Rediscovering Heart Failure: The contemporary burden and profile of heart failure in Australia

Report


Chan, Yih-Kai, Gerber, Tracey, Tuttle, Camilla, Ball, Jocasta, Teng, Tiew-Hwa Katherine, Ahamed, Yasmin and Carrington, Melinda. (2015) Rediscovering Heart Failure: The contemporary burden and profile of heart failure in Australia Melbourne, Australia: Mary MacKillop Institute for Health Research.
AuthorsChan, Yih-Kai, Gerber, Tracey, Tuttle, Camilla, Ball, Jocasta, Teng, Tiew-Hwa Katherine, Ahamed, Yasmin and Carrington, Melinda
Abstract

We undertook a study of the contemporary burden of heart failure to complement a previous report released more than a decade ago. During that time, a combination of population dynamics (an ageing population), an evolving armoury of therapeutics to treat the traditional drivers of heart failure (coronary artery disease and hypertension) and a changing risk factor profile (with more diabetes and obesity than ever before) had the potential to either reduce or increase the impact and burden of heart failure from a whole society perspective.

At the same time, the definition of heart failure has evolved and this has provided an extra dimension to the burden it imposes; even if the therapeutic options for affected individuals with so-called heart failure with preserved ejection fraction or diastolic heart failure is limited.

We would emphasise that estimating the “theoretical” burden of heart failure based on systematic screening of representative samples from whole populations as an accurate picture of the “actual” clinical burden of heart failure based on real-word clinical practice is fraught with danger and uncertainty. Some of the figures in this report only make sense if you accept that a problem is only as big as you can quantify it. In so-called Rumsfeld speak we quantify both the “known-known” and the “known-unknown” aspects of heart failure from a population to clinical burden perspective.

Noting the above caveats, utilising contemporary Australian data (including the Western Australia Linkage data-set and the landmark Canberra Heart Study), we were able to update our estimates and provide, what we would regard as a valid and relatively accurate picture of the contemporary burden imposed by heart failure in Australia from an individual to whole society perspective. We would emphasise that much of this burden remains hidden. However, this hidden burden can be likened to the submerged iceberg that feeds the incident cases of clinical heart failure in our community.

Year2015
PublisherMary MacKillop Institute for Health Research
Place of publicationMelbourne, Australia
Web address (URL)http://mmihr.acu.edu.au/wp-content/uploads/sites/2/2015/08/v4-Reduced-Rediscovering-Heart-Failure-Burden_Report-August-2015-2.pdf
Open accessOpen access
Research GroupMary MacKillop Institute for Health Research
Publisher's version
ISBN978-1-922097-33-0
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Stewart, Simon, Chan, Yih-Kai, Wong, Chiew, Jennings, Garry, Scuffham, Paul, Esterman, Adrian and Carrington, Melinda. (2015) Impact of a nurse-led home and clinic-based secondary prevention programme to prevent cardiac dysfunction in high risk individuals : The Nurse-led Intervention for Less Chronic Heart Failure (NIL-CHF) randomized controlled study. European Journal of Heart Failure. 17, pp. 620 - 630. https://doi.org/10.1002/ejhf.272
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Salmon, Vasiliki, Frost, Steven, Newton, Phillip, Macdonald, Peter, Stewart, Simon, Carrington, Melinda, Chan, Yih and Davidson, Patricia. (2015) A cluster-randomized controlled trial to reduce sedentary behavior and promote physical activity and health of 8-9 year olds: The Transform-Us! Study. BMC Public Health. 24(11), pp. 1068 - 1073. https://doi.org/10.1186/1471-2458-11-759
Cost-effectiveness of a home based intervention for secondary prevention of readmission with chronic heart disease
Byrnes, Joshua, Carrington, Melinda, Chan, Yih-Kai, Pollicino, Christine, Dubrowin, Natalie and Stewart, Simon. (2015) Cost-effectiveness of a home based intervention for secondary prevention of readmission with chronic heart disease. PLoS ONE. 10(12), pp. 1 - 13. https://doi.org/10.1371/journal.pone.0144545
Systematic review of model-based analyses reporting the cost-effectiveness and cost-utility of cardiovascular disease management programs
