Decision-making ability in current and past users of opiates : A meta-analysis
Journal article
Biernacki, Kathryn, McLennan, Skye N., Terrett, Gill and Rendell, Peter G.. (2016). Decision-making ability in current and past users of opiates : A meta-analysis. Neuroscience and Biobehavioral Reviews. 71, pp. 342-351. https://doi.org/10.1016/j.neubiorev.2016.09.011
Authors | Biernacki, Kathryn, McLennan, Skye N., Terrett, Gill and Rendell, Peter G. |
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Abstract | Opiate use is associated with deficits in decision-making. However, the impact of abstinence and co-morbid factors, like head injury and poly-substance abuse, on this ability, is currently unclear. This meta-analysis aimed to assess 1) the magnitude of decision-making deficits in opiate users; 2) whether co-morbid factors moderate the severity of these deficits; 3) whether ex-opiate users demonstrate smaller decision-making deficits than current users; and 4) whether the length of abstinence is related to the magnitude of decision-making deficits. We analysed 22 studies that compared the performance of current and ex-opiate users to healthy controls on decision-making measures such as the Iowa Gambling Task. Current users demonstrated a moderately strong impairment in decision-making relative to controls, which was not significantly moderated by co-morbid factors. The magnitude of the impairment did not significantly differ between studies assessing current or ex-users, and this impairment was not related to length of abstinence. Thus, it appears that opiate users have relatively severe decision-making deficits that persist at least 1.5 years after cessation of use. |
Keywords | decision-making; cognition; impulsivity; opiate; heroin; abstinent; addiction |
Year | 2016 |
Journal | Neuroscience and Biobehavioral Reviews |
Journal citation | 71, pp. 342-351 |
Publisher | Elsevier Ltd |
ISSN | 0149-7634 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.neubiorev.2016.09.011 |
Scopus EID | 2-s2.0-84988457045 |
Open access | Published as green open access |
Page range | 342-351 |
Funder | Australian Catholic University (ACU) |
Author's accepted manuscript | License File Access Level Open |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 17 Sep 2016 |
Publication process dates | |
Accepted | 15 Sep 2016 |
https://acuresearchbank.acu.edu.au/item/89zv7/decision-making-ability-in-current-and-past-users-of-opiates-a-meta-analysis
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Author's accepted manuscript
AM_Biernacki_2016_Decision_making_ability_in_current_and.pdf | |
License: CC BY-NC-ND 4.0 | |
File access level: Open |
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