Assessing stability in mild and moderate Parkinson's disease : Can clinical measures provide insight?
Journal article
Hubble, Ryan P., Silburn, Peter A., Naughton, Geraldine A. and Cole, Michael H.. (2016). Assessing stability in mild and moderate Parkinson's disease : Can clinical measures provide insight? Gait & Posture. 49(1), pp. 7-13. https://doi.org/10.1016/j.gaitpost.2016.06.002
Authors | Hubble, Ryan P., Silburn, Peter A., Naughton, Geraldine A. and Cole, Michael H. |
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Abstract | This cross-sectional study aimed to investigate the relationship between accelerometer-derived measures of movement rhythmicity and clinical measures of mobility, balance confidence and gait difficulty in people with Parkinson’s disease (PD). Twenty-nine independently-living PD patients (Hoehn & Yahr Stages 1–3) with no history of significant injury or orthopaedic/deep brain stimulation surgery were recruited from a database of patients who had expressed an interest to participate in research. Participants completed clinical assessments of mobility, postural stability, balance confidence and symptom severity, while head and trunk rhythmicity was evaluated during gait using accelerometers. Following data collection, patients were stratified based on disease stage into either a Mild (Hoehn & Yahr Stage 1) or Moderate (Hoehn & Yahr Stages 2–3) PD group. The results highlighted that the Moderate PD group had poorer quality of life, reduced balance confidence and increased gait and falls difficulty. Furthermore, for these patients, gait disability and the number of previous falls were both negatively correlated with multiple components of head and trunk rhythmicity. For the Mild PD group, six-meter walk time was positively correlated with ML head rhythmicity and linear regression highlighted a significant predictive relationship between these outcomes. For the Mild and Moderate PD groups, balance confidence respectively predicted anterior-posterior trunk rhythmicity and vertical head rhythmicity. While these findings demonstrate that falls history and the Gait and Falls questionnaire provide moderate insight into head and trunk rhythmicity in Moderate PD patients, objective and clinically-feasible measures of postural instability would assist with the management of these symptoms. |
Keywords | Parkinson's disease; motor control; falls; quality of life; postural stability |
Year | 2016 |
Journal | Gait & Posture |
Journal citation | 49 (1), pp. 7-13 |
Publisher | Elsevier B.V. |
ISSN | 0966-6362 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.gaitpost.2016.06.002 |
Scopus EID | 2-s2.0-84975493679 |
Open access | Published as green open access |
Research or scholarly | Research |
Page range | 7-13 |
Research Group | Sports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre |
Author's accepted manuscript | License File Access Level Open |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 05 Jun 2016 |
Publication process dates | |
Accepted | 03 Jun 2016 |
https://acuresearchbank.acu.edu.au/item/8qw9q/assessing-stability-in-mild-and-moderate-parkinson-s-disease-can-clinical-measures-provide-insight
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Author's accepted manuscript
AM_Hubble_2016_Clinically_assessing_postural_stability_in_Parkinsons.pdf | |
License: CC BY-NC-ND 4.0 | |
File access level: Open |
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