Maru, Shoko, Byrnes, Joshua, Whitty, Jennifer, Carrington, Melinda, Stewart, Simon and Scuffham, Paul. (2015) Systematic review of model-based analyses reporting the cost-effectiveness and cost-utility of cardiovascular disease management programs. European Journal of Cardiovascular Nursing. 14(1), pp. 26 - 33. https://doi.org/10.1177/1474515114536093
Investigating acute satiation and meal termination effects of a commercial lipid emulsion : A breakfast meal study
Poppitt, Sally, Han, Shuang, Strik, Caroline, Kindleysides, Sophie and Chan, Yih-Kai. (2015) Investigating acute satiation and meal termination effects of a commercial lipid emulsion : A breakfast meal study. Physiology & Behavior. 152, pp. 20 - 25. https://doi.org/10.1016/j.physbeh.2015.09.008
Cost-effectiveness of home versus clinic-based management of chronic heart failure: Extended follow-up of pragmatic, multicentre randomized trial cohort - The WHICH? Study
Maru, Shoko, Byrnes, Joshua, Carrington, Melinda J., Chan, Yih-Kai, Thompson, David R., Stewart, Simon and Scuffham, Paul A.. (2015) Cost-effectiveness of home versus clinic-based management of chronic heart failure: Extended follow-up of pragmatic, multicentre randomized trial cohort - The WHICH? Study. International Journal of Cardiology. 201, pp. 368 - 375. https://doi.org/10.1016/j.ijcard.2015.08.066
Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival : Pragmatic, multicentre, randomised controlled trial
Stewart, Simon, Ball, Jocasta, Horowitz, John D., Marwick, Thomas H., Mahadevan, Gnanadevan, Wong, Chiew, Abhayaratna, Walter P., Chan, Yih K., Esterman, Adrian, Thompson, David R., Scuffham, Paul and Carrington, Melinda J.. (2015) Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival : Pragmatic, multicentre, randomised controlled trial. The Lancet. 385(9970), pp. 775 - 784. https://doi.org/10.1016/S0140-6736(14)61992-9
Cardiometabolic risk and disease in Indigenous Australians: The heart of the heart study
Brown, Alex, Carrington, Melinda Jane, McGrady, Michele, Lee, Geraldine, Zeitz, Christopher, Krum, Henry, Rowley, Kevin and Stewart, Simon. (2014) Cardiometabolic risk and disease in Indigenous Australians: The heart of the heart study. International Journal of Cardiology. 171(3), pp. 377 - 383. https://doi.org/10.1016/j.ijcard.2013.12.026
Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes
Bryant, Christina, Lewis, Prudence, Bennell, Kim, Ahamed, Yasmin, Crough, Denae, Jull, Gwendolen, Kenardy, Justin, Nicholas, Michael and Keefe, Francis. (2014) Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes. Physical Therapy. 94(10), pp. 1443 - 1454. https://doi.org/10.2522/ptj.20130444
Predictors of mean arterial pressure morning rate of rise and power function in subjects undergoing ambulatory blood pressure recording
Head, Geoffrey, Andrianopoulos, Nick, McGrath, Barry, Martin, Catherine, Carrington, Melinda, Lukoshkova, Elena, Davern, Pamela, Jennings, Garry and Reid, Christopher. (2014) Predictors of mean arterial pressure morning rate of rise and power function in subjects undergoing ambulatory blood pressure recording. PLoS ONE. 9(3), pp. 1 - 10. https://doi.org/10.1371/journal.pone.0093186
Cardiovascular disease prevention via a nurse-facilitated intervention clinic in a regional setting : The Protecting Healthy Hearts Program
Carrington, Melinda and Stewart, Simon. (2014) Cardiovascular disease prevention via a nurse-facilitated intervention clinic in a regional setting : The Protecting Healthy Hearts Program. European Journal of Cardiovascular Nursing. 14(4), pp. 1 - 10. https://doi.org/10.1177/1474515114537022
Prolonged impact of home versus clinic-based management of chronic heart failure: Extended follow-up of a pragmatic, multicentre randomized trial cohort
Stewart, Simon, Carrington, Melinda, Horowitz, John, Marwick, Thomas, Newton, Phillip, Davidson, Patricia, Macdonald, Peter, Thompson, David R., Chan, Yih Kai and Krum, Henry. (2014) Prolonged impact of home versus clinic-based management of chronic heart failure: Extended follow-up of a pragmatic, multicentre randomized trial cohort. International Journal of Cardiology. 174(3), pp. 600 - 610. https://doi.org/10.1016/j.ijcard.2014.04.164
Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes
Bryant, Christina, Lewis, Prudence, Bennell, Kim, Ahamed, Yasmin, Crough, Denae, Jull, Gwendolen, Kenardy, Justin, Nicholas, Michael and Keefe, Francis. (2014) Can physical therapists deliver a pain coping skills program? An examination of training processes and outcomes. Physical Therapy. 94(10), pp. 1443 - 1454. https://doi.org/10.2522/ptj.20130444
