Potential roles of n-3 PUFAs during skeletal muscle growth and regeneration

Journal article


Tachtsis, Bill, Camera, Donny and Lacham-Kaplan, Orly. (2018) Potential roles of n-3 PUFAs during skeletal muscle growth and regeneration. Nutrients. 10(3), pp. 1 - 20. https://doi.org/10.3390/nu10030309
AuthorsTachtsis, Bill, Camera, Donny and Lacham-Kaplan, Orly
Abstract

Omega-3 polyunsaturated fatty acids (n-3 PUFAs), which are commonly found in fish oil supplements, are known to possess anti-inflammatory properties and more recently alter skeletal musclefunction. In this review, we discuss novel findings related to how n-3 PUFAs modulate molecular signaling responsible for growth and hypertrophy as well as the activity of muscle stem cells. Muscle stem cells commonly known as satellite cells, are primarily responsible for driving the skeletal muscle repair process to potentially damaging stimuli, such as mechanical stress elicited by exercise contraction. To date, there is a paucity of human investigations related to the effects of n-3 PUFAs on satellite cell content and activity. Based on current in vitro investigations, this review focuses on novel mechanisms linking n-3 PUFA’s to satellite cell activity and how they may improve muscle repair. Understanding the role of n-3 PUFAs during muscle growth and regeneration in association with exercise could lead to the development of novel supplementation strategies that increase muscle mass and strength, therefore possibly reducing the burden of muscle wasting with age.

Keywordsageing; Omega-3; satellite cells; skeletal muscle
Year2018
JournalNutrients
Journal citation10 (3), pp. 1 - 20
PublisherMDPI AG
ISSN2072-6643
Digital Object Identifier (DOI)https://doi.org/10.3390/nu10030309
Scopus EID2-s2.0-85043310921
Page range1 - 20
Research GroupMary MacKillop Institute for Health Research
EditorsJ. Buckley
Permalink -

https://acuresearchbank.acu.edu.au/item/87y87/potential-roles-of-n-3-pufas-during-skeletal-muscle-growth-and-regeneration

Restricted files

Publisher's version

  • 2
    total views
  • 0
    total downloads
  • 1
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men
Smiles, William J., Churchward-Venne, Tyler A., van Loon, Luc J. C., Hawley, John A. and Camera, Donny M.. (2019) A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men. The FASEB Journal. 33(6), pp. 7009 - 7017. https://doi.org/10.1096/fj.201801917R
Augmented anabolic responses after 8-wk cycling with blood flow restriction
Conceição, Miguel Soares, Mendes, Telles, Guilherme Defante, Libardi, Cleiton Augusto, Castro, Alex, Andrade, André L. L., Brum, Patrícia Chakur, Urias, Úrsula, Kurauti, Mirian Ayumi, Costa, Boschero, Antonio Carlos, Cavaglieri, Cláudia Regina, Camera, Donny M., Chacon-Mikahil, Mara Patricia Traina, Junior, Edson Manoel Mendes and Júnior, José Maria Costa. (2019) Augmented anabolic responses after 8-wk cycling with blood flow restriction. Medicine and Science in Sports and Exercise. 51(1), pp. 84 - 93. https://doi.org/10.1249/MSS.0000000000001755
Effects of creatine and carbohydrate loading on cycling time trial performance
Tomcik, Kristyen A., Camera, Donny, Bone, Julia L. L., Ross, Meg, Jeacocke, N. A., Tachtsis, Bill, Senden, Joan M., Van Loon, Luc, Hawley, John and Burke, Louise. (2018) Effects of creatine and carbohydrate loading on cycling time trial performance. Medicine and Science in Sports and Exercise. 50(1), pp. 141 - 150. https://doi.org/10.1249/MSS.0000000000001401
Potential Roles of n-3 PUFAs during Skeletal Muscle Growth and Regeneration
Tachtsis, Bill, Camera, Donny and Lacham-Kaplan, Orly. (2018) Potential Roles of n-3 PUFAs during Skeletal Muscle Growth and Regeneration. Nutrients. 10(3), p. 309. https://doi.org/10.3390/nu10030309
Anabolic heterogeneity following resistance training: A role for Circadian rhythm?
