Huntington's disease
Travis M. Cruickshank, Alvaro P. Reyes, Timothy S. Pulverenti, Tim J. Rankin, Danielle M. Bartlett, Anthony Blazevich, Govinda Poudel, Mel R. Ziman and Gabriel S Trajano. (2020) Rate of torque development and striatal shape in individuals with prodromal Huntington's disease. Scientific Reports. 10(1), pp. 1-8. https://doi.org/10.1038/s41598-020-72042-2
The effects of multidisciplinary rehabilitation on neuroimaging, biological, cognitive and motor outcomes in individuals with premanifest Huntington's disease
Danielle M. Bartlett, Andrew D. Govus, Tim J. Rankin, A. Lampit, Kirk W. Feindel, Govinda Poudel, Wei Peng Teo, Johnny Lo, Nellie Georgiou-Karistianis, Mel R. Ziman and Travis M. Cruickshank. (2020) The effects of multidisciplinary rehabilitation on neuroimaging, biological, cognitive and motor outcomes in individuals with premanifest Huntington's disease. Journal of the Neurological Sciences. 416, pp. 1-9. https://doi.org/10.1016/j.jns.2020.117022
Exploring the brain-body composition relationship in Huntington's disease
Mitchell Turner, Alvaro Reyes, Danielle M. Bartlett, Scott Culpin, Nicolas H. Hart, Luca Hardt, Kirk Feindel, Govinda R. Poudel, Mel Ziman and Travis M. Cruickshank. (2020) Exploring the brain-body composition relationship in Huntington's disease. The Journal of Musculoskeletal and Neuronal Interactions. 20(3), pp. 332-338.
Dual tasking impairments are associated with striatal pathology in Huntington’s disease
Johnny Lo, Alvaro Reyes, Timothy S. Pulverenti, Timothy J. Rankin, Danielle M. Bartlett, Pauline Zaenker, Grant Rowe, Kirk Feindel, Govinda Poudel, Nellie Georgiou-Karistianis, Mel R. Ziman and Travis M. Cruickshank. (2020) Dual tasking impairments are associated with striatal pathology in Huntington’s disease. Annals of Clinical and Translational Neurology. 7(9), pp. 1608-1619. https://doi.org/10.1002/acn3.51142
Intranasal oxytocin alters amygdala-temporal resting-state functional connectivity in body dysmorphic disorder : A double-blind placebo-controlled randomized trial
Grace, Sally A., Labuschagne, Izelle, Castle, David J. and Rossell, Susan L.. (2019) Intranasal oxytocin alters amygdala-temporal resting-state functional connectivity in body dysmorphic disorder : A double-blind placebo-controlled randomized trial. Psychoneuroendocrinology. 107, pp. 179-186. https://doi.org/10.1016/j.psyneuen.2019.05.022
Apathy associated with impaired recognition of happy facial expressions in Huntington's disease
Osborne-Crowley, Katherine, Andrews, Sophie C., Labuschagne, Izelle, Nair, Akshay, Scahill, Rachael, Craufurd, David, Tabrizi, Sarah J. and Stout, Julie C.. (2019) Apathy associated with impaired recognition of happy facial expressions in Huntington's disease. Journal of the International Neuropsychological Society. 25(5), pp. 453-461. https://doi.org/10.1017/S1355617718001224
The relationship between episodic future thinking and prospective memory in middle childhood : Mechanisms depend on task type
Terrett, Gill, Horner, Katherine, White, Roxanne, Henry, Julie D., Kliegel, Matthias, Labuschagne, Izelle and Rendell, Peter G.. (2019) The relationship between episodic future thinking and prospective memory in middle childhood : Mechanisms depend on task type. Journal of Experimental Child Psychology. 178, pp. 198-213. https://doi.org/10.1016/j.jecp.2018.10.003
The relationship between body dysmorphic disorder and obsessive-compulsive disorder: A systematic review of direct comparative studies
Malcolm, Amy, Labuschagne, Izelle, Castle, David J, Terrett, Gill, Rendell, Peter and Rossell, Susan. (2018) The relationship between body dysmorphic disorder and obsessive-compulsive disorder: A systematic review of direct comparative studies. Australian and New Zealand Journal of Psychiatry. 52(11), pp. 1030-1049. https://doi.org/10.1177/0004867418799925
Visual scanning of the eye region of human faces predicts emotion recognition performance in Huntington's disease
Catarina C. Kordsachia, Izelle Labuschagne and Julie C Stout. (2018) Visual scanning of the eye region of human faces predicts emotion recognition performance in Huntington's disease. Neuropsychology. 32(3), pp. 356-365. https://doi.org/10.1037/neu0000424
Oxytocin selectively modulates brain processing of disgust in Huntington's disease gene carriers
