Validation of a blood marker for plasma volume in endurance athletes during a live-high train-low altitude training camp

Journal article


Lobigs, Louisa M., Garvican-Lewis, Laura A., Vuong, Victor L., Tee, Nicolin, Gore, Christopher J., Peeling, Peter, Dawson, Brian and Schumacher, Yorck O.. (2018). Validation of a blood marker for plasma volume in endurance athletes during a live-high train-low altitude training camp. Drug Testing and Analysis. 10(7), pp. 1176 - 1183. https://doi.org/10.1002/dta.2370
AuthorsLobigs, Louisa M., Garvican-Lewis, Laura A., Vuong, Victor L., Tee, Nicolin, Gore, Christopher J., Peeling, Peter, Dawson, Brian and Schumacher, Yorck O.
Abstract

Altitude is a confounding factor within the Athlete Biological Passport (ABP) due, in part, to the plasma volume (PV) response to hypoxia. Here, a newly developed PV blood test is applied to assess the possible efficacy of reducing the influence of PV on the volumetric ABP markers; haemoglobin concentration ([Hb]) and the OFF‐score. Endurance athletes (n=34) completed a 21‐night simulated live‐high train‐low (LHTL) protocol (14 h.d‐1 at 3000 m). Bloods were collected twice pre‐altitude; at days 3, 8, and 15 at altitude; and 1, 7, 21, and 42 days post‐altitude. A full blood count was performed on the whole blood sample. Serum was analysed for transferrin, albumin, calcium, creatinine, total protein, and low‐density lipoprotein. The PV blood test (consisting of the serum markers, [Hb] and platelets) was applied to the ABP adaptive model and new reference predictions were calculated for [Hb] and the OFF‐score, thereby reducing the PV variance component. The PV correction refined the ABP reference predictions. The number of atypical passport findings (ATPFs) for [Hb] was reduced from 7 of 5 subjects to 6 of 3 subjects. The OFF‐score ATPFs increased with the PV correction (from 9 to 13, 99% specificity); most likely the result of more specific reference limit predictions combined with the altitude‐induced increase in red cell production. Importantly, all abnormal biomarker values were identified by a low confidence value. Although the multifaceted, individual physiological response to altitude confounded some results, the PV model appears capable of reducing the impact of PV fluctuations on [Hb].

KeywordsAthlete Biological Passport; Bayesian inference; biological variation; blood doping; intravascular volumes
Year2018
JournalDrug Testing and Analysis
Journal citation10 (7), pp. 1176 - 1183
PublisherJohn Wiley & Sons
ISSN1942-7603
Digital Object Identifier (DOI)https://doi.org/10.1002/dta.2370
Scopus EID2-s2.0-85044717603
Open accessOpen access
Page range1176 - 1183
Research GroupMary MacKillop Institute for Health Research
Author's accepted manuscript
Publisher's version
Additional information

This is the peer reviewed version of the following article: Lobigs, LM, Garvican‐Lewis, LA, Vuong, VL, et al. Validation of a blood marker for plasma volume in endurance athletes during a live‐high train‐low altitude training camp. Drug Test Anal. 2018; 10: 1176– 1183, which has been published in final form at https://onlinelibrary.wiley.com/doi/full/10.1002/dta.2370 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

Place of publicationUnited Kingdom
Permalink -

https://acuresearchbank.acu.edu.au/item/8784v/validation-of-a-blood-marker-for-plasma-volume-in-endurance-athletes-during-a-live-high-train-low-altitude-training-camp

  • 93
    total views
  • 270
    total downloads
  • 2