Camera, Donny M.. (2018) Anabolic heterogeneity following resistance training: A role for Circadian rhythm? Frontiers in Physiology. 9, pp. 1 - 13. https://doi.org/10.3389/fphys.2018.00569
The guardian of the genome p53 regulates exercise-induced mitochondrial plasticity beyond organelle biogenesis
Smiles, William and Camera, Donny. (2018) The guardian of the genome p53 regulates exercise-induced mitochondrial plasticity beyond organelle biogenesis. Acta Physiologica. 222(3), pp. 1 - 13. https://doi.org/10.1111/apha.13004
Protein availability and satellite cell dynamics in skeletal muscle
Shamim, Baubak, Hawley, John and Camera, Donny. (2018) Protein availability and satellite cell dynamics in skeletal muscle. Sports Medicine. 48(6), pp. 1329 - 1343. https://doi.org/10.1007/s40279-018-0883-7
Where do satellite cells orbit? An endomysium space odyssey
Shamim, Baubak, Conceicao, Miguel, Callahan, Marcus J. and Camera, Donny. (2018) Where do satellite cells orbit? An endomysium space odyssey. The Journal of Physiology. 596(10), pp. 1791 - 1792. https://doi.org/10.1113/JP276024
Muscle fiber hypertrophy and myonuclei addition: a systematic review and meta-analysis
Conceição, Miguel S., Vechin, Felipe C., Lixandrão, Manoel, Damas, Felipe, Libardi, Cleiton A., Tricoli, Valmor, Roschel, Hamilton, Camera, Donny and Ugrinowitsch, Carlos. (2018) Muscle fiber hypertrophy and myonuclei addition: a systematic review and meta-analysis. Medicine and Science in Sports and Exercise. 50(7), pp. 1385 - 1393. https://doi.org/10.1249/MSS.0000000000001593
Adaptations to concurrent training in combination with high protein availability: A comparative trial in healthy, recreationally active men
Shamim, Baubak, Devlin, Brooke L., Timmins, Ryan G., Tofari, Paul, Dow, Connor Lee, Coffey, Vernon G., Hawley, John A. and Camera, Donny M.. (2018) Adaptations to concurrent training in combination with high protein availability: A comparative trial in healthy, recreationally active men. Sports Medicine. 48(12), pp. 2869 - 2883. https://doi.org/10.1007/s40279-018-0999-9
Fenugreek increases insulin-stimulated creatine content in l6C11 muscle myotubes
Tomcik, Kristyen, Smiles, William, Camera, Donny, Hugel, Helmut M., Hawley, John and Watts, Rani. (2017) Fenugreek increases insulin-stimulated creatine content in l6C11 muscle myotubes. European Journal of Nutrition. 56(3), pp. 973 - 979. https://doi.org/10.1007/s00394-015-1145-1
Acute low-intensity cycling with blood-flow restriction has no effect on metabolic signaling in human skeletal muscle compared to traditional exercise
Smiles, William, Conceição, Miguel S., Telles, Guilherme D., Chacon-Mikahil, Mara P.T., Cavaglieri, Cláudia R., Vechin, Felipe C., Libardi, Cleiton A., Hawley, John and Camera, Donny. (2017) Acute low-intensity cycling with blood-flow restriction has no effect on metabolic signaling in human skeletal muscle compared to traditional exercise. European Journal of Applied Physiology. 117(2), pp. 345 - 358. https://doi.org/10.1007/s00421-016-3530-8
Dynamic proteome profiling of individual proteins in human skeletal muscle after a high-fat diet and resistance exercise
Camera, Donny, Burniston, Jatin G., Pogson, Mark A., Smiles, William and Hawley, John. (2017) Dynamic proteome profiling of individual proteins in human skeletal muscle after a high-fat diet and resistance exercise. The FASEB Journal. 31(12), pp. 5478 - 5494. https://doi.org/10.1096/fj.201700531R
Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans
Laker, R. C., Garde, C., Camera, Donny, Smiles, William, Zierath, J. R., Hawley, John and Barrès, R.. (2017) Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans. Scientific Reports. 7(1), pp. 1 - 12. https://doi.org/10.1038/s41598-017-15420-7
Expression of microRNAs and target proteins in skeletal muscle of rats selectively bred for high and low running capacity
