Reexamining the surfaces of bone in boys and girls during adolescent growth: A 12-Year mixed longitudinal pQCT Study

Journal article


Gabel, Leigh, Nettlefold, Lindsay, Brasher, Penelope M., Moore, Sarah A., Ahamed, Yasmin, Macdonald, Heather M. and McKay, Heather A.. (2015). Reexamining the surfaces of bone in boys and girls during adolescent growth: A 12-Year mixed longitudinal pQCT Study. Journal of Bone and Mineral Research. 30(12), pp. 2158 - 2167. https://doi.org/10.1002/jbmr.2570
AuthorsGabel, Leigh, Nettlefold, Lindsay, Brasher, Penelope M., Moore, Sarah A., Ahamed, Yasmin, Macdonald, Heather M. and McKay, Heather A.
Abstract

We revisit Stanley Garn's theory related to sex differences in endocortical and periosteal apposition during adolescence using a 12-year mixed longitudinal study design. We used peripheral quantitative computed tomography to examine bone parameters in 230 participants (110 boys, 120 girls; aged 11.0 years at baseline). We assessed total (Tt.Ar, mm2), cortical (Ct.Ar, mm2), and medullary canal area (Me.Ar, mm2), Ct.Ar/Tt.Ar, cortical bone mineral density (Ct.BMD, mg/cm3), and polar strength-strain index (SSIp, mm3) at the tibial midshaft (50% site). We used annual measures of height and chronological age to identify age at peak height velocity (APHV) for each participant. We compared annual accrual rates of bone parameters between boys and girls, aligned on APHV using a linear mixed effects model. At APHV, boys demonstrated greater Tt.Ar (ratio = 1.27; 95% confidence interval [CI] 1.21, 1.32), Ct.Ar (1.24 [1.18, 1.30]), Me.Ar (1.31 [1.22, 1.40]), and SSIp (1.36 [1.28, 1.45]) and less Ct.Ar/Tt.Ar (0.98 [0.96, 1.00]) and Ct.BMD (0.97 [0.96, 0.97]) compared with girls. Boys and girls demonstrated periosteal bone formation and net bone loss at the endocortical surface. Compared with girls, boys demonstrated greater annual accrual rates pre-APHV for Tt.Ar (1.18 [1.02, 1.34]) and Me.Ar (1.34 [1.11, 1.57]), lower annual accrual rates pre-APHV for Ct.Ar/Tt.Ar (0.56 [0.29, 0.83]) and Ct.BMD (–0.07 [–0.17, 0.04]), and similar annual accrual rates pre-APHV for Ct.Ar (1.10 [0.94, 1.26]) and SSIp (1.14 [0.98, 1.30]). Post-APHV, boys demonstrated similar annual accrual rates for Ct.Ar/Tt.Ar (1.01 [0.71, 1.31]) and greater annual accrual rates for all other bone parameters compared with girls (ratio = 1.23 to 2.63; 95% CI 1.11 to 3.45). Our findings support those of Garn and others of accelerated periosteal apposition during adolescence, more evident in boys than girls. However, our findings challenge the notion of greater endocortical apposition in girls, suggesting instead that girls experience diminished endocortical resorption compared with boys

KeywordspQCT; Bone Accrual; Bone Strength; Peak Height Velocity; Growth
Year2015
JournalJournal of Bone and Mineral Research
Journal citation30 (12), pp. 2158 - 2167
PublisherWiley-Blackwell Publishing, Inc.
ISSN0884-0431
Digital Object Identifier (DOI)https://doi.org/10.1002/jbmr.2570
Scopus EID2-s2.0-84954049833
Page range2158 - 2167
Research GroupMary MacKillop Institute for Health Research
Publisher's version
File Access Level
Controlled
Place of publicationUnited States of America
EditorsJ. E.Compston
Permalink -

https://acuresearchbank.acu.edu.au/item/8799x/reexamining-the-surfaces-of-bone-in-boys-and-girls-during-adolescent-growth-a-12-year-mixed-longitudinal-pqct-study

