Effect of moderate to vigorous physical activity on all-cause mortality in middle-aged and older Australians

Journal article


Gebel, Klaus, Ding, Ding, Chey, Tien, Stamatakis, Emmanuel, Brown, Wendy and Bauman, Adrian. (2015). Effect of moderate to vigorous physical activity on all-cause mortality in middle-aged and older Australians. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2015.0541
AuthorsGebel, Klaus, Ding, Ding, Chey, Tien, Stamatakis, Emmanuel, Brown, Wendy and Bauman, Adrian
Abstract

Importance Few studies have examined how different proportions of moderate and vigorous physical activity affect health outcomes. Objective To examine whether the proportion of total moderate to vigorous activity (MVPA) that is achieved through vigorous activity is associated with all-cause mortality independently of the total amount of MVPA. Design, Setting, and Participants We performed a prospective cohort study with activity data linked to all-cause mortality data from February 1, 2006, through June 15, 2014, in 204 542 adults aged 45 through 75 years from the 45 and Up population-based cohort study from New South Wales, Australia (mean [SD] follow-up, 6.52 [1.23] years). Associations between different contributions of vigorous activity to total MVPA and mortality were examined using Cox proportional hazards models, adjusted for total MVPA and sociodemographic and health covariates. Exposures Different proportions of total MVPA as vigorous activity. Physical activity was measured with the Active Australia Survey. Main Outcomes and Measures All-cause mortality during the follow-up period. Results During 1 444 927 person-years of follow-up, 7435 deaths were registered. Compared with those who reported no MVPA (crude death rate, 8.34%), the adjusted hazard ratios for all-cause mortality were 0.66 (95% CI, 0.61-0.71; crude death rate, 4.81%), 0.53 (95% CI, 0.48-0.57; crude death rate, 3.17%), and 0.46 (95% CI, 0.43-0.49; crude death rate, 2.64%) for reporting 10 through 149, 150 through 299, and 300 min/wk or more of activity, respectively. Among those who reported any MVPA, the proportion of vigorous activity revealed an inverse dose-response relationship with all-cause mortality: compared with those reporting no vigorous activity (crude death rate, 3.84%) the fully adjusted hazard ratio was 0.91 (95% CI, 0.84-0.98; crude death rate, 2.35%) in those who reported some vigorous activity (but < 30% of total activity) and 0.87 (95% CI, 0.81-0.93; crude death rate, 2.08%) among those who reported 30% or more of activity as vigorous. These associations were consistent in men and women, across categories of body mass index and volume of MVPA, and in those with and without existing cardiovascular disease or diabetes mellitus. Conclusions and Relevance Among people reporting any activity, there was an inverse dose-response relationship between proportion of vigorous activity and mortality. Our findings suggest that vigorous activities should be endorsed in clinical and public health activity guidelines to maximize the population benefits of physical activity.

Year2015
JournalJAMA Internal Medicine
Digital Object Identifier (DOI)https://doi.org/10.1001/jamainternmed.2015.0541
Research GroupSchool of Allied Health
Publisher's version
File Access Level
Controlled
Permalink -

https://acuresearchbank.acu.edu.au/item/89741/effect-of-moderate-to-vigorous-physical-activity-on-all-cause-mortality-in-middle-aged-and-older-australians

Restricted files

Publisher's version

  • 138
    total views
  • 0
    total downloads
  • 0
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