Pinto, Samuel K., Lamon, Séverine, Stephenson, Erin J., Kalanon, M., Mikovic, Jasmine, Koch, L G., Britton, S. L., Hawley, John and Camera, Donny. (2017) Expression of microRNAs and target proteins in skeletal muscle of rats selectively bred for high and low running capacity. American Journal of Physiology - Endocrinology and Metabolism. 313(3), pp. 335 - 343. https://doi.org/10.1152/ajpendo.00043.2017
Acute endurance exercise induces nuclear p53 abundance in human skeletal muscle
Tachtsis, Bill, Smiles, William, Lane, Steven C., Hawley, John Alan and Camera, Donny Michael. (2016) Acute endurance exercise induces nuclear p53 abundance in human skeletal muscle. Frontiers in Physiology. 7(144), pp. 1 - 10. https://doi.org/10.3389/fphys.2016.00144
Circulating microRNA responses between 'high' and 'low' responders to a 16-wk diet and exercise weight loss intervention
Parr, Evelyn B., Camera, Donny M., Burke, Louise M., Phillips, Stuart M., Coffey, Vernon G. and Hawley, John Alan. (2016) Circulating microRNA responses between 'high' and 'low' responders to a 16-wk diet and exercise weight loss intervention. PLoS ONE. 11(4), pp. 1 - 14. https://doi.org/10.1371/journal.pone.0152545
Commentaries on Viewpoint: The rigorous study of exercise adaptations: Why mRNA might not be enough
Camera, Donny and Hawley, John. (2016) Commentaries on Viewpoint: The rigorous study of exercise adaptations: Why mRNA might not be enough. Journal of Applied Physiology. 121(2), pp. 598 - 598. https://doi.org/10.1152/japplphysiol.00509.2016
Exercise-induced skeletal muscle signaling pathways and human athletic performance
Camera, Donny Michael, Smiles, William J. and Hawley, John Alan. (2016) Exercise-induced skeletal muscle signaling pathways and human athletic performance. Free Radical Biology & Medicine. 98, pp. 131 - 143. https://doi.org/10.1016/j.freeradbiomed.2016.02.007
Effects of skeletal muscle energy availability on protein turnover responses to exercise
Smiles, William J., Hawley, John Alan and Camera, Donny Michael. (2016) Effects of skeletal muscle energy availability on protein turnover responses to exercise. Journal of Experimental Biology. 219(Pt 2), pp. 214 - 225. https://doi.org/10.1242/jeb.125104
Protein coingestion with alcohol following strenuous exercise attenuates alcohol-induced intramyocellular apoptosis and inhibition of autophagy
Smiles, William J., Parr, Evelyn B., Coffey, Vernon G., Lacham-Kaplan, Orly, Hawley, John Alan and Camera, Donny Michael. (2016) Protein coingestion with alcohol following strenuous exercise attenuates alcohol-induced intramyocellular apoptosis and inhibition of autophagy. American Journal of Physiology - Endocrinology and Metabolism. 311(5), pp. E836 - E849. https://doi.org/10.1152/ajpendo.00303.2016
Attenuated PGC-1a isoforms following endurance exercise with blood flow restriction
Conceição, Miguel Soares, Chacon-Mikahil, Mara Patricia Traina, Telles, Guilherme Defante, Libardi, Cleiton Augusto, Junior, Edson Manoel Mendes, Vechin, Felipe Cassaro, Lugani de Andrade, André Luis, Gáspari, Arthur Fernandes, Brum, Patricia Chakur, Cavaglieri, Cláudia Regina, Serag, Sara, Spiegelman, Bruce M., Hawley, John Alan and Camera, Donny Michael. (2016) Attenuated PGC-1a isoforms following endurance exercise with blood flow restriction. Medicine and Science in Sports and Exercise. 16(4809), pp. 1699 - 1707. https://doi.org/10.1249/MSS.0000000000000970
Selective modulation of microRNA expression with protein ingestion following concurrent resistance and endurance exercise in human skeletal muscle
Camera, Donny Michael, Ong, Jun N., Coffey, Vernon Glenn and Hawley, John Alan. (2016) Selective modulation of microRNA expression with protein ingestion following concurrent resistance and endurance exercise in human skeletal muscle. Frontiers in Physiology. 7(Mar), pp. 1 - 8. https://doi.org/10.3389/fphys.2016.00087
Need for measures of satellite cell activation along with muscle protein synthesis?