Izelle Labuschagne, Govinda Poudel, Catarina C. Kordsachia, Qizhu Wu, Hannah Thomson, Nellie Georgiou-Karistianis and Julie C Stout. (2018) Oxytocin selectively modulates brain processing of disgust in Huntington's disease gene carriers. Progress in Neuropsychopharmacology and Biological Psychiatry. 81, pp. 11-16. https://doi.org/10.1016/j.pnpbp.2017.09.023
Oxytocin and brain activity in humans: A systematic review and coordinate-based meta-analysis of functional MRI studies
Sally A. Grace, Susan Rossell, Markus Heinrichs, Catarina C. Kordsachia and Izelle Labuschagne. (2018) Oxytocin and brain activity in humans: A systematic review and coordinate-based meta-analysis of functional MRI studies. Psychoneuroendocrinology. 96, pp. 6-24. https://doi.org/10.1016/j.psyneuen.2018.05.031
Intranasal oxytocin does not reduce age-related difficulties in social cognition
Sarah A. Grainger, Julie Henry, Henriette R. Steinvik, Eric J Vanman, Peter Rendell and Izelle Labuschagne. (2018) Intranasal oxytocin does not reduce age-related difficulties in social cognition. Hormones and Behaviour. 99, pp. 25-34. https://doi.org/10.1016/j.yhbeh.2018.01.009
Diminished facial EMG responses to disgusting scenes and happy and fearful faces in Huntington's disease
Catarina C. Kordsachia, Izelle Labuschagne, Sophie C. Andrews and Julie C. Stout. (2018) Diminished facial EMG responses to disgusting scenes and happy and fearful faces in Huntington's disease. Cortex. 106, pp. 185-199. https://doi.org/10.1016/j.cortex.2018.05.019
Decision-making, somatic markers and emotion processing in opiate users
Kathryn Biernacki, Gill Terrett, Skye McLennan, Izelle Labuschagne, Phoebe Morton and Peter Rendell. (2018) Decision-making, somatic markers and emotion processing in opiate users. Psychopharmacology. 235(1), pp. 223-232. https://doi.org/10.1007/s00213-017-4760-0
Brief Report: The Impact of Sensory Hypersensitivity and Intolerance of Uncertainty on Anxiety in Williams Syndrome
Mirko Uljarević, Izelle Labuschagne, Rebecca Bobin, Anna Atkinson and Darren R. Hocking. (2018) Brief Report: The Impact of Sensory Hypersensitivity and Intolerance of Uncertainty on Anxiety in Williams Syndrome. Journal of Autism and Developmental Disorders. 48(11), pp. 3958-3964. https://doi.org/10.1007/s10803-018-3631-9
Intranasal oxytocin reduces heart rate variability during a mental arithmetic task: A randomised, double-blind, placebo-controlled cross-over study
Tracy, Lincoln M., Gibson, Stephen J., Labuschagne, Izelle, Georgiou-Karistianis, Nellie and Giummarra, Melita J.. (2018) Intranasal oxytocin reduces heart rate variability during a mental arithmetic task: A randomised, double-blind, placebo-controlled cross-over study. Progress in Neuropsychopharmacology and Biological Psychiatry. 81, pp. 408 - 415. https://doi.org/10.1016/j.pnpbp.2017.08.016
A critical review of brain and cognitive reserve in Huntington's disease
Soloveva, Maria V., Jamadar, Sharna D., Poudel, Govinda and Georgiou-Karistianis, Nellie. (2018) A critical review of brain and cognitive reserve in Huntington's disease. Neuroscience and Biobehavioral Reviews. 88, pp. 155 - 169. https://doi.org/10.1016/j.neubiorev.2018.03.003
Temporal evolution of neutral activity and connectivity during microsleeps when rested and following sleep restriction
Poudel, Govinda, Innes, Carrie R. H. and Jones, Richard. (2018) Temporal evolution of neutral activity and connectivity during microsleeps when rested and following sleep restriction. NeuroImage. 174, pp. 263 - 273. https://doi.org/10.1016/j.neuroimage.2018.03.031
Families affected by Huntington's Disease report difficulties in communication, emotional involvement, and problem solving
Jona, Celine M. H., Labuschagne, Izelle, Mercieca, Emily-Clare, Fisher, Fiona, Gluyas, Cathy, Stout, Julie C. and Andrews, Sophie C.. (2017) Families affected by Huntington's Disease report difficulties in communication, emotional involvement, and problem solving. Journal of Huntington's Disease. 6(3), pp. 169-177. https://doi.org/10.3233/JHD-170250
Sex-specific effects of intranasal oxytocin on thermal pain perception: A randomised, double-blind, placebo-controlled cross-over study
Tracy, Lincoln M., Labuschagne, Izelle, Georgiou-Karistianis, Nellie, Gibson, Stephen J. and Giummarra, Melita J.. (2017) Sex-specific effects of intranasal oxytocin on thermal pain perception: A randomised, double-blind, placebo-controlled cross-over study. Psychoneuroendocrinology. 83, pp. 101 - 110. https://doi.org/10.1016/j.psyneuen.2017.05.028