Restricted files

Publisher's version

  • 122
    total views
  • 0
    total downloads
  • 0
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Determining brain mechanisms that underpin analgesia induced by the use of pain coping skills
Cole, Leonie J., Bennell, Kim, Ahamed, Yasmin, Pachana, Nancy A., Keefe, Francis J., Moseley, G. Lorimer, Hodges, Paul and Farrell, Michael J.. (2018). Determining brain mechanisms that underpin analgesia induced by the use of pain coping skills. Pain Medicine. 19(11), pp. 2177 - 2190. https://doi.org/10.1093/pm/pnx301
Multimorbidity and the risk of all-cause 30-day readmission in the setting of multidisciplinary management of chronic heart failure: A retrospective analysis of 830 hospitalized patients in Australia
Wiley, Joshua F., Chan, Yih-Kai, Ahamed, Yasmin, Ball, Jocasta, Carrington, Melinda J., Reigel, Barbara and Stewart, Simon. (2018). Multimorbidity and the risk of all-cause 30-day readmission in the setting of multidisciplinary management of chronic heart failure: A retrospective analysis of 830 hospitalized patients in Australia. Journal of Cardiovascular Nursing. 33(5), pp. 437 - 445. https://doi.org/10.1097/JCN.0000000000000391
Physical Therapist-Delivered Pain Coping Skills Training and Exercise for Knee Osteoarthritis: Randomized Controlled Trial
Bennell, Kim L., Ahamed, Yasmin, Jull, Gwendolen J., Bryant, Christina, Hunt, Michael A., Forbes, Andrew B., Kasza, Jessica, Akram, Muhammed, Metcalf, Ben R., Harris, Anthony, Egerton, T., Kenardy, Justin A., Nicholas, Michael K. and Keefe, Francis J.. (2016). Physical Therapist-Delivered Pain Coping Skills Training and Exercise for Knee Osteoarthritis: Randomized Controlled Trial. Arthritis Care and Research. 68(5), pp. 590 - 602. https://doi.org/10.1002/acr.22744
Establishing a pragmatic framework to optimise health outcomes in heart failure and multimorbidity (ARISE-HF): A multidisciplinary position statement
Stewart, Simon, Riegel, Barbara, Boyd, Cynthia, Ahamed, Yasmin, Thompson, David Robert, Burrell, Louise M., Carrington, Melinda Jane, Coats, Andrew, Granger, Bradi B., Hides, Julie Anne, Weintraub, William S., Moser, Debra K., Dickson, Victoria Vaughan, McDermott, Cressida J., Keates, Ashley K. and Rich, Michael W.. (2016). Establishing a pragmatic framework to optimise health outcomes in heart failure and multimorbidity (ARISE-HF): A multidisciplinary position statement. International Journal of Cardiology. 212, pp. 1 - 10. https://doi.org/10.1016/j.ijcard.2016.03.001
Current and projected burden of heart failure in the Australian adult population: A substantive but still ill-defined major health issue
Chan, Yih-Kai, Tuttle, Camilla, Ball, Jocasta C., Teng, Tiew-Hwa Katherine, Ahamed, Yasmin, Carrington, Melinda Jane and Stewart, Simon. (2016). Current and projected burden of heart failure in the Australian adult population: A substantive but still ill-defined major health issue. BMC Health Services Research. 16(501), pp. 1 - 10. https://doi.org/10.1186/s12913-016-1748-0
Impact of nurse-led, multidisciplinary home-based intervention on event-free survival across the spectrum of chronic heart disease: Composite analysis of health outcomes in 1226 patients from 3 randomized trials
Stewart, Simon, Wiley, Joshua F., Ball, Jocasta Clare, Chan, Yih-Kai, Ahamed, Yasmin, Thompson, David Robert and Carrington, Melinda Jane. (2016). Impact of nurse-led, multidisciplinary home-based intervention on event-free survival across the spectrum of chronic heart disease: Composite analysis of health outcomes in 1226 patients from 3 randomized trials. Circulation. 133(19), pp. 1867 - 1877. https://doi.org/10.1161/CIRCULATIONAHA.116.020730
Rediscovering Heart Failure: The contemporary burden and profile of heart failure in Australia
Chan, Yih-Kai, Gerber, Tracey, Tuttle, Camilla, Ball, Jocasta, Teng, Tiew-Hwa Katherine, Ahamed, Yasmin and Carrington, Melinda. (2015). Rediscovering Heart Failure: The contemporary burden and profile of heart failure in Australia Melbourne, Australia: Mary MacKillop Institute for Health Research.
Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes
Bryant, Christina, Lewis, Prudence, Bennell, Kim, Ahamed, Yasmin, Crough, Denae, Jull, Gwendolen, Kenardy, Justin, Nicholas, Michael and Keefe, Francis. (2014). Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes. Physical Therapy. 94(10), pp. 1443 - 1454. https://doi.org/10.2522/ptj.20130444
Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes
Bryant, Christina, Lewis, Prudence, Bennell, Kim, Ahamed, Yasmin, Crough, Denae, Jull, Gwendolen, Kenardy, Justin, Nicholas, Michael and Keefe, Francis. (2014). Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes. Physical Therapy. 94(10), pp. 1443 - 1454. https://doi.org/10.2522/ptj.20130444