Camera, Donny and Hawley, John. (2015) Need for measures of satellite cell activation along with muscle protein synthesis? Journal of Applied Physiology. 118(4), pp. 500 - 500. https://doi.org/10.1152/japplphysiol.00609.2014.
Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training
Parr, Evelyn, Camera, Donny, Areta, José, Burke, Louise, Phillips, Stuart, Hawley, John A. and Coffey, Vernon. (2014) Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training. PLoS ONE. 9(2), pp. 1 - 9. https://doi.org/10.1371/journal.pone.0088384
Beyond muscle hypertrophy: Why dietary protein is important for endurance athletes
Moore, Daniel, Camera, Donny, Areta, José and Hawley, John A.. (2014) Beyond muscle hypertrophy: Why dietary protein is important for endurance athletes. Applied Physiology, Nutrition and Metabolism. 39(9), pp. 987 - 997. https://doi.org/10.1139/apnm-2013-0591
Reduced resting skeletal muscle protein synthesis is reduced by resistance exercise and protein ingestion following short-term energy deficit
Areta, José, Burke, Louise, Camera, Donny, West, Daniel, Crawshay, Siobhan, Moore, Daniel, Stellingwerff, Trent, Phillips, Stuart, Hawley, John A. and Coffey, Vernon. (2014) Reduced resting skeletal muscle protein synthesis is reduced by resistance exercise and protein ingestion following short-term energy deficit. American Journal of Physiology - Endocrinology and Metabolism. 306(8), pp. E989 - E997. https://doi.org/10.1152/ajpendo.00590.2013
Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis
Rao, Rajesh, Long, Jonathan, White, James, Svensson, Katrin, Lou, Jesse, Lokurkar, Isha, Jedrychowski, Mark, Ruas, Jorge, Wrann, Christiane, Lo, James, Camera, Donny, Lachey, Jenn, Gygi, Steven, Seehra, Jasbir, Hawley, John and Spiegelman, Bruce. (2014) Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell. 157(6), pp. 1279 - 1291. https://doi.org/10.1016/j.cell.2014.03.065
Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis
Rao, Rajesh, Long, Jonathan Z., White, James P., Svensson, Katrin J., Lou, Jesse, Lokurkar, Isha, Jedrychowski, Mark P., Ruas, Jorge L., Wrann, Christine D., Camera, Donny, Lachey, Jenn, Gygi, Steven, Seehra, Jasbir, Hawley, John and Spiegelman, Bruce M.. (2014) Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis. Cell. 157(6), pp. 1279 - 1291. https://doi.org/10.1016/j.cell.2014.03.065
ERK1/2 in the brain mediates the effects of central resistin on reducing thermogenesis in brown adipose tissue
Kosari, Samin, Camera, Donny Michael, Hawley, John Alan, Stebbing, Martin and Badoer, Emilio. (2013) ERK1/2 in the brain mediates the effects of central resistin on reducing thermogenesis in brown adipose tissue. International Journal of Physiology, Pathophysiology and Pharmacology. 5(3), pp. 184 - 189.
Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis
Areta, José, Burke, Louise, Ross, M, Camera, Donny, West, D, Broad, E, Jeacocke, N, Moore, Daniel, Stellingwerff, T and Phillips, S. (2013) Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. The Journal of Physiology. https://doi.org/10.1113/jphysiol.2012.244897
Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet
Stephenson, E, Camera, Donny, Jenkins, T, Kosari, S, Lee, Joohyung, Hawley, John and Stepto, N. (2012) Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet. American Journal of Physiology - Endocrinology and Metabolism. 302(12), pp. E1541 - E1549. https://doi.org/10.1152/ajpendo.00590.2011
Sex-based comparisons of myofibrillar protein synthesis after resistance exercise in the fed state
West, D, Burd, N, Churchward-Venne, T, Camera, Donny, Mitchell, Cameron, Baker, S, Hawley, John, Coffey, Vernon and Phillips, S. (2012) Sex-based comparisons of myofibrillar protein synthesis after resistance exercise in the fed state. Journal of Applied Physiology. 112(11), pp. 1805 - 1813. https://doi.org/10.1152/japplphysiol.00170.2012
Low muscle glycogen concentration does not suppress the anabolic response to resistance exercise
Camera, Donny, West, D, Burd, N, Phillips, S, Garnham, A, Hawley, John and Coffey, Vernon. (2012) Low muscle glycogen concentration does not suppress the anabolic response to resistance exercise. Journal of Applied Physiology. 113(2), pp. 206 - 214. https://doi.org/10.1152/japplphysiol.00395.2012
No role for early IGF-1 signalling in stimulating acute 'muscle building' responses
Burd, Nicholas A., West, D. W., Camera, Donny and Breen, L.. (2011) No role for early IGF-1 signalling in stimulating acute 'muscle building' responses. The Journal of Physiology. https://doi.org/10.1113/jphysiol.2011.207332
Early time course of akt phosphorylation after endurance and resistance exercise
Camera, Donny, Edge, J, Short, M, Hawley, John and Coffey, Vernon. (2010) Early time course of akt phosphorylation after endurance and resistance exercise. Medicine and Science in Sports and Exercise. 42(10), pp. 1843 - 1852. https://doi.org/10.1249/MSS.0b013e3181d964e4
Short-term endurance training does not alter the oxidative capacity of human subcutaneous adipose tissue
Camera, Donny, Anderson, Malcolm, Hawley, John and Carey, A. (2010) Short-term endurance training does not alter the oxidative capacity of human subcutaneous adipose tissue. European Journal of Applied Physiology. 109(2), pp. 307 - 316. https://doi.org/10.1007/s00421-010-1356-3
Reprogramming of DNA replication timing
Shufaro, Yoel, Lacham-Kaplan, Orly, Tzuberi, Ben Zion, Mclaughlin, John, Trounson, Alan, Cedar, Howard and Reubinoff, Benjamin E.. (2010) Reprogramming of DNA replication timing. Stem Cells. 28(3), pp. 443 - 449. https://doi.org/10.1002/stem.303
Differentiation of germ cells and gametes from stem cells
Marques-Mari, A. I., Lacham-Kaplan, Orly, Medrano, J. V., Pellicer, A. and Simón, C.. (2009) Differentiation of germ cells and gametes from stem cells. Human Reproduction Update. 15(3), pp. 379 - 390. https://doi.org/10.1093/humupd/dmp001
Gene expression profiling of human oocytes following in vivo or in vitro maturation
Jones, Gayle M., Cram, David S., Song, Bi, Magli, M. Cristina, Gianaroli, Luca, Lacham-Kaplan, Orly, Findlay, Jock K., Jenkin, Graham and Trounson, Alan. (2008) Gene expression profiling of human oocytes following in vivo or in vitro maturation. Human Reproduction. 23(5), pp. 1138 - 1144. https://doi.org/10.1093/humrep/den085
Density gradients for the isolation of germ cells from embryoid bodies
Saiti, Deshira and Lacham-Kaplan, Orly. (2008) Density gradients for the isolation of germ cells from embryoid bodies. Reproductive Biomedicine Online. 16(5), pp. 730 - 740. https://doi.org/10.1016/S1472-6483(10)60489-0
Reduced developmental competence of immature, in-vitro matured and postovulatory aged mouse oocytes following IVF and ICSI
Lacham-Kaplan, Orly and Trounson, Alan. (2008) Reduced developmental competence of immature, in-vitro matured and postovulatory aged mouse oocytes following IVF and ICSI. Reproductive Biology and Endocrinology. 6(1). https://doi.org/10.1186/1477-7827-6-58