Beyond emotion recognition deficits: A theory guided analysis of emotion processing in Huntington's disease
Kordsachia, Catarina C., Labuschagne, Izelle and Stout, Julie C.. (2017) Beyond emotion recognition deficits: A theory guided analysis of emotion processing in Huntington's disease. Neuroscience and Biobehavioral Reviews. 73, pp. 276 - 292. https://doi.org/10.1016/j.neubiorev.2016.11.020
Impairments in spatiotemporal gait adaptation during obstacle navigation in Huntington’s disease
Anwar, Naznine, Labuschagne, Izelle, Simpson, Katrina, Smith, Luke and Georgiou-Karistianis, Nellie. (2017) Impairments in spatiotemporal gait adaptation during obstacle navigation in Huntington’s disease. Neurorehabilitation and Neural Repair. 31(10-11), pp. 934 - 943. https://doi.org/10.1177/1545968317736818
Abnormal visual scanning of emotionally evocative natural scenes in Huntington's disease
Kordsachia, Catarina C., Labuschagne, Izelle and Stout, Julie C.. (2017) Abnormal visual scanning of emotionally evocative natural scenes in Huntington's disease. Frontiers in Psychology. 8(March), pp. 1 - 10. https://doi.org/10.3389/fpsyg.2017.00405
White matter predicts functional connectivity in premanifest Huntington's disease
McColgan, Peter, Gregory, Sarah, Razi, Adeel, Seunarine, Kiran K., Gargouri, Fatma, Durr, Alexandra, Roos, Raymund A. C., Leavitt, Blair R., Scahill, Rachael I., Clark, Chris A., Tabrizi, Sarah J., Rees, Geraint, Coleman, Allison J., Decolongon, J., Fan, M., Petkau, T., Jauffret, Céline, Justo, Damian, Lehericy, S., ... Johnson, H.. (2017) White matter predicts functional connectivity in premanifest Huntington's disease. Annals of Clinical and Translational Neurology. 4(2), pp. 106 - 118. https://doi.org/10.1002/acn3.384
The neurobiology of body dysmorphic disorder: A systematic review and theoretical model
Grace, Sally A., Labuschagne, Izelle, Kaplan, Ryan A. and Rossell, Susan L.. (2017) The neurobiology of body dysmorphic disorder: A systematic review and theoretical model. Neuroscience and Biobehavioral Reviews. 83, pp. 83 - 96. https://doi.org/10.1016/j.neubiorev.2017.10.003
Neural correlates of decision-making during a Bayesian choice task
Poudel, Govinda, Bhattarai, Anjan, Dickinson, David L. and Drummond, Sean P. A.. (2017) Neural correlates of decision-making during a Bayesian choice task. NeuroReport. 28(4), pp. 193 - 199. https://doi.org/10.1097/WNR.0000000000000730
Longitudinal changes in the fronto-striatal network are associated with executive dysfunction and behavioral dysregulation in Huntington's disease: 30 months IMAGE-HD data
Dominguez, Juan F., Poudel, Govinda, Stout, Julie C., Gray, Marcus, Chua, Phyllis, Borowsky, Beth, Egan, Gary F. and Georgiou-Karistianis, Nellie. (2017) Longitudinal changes in the fronto-striatal network are associated with executive dysfunction and behavioral dysregulation in Huntington's disease: 30 months IMAGE-HD data. Cortex. 92, pp. 139 - 149. https://doi.org/10.1016/j.cortex.2017.04.001
Identification of genetic variants associated with Huntington's disease progression: A genome-wide association study
Hensman Moss, Davina J., Pardiñas, Antonio F., Langbehn, Douglas, Lo, Kitty, Leavitt, Blair R., Roos, Raymund, Durr, Alexandra, Mead, Simon, TRACK-HD investigators, , REGISTRY investigators, , Labuschagne, Izelle, TRACK-HD investigators and REGISTRY investigators. (2017) Identification of genetic variants associated with Huntington's disease progression: A genome-wide association study. The Lancet Neurology. 16(9), pp. 701 - 711. https://doi.org/10.1016/S1474-4422(17)30161-8
Fronto-cerebellar dysfunction and dysconnectivity underlying cognition in Friedreich Ataxia: The IMAGE-FRDA Study
Harding, Ian H., Corben, Louise A., Storey, Elsdon, Egan, Gary F., Stagnitti, Monique R., Poudel, Govinda, Delatycki, Martin B. and Georgiou-Karistianis, Nellie. (2016) Fronto-cerebellar dysfunction and dysconnectivity underlying cognition in Friedreich Ataxia: The IMAGE-FRDA Study. Human Brain Mapping. 37(1), pp. 338 - 350. https://doi.org/10.1002/hbm.23034
Large-scale comparative visualisation of sets of multidimensional data
