Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys

Journal article

Cooper, David, Ahamed, Yasmin, Macdonald, Heather and McKay, Heather. (2008). Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
AuthorsCooper, David, Ahamed, Yasmin, Macdonald, Heather and McKay, Heather
Abstract

Background: Inter-individual differences in cortical bone volumetric density (CoD), such as those related to sex, are a product of differences in remodelling rates. While cortical bone is often treated as a uniform tissue, remodelling rates also vary within individual bones. This level of adaptation has largely been overlooked in analyses of peripheral quantitative computed tomography (pQCT) images. Further, such variation in CoD has never been assessed in growing bones. We hypothesised that CoD varied significantly within the same cross-section of the mid-tibia of adolescents. We further hypothesised that due to the profound impact of oestrogen on remodelling, this variation would be different between sexes.

Year2008
JournalBritish Journal of Sports Medicine
Journal citation42 (8), pp. 690 - 695
ISSN0306-3674
Digital Object Identifier (DOI)https://doi.org/10.1136/bjsm.2008.049528
Page range690 - 695
Research GroupMary MacKillop Institute for Health Research
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