Shedding new light on the molecular architecture of oocytes using a combination of synchrotron fourier transform-infrared and raman spectroscopic mapping
Wood, Bayden R., Chernenko, Tatyana, Matthäus, Christian, Diem, Max, Chong, Connie, Bernhard, Uditha, Jene, Cassandra, Brandli, Alice A., McNaughton, Don, Tobin, Mark J., Trounson, Alan and Lacham-Kaplan, Orly. (2008) Shedding new light on the molecular architecture of oocytes using a combination of synchrotron fourier transform-infrared and raman spectroscopic mapping. Analytical Chemistry. 80(23), pp. 9065 - 9072. https://doi.org/10.1021/ac8015483
In vitro maturation and intracytoplasmic sperm injection of oocytes collected from hormonally stimulated common wombats, Vombatus ursinus
West, M., Lacham-Kaplan, Orly, Cleary, M., Galloway, D., Shaw, J., Trounson, Alan and Paris, M. C. J.. (2007) In vitro maturation and intracytoplasmic sperm injection of oocytes collected from hormonally stimulated common wombats, Vombatus ursinus. Animal Reproduction Science. 98(43924), pp. 311 - 321. https://doi.org/10.1016/j.anireprosci.2006.03.005
Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating
Wilson, Trevor J., Lacham-Kaplan, Orly, Gould, Jodee, Holloway, Andrew, Bertoncello, Ivan, Hertzog, Paul J. and Trounson, Alan. (2007) Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating. Molecular Reproduction and Development. 74(4), pp. 512 - 519. https://doi.org/10.1002/mrd.20644
The employment of strontium to activate mouse oocytes: Effects on spermatid-injection outcome
Loren, Jean and Lacham-Kaplan, Orly. (2006) The employment of strontium to activate mouse oocytes: Effects on spermatid-injection outcome. Reproduction. 131(2), pp. 259 - 267. https://doi.org/10.1530/rep.1.00894
Testicular cell conditioned medium supports differentiation of embryonic stem cells into ovarian structures containing oocytes
Lacham-Kaplan, Orly, Chy, Hun and Trounson, Alan. (2006) Testicular cell conditioned medium supports differentiation of embryonic stem cells into ovarian structures containing oocytes. Stem Cells. 24(2), pp. 266 - 273. https://doi.org/10.1634/stemcells.2005-0204
In vivo and in vitro differentiation of male germ cells in the mouse
Lacham-Kaplan, Orly. (2004) In vivo and in vitro differentiation of male germ cells in the mouse. Reproduction. 128(2), pp. 147 - 152. https://doi.org/10.1530/rep.1.00220
Oocyte Activation after Intracytoplasmic Injection with Sperm Frozen Without Cryoprotectants Results in Live Offspring from Inbred and Hybrid Mouse Strains
Lacham-Kaplan, Orly, Shaw, J., Sanchez-Partida, L. Gabriel and Trounson, Alan. (2003) Oocyte Activation after Intracytoplasmic Injection with Sperm Frozen Without Cryoprotectants Results in Live Offspring from Inbred and Hybrid Mouse Strains. Biology of Reproduction. 69(5), pp. 1683 - 1689. https://doi.org/10.1095/biolreprod.103.018184
Effects of electrical stimulation and seminal plasma on the motility of mouse sperm
Tecirlio¿lu, R. T., Lacham-Kaplan, Orly and Trounson, Alan. (2002) Effects of electrical stimulation and seminal plasma on the motility of mouse sperm. Reproduction Fertility and Development. 14(44050), pp. 471 - 478. https://doi.org/10.1071/RD02050
Cell synchronization for the purposes of nuclear transfer in the bovine
Korfiatis, Natasha, Trounson, Alan and Lacham-Kaplan, Orly. (2001) Cell synchronization for the purposes of nuclear transfer in the bovine. Cellular Reprogramming. 3(3), pp. 125 - 138. https://doi.org/10.1089/153623001753205089
Fertilization of mouse oocytes using somatic cells as male germ cells
Lacham-Kaplan, Orly, Daniels, Rob and Trounson, Alan. (2001) Fertilization of mouse oocytes using somatic cells as male germ cells. Reproductive Biomedicine Online. 3(3), pp. 205 - 211. https://doi.org/10.1016/S1472-6483(10)62037-8
Characterization of the fertility of male aromatase knockout mice
Robertson, K. M., Simpson, Evan, Lacham-Kaplan, Orly and Jones, Margaret. (2001) Characterization of the fertility of male aromatase knockout mice. Journal of Andrology. 22(5), pp. 825 - 830.