Vohl, Dany, Barnes, David G., Fluke, Christopher J., Poudel, Govinda, Georgiou-Karistianis, Nellie, Hassan, Amr H., Benovitski, Yuri, Wong, Tsz Ho, Kaluza, Owen L., Nguyen, Toan D. and Bonnington, C. Paul. (2016) Large-scale comparative visualisation of sets of multidimensional data. PeerJ. 2016(10), pp. 1 - 36. https://doi.org/10.7717/peerj-cs.88
Iron accumulation in the basal ganglia in Huntington's disease: Cross-sectional data from the IMAGE-HD study
Dominguez, Juan F., Ng, Amanda C. L., Poudel, Govinda, Stout, Julie C., Churchyard, A., Chua, Phyllis, Egan, Gary F. and Georgiou-Karistianis, Nellie. (2016) Iron accumulation in the basal ganglia in Huntington's disease: Cross-sectional data from the IMAGE-HD study. Journal of Neurology, Neurosurgery and Psychiatry. 87(5), pp. 545 - 549. https://doi.org/10.1136/jnnp-2014-310183
Subjective sleep problems in Huntington's disease: A pilot investigation of the relationship to brain structure, neurocognitive, and neuropsychiatric function
Baker, Chaya Rochel, Dominguez, Juan F., Stout, Julie C., Gabery, Sanaz, Churchyard, A., Chua, Phyllis, Egan, Gary F., Petersen, Asa, Georgiou-Karistianis, Nellie and Poudel, Govinda. (2016) Subjective sleep problems in Huntington's disease: A pilot investigation of the relationship to brain structure, neurocognitive, and neuropsychiatric function. Journal of the Neurological Sciences. 364, pp. 148 - 153. https://doi.org/10.1016/j.jns.2016.03.021
Microsleeps are associated with stage-2 sleep spindles from hippocampal-temporal network
Jonmohamadi, Yaqub, Poudel, Govinda, Innes, Carrie C. R. H. and Jones, Richard. (2016) Microsleeps are associated with stage-2 sleep spindles from hippocampal-temporal network. International Journal of Neural Systems. 26(4), pp. 1 - 12. https://doi.org/10.1142/S0129065716500155
The wisdom to know the difference: Strategy-situation fit in emotion regulation in daily life is associated with well-being
Haines, Simon, Gleeson, John, Kuppens, Peter, Hollenstein, Tom, Ciarrochi, Joseph, Labuschagne, Izelle, Grace, Caitlin Claire and Koval, Peter. (2016) The wisdom to know the difference: Strategy-situation fit in emotion regulation in daily life is associated with well-being. Psychological Science. 27(12), pp. 1651 - 1659. https://doi.org/10.1177/0956797616669086
Multimodal imaging biomarkers in premanifest and early Huntington's disease: 30-month IMAGE-HD data
Dominguez, Juan, Stout, Julie C., Poudel, Govinda, Churchyard, Andrew, Chua, Phyllis, Egan, Gary F. and Georgiou-Karistianis, Nellie. (2016) Multimodal imaging biomarkers in premanifest and early Huntington's disease: 30-month IMAGE-HD data. British Journal of Psychiatry. 208(6), pp. 571 - 578. https://doi.org/10.1192/bjp.bp.114.156588
Time-varying effective connectivity of the cortical neuroelectric activity associated with behavioural microsleeps
Toppi, Jlenia, Astolfi, Laura, Poudel, Govinda, H., Babiloni, Fabio, Jones, Richard and Innes, Carrie R. H.. (2016) Time-varying effective connectivity of the cortical neuroelectric activity associated with behavioural microsleeps. NeuroImage. 124, pp. 421 - 432. https://doi.org/10.1016/j.neuroimage.2015.08.059
Improving research standards to restore trust in intranasal oxytocin
Carson, Dean S., Yuan, Hsiangkuo and Labuschagne, Izelle. (2016) Improving research standards to restore trust in intranasal oxytocin. Biological Psychiatry. 79(8), pp. e53 - e54. https://doi.org/10.1016/j.biopsych.2015.08.031
Effects of oxytocin and genetic variants on brain and behaviour : Implications for treatment in schizophrenia
Bartholomeusz, Cali, Ganella, Eleni, Labuschagne, Izelle, Bousman, Chad and Pantelis, Christos. (2015) Effects of oxytocin and genetic variants on brain and behaviour : Implications for treatment in schizophrenia. Schizophrenia Research. 168(3), pp. 614 - 627. https://doi.org/10.1016/j.schres.2015.06.007
Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder
Gorka, Stephanie M., Fitzgerald, Daniel A., Labuschagne, Izelle, Hosanagar, Avinash, Wood, Amanda G., Nathan, Pradeep J. and Phan, K. Luan. (2015) Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder. Neuropsychopharmacology. 40(2), pp. 278 - 286. https://doi.org/10.1038/npp.2014.168
Detection of motor changes in huntington's disease using dynamic causal modeling
