Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study : Analysis of 36-month observational data

Journal article


Tabrizi, Sarah, Scahill, Rachael, Owen, Gail, Durr, Alexandra, Leavitt, Blair, Roos, Raymund, Borowsky, Beth, Landwehrmeyer, Bernhard, Frost, Chris, Johnson, Hans, Craufurd, David, Reilmann, Ralf, Stout, Julie and Langbehn, Douglas. (2013). Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study : Analysis of 36-month observational data. Lancet Neurology. 12(7), pp. 637 - 649. https://doi.org/10.1016/S1474-4422(13)70088-7
AuthorsTabrizi, Sarah, Scahill, Rachael, Owen, Gail, Durr, Alexandra, Leavitt, Blair, Roos, Raymund, Borowsky, Beth, Landwehrmeyer, Bernhard, Frost, Chris, Johnson, Hans, Craufurd, David, Reilmann, Ralf, Stout, Julie and Langbehn, Douglas
Abstract

Background: TRACK-HD is a multinational prospective observational study of Huntington's disease (HD) that examines clinical and biological findings of disease progression in individuals with premanifest HD (preHD) and early-stage HD. We aimed to describe phenotypic changes in these participants over 36 months and identify baseline predictors of progression.

Year2013
JournalLancet Neurology
Journal citation12 (7), pp. 637 - 649
ISSN1474-4422
Digital Object Identifier (DOI)https://doi.org/10.1016/S1474-4422(13)70088-7
Page range637 - 649
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