    views this month
  • 3
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Short-term very high carbohydrate diet and gut-training have minor effects on gastrointestinal status and performance in highly trained endurance athletes
King, Andrew J., Etxebarria, Naroa, Ross, Megan L., Garvican-Lewis, Laura, Heikura, Ida A., McKay, Alannah K. A., Tee, Nicolin, Forbes, Sara F., Beard, Nicole A., Saunders, Philo U., Sharma, Avish P., Gaskell, Stephanie K., Costa, Ricardo J. S. and Burke, Louise M.. (2022). Short-term very high carbohydrate diet and gut-training have minor effects on gastrointestinal status and performance in highly trained endurance athletes. Nutrients. 14(9), p. Article 1929. https://doi.org/10.3390/nu14091929
A multi-parametric approach to remove the influence of plasma volume on the athlete biological passport during a Union Cycliste Internationale cycling stage race
Lewis, Laura, Lobigs, Louisa M., Equey, Tristan, Goebel, Catrin, Agon, Vanessa, McCowan, Andrew, Speers, Naomi and Schumacher, Yorck. (2020). A multi-parametric approach to remove the influence of plasma volume on the athlete biological passport during a Union Cycliste Internationale cycling stage race. Drug Testing and Analysis. 12(9), pp. 1252-1263. https://doi.org/10.1002/dta.2878
Nutrition and Altitude: Strategies to Enhance Adaptation, Improve Performance and Maintain Health: A Narrative Review
Trent Stellingwerff, Peter Peeling, Laura Lewis, Rebecca Hall, Anu Koivisto, Ida A Heikura and Louise Burke. (2019). Nutrition and Altitude: Strategies to Enhance Adaptation, Improve Performance and Maintain Health: A Narrative Review. Sports Medicine. 49, pp. 169-184. https://doi.org/10.1007/s40279-019-01159-w
Iron considerations for the athlete : A narrative review
Marc Sim, Garvican-Lewis, Laura A., Cox, Gregory R., Govus, Andrew D., McKay, Alannah K. A., Stellingwerff, T. and Peeling, Peter. (2019). Iron considerations for the athlete : A narrative review. European Journal of Applied Physiology. 119(7), pp. 1463-1478. https://doi.org/10.1007/s00421-019-04157-y
Characterizing the plasma metabolome during 14 days of live-high, train-low simulated altitude: A metabolomic approach
Lawler, Nathan G., Abbiss, Chris R., Gummer, Joel P. A., Broadhurst, David I., Govus, Andrew D., Fairchild, Timothy J., Thompson, Kevin G., Garvican-Lewis, Laura A., Gore, Christopher J., Maker, Garth L., Trengove, Robert D. and Peiffer, Jeremiah J.. (2019). Characterizing the plasma metabolome during 14 days of live-high, train-low simulated altitude: A metabolomic approach. Experimental Physiology. 104(1), pp. 81 - 92. https://doi.org/10.1113/EP087159
Nutrition and altitude: Strategies to enhance adaptation, improve performance and maintain health: A narrative review
Stellingwerff, Trent, Peeling, Peter, Garvican‑Lewis, Laura A., Hall, Rebecca, Koivisto, Anu E., Heikura, Ida A. and Burke, Louise M.. (2019). Nutrition and altitude: Strategies to enhance adaptation, improve performance and maintain health: A narrative review. Sports Medicine. 49(Supplement 2), pp. 169 - 184. https://doi.org/10.1007/s40279-019-01159-w
Special environments: Altitude and heat
Saunders, Philo U., Garvican-Lewis, Laura A., Chapman, Robert F. and Périard, Julien D.. (2019). Special environments: Altitude and heat. International Journal of Sport Nutrition and Exercise Metabolism. 29(2), pp. 210 - 219. https://doi.org/10.1123/ijsnem.2018-0256
Training to compete at altitude: Natural altitude or simulated live high: train low?