The 2018 physical activity guidelines for Americans: What’s new? Implications for clinicians and the public
Stamatakis, Emmanuel, Straker, Leon, Hamer, Mark and Gebel, Klaus. (2019). The 2018 physical activity guidelines for Americans: What’s new? Implications for clinicians and the public. Journal of Orthopaedic and Sports Physical Therapy. 49(7), pp. 487-490. https://doi.org/10.2519/jospt.2019.0609
Effects of new dock-less bicycle-sharing programs on cycling: A retrospective study in Shanghai
Jia, Yingnan, Ding, Ding, Gebel, Klaus, Chen, Lili, Zhang, Sen, Ma, Zhicong and Fu, Hua. (2019). Effects of new dock-less bicycle-sharing programs on cycling: A retrospective study in Shanghai. BMJ Open. 9(2), pp. 1 - 9. https://doi.org/10.1136/bmjopen-2018-024280
Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults
Lopez, Juan Pablo Rey, Gebel, Klaus, Chia, Debbie and Stamatakis, Emmanuel. (2019). Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults. BMJ Open Sport & Exercise Medicine. 5(1), pp. 1 - 8. https://doi.org/10.1136/bmjsem-2019-000596
Moving to an active lifestyle? A systematic review of the effects of residential relocation on walking, physical activity and travel behaviour
Ding, Ding, Nguyen, Binh, Learnihan, Vincent, Bauman, Adrian E., Davey, Rachel, Jalaludin, Bin and Gebel, Klaus. (2018). Moving to an active lifestyle? A systematic review of the effects of residential relocation on walking, physical activity and travel behaviour. British Journal of Sports Medicine. 52(12), pp. 789 - 799. https://doi.org/10.1136/bjsports-2017-098833
Walking lowers mortality risk in older US adults
Gebel, Klaus and Ding, Ding. (2018). Walking lowers mortality risk in older US adults. Evidence-Based Medicine. 23(5), pp. 187 - 188. https://doi.org/10.1136/bmjebm-2018-110902
Mobile bicycle sharing: The social trend that may change how we move
Ding, Ding, Jia, Yingnan and Gebel, Klaus. (2018). Mobile bicycle sharing: The social trend that may change how we move. The Lancet Public Health. 3(5), pp. 215 - 215. https://doi.org/10.1016/S2468-2667(18)30066-5
Sitting time and physical function in Australian retirees: An analysis of bidirectional relationships
Gardiner, Paul A., Reid, Natasha, Gebel, Klaus and Ding, Ding. (2018). Sitting time and physical function in Australian retirees: An analysis of bidirectional relationships. The Journals of Gerontology: Series A. 73(12), pp. 1675 - 1681. https://doi.org/10.1093/gerona/gly008
Removal of sugary drinks from vending machines: An Australian university case study
Tsai, Carrie, Slater, Scott, Ronto, Rimante, Gebel, Klaus and Wu, Jason H.Y.. (2018). Removal of sugary drinks from vending machines: An Australian university case study. Australian and New Zealand Journal of Public Health. 42(6), pp. 588 - 588. https://doi.org/10.1111/1753-6405.12827
Patterns and predictors of sitting time over ten years in a large population-based Canadian sample: Findings from the Canadian Multicentre Osteoporosis Study (CaMos)
Gebel, Klaus, Pont, Sarah, Ding, Ding, Bauman, Adrian E., Chau, Josephine Y., Berger, Claudie and Prior, Jerilynn C.. (2017). Patterns and predictors of sitting time over ten years in a large population-based Canadian sample: Findings from the Canadian Multicentre Osteoporosis Study (CaMos). Preventive Medicine Reports. 5, pp. 289 - 294. https://doi.org/10.1016/j.pmedr.2017.01.015
Perceived barriers and enablers to participation in a community-tailored physical activity program with Indigenous Australians in a regional and rural setting: A qualitative study
Sushames, Ashleigh, Engelberg, Terry and Gebel, Klaus. (2017). Perceived barriers and enablers to participation in a community-tailored physical activity program with Indigenous Australians in a regional and rural setting: A qualitative study. International Journal for Equity in Health. 16(1), pp. 1 - 9. https://doi.org/10.1186/s12939-017-0664-1
Do physical activity interventions in Indigenous people in Australia and New Zealand improve activity levels and health outcomes? A systematic review
Sushames, Ashleigh, van Ufffelen, Jannique and Gebel, Klaus. (2016). Do physical activity interventions in Indigenous people in Australia and New Zealand improve activity levels and health outcomes? A systematic review. International Journal of Behavioral Nutrition and Physical Activity. https://doi.org/10.1186/s12966-016-0455-x
Validity and reliability of fitbit flex for step count, moderate to vigorous physical activity and activity energy expenditure
Sushames, Ashleigh, Edwards, Andrew, Thompson, Fintan, McDermott, Robyn and Gebel, Klaus. (2016). Validity and reliability of fitbit flex for step count, moderate to vigorous physical activity and activity energy expenditure. PLoS ONE. 11(9), pp. 1 - 14. https://doi.org/10.1371/journal.pone.0161224
Correcting bias in self-rated quality of life: An application of anchoring vignettes and ordinal regression models to better understand QoL differences across commuting modes
Crane, Melanie, Rissel, Chris, Greaves, Stephen and Gebel, Klaus. (2016). Correcting bias in self-rated quality of life: An application of anchoring vignettes and ordinal regression models to better understand QoL differences across commuting modes. Quality of Life Research. https://doi.org/10.1007/s11136-015-1090-8
Improving current practice in reviews of the built environment and physical activity
Gebel, Klaus, Ding, Ding, Foster, Charlie, Bauman, Adrian E. and Sallis, James F.. (2015). Improving current practice in reviews of the built environment and physical activity. Sports Medicine. 45(3), pp. 297 - 302. https://doi.org/10.1007/s40279-014-0273-8
