Short-term transcriptome and microRNAs responses to exposure to different air pollutants in two population studies
Journal article
Espín-Pérez, Almudena, Krauskopf, Julian, Chadeau-Hyam, Marc, van Veldhoven, Karin, Chung, Fan, Cullinan, Paul, Piepers, Jolanda, van Herwijnen, Marcel, Kubesch, Nadine, Carrasco-Turigas, Glòria, Nieuwenhuijsen, Mark, Vineis, Paolo, Kleinjans, J. and de Kok, O. M. C. M.. (2018). Short-term transcriptome and microRNAs responses to exposure to different air pollutants in two population studies. Environmental Pollution. 242, pp. 182 - 190. https://doi.org/10.1016/j.envpol.2018.06.051
Authors | Espín-Pérez, Almudena, Krauskopf, Julian, Chadeau-Hyam, Marc, van Veldhoven, Karin, Chung, Fan, Cullinan, Paul, Piepers, Jolanda, van Herwijnen, Marcel, Kubesch, Nadine, Carrasco-Turigas, Glòria, Nieuwenhuijsen, Mark, Vineis, Paolo, Kleinjans, J. and de Kok, O. M. C. M. |
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Abstract | Diesel vehicle emissions are the major source of genotoxic compounds in ambient air from urban areas. These pollutants are linked to risks of cardiovascular diseases, lung cancer, respiratory infections and adverse neurological effects. Biological events associated with exposure to some air pollutants are widely unknown but applying omics techniques may help to identify the molecular processes that link exposure to disease risk. Most data on health risks are related to long-term exposure, so the aim of this study is to investigate the impact of short-term exposure (two hours) to air pollutants on the blood transcriptome and microRNA expression levels. |
Keywords | Air pollution; Transcriptome; microRNA; Short-term exposure |
Year | 2018 |
Journal | Environmental Pollution |
Journal citation | 242, pp. 182 - 190 |
Publisher | Pergamon |
ISSN | 0269-7491 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.envpol.2018.06.051 |
Scopus EID | 2-s2.0-85049877260 |
Page range | 182 - 190 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
Place of publication | United Kingdom |
Editors | D. Carpenter and E. Zeng |
https://acuresearchbank.acu.edu.au/item/8qwq3/short-term-transcriptome-and-micrornas-responses-to-exposure-to-different-air-pollutants-in-two-population-studies
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