Carr, Amelia J., Garvican-Lewis, Laura A., Vallance, Brent S., Drake, Andrew P., Saunders, Philo U., Humberstone, Clare E. and Gore, Christopher J.. (2019). Training to compete at altitude: Natural altitude or simulated live high: train low? International Journal of Sports Physiology and Performance. 14(4), pp. 509 - 517. https://doi.org/10.1123/ijspp.2018-0099
The potential to change pacing and performance during 4000-m cycling time trials using hyperoxia and inspired gas-content deception
Davies, Michael J., Clark, Bradley, Garvican-Lewis, Laura A., Welvaert, Marijke, Gore, Christopher J. and Thompson, Kevin G.. (2019). The potential to change pacing and performance during 4000-m cycling time trials using hyperoxia and inspired gas-content deception. International Journal of Sports Physiology and Performance. 14(7), pp. 949 - 957. https://doi.org/10.1123/ijspp.2018-0335
Acute carbohydrate ingestion does not influence the post-exercise iron-regulatory response in elite keto-adapted race walkers
McKay, Alannah K. A., Peeling, Peter, Pyne, David B., Welvaert, Marijke, Tee, Nicolin, Leckey, Jill J., Sharma, Avish P., Ross, Megan L. R., Garvican-Lewis, Laura A., van Swelm, Rachel P. L., Laarakkers, Coby M. and Burke, Louise M.. (2019). Acute carbohydrate ingestion does not influence the post-exercise iron-regulatory response in elite keto-adapted race walkers. Journal of Science and Medicine in Sport. 22(6), pp. 635 - 640. https://doi.org/10.1016/j.jsams.2018.12.015
Improved performance in national-level runners with increased training load at 1600 and 1800 m
Sharma, Avish P., Saunders, Philo U., Garvican-Lewis, Laura A., Clark, Brad, Welvaert, Marijke, Gore, Christopher J. and Thompson, Kevin G.. (2019). Improved performance in national-level runners with increased training load at 1600 and 1800 m. International Journal of Sports Physiology and Performance. 14(3), pp. 286 - 295. https://doi.org/10.1123/ijspp.2018-0104
Chronic adherence to a ketogenic diet modifies iron metabolism in elite athletes
McKay, Alannah K.A., Peeling, Peter, Pyne, David B., Welvaert, Marijke, Tee, Nicolin, Leckey, Jill J., Sharma, Avish P., Ross, Megan L. R., Garvican-Lewis, Laura, Swinkels, Dorine W., Laarakkers, Coby M. and Burke, Louise M.. (2019). Chronic adherence to a ketogenic diet modifies iron metabolism in elite athletes. Medicine and Science in Sports and Exercise. 51(3), pp. 548 - 555. https://doi.org/10.1249/MSS.0000000000001816
Normobaric hypoxia reduces VO2 at different intensities in highly trained runners
Sharma, Avish P., Saunders, Philo U., Garvican-Lewis, Laura A., Clark, Bradley, Gore, Christopher J., Thompson, Kevin G. and Periard, Julien D.. (2019). Normobaric hypoxia reduces VO2 at different intensities in highly trained runners. Medicine and Science in Sports and Exercise. 51(1), pp. 174 - 182. https://doi.org/10.1249/MSS.0000000000001745
The effects of intensified training on resting metabolic rate (RMR), body composition and performance in trained cyclists
Woods, Amy L., Rice, Anthony J., Garvican-Lewis, Laura A., Wallett, Alice M., Lundy, Bronwen, Rogers, Margot A., Welvaert, Marijke, Halson, Shona, McKune, Andrew and Thompson, Kevin G.. (2018). The effects of intensified training on resting metabolic rate (RMR), body composition and performance in trained cyclists. PLoS ONE. 13(2), pp. 1 - 24. https://doi.org/10.1371/journal.pone.0191644
Influence of combined iron supplementation and simulated hypoxia on the haematological module of the athlete biological passport
Garvican-Lewis, Laura A., Vuong, Victor L., Govus, Andrew D., Schumacher, Yorck O., Hughes, David, Lovell, Greg, Eichner, Daniel and Gore, Christopher J.. (2018). Influence of combined iron supplementation and simulated hypoxia on the haematological module of the athlete biological passport. Drug Testing and Analysis. 10(4), pp. 731 - 741. https://doi.org/10.1002/dta.2303
Training quantification and periodization during live high train high at 2100 M in elite runners: an observational cohort case study
Sharma, Avish P., Saunders, Philo U., Garvican-Lewis, Laura A., Périard, Julien E., Clark, Brad, Gore, Christopher J., Raysmith, Benjamin P., Stanley, Jamie, Robertson, Eileen Y. and Thompson, Kevin G.. (2018). Training quantification and periodization during live high train high at 2100 M in elite runners: an observational cohort case study. Journal of Sports Science and Medicine. 17(4), pp. 607 - 616.
