Gross morphological brain changes with chronic, heavy cannabis use
Journal article
Lorenzetti, Valentina, Solowij, Nadia, Whittle, Sarah, Fornito, Alex, Lubman, Dan I., Pantelis, Christos and Yücel, Murat. (2015). Gross morphological brain changes with chronic, heavy cannabis use. British Journal of Psychiatry. 206(1), pp. 77 - 78. https://doi.org/10.1192/bjp.bp.114.151407
Authors | Lorenzetti, Valentina, Solowij, Nadia, Whittle, Sarah, Fornito, Alex, Lubman, Dan I., Pantelis, Christos and Yücel, Murat |
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Abstract | We investigated the morphology of multiple brain regions in a rare sample of 15 very heavy cannabis users with minimal psychiatric comorbidity or significant exposure to other substances (compared with 15 age- and IQ-matched non-cannabis-using controls) using manual techniques. Heavy cannabis users demonstrated smaller hippocampus and amygdala volumes, but no alterations of the orbitofrontal and anterior- and paracingulate cortices, or the pituitary gland. These findings indicate that chronic cannabis use has a selective and detrimental impact on the morphology of the mediotemporal lobe. |
Year | 2015 |
Journal | British Journal of Psychiatry |
Journal citation | 206 (1), pp. 77 - 78 |
Publisher | Royal College of Psychiatrists |
ISSN | 0007-1250 |
Digital Object Identifier (DOI) | https://doi.org/10.1192/bjp.bp.114.151407 |
Scopus EID | 2-s2.0-84920448489 |
Page range | 77 - 78 |
Publisher's version | File Access Level Controlled |
Grant ID | ARC/FT110100752 |
ARC/FT130100589 | |
Place of publication | United Kingdom |
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https://acuresearchbank.acu.edu.au/item/881q4/gross-morphological-brain-changes-with-chronic-heavy-cannabis-use
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