Nuclear transfer of adult and genetically modified fetal cells of the rat
Hayes, Eric, Galea, Sandra, Verkuylen, Amanda, Pera, Martin, Morrison, John, Lacham-Kaplan, Orly and Trounson, Alan. (2001) Nuclear transfer of adult and genetically modified fetal cells of the rat. Physiological Genomics. 5(4), pp. 193 - 203.
Pregnancies produced from fertile and infertile stallions by intracytoplasmic sperm injection (ICSI) of single frozen-thawed spermatozoa into in vivo matured mare oocytes.
McKinnon, A. O., Lacham-Kaplan, Orly and Trounson, Alan. (2000) Pregnancies produced from fertile and infertile stallions by intracytoplasmic sperm injection (ICSI) of single frozen-thawed spermatozoa into in vivo matured mare oocytes. Reproduction: Supplement.
Developmental competence of nuclear transfer cow oocytes after direct injection of fetal fibroblast nuclei
Lacham-Kaplan, Orly, Diamente, Maria, Pushett, David, Lewis, Ian and Trounson, Alan. (2000) Developmental competence of nuclear transfer cow oocytes after direct injection of fetal fibroblast nuclei. Cloning. 2(2), pp. 55 - 62. https://doi.org/10.1089/152045500436078
Intracytoplasmic sperm injection, zona drilling and zona removal of the human oocyte and embryo
Okuma, Y., Lacham-Kaplan, Orly and Trounson, Alan. (1998) Intracytoplasmic sperm injection, zona drilling and zona removal of the human oocyte and embryo. Zygote. 6(Supplement 1), pp. 51 - 51.
Is the acrosome reaction a prerequisite for sperm incorporation after intra-cytoplasmic sperm injection (ICSI)?
Sathananthan, A. H., Szell, A., Ng, S. C., Kausche, A., Lacham-Kaplan, Orly and Trounson, Alan. (1997) Is the acrosome reaction a prerequisite for sperm incorporation after intra-cytoplasmic sperm injection (ICSI)? Reproduction Fertility and Development. 9(7), pp. 703 - 709. https://doi.org/10.1071/R97028
Fertilization and embryonic developmental capacity of epididymal and testicular sperm and immature spermatids and spermatocytes
Lacham-Kaplan, Orly and Trounson, Alan. (1997) Fertilization and embryonic developmental capacity of epididymal and testicular sperm and immature spermatids and spermatocytes. Reproductive Medicine Review. 6(1), pp. 55 - 68.