Minkova, Lora, Scheller, Elisa, Peter, Jessica, Abdulkadir, Ahmed, Kaller, Christoph P., Roos, Raymund A. C., Dürr, Alexandra, Leavitt, Blair R., Tabrizi, Sarah J., Kloppel, Stefan, Coleman, Allison J., Decolongon, J., Fan, M., Koren, T., Jauffret, Céline, Justo, Damian, Lehericy, Stephane, Nigaud, Kevin, Valabrègue, Romain, ... Mills, J.. (2015) Detection of motor changes in huntington's disease using dynamic causal modeling. Frontiers in Human Neuroscience. 9, pp. 1 - 13. https://doi.org/10.3389/fnhum.2015.00634
Characterising upper limb movements in Huntington's Disease and the impact of restricted visual cues
Despard, Jessica, Ternes, Anne-Marie, Dimech-Betancourt, Bleydy, Poudel, Govinda, Churchyard, Andrew and Georgiou-Karistianis, Nellie. (2015) Characterising upper limb movements in Huntington's Disease and the impact of restricted visual cues. PLoS ONE. 10(8), pp. 1 - 18. https://doi.org/10.1371/journal.pone.0133709
Compensation in preclinical Huntington's disease: Evidence from the track-on hd study
Kloppel, Stefan, Gregory, Sarah, Scheller, Elisa, Minkova, Lora, Razi, Adeel, Durr, Alexandra, Roos, Raymund A. C., Leavitt, Blair R., Papoutsi, Marina, Landwehrmeyer, G. Bernhard, Reilmann, Ralf, Borowsky, Beth, Johnson, Hans, Mills, James A., Owen, Gail N., Stout, Julie C., Scahill, Rachael I., Long, Jeffrey D., Rees, Geraint, ... Orth, M.. (2015) Compensation in preclinical Huntington's disease: Evidence from the track-on hd study. EBioMedicine. 2(10), pp. 1420 - 1429. https://doi.org/10.1016/j.ebiom.2015.08.002
Neuropsychiatry and white matter microstructure in Huntington's Disease
Gregory, Sarah L., Scahill, Rachael I., Seunarine, Kiran K., Stopford, Cheryl, Zhang, Hui, Zhang, Jiaying, Orth, Michael, Dürr, Alexandra, Roos, Raymund A. C., Langbehn, Douglas R., Long, Jeffrey D., Johnson, Hans, Rees, Geraint, Tabrizi, Sarah J., Craufurd, David I. O., Campbell, C., Campbell, Melissa, Labuschagne, Izelle, Milchman, C., ... Campbell, Colin. (2015) Neuropsychiatry and white matter microstructure in Huntington's Disease. Journal of Huntington's Disease. 4(3), pp. 239 - 249. https://doi.org/10.3233/JHD-150160
Differential effects of social stress on laboratory-based decision-making are related to both impulsive personality traits and gender
Wise, Richard J., Phung, Alissa L., Labuschagne, Izelle and Stout, Julie C.. (2015) Differential effects of social stress on laboratory-based decision-making are related to both impulsive personality traits and gender. Cognition and Emotion. 29, pp. 1475 - 1485. https://doi.org/10.1080/02699931.2014.989815
Safety, tolerability, and efficacy of PBT2 in Huntington's disease: A phase 2, randomised, double-blind, placebo-controlled trial
Angus, D., Herd, C., Stone, C., Stout, Julie, Wieler, Marguerite, Reilmann, Ralf, Ritchie, C. W., Dorsey, Earl Ray, Helles, K., Kayson, Elise, Oakes, David, Rosas, Herminia Diana, Vaughan, Carr J., Panegyres, Peter K., Ames, David J., Goh, Anita, Agarwal, Pinky, Churchyard, Andrew, Murathodizic, M., ... Targum, S.. (2015) Safety, tolerability, and efficacy of PBT2 in Huntington's disease: A phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurology. 14(1), pp. 39 - 47. https://doi.org/10.1016/S1474-4422(14)70262-5
The impact of occipital lobe cortical thickness on cognitive task performance : An investigation in Huntington's Disease
Johnson, Eileanoir, Rees, Elin, Labuschagne, Izelle, Durr, Alexandra, Leavitt, Blair, Roos, Raymund, Reilmann, Ralf, Johnson, Hans, Hobbs, Nicola, Langbehn, Douglas, Stout, Julie, Tabrizi, Sarah and Scahill, Rachael. (2015) The impact of occipital lobe cortical thickness on cognitive task performance : An investigation in Huntington's Disease. Neuropsychologia. 79, pp. 138 - 146. https://doi.org/10.1016/j.neuropsychologia.2015.10.033
Comparison of beamformers for EEG source signal reconstruction
Jonmohamadi, Yaqub, Poudel, Govinda, Innes, Carrie, Weiss, Daniel, Krueger, Rejko and Jones, Richard. (2014) Comparison of beamformers for EEG source signal reconstruction. Biomedical Signal Processing and Control. 14(1), pp. 175 - 188. https://doi.org/10.1016/j.bspc.2014.07.014
Modulation of resting-state amygdala-frontal functional connectivity by oxytocin in generalized social anxiety disorder
Dodhia, Sonam, Hosanagar, Avinash, Fitzgerald, Daniel A., Labuschagne, Izelle, Wood, Amanda G., Nathan, Pradeep J. and Phan, Kinhluan Luan. (2014) Modulation of resting-state amygdala-frontal functional connectivity by oxytocin in generalized social anxiety disorder. Neuropsychopharmacology. 39(9), pp. 2061 - 2069. https://doi.org/10.1038/npp.2014.53