Effect of intensified endurance training on pacing and performance in 4000-m cycling time trials
Wallett, Alice M., Woods, Amy L., Versey, Nathan, Garvican-Lewis, Laura A., Welvaert, Marijke and Thompson, Kevin G.. (2018). Effect of intensified endurance training on pacing and performance in 4000-m cycling time trials. International Journal of Sports Physiology and Performance. 13(6), pp. 735 - 741. https://doi.org/10.1123/ijspp.2017-0287
Intravenous iron does not augment the hemoglobin mass response to simulated hypoxia
Garvican-Lewis, Laura A., Vuong, Victor L., Govus, Andrew D., Peeling, Peter, Jung, Grace, Nemeth, Elizabeta, Hughes, David, Lovell, Gregory, Eichner, Daniel and Gore, Christopher J.. (2018). Intravenous iron does not augment the hemoglobin mass response to simulated hypoxia. Medicine and Science in Sports and Exercise. 50(8), pp. 1669 - 1678. https://doi.org/10.1249/MSS.0000000000001608
The athlete's hematological response to hypoxia: a meta-analysis on the influence of altitude exposure on key biomarkers of erythropoiesis
Lobigs, Louisa M., Sharpe, Ken, Garvican-Lewis, Laura A., Gore, Christopher J., Peeling, Peter, Dawson, Brian and Schumacher, Yorck O.. (2018). The athlete's hematological response to hypoxia: a meta-analysis on the influence of altitude exposure on key biomarkers of erythropoiesis. American Journal of Hematology. 93(1), pp. 74 - 83. https://doi.org/10.1002/ajh.24941
Sleep at the helm: a case study of how a head coach sleeps compared to his team
Lastella, M., Roach, G. D., Halson, S. L., Gore, C. J., Garvican-Lewis, L. A. and Sargent, C.. (2017). Sleep at the helm: a case study of how a head coach sleeps compared to his team. International Journal of Sports Science and Coaching. 12(6), pp. 782 - 789. https://doi.org/10.1177/1747954117738882
12 days of altitude exposure at 1800 m does not increase resting metabolic rate in elite rowers
Woods, Amy L., Garvican-Lewis, Laura A., Rice, Anthony J. and Thompson, Kevin G.. (2017). 12 days of altitude exposure at 1800 m does not increase resting metabolic rate in elite rowers. Applied Physiology, Nutrition and Metabolism. 42(6), pp. 672-676. https://doi.org/10.1139/apnm-2016-0693
Four weeks of classical altitude training increases resting metabolic rate in highly trained middle-distance runners
Woods, Amy L., Sharma, Avish P., Garvican-Lewis, Laura A., Saunders, Philo U., Rice, Anthony J. and Thompson, Kevin G.. (2017). Four weeks of classical altitude training increases resting metabolic rate in highly trained middle-distance runners. International Journal of Sport Nutrition and Exercise Metabolism. 26(1), pp. 83 - 90. https://doi.org/10.1123/ijsnem.2016-0116
Live high, train low – influence on resting and post-exercise hepcidin levels
Govus, Andrew D., Peeling, P., Abbiss, C R., Lawler, N. G., Swinkels, D. W., Laarakkers, C. M., Thompson, K. G., Peiffer, J. J., Gore, C. J. and Garvican-Lewis, L. A.. (2017). Live high, train low – influence on resting and post-exercise hepcidin levels. Scandinavian Journal of Medicine & Science in Sports. 27(7), pp. 704 - 713. https://doi.org/10.1111/sms.12685
The effect of training at 2100-m altitude on running speed and session rating of perceived exertion at different intensities in elite middle-distance runners
Sharma, Avish P., Saunders, Philo U., Garvican-Lewis, Laura A., Clark, Brad, Stanley, Jamie, Robertson, Eileen Y. and Thompson, Kevin G.. (2017). The effect of training at 2100-m altitude on running speed and session rating of perceived exertion at different intensities in elite middle-distance runners. International Journal of Sports Physiology and Performance. 12, pp. S2-147 - S2-152. https://doi.org/10.1123/ijspp.2016-0402
Effect of environmental and feedback interventions on pacing profiles in cycling: a meta-analysis
Davies, Michael J., Clark, Bradley, Welvaert, Marijke, Skorski, Sabrina, Lewis, Laura, Saunders, Philo and Thompson, Kevin G.. (2016). Effect of environmental and feedback interventions on pacing profiles in cycling: a meta-analysis. Frontiers in Physiology. 7, pp. 1 - 24. https://doi.org/10.3389/fphys.2016.00591
Time for a new metric for hypoxic dose?