Blastocyst development and birth after in-vitro maturation of human primary oocytes, intracytoplasmic sperm injection and assisted hatching
Barnes, Frank L., Crombie, Amanda, Gardner, David K., Kausche, A., Lacham-Kaplan, Orly, Suikkari, Anne Maria, Tiglias, Jennifer, Wood, Carl and Trounson, Alan. (1995) Blastocyst development and birth after in-vitro maturation of human primary oocytes, intracytoplasmic sperm injection and assisted hatching. Human Reproduction. 10(12), pp. 3243 - 3247. https://doi.org/10.1093/oxfordjournals.humrep.a135896
Intracytoplasmic sperm injection in mice: Increased fertilization and development to term after induction of the acrosome reaction
Lacham-Kaplan, Orly and Trounson, Alan. (1995) Intracytoplasmic sperm injection in mice: Increased fertilization and development to term after induction of the acrosome reaction. Human Reproduction. 10(10), pp. 2642 - 2649. https://doi.org/10.1093/oxfordjournals.humrep.a135760
Embryo development capacity of oocytes fertilized by immature sperm and sperm treated with motility stimulants
Lacham-Kaplan, Orly and Trounson, Alan. (1994) Embryo development capacity of oocytes fertilized by immature sperm and sperm treated with motility stimulants. Reproduction Fertility and Development. 6(1), pp. 113 - 116. https://doi.org/10.1071/RD9940113
Microinjection: Choice of embryo transfer technique
McLachlan, Robert I., Fuscaldo, Giuliana, Calderon, Ilan, Lacham-Kaplan, Orly, Poulos, Christine, Rho, Hwan, Trounson, Alan and Wood, Carl. (1994) Microinjection: Choice of embryo transfer technique. Reproduction Fertility and Development. 6(1), pp. 57 - 61. https://doi.org/10.1071/RD9940057
The effects of the sperm motility activators 2-deoxyadenosine and pentoxifylline used for sperm micro-injection on mouse and human embryo development
Lacham-Kaplan, Orly and Trounson, Alan. (1993) The effects of the sperm motility activators 2-deoxyadenosine and pentoxifylline used for sperm micro-injection on mouse and human embryo development. Human Reproduction. 8(6), pp. 945 - 952. https://doi.org/10.1093/oxfordjournals.humrep.a138172
Subzonal sperm microinjection in cases of severe male factor infertility and repeated in vitro fertilization failure
Sakkas, D., Lacham-Kaplan, Orly, Gianaroli, Luca and Trounson, Alan. (1992) Subzonal sperm microinjection in cases of severe male factor infertility and repeated in vitro fertilization failure. Fertility and Sterility. 57(6), pp. 1279 - 1288.
Fertilizing capacity of epididymal and testicular spermatozoa microinjected under the zona pellucida of the mouse oocyte
Lacham-Kaplan, Orly and Trounson, Alan. (1991) Fertilizing capacity of epididymal and testicular spermatozoa microinjected under the zona pellucida of the mouse oocyte. Molecular Reproduction and Development. 29(1), pp. 85 - 93. https://doi.org/10.1002/mrd.1080290113
Chromosomal analysis of human oocytes fertilized by microinjection of spermatozoa into the perivitelline space
Kola, Ismail, Lacham-Kaplan, Orly, Jansen, Robert P. S., Turner, Marie and Trounson, Alan. (1990) Chromosomal analysis of human oocytes fertilized by microinjection of spermatozoa into the perivitelline space. Human Reproduction. 5(5), pp. 575 - 577. https://doi.org/10.1093/oxfordjournals.humrep.a137147
Fertilization and development of mouse eggs injected under the zona pellucida with single spermatozoa treated to induce the acrosome reaction
Lacham-Kaplan, Orly, Trounson, Alan, Holden, Carol, Mann, Jeff and Sathananthan, Henry. (1989) Fertilization and development of mouse eggs injected under the zona pellucida with single spermatozoa treated to induce the acrosome reaction. Gamete Research. 23(2), pp. 233 - 243. https://doi.org/10.1002/mrd.1120230210
Fertilization of mouse and human eggs by microinjection of single spermatozoa under the zona pellucida.
Trounson, Alan, Peura, A. and Lacham-Kaplan, Orly. (1989) Fertilization of mouse and human eggs by microinjection of single spermatozoa under the zona pellucida. Reproduction: Supplement. 38, pp. 145 - 152.