Cost-effective but clinically inapproriate: new nice intervention thresholds in osteoporosis (technology appraisal 464)
Journal article
Harvey, Nicholas C., McCloskey, Eugene, Kanis, John, Compston, J E. and Cooper, Cath. (2018). Cost-effective but clinically inapproriate: new nice intervention thresholds in osteoporosis (technology appraisal 464). Osteoporosis International. 29(7), pp. 1511 - 1513. https://doi.org/10.1007/s00198-018-4505-x
Authors | Harvey, Nicholas C., McCloskey, Eugene, Kanis, John, Compston, J E. and Cooper, Cath |
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Abstract | Purpose To comment on the latest technology appraisal of the National Institute for Clinical Excellence (NICE) in osteoporosis. Methods Review of NICE Technology Appraisal (TA464) on bisphosphonate use in osteoporosis. Results The NICE appraisal on bisphosphonate use in osteoporosis indicates that treatment with oral bisphosphonates may be instituted at a FRAX 10-year probability of major osteoporotic fracture above 1%. Implementation would mean that all women aged 50 years or older are deemed eligible for treatment, a position that would increase the burden of rare long-term side effects across the population. Conclusion Cost-effectiveness thresholds for low-cost interventions should not be used to set intervention thresholds but rather to validate the implementation of clinically driven intervention thresholds. |
Year | 2018 |
Journal | Osteoporosis International |
Journal citation | 29 (7), pp. 1511 - 1513 |
Publisher | Springer UK |
ISSN | 0937-941X |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s00198-018-4505-x |
Page range | 1511 - 1513 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
Place of publication | United Kingdom |
Editors | J. A.Kanis and F. Cosman |
https://acuresearchbank.acu.edu.au/item/899qz/cost-effective-but-clinically-inapproriate-new-nice-intervention-thresholds-in-osteoporosis-technology-appraisal-464
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