Cardiometabolic risk and disease in Indigenous Australians : The heart of the heart study
Brown, Alex, Carrington, Melinda, McGrady, Michele, Lee, Geraldine, Zeitz, Christopher, Krum, Henry, Rowley, Kevin and Stewart, Simon. (2014) Cardiometabolic risk and disease in Indigenous Australians : The heart of the heart study. International Journal of Cardiology. 171, pp. 377 - 383. https://doi.org/10.1016/j.ijcard.2013.12.026
Post-discharge electrocardiogram Holter monitoring in recently hospitalized individuals with chronic atrial fibrillation to enhance therapeutic monitoring and identify potentially predictive phenotypes
Ball, Jocasta Clare, Carrington, Melinda Jane, Thompson, David, Horowitz, John and Stewart, Simon. (2014) Post-discharge electrocardiogram Holter monitoring in recently hospitalized individuals with chronic atrial fibrillation to enhance therapeutic monitoring and identify potentially predictive phenotypes. European Journal of Cardiovascular Nursing. https://doi.org/10.1177/1474515114547650
Lower levels of high-density lipoprotein cholesterol in urban Africans presenting with communicable versus non-communicable forms of heart disease : The 'Heart of Soweto' hospital registry study
Lyons, Jasmine, Sliwa, Karen, Carrington, Melinda, Raal, Frederick, Pretorius, Sandra, Thienemann, Friedrich and Stewart, Simon. (2014) Lower levels of high-density lipoprotein cholesterol in urban Africans presenting with communicable versus non-communicable forms of heart disease : The 'Heart of Soweto' hospital registry study. BMJ Open. 4(7), pp. 1 - 8. https://doi.org/10.1136/bmjopen-2014-005069
Long-term tolerance and efficacy of adjunctive exenatide therapy on glycaemic control and bodyweight in type 2 diabetes: A retrospective study from a specialist diabetes outpatient clinic
Carrington, Melinda Jane, Chan, Yih, Stewart, Simon, Sjourke, B., Brazilek, R. and Cohen, N.. (2014) Long-term tolerance and efficacy of adjunctive exenatide therapy on glycaemic control and bodyweight in type 2 diabetes: A retrospective study from a specialist diabetes outpatient clinic. Internal Medicine Journal. 44(4), pp. 345 - 353. https://doi.org/10.1111/imj.12377
Redefining the ECG in urban South Africans : Electrocardiographic findings in heart disease-free Africans
Sliwa, Karen, Lee, Geraldine, Carrington, Melinda, Obel, Pro and Stewart, Simon. (2013) Redefining the ECG in urban South Africans : Electrocardiographic findings in heart disease-free Africans. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2012.06.005
Alternating bouts of sitting and standing attenuate postprandial glucose responses
Thorp, Michael, Keefe, Francis, Bryant, Christina, Metcalf, Ben, Ahamed, Yasmin, Nicholas, Michael and Bennell, Kim. (2013) Alternating bouts of sitting and standing attenuate postprandial glucose responses. Medicine and Science in Sports and Exercise. 20(2), pp. 106 - 112. https://doi.org/10.1249/MSS.0000000000000337
Time from symptoms to definitive diagnosis of idiopathic pulmnary arterial hypertension : The delay study
Strange, Geoff, Kermeen, Fiona, Gabbay, Eli, Williams, Trevor, Carrington, Melinda, Stewart, Simon and Keogh, Anne. (2013) Time from symptoms to definitive diagnosis of idiopathic pulmnary arterial hypertension : The delay study. Pulmonary Circulation. https://doi.org/10.4103/2045-8932.109919
Women Versus Men with Chronic Atrial Fibrillation: insights from the Standard Versus Atrial Fibrillation spEcific managemenT studY (SAFETY)
Ball, Jocasta, Carrington, Melinda, Wood, Kathryn and Stewart, Simon. (2013) Women Versus Men with Chronic Atrial Fibrillation: insights from the Standard Versus Atrial Fibrillation spEcific managemenT studY (SAFETY). PLoS ONE. 8(5), pp. 1 - 9. https://doi.org/10.1371/journal.pone.0065795
Determinants of achieving early blood pressure control with monotherapy in a primary care setting
Stewart, Simon, Carrington, Melinda, Swemmer, Carla, Kurstjens, Nicol, Brown, Alex, Burrell, Louise, Nelson, Mark, Stocks, Nigel and Jennings, Garry. (2013) Determinants of achieving early blood pressure control with monotherapy in a primary care setting. Journal of Clinical Hypertension. https://doi.org/10.1111/jch.12164
Profile and burden of an evolving epidemic in the 21st century