Garvican-Lewis, Laura A., Sharpe, Ken and Gore, Christopher J.. (2016). Time for a new metric for hypoxic dose? Journal of Applied Physiology. 121(1), pp. 352 - 355. https://doi.org/10.1152/japplphysiol.00579.2015
The ventilation-corrected ParvoMedics TrueOne 2400 provides a valid and reliable assessment of resting metabolic rate (RMR) in athletes compared with the Douglas Bag Method
Woods, Amy L., Garvican-Lewis, Laura A., Rice, Anthony J. and Thompson, Kevin G.. (2016). The ventilation-corrected ParvoMedics TrueOne 2400 provides a valid and reliable assessment of resting metabolic rate (RMR) in athletes compared with the Douglas Bag Method. International Journal of Sport Nutrition and Exercise Metabolism. 26(5), pp. 454 - 463. https://doi.org/10.1123/ijsnem.2015-0315
Increased hypoxic dose after training at low altitude with 9h per night at 3000m normobaric hypoxia
Carr, A. J., Saunders, Philo, Vallance, Brent S., Lewis, Laura and Gore, Christopher J.. (2015). Increased hypoxic dose after training at low altitude with 9h per night at 3000m normobaric hypoxia. Journal of Sports Science and Medicine. 14(4), pp. 776 - 782.
Impact of altitude on power output during cycling stage racing
Lewis, Laura, Clark, Bradley, Martin, David T., Schumacher, Yorck O., McDonald, Warren, Stephens, Brian, Ma, Fuhai, Thompson, Kevin G., Gore, Christopher J. and Menaspà, Paolo. (2015). Impact of altitude on power output during cycling stage racing. PLoS ONE. 10(12), pp. 1 - 15. https://doi.org/10.1371/journal.pone.0143028
Altitude exposure at 1800 m increases haemoglobin mass in distance runners
Lewis, Laura, Halliday, Iona, Abbiss, Chris R., Saunders, Philo and Gore, Christopher J.. (2015). Altitude exposure at 1800 m increases haemoglobin mass in distance runners. Journal of Sports Science and Medicine. 14(2), pp. 413 - 417.
Relative match intensities at high altitude in highly-trained young soccer players (ISA3600)
Buchheit, M., Hammond, Kristal, Bourdon, Pitre C., Simpson, Ben M., Lewis, Laura, Schmidt, Walter F., Gore, Christopher J. and Aughey, Robert. (2015). Relative match intensities at high altitude in highly-trained young soccer players (ISA3600). Journal of Sports Science and Medicine. 14(1), pp. 98 - 102.