Source-space ICA for EEG source separation, localization, and time-course reconstruction
Jonmohamadi, Yaqub, Poudel, Govinda, Innes, Carrie and Jones, Richard. (2014) Source-space ICA for EEG source separation, localization, and time-course reconstruction. NeuroImage. 101(November), pp. 720 - 737. https://doi.org/10.1016/j.neuroimage.2014.07.052
Using theories of delusion formation to explain abnormal beliefs in Body Dysmorphic Disorder (BDD)
Rossell, Susan L., Labuschagne, Izelle, Dunai, Judith, Kyrios, Michael and Castle, David. (2014) Using theories of delusion formation to explain abnormal beliefs in Body Dysmorphic Disorder (BDD). Psychiatry Research. 215(3), pp. 599 - 605. https://doi.org/10.1016/j.psychres.2013.12.030
The Multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) high performance computing infrastructure: Applications in neuroscience and neuroinformatics research
Goscinski, Wojtek J., McIntosh, Paul, Felzmann, Ulrich, Maksimenko, Anton, Hall, Christopher J., Gureyev, Timur, Thompson, Darren, Janke, Andrew, Galloway, Graham, Killeen, Neil E. B., Raniga, Parnesh, Kaluza, Owen, Ng, Amanda, Poudel, Govinda, Barnes, David G., Nguyen, Toan, Bonnington, Paul and Egan, Gary F.. (2014) The Multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) high performance computing infrastructure: Applications in neuroscience and neuroinformatics research. Frontiers in Neuroinformatics. 8(March), pp. 1 - 13. https://doi.org/10.3389/fninf.2014.00030
The potential of composite cognitive scores for tracking progression in Huntington's disease.
Jones, Rebecca D., Stout, Julie C., Labuschagne, Izelle, Say, Miranda Julia, Justo, Damian, Coleman, Allison J., Dumas, Eve M., Hart, Ellen P., Owen, Gail N., Durr, Alexandra, Leavitt, Blair R., Roos, Raymund A. C., O'Regan, Alison M., Langbehn, Doug R., Tabrizi, Sarah J. and Frost, Chris D.. (2014) The potential of composite cognitive scores for tracking progression in Huntington's disease. Journal of Huntington's Disease. 3(2), pp. 197 - 207. https://doi.org/10.3233/JHD-140101
Functional magnetic resonance imaging of working memory in Huntington's disease: Cross-sectional data from the IMAGE-HD study
Georgiou-Karistianis, Nellie, Stout, Julie C., Domínguez, Juan F., Carron, Sarah P., Ando, Ayaka, Churchyard, Andrew, Chua, Phyllis, Bohanna, India, Dymowski, Alicia R., Poudel, Govinda and Egan, Gary F.. (2014) Functional magnetic resonance imaging of working memory in Huntington's disease: Cross-sectional data from the IMAGE-HD study. Human Brain Mapping. 35(5), pp. 1847 - 1864. https://doi.org/10.1002/hbm.22296
Voxel-ICA for reconstruction of source signal time-series and orientation in EEG and MEG
Jonmohamadi, Yaqub, Poudel, Govinda, Innes, Carrie and Jones, Richard. (2014) Voxel-ICA for reconstruction of source signal time-series and orientation in EEG and MEG. Australasian Physical and Engineering Sciences in Medicine. 37(2), pp. 457 - 464. https://doi.org/10.1007/s13246-014-0265-x
The cognitive burden in Huntington's disease: Pathology, phenotype and mechanisms of compensation
Papoutsi, Marina, Labuschagne, Izelle, Tabrizi, Sarah J. and Stout, Julie C.. (2014) The cognitive burden in Huntington's disease: Pathology, phenotype and mechanisms of compensation. Movement Disorders Society. 29(5), pp. 673 - 683. https://doi.org/10.1002/mds.25864
Multi-modal neuroimaging in premanifest and early Huntington's disease : 18 month longitudinal data from the IMAGE-HD study
Domínguez D, Juan F., Egan, Gary F., Gray, Marcus A., Poudel, Govinda R., Churchyard, Andrew, Chua, Phyllis, Stout, Julie C. and Georgiou-Karistianis, Nellie. (2013) Multi-modal neuroimaging in premanifest and early Huntington's disease : 18 month longitudinal data from the IMAGE-HD study. PLoS ONE. 8(9), pp. 1-10. https://doi.org/10.1371/journal.pone.0074131
Functional and connectivity changes during working memory in Huntington's disease : 18 month longitudinal data from the IMAGE-HD study
Georgiou-Karistianis, Nellie, Poudel, Govinda R., Domínguez D, Juan F., Langmaid, Rebecca, Gray, Marcus A., Churchyard, Andrew, Chua, Phyllis, Borowsky, Beth, Egan, Gary F. and Stout, Julie C.. (2013) Functional and connectivity changes during working memory in Huntington's disease : 18 month longitudinal data from the IMAGE-HD study. Brain and Cognition. 83(1), pp. 80-91. https://doi.org/10.1016/j.bandc.2013.07.004