Ball, Jocasta, Carrington, Melinda, McMurray, J and Stewart, Simon. (2013) Profile and burden of an evolving epidemic in the 21st century. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2012.12.093
A multicenter, randomized trial of a nurse-led, home-based intervention for optimal secondary cardiac prevention suggests some benefits for men but not for women : the Young at Heart Study
Carrington, Melinda, Chan, Yih Kai, Calderone, Alicia, Scuffham, Paul, Esterman, Adrian and Goldstein, Stan. (2013) A multicenter, randomized trial of a nurse-led, home-based intervention for optimal secondary cardiac prevention suggests some benefits for men but not for women : the Young at Heart Study. Circulation: Cardiovascular Quality and Outcomes. https://doi.org/10.1161/CIRCOUTCOMES.111.000006
Navigating the fine line between benefit and risk in chronic atrial fibrillation : Rationale and Design of the standard versus Atrial fibrillation specific management study (SAFETY)
Carrington, Melinda, Ball, Jocasta, Horowitz, John, Marwick, Thomas, Mahadevan, Gnanadevan, Wong, Chiew, Abhayaratna, Walter, Haluska, Brian, Thompson, David and Scuffham, Paul. (2013) Navigating the fine line between benefit and risk in chronic atrial fibrillation : Rationale and Design of the standard versus Atrial fibrillation specific management study (SAFETY). International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2011.10.065
Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the Which? Trial
Stewart, Simon, Whitty, Jennifer, Carrington, Melinda, Calderone, Alicia, Marwick, Thomas, Horowitz, John, Krum, Henry, Davidson, Patricia, Macdonald, Peter and Reid, Christopher. (2013) Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the Which? Trial. PLoS ONE. 8(3), pp. 1 - 8. https://doi.org/10.1371/journal.pone.0058347
Determinants of achieving early blood pressure control with monotherapy in a primary care setting
Stewart, Simon, Carrington, Melinda, Swemmer, Carla, Kurstjens, Nicol, Brown, Alex, Burrell, Louise, Nelson, Mark, Stocks, Nigel and Jennings, Garry. (2013) Determinants of achieving early blood pressure control with monotherapy in a primary care setting. Journal of Clinical Hypertension. https://doi.org/10.1111/jch.12164
Atrial fibrillation : Profile and burden of an evolving epidemic in the 21st century
Ball, Jocasta, Carrington, Melinda, McMurray, J and Stewart, Simon. (2013) Atrial fibrillation : Profile and burden of an evolving epidemic in the 21st century. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2012.12.093
Reply: Diagnosing vascular mild cognitive impairment with atrial fibrillation remains a challenge
Ball, Jocasta. (2013) Reply: Diagnosing vascular mild cognitive impairment with atrial fibrillation remains a challenge. Heart. 99(11), pp. 819 - 820. https://doi.org/10.1136/heartjnl-2013-303965
Navigating the fine line between benefit and risk in chronic atrial fibrillation : Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY)
Carrington, Melinda, Ball, Jocasta, Horowitz, John, Marwick, Thomas, Mahadevan, Gnanadevan, Wong, Chiew, Abhayaratna, Walter, Haluska, Brian, Thompson, David and Scuffham, Paul. (2013) Navigating the fine line between benefit and risk in chronic atrial fibrillation : Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY). International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2011.10.065
Navigating the fine line between benefit and risk in chronic atrial fibrillation : Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY)
Carrington, Melinda, Ball, Jocasta, Horowitz, John, Marwick, Thomas, Mahadevan, Gnanadevan, Wong, Chiew, Abhayaratna, Walter, Haluska, Brian, Thompson, David and Scuffham, Paul. (2013) Navigating the fine line between benefit and risk in chronic atrial fibrillation : Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY). International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2011.10.065
A physiotherapist-delivered, combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis : A pilot study
Hunt, Michael, Keefe, Francis, Bryant, Christina, Metcalf, Ben, Ahamed, Yasmin, Nicholas, Michael and Bennell, Kim. (2013) A physiotherapist-delivered, combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis : A pilot study. The Knee. 20(2), pp. 106 - 112. https://doi.org/10.1016/j.knee.2012.07.008
Mild cognitive impairment in high-risk patients with chronic atrial fibrillation : A forgotten component of clinical management?