High altitude, prolonged exercise, and the athlete biological passport
Schumacher, Yorck O., Lewis, Laura, Christian, Ryan, Lobigs, Louisa M., Qi, Jiliang, Fan, Rongyun, He, Yingying, Wang, Hailing, Gore, Christopher J. and Ma, Fuhai. (2015). High altitude, prolonged exercise, and the athlete biological passport. Drug Testing and Analysis. 7(1), pp. 48 - 55. https://doi.org/10.1002/dta.1717
Pre-altitude serum ferritin levels and daily oral iron supplement dose mediate iron parameter and hemoglobin mass responses to altitude exposure
Govus, Andrew D., Lewis, Laura, Abbiss, Chris R., Peeling, P. and Gore, Christopher J.. (2015). Pre-altitude serum ferritin levels and daily oral iron supplement dose mediate iron parameter and hemoglobin mass responses to altitude exposure. PLoS ONE. 10(8), pp. 1 - 11. https://doi.org/10.1371/journal.pone.0135120
Lower running performance and exacerbated fatigue in soccer played at 1600 m
Lewis, Laura, Hammond, Kristal, Varley, Matthew C., Gore, Christopher J., Billaut, Francois and Aughey, Robert. (2014). Lower running performance and exacerbated fatigue in soccer played at 1600 m. International Journal of Sports Physiology and Performance. 9(3), pp. 397 - 404. https://doi.org/10.1123/IJSPP.2012-0375
Stage racing at altitude induces hemodilution despite an increase in hemoglobin mass
Lewis, Laura, Schumacher, Yorck O., Clark, Sally, Christian, Ryan, Menaspà, Paolo, Plowman, Jamie, Stephens, Brian, Qi, Jiliang, Fan, Rongyun, He, Yingying, Martin, David T., Thompson, Kevin G., Gore, Christopher J. and Ma, Fuhai. (2014). Stage racing at altitude induces hemodilution despite an increase in hemoglobin mass. Journal of Applied Physiology. 117(5), pp. 463 - 472. https://doi.org/10.1152/japplphysiol.00242.2014
Four weeks of IV iron supplementation reduces perceived fatigue and mood disturbance in distance runners
Woods, Amy L., Garvican-Lewis, Laura A., Saunders, Philo U., Lovell, Greg, Hughes, David, Fazakerley, Ruth, Anderson, Bev, Gore, Christopher J. and Thompson, Kevin G.. (2014). Four weeks of IV iron supplementation reduces perceived fatigue and mood disturbance in distance runners. PLoS ONE. 9(9), pp. 1 - 11. https://doi.org/10.1371/journal.pone.0108042
Acute hypoxic exercise does not alter post-exercise iron metabolism in moderately trained endurance athletes
Govus, Andrew D., Abbiss, Chris R., Lewis, Laura, Swinkels, Dorine W., Laarakkers, Coby M., Gore, Christopher J. and Peeling, P. (2014). Acute hypoxic exercise does not alter post-exercise iron metabolism in moderately trained endurance athletes. European Journal of Applied Physiology. 114(10), pp. 2183 - 2191. https://doi.org/10.1007/s00421-014-2938-2
Yin and yang, or peas in a pod? Individual-sport versus team-sport athletes and altitude training
Aughey, Robert J., Buchheit, Martin, Garvican-Lewis, Laura A., Roach, Gregory D., Sargent, Charli, Billaut, François, Varley, Matthew C., Bourdon, Pitre C. and Gore, Christopher J.. (2013). Yin and yang, or peas in a pod? Individual-sport versus team-sport athletes and altitude training. British Journal of Sports Medicine. 47(18), pp. 1150-1154. https://doi.org/10.1136/bjsports-2013-092764
Wellness, fatigue and physical performance acclimatisation to a 2-week soccer camp at 3600 m (ISA3600)
Buchheit, Martin, Simpson, Ben M., Garvican-Lewis, Laura A., Hammond, Kristal, Kley, Marlen, Schmidt, Walter F., Aughey, Robert J., Soria, Rudy, Sargent, Charli, Roach, Gregory D., Claros, Jesus C. Jimenez, Wachsmuth, Nadine, Gore, Christopher J. and Bourdon, Pitre C.. (2013). Wellness, fatigue and physical performance acclimatisation to a 2-week soccer camp at 3600 m (ISA3600). British Journal of Sports Medicine. 47(Suppl 1), p. i100. https://doi.org/10.1136/bjsports-2013-092749
