Acute endurance exercise induces nuclear p53 abundance in human skeletal muscle
Journal article
Tachtsis, Bill, Smiles, William, Lane, Steven C., Hawley, John Alan and Camera, Donny Michael. (2016). Acute endurance exercise induces nuclear p53 abundance in human skeletal muscle. Frontiers in Physiology. 7(144), pp. 1 - 10. https://doi.org/10.3389/fphys.2016.00144
Authors | Tachtsis, Bill, Smiles, William, Lane, Steven C., Hawley, John Alan and Camera, Donny Michael |
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Abstract | The tumor suppressor protein p53 may have regulatory roles in exercise response-adaptation processes such as mitochondrial biogenesis and autophagy, although its cellular location largely governs its biological role. We investigated the subcellular localization of p53 and selected signaling targets in human skeletal muscle following a single bout of endurance exercise. |
Keywords | mitochondrial biogenesis; autophagy; mitochondrial turnover; cell signaling; skeletal muscle |
Year | 2016 |
Journal | Frontiers in Physiology |
Journal citation | 7 (144), pp. 1 - 10 |
Publisher | Frontiers Research Foundation |
ISSN | 1664-042X |
Digital Object Identifier (DOI) | https://doi.org/10.3389/fphys.2016.00144 |
Scopus EID | 2-s2.0-84966711377 |
Open access | Open access |
Page range | 1 - 10 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | License |
Place of publication | Switzerland |
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License: CC BY 4.0 |
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