Ball, Jocasta, Carrington, Melinda and Stewart, Simon. (2013) Mild cognitive impairment in high-risk patients with chronic atrial fibrillation : A forgotten component of clinical management? Heart. https://doi.org/10.1136/heartjnl-2012-303182
The Green, Amber, Red Delineation of Risk and Need (GARDiAN) management system : A pragmatic approach to optimizing heart health from primary prevention to chronic disease management
Carrington, Melinda J., Kok, Simon and Jansen, Kiki. (2013) The Green, Amber, Red Delineation of Risk and Need (GARDiAN) management system : A pragmatic approach to optimizing heart health from primary prevention to chronic disease management. European Journal of Cardiovascular Nursing. https://doi.org/10.1177/1474515112451702
Atrial fibrillation : Profile and burden of an evolving epidemic in the 21st century
Ball, Jocasta, Carrington, Melinda, McMurray, J and Stewart, Simon. (2013) Atrial fibrillation : Profile and burden of an evolving epidemic in the 21st century. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2012.12.093
Mild cognitive impairment in high-risk patients with chronic atrial fibrillation : A forgotten component of clinical management?
Ball, Jocasta, Carrington, Melinda and Stewart, Simon. (2013) Mild cognitive impairment in high-risk patients with chronic atrial fibrillation : A forgotten component of clinical management? Heart. https://doi.org/10.1136/heartjnl-2012-303182
Pressure points in primary care : Blood pressure and management of hypertension in 532 050 patients from 2005 to 2010
Carrington, Melinda, Jennings, Garry and Stewart, Simon. (2013) Pressure points in primary care : Blood pressure and management of hypertension in 532 050 patients from 2005 to 2010. Journal of Hypertension. https://doi.org/10.1097/HJH.0b013e3283606bc7
Redefining the ECG in urban South Africans : Electrocardiographic findings in heart disease-free Africans
Sliwa, Karen, Lee, Geraldine, Carrington, Melinda, Obel, Pro, Okreglicki, Andrzeq and Stewart, Simon. (2013) Redefining the ECG in urban South Africans : Electrocardiographic findings in heart disease-free Africans. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2012.06.005
Women versus men with chronic atrial fibrillation: insights from the Standard Versus Atrial Fibrillation spEcific managemenT studY (SAFETY)
Ball, Jocasta, Carrington, Melinda, Wood, Kathryn and Stewart, Simon. (2013) Women versus men with chronic atrial fibrillation: insights from the Standard Versus Atrial Fibrillation spEcific managemenT studY (SAFETY). PLoS ONE. 8(5), pp. 1 - 9. https://doi.org/10.1371/journal.pone.0065795
Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the Which? Trial
Stewart, Simon, Whitty, Jennifer, Carrington, Melinda, Calderone, Alicia, Marwick, Thomas, Horowitz, John, Krum, Henry, Davidson, Patricia, Macdonald, Peter and Reid, Christopher. (2013) Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the Which? Trial. PLoS ONE. 8(3), pp. 1 - 8. https://doi.org/10.1371/journal.pone.0058347
Different lipid profiles according to ethnicity in the Heart of Soweto study cohort of de novo presentations of heart disease
Sliwa, Karen, Lyons, Jasmine, Carrington, Melinda, Lecour, Sandrin, Marais, A and Raal, Frederick. (2012) Different lipid profiles according to ethnicity in the Heart of Soweto study cohort of de novo presentations of heart disease. Cardiovascular Journal of Africa. 23(7), pp. 389 - 395. https://doi.org/10.5830/CVJA-2012-036
Impact of home versus clinic-based management of chronic heart failure : The WHiCH? (Which heart failure intervention is most cost-effective & consumer friendly in reducing hospital care) multicenter, randomized trial