The sleep of elite athletes at sea level and high altitude : A comparison of sea-level natives and high-altitude natives (ISA3600)
Roach, Gregory D., Schmidt, Walter F., Aughey, Robert J., Bourdon, Pitre C., Soria, Rudy, Claros, Jesus C. Jimenez, Garvican-Lewis, Laura A., Buchheit, Martin, Simpson, Ben M., Hammond, Kristal, Kley, Marlen, Wachsmuth, Nadine, Gore, Christopher J. and Sargent, Charli. (2013). The sleep of elite athletes at sea level and high altitude : A comparison of sea-level natives and high-altitude natives (ISA3600). British Journal of Sports Medicine. 47(Suppl 1), p. i114. https://doi.org/10.1136/bjsports-2013-092843
The impact of altitude on the sleep of young elite soccer players (ISA3600)
Sargent, Charli, Schmidt, Walter F., Aughey, Robert J., Bourdon, Pitre C., Soria, Rudy, Claros, Jesus C. Jimenez, Garvican-Lewis, Laura A., Buchheit, Martin, Simpson, Ben M., Hammond, Kristal, Kley, Marlen, Wachsmuth, Nadine, Gore, Christopher J. and Roach, Gregory D.. (2013). The impact of altitude on the sleep of young elite soccer players (ISA3600). British Journal of Sports Medicine. 47(Suppl 1), p. i86. https://doi.org/10.1136/bjsports-2013-092829
The effects of injury and illness on haemoglobin mass
Gough, C. E., Sharpe, K., Garvican, L. A., Anson, J. M., Saunders, P. U. and Gore, C. J.. (2013). The effects of injury and illness on haemoglobin mass. International Journal of Sports Medicine. 34(9), pp. 763-769. https://doi.org/10.1055/s-0033-1333692
The distribution of pace adopted by cyclists during a cross-country mountain bike world championships
Abbiss, Chris R., Ross, Megan L. R., Garvican, Laura A., Ross, Neil, Pottgiesser, Torben, Gregory, John and Martin, David T.. (2013). The distribution of pace adopted by cyclists during a cross-country mountain bike world championships. Journal of Sports Sciences. 31(7), pp. 787-794. https://doi.org/10.1080/02640414.2012.751118
Soccer activity profile of altitude versus sea-level natives during acclimatisation to 3600 m (ISA3600)
Aughey, Robert J., Hammond, Kristal, Varley, Matthew C., Schmidt, Walter F., Bourdon, Pitre C., Buchheit, Martin, Simpson, Ben, Garvican-Lewis, Laura A., Kley, Marlen, Soria, Rudy, Sargent, Charli, Roach, Gregory D., Claros, Jesus C. Jimenez, Wachsmuth, Nadine and Gore, Christopher J.. (2013). Soccer activity profile of altitude versus sea-level natives during acclimatisation to 3600 m (ISA3600). British Journal of Sports Medicine. 47(Suppl 1), pp. 1-7. https://doi.org/10.1136/bjsports-2013-092776
Relationship between changes in haemoglobin mass and maximal oxygen uptake after hypoxic exposure
Saunders, Philo U., Garvican-Lewis, Laura A., Schmidt, Walter F. and Gore, Christopher J.. (2013). Relationship between changes in haemoglobin mass and maximal oxygen uptake after hypoxic exposure. British Journal of Sports Medicine. 47(Suppl 1), pp. 1-6. https://doi.org/10.1136/bjsports-2013-092841
Predicting sickness during a 2-week soccer camp at 3600 m (ISA3600)
Buchheit, Martin, Simpson, Ben M., Schmidt, Walter F., Aughey, Robert J., Soria, Rudy, Hunt, Robert A., Garvican-Lewis, Laura A., Pyne, David B., Gore, Christopher J. and Bourdon, Pitre C.. (2013). Predicting sickness during a 2-week soccer camp at 3600 m (ISA3600). British Journal of Sports Medicine. 47(Suppl 1), pp. 1-4. https://doi.org/10.1136/bjsports-2013-092757
Methods of the international study on soccer at altitude 3600 m (ISA3600)