Alternating bouts of sitting and standing attenuate postprandial glucose responses
Thorp, Michael, Keefe, Francis, Bryant, Christina, Metcalf, Ben, Ahamed, Yasmin, Nicholas, Michael and Bennell, Kim. (2013). Alternating bouts of sitting and standing attenuate postprandial glucose responses. Medicine and Science in Sports and Exercise. 20(2), pp. 106 - 112. https://doi.org/10.1249/MSS.0000000000000337
A physiotherapist-delivered, combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis : A pilot study
Hunt, Michael, Keefe, Francis, Bryant, Christina, Metcalf, Ben, Ahamed, Yasmin, Nicholas, Michael and Bennell, Kim. (2013). A physiotherapist-delivered, combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis : A pilot study. The Knee. 20(2), pp. 106 - 112. https://doi.org/10.1016/j.knee.2012.07.008
A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: A randomised controlled trial protocol
Bennell, Kim, Ahamed, Yasmin, Bryant, Christina, Jull, Gwendolen, Hunt, Michael, Kenardy, Justin, Forbes, Andrew, Harris, Anthony, Nicholas, Michael, Metcalf, Ben, Egerton, Thorlene and Keefe, Francis. (2012). A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: A randomised controlled trial protocol. BMC Musculoskeletal Disorders. 13(129), pp. 1 - 17. https://doi.org/10.1186/1471-2474-13-129
Older fallers with poor working memory overestimate their postural limits
Liu-Ambrose, Teresa, Ahamed, Yasmin, Graf, Peter, Feldman, Fabio and Robinovitch, Stephen. (2008). Older fallers with poor working memory overestimate their postural limits. Archives of Physical Medicine and Rehabilitation. 89(7), pp. 1335 - 1340. https://doi.org/10.1016/j.apmr.2007.11.052
Otago home-based strength and balance retraining improves executive functioning in older fallers: A randomized controlled trial
Liu-Ambrose, Teresa, Donaldson, Meghan, Ahamed, Yasmin, Graf, Peter, Cook, Wendy, Close, Jacqueline, Lord, Stephen and Khan, Karim. (2008). Otago home-based strength and balance retraining improves executive functioning in older fallers: A randomized controlled trial. Journal of the American Geriatrics Society. 56(10), pp. 1821 - 1830. https://doi.org/10.1111/j.1532-5415.2008.01931.x
Characterising cortical density in the mid-tibia: Intra-individual variation in adolescent girls and boys
Cooper, David M.L., Ahamed, Yasmin, Macdonald, Heather M. and McKay, Heather Anne. (2008). Characterising cortical density in the mid-tibia: Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys
Cooper, David, Ahamed, Yasmin, Macdonald, Heather and McKay, Heather. (2008). Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
Otago home-based strength and balance retraining improves executive functioning in older fallers : A randomized controlled trial
Liu-Ambrose, Teresa, Donaldson, Meghan, Ahamed, Yasmin, Graf, Peter, Cook, Wendy, Close, Jacqueline, Lord, Stephen and Khan, Karim. (2008). Otago home-based strength and balance retraining improves executive functioning in older fallers : A randomized controlled trial. Journal of the American Geriatrics Society. 56(10), pp. 1821 - 1830. https://doi.org/10.1111/j.1532-5415.2008.01931.x
Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys
Cooper, David, Ahamed, Yasmin, Macdonald, Heather and McKay, Heather. (2008). Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
Older fallers with poor working memory overestimate their postural limits
Liu-Ambrose, Teresa, Ahamed, Yasmin, Graf, Peter, Feldman, Fabio and Robinovitch, Stephen. (2008). Older fallers with poor working memory overestimate their postural limits. Archives of Physical Medicine and Rehabilitation. 89(7), pp. 1335 - 1340. https://doi.org/10.1016/j.apmr.2007.11.052
School-based physical activity does not compromise children's academic performance
Ahamed, Yasmin, MacDonald, Heather, Reed, Katherine, Naylor, Patti-Jean, Liu-Ambrose, Teresa and McKay, Heather. (2007). School-based physical activity does not compromise children's academic performance. Medicine & Science in Sports & Exercise. 39(2), pp. 371 - 376. https://doi.org/10.1249/01.mss.0000241654.45500.8e
School-based physical activity does not compromise children's academic performance
Ahamed, Yasmin, MacDonald, Heather, Reed, Katherine, Naylor, Patti-Jean, Liu-Ambrose, Teresa and McKay, Heather. (2007). School-based physical activity does not compromise children's academic performance. Medicine and Science in Sports and Exercise. 39(2), pp. 371 - 376. https://doi.org/10.1249/01.mss.0000241654.45500.8e