Stewart, Simon, Carrington, Melinda, Marwick, Thomas, Davidson, Patricia, Macdonald, Peter, Horowitz, John, Krum, Henry, Newton, Phillip, Reid, Christopher and Chan, Yih Kai. (2012) Impact of home versus clinic-based management of chronic heart failure : The WHiCH? (Which heart failure intervention is most cost-effective & consumer friendly in reducing hospital care) multicenter, randomized trial. Journal of the American College of Cardiology. 60(14), pp. 1239 - 1248. https://doi.org/10.1016/j.jacc.2012.06.025
Patient preferences for the delivery of disease management in chronic heart failure : A qualitative study
Whitty, Jennifer, Carrington, Melinda, Stewart, Simon, Holliday, Julie, Marwick, Thomas and Scuffham, Paul. (2012) Patient preferences for the delivery of disease management in chronic heart failure : A qualitative study. The Journal of Cardiovascular Nursing. 27(3), pp. 201 - 207. https://doi.org/10.1097/JCN.0b013e31821abf22
Contribution of the human immunodeficiency virus/acquired immunodeficiency syndrome epidemic to de novo presentations of heart disease in the Heart of Soweto Study cohort
Sliwa, Karen, Carrington, Melinda, Becker, Anthony, Thienemann, Friedrich and Ntsekhe, Mpiko. (2012) Contribution of the human immunodeficiency virus/acquired immunodeficiency syndrome epidemic to de novo presentations of heart disease in the Heart of Soweto Study cohort. European Heart Journal. 33(7), pp. 866 - 874. https://doi.org/10.1093/eurheartj/ehr398
The 12-lead ECG in peripartum cardiomyopathy
Tibazarwa, Kemi, Lee, Geraldine, Mayosi, Bongani, Carrington, Melinda, Stewart, Simon and Sliwa, Karen. (2012) The 12-lead ECG in peripartum cardiomyopathy. Cardiovascular Journal of Africa. 23(6), pp. 322 - 329. https://doi.org/10.5830/CVJA-2012-006
Effect of intensive structured care on individual blood pressure targets in primary care : Multicentre randomised controlled trial
Stewart, Simon, Carrington, Melinda, Swemmer, Carla, Anderson, Craig, Kurstjens, Nicol, Amerena, John, Brown, Alex, Burrell, Louise, de Looze, Ferdinandus and Harris, Mark. (2012) Effect of intensive structured care on individual blood pressure targets in primary care : Multicentre randomised controlled trial. British Medical Journal. 345(7884), pp. 1 - 16. https://doi.org/10.1136/bmj.e7156
Elevated risk factors but low burden of heart disease in urban African primary care patients : A fundamental role for primary prevention
Stewart, Simon, Carrington, Melinda, Pretorius, Sandra, Ogah, Okechukwu, Blauwet, Lori, Antras-Ferry, Jocelyn and Sliwa, Karen. (2012) Elevated risk factors but low burden of heart disease in urban African primary care patients : A fundamental role for primary prevention. International Journal of Cardiology. 158(2), pp. 205 - 210. https://doi.org/10.1016/j.ijcard.2011.01.022
The emulsified lipid Fabuless (Olibra) does not decrease food intake but suppresses appetite when consumed with yoghurt but not alone or with solid foods : A food effect study
Chan, Yih, Strik, C, Budget, S, McGill, A T., Proctor, J and Poppitt, Sally. (2012) The emulsified lipid Fabuless (Olibra) does not decrease food intake but suppresses appetite when consumed with yoghurt but not alone or with solid foods : A food effect study. Physiology & Behavior. 105(3), pp. 742 - 748. https://doi.org/10.1016/j.physbeh.2011.08.042
Assessing cardiovascular risk in regional areas: The Healthy Hearts - Beyond City Limits program
Carrington, Melinda, Jennings, Garry, Clark, Robyn and Stewart, Simon. (2012) Assessing cardiovascular risk in regional areas: The Healthy Hearts - Beyond City Limits program. BMC Health Services Research. 12(1), pp. 1 - 10. https://doi.org/10.1186/1472-6963-12-296
Impact of Home Versus Clinic-Based Management of Chronic Heart Failure : The WHICH? (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care) Multicenter, Randomized Trial