Vigorous physical activity and all-cause mortality: A story that got lost in translation
Ding, Ding, Gebel, Klaus, Freeman, Becky and Bauman, Adrian. (2015). Vigorous physical activity and all-cause mortality: A story that got lost in translation. Journal of Physical Activity and Health. 12(4), pp. 445 - 446. https://doi.org/10.1123/jpah.2015-0291
Neighborhood walkability, fear and risk of falling and response to walking promotion: The Easy Steps to Health 12-month randomized controlled trial
Merom, Dafna, Gebel, Klaus, Fahey, Paul P., Astell-Burt, Thomas, Voukelatos, Alexander, Rissel, Chris and Sherrington, Catherine. (2015). Neighborhood walkability, fear and risk of falling and response to walking promotion: The Easy Steps to Health 12-month randomized controlled trial. Preventive Medicine Reports. 2, pp. 704 - 710. https://doi.org/10.1016/j.pmedr.2015.08.011
Co-benefits of designing communities for active living: An exploration of literature
Sallis, James F., Spoon, Chad, Cavill, Nick, Engelberg, Jessa K., Gebel, Klaus, Parker, Mike, Thornton, Christina M., Lou, Debbie, Wilson, Amanda, Cutter, Carmen L. and Ding, Ding. (2015). Co-benefits of designing communities for active living: An exploration of literature. International Journal of Behavioral Nutrition and Physical Activity. 12(1), pp. 1 - 10. https://doi.org/10.1186/s12966-015-0188-2
An early-stage epidemic: A systematic review of correlates of smoking among Chinese women
Ding, Ding, Gebel, Klaus, Oldenburg, Brian, Wan, Xia, Zhong, Xuefeng and Novotny, Thomas E.. (2014). An early-stage epidemic: A systematic review of correlates of smoking among Chinese women. International Journal of Behavioral Medicine. https://doi.org/10.1007/s12529-013-9367-1
Longer Term Impact of the Mass Media Campaign to Promote the Get Healthy Information and Coaching Service®: Increasing the Saliency of a New Public Health Program
O'Hara, Blythe J., Phongsavan, Philayrath, Gebel, Klaus, Banovic, Debbie, Buffett, Kym M. and Bauman, Adrian. (2014). Longer Term Impact of the Mass Media Campaign to Promote the Get Healthy Information and Coaching Service®: Increasing the Saliency of a New Public Health Program. Health Promotion Practice. https://doi.org/10.1177/1524839914524774
Driving: A road to unhealthy lifestyles and poor health outcomes
Ding, Ding, Gebel, Klaus, Phongsavan, Philayrath, Bauman, Adrian E. and Merom, Dafna. (2014). Driving: A road to unhealthy lifestyles and poor health outcomes. PLoS ONE. 9(6), pp. 1 - 5. https://doi.org/10.1371/journal.pone.0094602
Volume and intensity of physical activity in a large population-based cohort of middle-aged and older Australians: Prospective relationships with weight gain, and physical function
Gebel, Klaus, Ding, Ding and Bauman, Adrian E.. (2014). Volume and intensity of physical activity in a large population-based cohort of middle-aged and older Australians: Prospective relationships with weight gain, and physical function. Preventive Medicine. https://doi.org/10.1016/j.ypmed.2013.12.030
Self-efficacy, physical activity, and sedentary behavior in adolescent girls: Testing mediating effects of the perceived school and home environment
Plotnikoff, Ronald C., Gebel, Klaus and Lubans, David Revalds. (2014). Self-efficacy, physical activity, and sedentary behavior in adolescent girls: Testing mediating effects of the perceived school and home environment. Journal of Physical Activity and Health. https://doi.org/10.1123/jpah.2012-0414
Walkability parameters, active transportation and objective physical activity: moderating and mediating effects of motor vehicle ownership in a cross-sectional study
Eriksson, Ulf, Arvidsson, Daniel, Gebel, Klaus, Ohlsson, Henrik and Sundquist, Kristina. (2012). Walkability parameters, active transportation and objective physical activity: moderating and mediating effects of motor vehicle ownership in a cross-sectional study. International Journal of Behavioral Nutrition and Physical Activity. https://doi.org/10.1186/1479-5868-9-123
Built environment, physical activity, and obesity: What have we learned from reviewing the literature?
Ding, Ding and Gebel, Klaus. (2012). Built environment, physical activity, and obesity: What have we learned from reviewing the literature? Health and Place. https://doi.org/10.1016/j.healthplace.2011.08.021
Does the environment moderate the impact of a mass media campaign to promote walking?
Gebel, Klaus, Bauman, Adrian, Reger-Nash, Bill and Leyden, Kevin M.. (2011). Does the environment moderate the impact of a mass media campaign to promote walking? American Journal of Health Promotion. https://doi.org/10.4278/ajhp.081104-ARB-269
The Toronto Charter for Physical Activity (Die Toronto-Charta fur Bewegung)
Siefken, Katja, Kahlmeier, Sonja, Titze, Sylvia and Gebel, Klaus. (2011). The Toronto Charter for Physical Activity (Die Toronto-Charta fur Bewegung). Pravention und Gesundheitsforderung. 6(3), pp. 212 - 215. https://doi.org/10.1007/s11553-011-0303-4
Mismatch between perceived and objectively assessed neighborhood walkability attributes: Prospective relationships with walking and weight gain
Gebel, Klaus, Bauman, Adrian E., Sugiyama, Takemi and Owen, Neville. (2011). Mismatch between perceived and objectively assessed neighborhood walkability attributes: Prospective relationships with walking and weight gain. Health and Place. 17(2), pp. 519 - 524. https://doi.org/10.1016/j.healthplace.2010.12.008