Gore, Christopher J., Aughey, Robert J., Bourdon, Pitre C., Garvican-Lewis, Laura A., Soria, Rudy, Claros, Jesus C. Jimenez, Sargent, Charli, Roach, Gregory D., Buchheit, Martin, Simpson, Ben M., Hammond, Kristal, Kley, Marlen, Wachsmuth, Nadine, Pepper, Mark, Edwards, Alistair, Cuenca, Douglas, Vidmar, Tony, Spielvogel, Hilde and Schmidt, Walter F.. (2013). Methods of the international study on soccer at altitude 3600 m (ISA3600). British Journal of Sports Medicine. 47(Supplement 1), p. i80–i85. https://doi.org/10.1136/bjsports-2013-092770
Changes in blood gas transport of altitude native soccer players near sea-level and sea-level native soccer players at altitude (ISA3600)
Wachsmuth, Nadine, Kley, Marlen, Spielvogel, Hilde, Aughey, Robert J., Gore, Christopher J., Bourdon, Pitre C., Hammond, Kristal, Sargent, Charli, Roach, Gregory D., Sanchez, Rudy Soria, Jimenez Claros, Jesus C., Schmidt, Walter F. and Garvican-Lewis, Laura A.. (2013). Changes in blood gas transport of altitude native soccer players near sea-level and sea-level native soccer players at altitude (ISA3600). British Journal of Sports Medicine. 47(Supplement 1), pp. i93-i99. https://doi.org/10.1136/bjsports-2013-092761
Altitude training and haemoglobin mass from the optimised carbon monoxide rebreathing method determined by a meta-analysis
Gore, Christopher, Sharpe, Ken, Garvican-Lewis, Laura, Saunders, Philo, Humberstone, Clare, Robertson, Eileen, Wachsmuth, Nadine, Clark, Sally, McLean, Blake and Friedmann-Bette, Birgit. (2013). Altitude training and haemoglobin mass from the optimised carbon monoxide rebreathing method determined by a meta-analysis. British Journal of Sports Medicine. https://doi.org/10.1136/bjsports-2013-092840
Time course of the hemoglobin mass response to natural altitude training in elite endurance cyclists
Garvican, L., Martin, D., Quod, M., Stephens, B. and Sassi, A.. (2012). Time course of the hemoglobin mass response to natural altitude training in elite endurance cyclists. Scandinavian Journal of Medicine & Science in Sports. 22(1), pp. 95-103. https://doi.org/10.1111/j.1600-0838.2010.01145.x
Short-term hematological effects upon completion of a four-week simulated altitude camp
Pottgiesser,Torben, Garvican, Laura A., Martin, David T., Featonby, Jesse M., Gore, Christopher J. and Schumacher, Yorck O.. (2012). Short-term hematological effects upon completion of a four-week simulated altitude camp. International Journal of Sports Physiology and Performance. 7(1), pp. 79-83. https://doi.org/10.1123/Ijspp.7.1.79
The contribution of haemoglobin mass to increases in cycling performance induced by simulated LHTL
Garvican, Laura A., Pottgiesser, Torben, Martin, David T., Schumacher, Yorck Olaf, Barras, Martin and Gore, Christopher J.. (2011). The contribution of haemoglobin mass to increases in cycling performance induced by simulated LHTL. European Journal of Applied Physiology. 111(6), pp. 1089-1101. https://doi.org/10.1007/s00421-010-1732-z
Standardising analysis of carbon monoxide rebreathing for application in anti-doping
Alexander, Anthony C., Garvican, Laura A., Burge, Caroline M., Clark, Sally A., Plowman, James S. and Gore, Christopher J.. (2011). Standardising analysis of carbon monoxide rebreathing for application in anti-doping. Journal of Science and Medicine in Sport. 14(2), pp. 100-105. https://doi.org/10.1016/j.jsams.2010.07.007
Quality control technique to reduce the variability of longitudinal measurement of hemoglobin mass
Gough, C. E., Sharpe, K., Ashenden, M. J., Anson, J. M., Saunders, P. U., Garvican, L. A., Bonetti, D. L., Gore, C. J. and Prommer, N.. (2011). Quality control technique to reduce the variability of longitudinal measurement of hemoglobin mass. Scandinavian Journal of Medicine & Science in Sports. 21(6), pp. e365-e371. https://doi.org/10.1111/j.1600-0838.2011.01316.x