Mortality and Clostridium difficile infection : a review
Journal article
Mitchell, Brett G. and Gardner, Anne. (2012). Mortality and Clostridium difficile infection : a review. Antimicrobial Resistance and Infection Control. 1(20). https://doi.org/10.1186/2047-2994-1-20
Authors | Mitchell, Brett G. and Gardner, Anne |
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Abstract | Background: Clostridium difficile infection (CDI) is a common cause of diarrhoea in hospitalised patients. Around the world, the incidence and severity of CDI appears to be increasing, particularly in the northern hemisphere. The purpose of this integrative review was to investigate and describe mortality in hospitalised patients with CDI. Methods: A search of the literature between 1 January 2005 and 30 April 2011 focusing on mortality and CDI in hospitalised patients was conducted using electronic databases. Papers were reviewed and analysed individually and themes were combined using integrative methods. Results: All cause mortality at 30 days varied from 9% to 38%. Three studies report attributable mortality at 30 days, varying from 5.7% to 6.9%. In hospital mortality ranged from 8% to 37.2% Conclusion: All cause 30 day mortality appeared to be high, with 15 studies indicating a mortality of 15% or greater. Findings support the notion that CDI is a serious infection and measures to prevent and control CDI are needed. Future studies investigating the mortality of CDI in settings outside of Europe and North America are needed. Similarly, future studies should include data on patient co-morbidities. |
Keywords | Clostridium difficile infection; Clostridium difficile associated diarrhoea ; Mortality ; Death |
Year | 2012 |
Journal | Antimicrobial Resistance and Infection Control |
Journal citation | 1 (20) |
ISSN | 2047-2994 |
Digital Object Identifier (DOI) | https://doi.org/10.1186/2047-2994-1-20 |
Web address (URL) | https://aricjournal.biomedcentral.com/articles/10.1186/2047-2994-1-20 |
Open access | Open access |
Page range | 1-6 |
Research Group | School of Nursing, Midwifery and Paramedicine |
Publisher's version | |
Output status | Published |
Publication dates | |
Online | 30 May 2012 |
Additional information | © 2012 Mitchell and Gardner; licensee BioMed Central Ltd |
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
https://acuresearchbank.acu.edu.au/item/880v9/mortality-and-clostridium-difficile-infection-a-review
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