Efficient and regular patterns of nighttime sleep are related to increased vulnerability to microsleeps following a single night of sleep restriction
Innes, Carrie R. H., Poudel, Govinda R. and Jones, Richard D.. (2013) Efficient and regular patterns of nighttime sleep are related to increased vulnerability to microsleeps following a single night of sleep restriction. Chronobiology International. 30(9), pp. 1187-1196. https://doi.org/10.3109/07420528.2013.810222
Distinct neural correlates of time-on-task and transient errors during a visuomotor tracking task after sleep restriction
Poudel, Govinda R., Innes, Carrie R. H. and Jones, Richard D.. (2013) Distinct neural correlates of time-on-task and transient errors during a visuomotor tracking task after sleep restriction. NeuroImage. 77, pp. 105-113. https://doi.org/10.1016/j.neuroimage.2013.03.054
A comparison of executive function in Body Dysmorphic Disorder (BDD) and Obsessive-Compulsive Disorder (OCD)
Labuschagne, Izelle, Rossell, Susan, Dunai, Judith, Castle, David and Kyrios, Michael. (2013) A comparison of executive function in Body Dysmorphic Disorder (BDD) and Obsessive-Compulsive Disorder (OCD). Journal of Obsessive-Compulsive and Related Disorders. 2(3), pp. 257 - 262. https://doi.org/10.1016/j.jocrd.2013.05.003
Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex
Sripada, Chandra, Phan, Kinhluan, Labuschagne, Izelle, Welsh, Robert, Nathan, Pradeep and Wood, Amanda. (2013) Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex. International Journal of Neuropsychopharmacology (print). 16(2), pp. 255 - 260. https://doi.org/10.1017/S1461145712000533
Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease
Labuschagne, Izelle, Jones, Rebecca, Callaghan, Jenny, Whitehead, Daisy, Dumas, Eve, Say, Miranda, Hart, Ellen, Justo, Damian, Coleman, Allison, Dar Santos, Rachelle, Frost, Chris, Craufurd, David, Trabrizi, Sarah and Stout, Julie. (2013) Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease. Psychiatry Research. 207(1-2), pp. 118 - 126. https://doi.org/10.1016/j.psychres.2012.09.022
Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease
Labuschagne, Izelle, Jones, Rebecca, Callaghan, Jenny, Whitehead, Daisy, Dumas, Eve, Say, Miranda, Hart, Ellen, Justo, Damian, Coleman, Allison, Dar Santos, Rachelle, Frost, Chris, Craufurd, David, Tabrizi, Sarah and Stout, Julie. (2013) Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease. Psychiatry Research. 207(1-2), pp. 118 - 126. https://doi.org/10.1016/j.psychres.2012.09.022
Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex
Sripada, Chandra, Phan, Kinhluan, Labuschagne, Izelle, Welsh, Robert, Nathan, Pradeep and Wood, Amanda. (2013) Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex. International Journal of Neuropsychopharmacology. 16(2), pp. 255 - 260. https://doi.org/10.1017/S1461145712000533
Time-Varying Functional Connectivity for Understanding the Neural Basis of Behavioral Microsleeps
J Toppi, L Astolfi, GR Poudel, F Babiloni, L Macchiusi, D Mattia, S Salinari and RD Jones. (2012) Time-Varying Functional Connectivity for Understanding the Neural Basis of Behavioral Microsleeps. 34th Annual International Conference of the IEEE EMBS. IEEE, Institute of Electrical and Electronics Engineers. pp. 4708-4711 https://doi.org/10.1109/EMBC.2012.6347018
Performance of Beamformers on EEG Source Reconstruction
Yaqub Jon Mohamadi, Govinda Poudel, Carrie R H Innes and Richard Jones. (2012) Performance of Beamformers on EEG Source Reconstruction. 34th Annual International Conference of the IEEE EMBS. IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/EMBC.2012.6346476
Cerebral perfusion differences between drowsy and nondrowsy individuals after acute sleep restriction
Poudel, Govinda R., Innes, Carrie R. H. and Jones, Richard D.. (2012) Cerebral perfusion differences between drowsy and nondrowsy individuals after acute sleep restriction. Sleep. 35(8), pp. 1085-1096. https://doi.org/10.5665/sleep.1994
Visual working memory impairment in premanifest gene-carriers and early Huntington's Disease
Dumas, Eve M., Say, Miranda Julia, Jones, Rebecca D., Labuschagne, Izelle, O'Regan, Alison M., Hart, Ellen P., van den Bogaard, Simon J. A., Queller, Sarah, Justo, Damian, Coleman, Allison J., dar Santos, Rachelle C., Durr, Alexandra, Leavitt, Blair R., Tabrizi, Sarah J., Roos, Raymund A. C. and Stout, Julie C.. (2012) Visual working memory impairment in premanifest gene-carriers and early Huntington's Disease. Journal of Huntington's Disease. 1(1), pp. 97 - 106. https://doi.org/10.3233/JHD-2012-120010
Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease
Stout, Julie, Jones, Rebecca, Labuschagne, Izelle, O'Regan, Alison, Say, Miranda, Dumas, Eve, Queller, Sarah, Justo, Damian, Dar Santos, Rachelle, Coleman, Allison, Hart, Ellen, Durr, Alexandra, Leavitt, Blair, Roos, Raymund, Langbehn, Doug, Tabrizi, Sarah J. and Frost, Chris. (2012) Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease. Journal of Neurology, Neurosurgery and Psychiatry. 83(7), pp. 687 - 694. https://doi.org/10.1136/jnnp-2011-301940
Medial frontal hyperactivity to sad faces in generalized social anxiety disorder and modulation by oxytocin
Labuschagne, Izelle, Phan, K. Luan, Wood, Amanda, Angstadt, Mike, Chua, Phyllis, Heinrichs, Markus, Stout, Julie C., Nathan, Pradeep J. and Pradeep, . (2012) Medial frontal hyperactivity to sad faces in generalized social anxiety disorder and modulation by oxytocin. International Journal of Neuropsychopharmacology (print). 15(7), pp. 883 - 896. https://doi.org/10.1017/S1461145711001489
Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease
Stout, Julie, Jones, Rebecca, Labuschagne, Izelle, O'Regan, Alison, Say, Miranda, Dumas, Eve, Queller, Sarah, Justo, Damian, Dar Santos, Rachelle, Coleman, Allison, Hart, Ellen, Durr, Alexandra, Leavitt, Blair, Roos, Raymund, Langbehn, Douglas, Tabrizi, Sarah J. and Frost, Chris. (2012) Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease. Journal of Neurology, Neurosurgery and Psychiatry. 83(7), pp. 687 - 694. https://doi.org/10.1136/jnnp-2011-301940
What the cognitive deficits in body dysmorphic disorder tell us about the underlying neurobiology: An investigation of three cases
Labuschagne, Izelle, Castle, David and Rossell, Susan L.. (2011) What the cognitive deficits in body dysmorphic disorder tell us about the underlying neurobiology: An investigation of three cases. International Journal of Cognitive Therapy. 4(1), pp. 21 - 33. https://doi.org/10.1521/ijct.2011.4.1.21
Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder
Labuschagne, Izelle, Phan, K. Luan, Wood, Amanda G., Angstadt, Mike, Chua, Phyllis, Heinrichs, Markus, Stout, Julie C. and Nathan, Pradeep. (2010) Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder. Neuropsychopharmacology. 35(12), pp. 2403 - 2413. https://doi.org/10.1038/npp.2010.123
Augmenting serotonin neurotransmission with citalopram modulates emotional expression decoding but not structural encoding of moderate intensity sad facial emotional stimuli: An event-related potential (ERP) investigation
Labuschagne, Izelle, Croft, Rodney, Phan, K. Luan and Nathan, Pradeep. (2010) Augmenting serotonin neurotransmission with citalopram modulates emotional expression decoding but not structural encoding of moderate intensity sad facial emotional stimuli: An event-related potential (ERP) investigation. Journal of Psychopharmacology. 24(8), pp. 1153 - 1164. https://doi.org/10.1177/0269881108097878
Executive function in body dysmorphic disorder
Dunai, Judith, Labuschagne, Izelle, Castle, David J., Kyrios, Michael and Rossell, Susan. (2010) Executive function in body dysmorphic disorder. Psychological Medicine. 40(9), pp. 1541 - 1548. https://doi.org/10.1017/S003329170999198X
An examination of delusional thinking and cognitive styles in body dysmorphic disorder
Labuschagne, Izelle, Castle, David J., Dunai, Judith, Kyrios, Michael and Rossell, Susan. (2010) An examination of delusional thinking and cognitive styles in body dysmorphic disorder. Australian and New Zealand Journal of Psychiatry. 44(8), pp. 706 - 712. https://doi.org/10.3109/00048671003671007
Evidence for modulation of facial emotional processing bias during emotional expression decoding by serotonergic and noradrenergic antidepressants: An event-related potential (ERP) study
Kerestes, Rebecca, Labuschagne, Izelle, Croft, Rodney, O'Neill, Barry, Bhagwagar, Zubin M., Phan, K Luan and Nathan, Pradeep. (2009) Evidence for modulation of facial emotional processing bias during emotional expression decoding by serotonergic and noradrenergic antidepressants: An event-related potential (ERP) study. Psychopharmacology. 202(4), pp. 621 - 634. https://doi.org/10.1007/s00213-008-1340-3