Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients

Journal article

Lu, Jun, Chan, Kai, Gamble, Gregory D., Poppitt, S D., Othman, Asma A. and Cooper, G. J. S.. (2007). Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients. Drug Metabolism and Disposition. 35(2), pp. 221 - 227. https://doi.org/10.1124/dmd.106.012922

Authors	Lu, Jun, Chan, Kai, Gamble, Gregory D., Poppitt, S D., Othman, Asma A. and Cooper, G. J. S.
Year	2007
Journal	Drug Metabolism and Disposition
Journal citation	35 (2), pp. 221 - 227
Publisher	American Society for Pharmacology and Experimental Therapeutics
ISSN	0090-9556
Digital Object Identifier (DOI)	https://doi.org/10.1124/dmd.106.012922
Page range	221 - 227
Place of publication	United States of America

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Poppitt, S. D., Keogh, Geraldine F., Lithander, Fiona E., Chan, Kai, Wang, Yu, Mulvey, Tom B., McArdle, Brian H. and Cooper, G J. S.. (2008). Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition. 24(4), pp. 322 - 329. https://doi.org/10.1016/j.nut.2007.12.012

A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes

Gong, D., Lu, J., Chen, X., Reddy, S., Crossman, D. J., Glyn-Jones, S., Choong, Y.-S., Kennedy, J., Barry, B., Zhang, S., Chan, Y.-K., Ruggiero, K., Phillips, A. R. J. and Cooper, G. J. S.. (2008). A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes. Diabetologia. 51(9), pp. 1741-1751. https://doi.org/10.1007/s00125-008-1088-7

Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS)

Lu, Jun, Chan, Kai, Poppitt, S. D. and Cooper, G J. S.. (2007). Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS). Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 859(1), pp. 62 - 68. https://doi.org/10.1016/j.jchromb.2007.09.001

Effect of high-fat meals and fatty acid saturation on postprandial levels of the hormones ghrelin and leptin in healthy men

Poppitt, S. D., Leahy, F. E., Keogh, G. F., Wang, Y, Mulvey, T B., Stojkovic, M, Chan, Kai, Choong, Y S., McArdle, B H. and Cooper, G. J. S.. (2006). Effect of high-fat meals and fatty acid saturation on postprandial levels of the hormones ghrelin and leptin in healthy men. European Journal of Clinical Nutrition. 60(1), pp. 77 - 84. https://doi.org/10.1038/sj.ejcn.1602270

Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats

Gong, Deming, Lu, Jun, Chen, Xiuyin, Choong, Soon Y., Zhang, Shaoping, Chan, Kai, Glyn-Jones, Sarah, Gamble, Gregory D., Phillips, Anthony R. J. and Cooper, Garth J. S.. (2006). Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats. Molecular Pharmacology. 70(6), pp. 2045 - 2051. https://doi.org/10.1124/mol.106.028605

Demonstratuon of hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation

Cooper, G. J. S., Chan, Kai, Dissanayake, Ajith M., Leahy, Fiona E., Keogh, Geraldine F., Frampton, Chris M., Gamble, Gregory D., Brunton, Dianne H., Baker, John R. and Poppitt, S D.. (2005). Demonstratuon of hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation. Diabetes. 54(5), pp. 1468 - 1476.

Regeneration of the heart in diabetes by selective copper chelation

Cooper, G. J. S., Phillips, Anthony R. J., Choong, Soon Y., Leonard, Bridget L., Crossman, David J., Brunton, Dianne H., Saafi, Etuate L., Dissanayake, Ajith M., Cowan, Brett R., Young, Alistair A., Occleshaw, Christopher J., Chan, Kai, Leahy, Fiona E., Keogh, Geraldine F., Gamble, Gregory D., Allen, Grant R., Pope, Adele J., Boyd, Peter D. W., Poppitt, S D., ... Baker, John R.. (2004). Regeneration of the heart in diabetes by selective copper chelation. Diabetes. 53(9), pp. 2501 - 2508.