Stewart, Simon, Carrington, Melinda, Marwick, Thomas, Davidson, Patricia, Macdonald, Peter, Horowitz, John, Krum, Henry, Newton, Phillip, Reid, Christopher, Chan, Yih and Scuffham, Paul. (2012) Impact of Home Versus Clinic-Based Management of Chronic Heart Failure : The WHICH? (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care) Multicenter, Randomized Trial. Journal of the American College of Cardiology. 60(14), pp. 1239 - 1248. https://doi.org/10.1016/j.jacc.2012.06.025
Exploring the potential to remain "Young @ Heart" : initial findings of a multi-centre, randomised study of nurse-led, home-based intervention in a hybrid health care system
Chan, Yih-Kai, Stewart, Simon, Calderone, Alicia, Scuffham, Paul, Goldstein, Stan and Carrington, Melinda J.. (2012) Exploring the potential to remain "Young @ Heart" : initial findings of a multi-centre, randomised study of nurse-led, home-based intervention in a hybrid health care system. International Journal of Cardiology. 154(1), pp. 52 - 58. https://doi.org/10.1016/j.ijcard.2010.08.071
A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: A randomised controlled trial protocol
Bennell, Kim, Ahamed, Yasmin, Bryant, Christina, Jull, Gwendolen, Hunt, Michael, Kenardy, Justin, Forbes, Andrew, Harris, Anthony, Nicholas, Michael, Metcalf, Ben, Egerton, Thorlene and Keefe, Francis. (2012) A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: A randomised controlled trial protocol. BMC Musculoskeletal Disorders. 13(129), pp. 1 - 17. https://doi.org/10.1186/1471-2474-13-129
Heart failure, ventricular dysfunction and risk factor prevalence in Australian Aboriginal peoples : The Heart of the Heart Study
McGrady, Michele, Krum, Henry, Carrington, Melinda, Stewart, Simon, Zeitz, Christopher, Lee, Geraldine, Marwick, Thomas, Haluska, Brian and Brown, Alex. (2012) Heart failure, ventricular dysfunction and risk factor prevalence in Australian Aboriginal peoples : The Heart of the Heart Study. Heart. 98(21), pp. 1562 - 1567. https://doi.org/10.1136/heartjnl-2012-302229
Effect of intensive structured care on individual blood pressure targets in primary care : Multicentre randomised controlled trial
Stewart, Simon, Carrington, Melinda, Swemmer, Carla, Anderson, Craig, Kurstjens, Nicol, Amerena, John, Brown, Alex, Burrell, Louise, de Looze, Ferdinandus and Harris, Mark. (2012) Effect of intensive structured care on individual blood pressure targets in primary care : Multicentre randomised controlled trial. British Medical Journal. 345(7884), pp. 1 - 16. https://doi.org/10.1136/bmj.e7156
Influence of tail versus cardiac sampling on blood glucose and lipid profiles in mice
Chan, Yih, Davis, Paul, Poppitt, Sally, Sun, Xueying, Greenhill, Nicholas, Krishnamurthi, Rita, Przerpiorski, Aneta, McGill, Anne-Thea and Krissansen, Geoffrey. (2012) Influence of tail versus cardiac sampling on blood glucose and lipid profiles in mice. Laboratory Animals. 46(2), pp. 142 - 147. https://doi.org/10.1258/la.2011.011136
The WHiCH? Trial: Rationale and design of a pragmatic randomized, multicentre comparison of home- vs. clinic-based management of chronic heart failure patients
Stewart, Simon, Carrington, Melinda J., Marwick, Thomas, Davidson, Patricia M., Macdonald, Peter, Horowitz, John, Krum, Henry, Newton, Phillip J., Reid, Christopher and Scuffham, Paul A.. (2011) The WHiCH? Trial: Rationale and design of a pragmatic randomized, multicentre comparison of home- vs. clinic-based management of chronic heart failure patients. European Journal of Heart Failure. 13(8), pp. 909 - 916. https://doi.org/10.1093/eurjhf/hfr048
The clinical consequences and challenges of hypertension in urban-dwelling black Africans :insights from the Heart of Soweto Study
Stewart, Simon, Libhaber, Elena, Carrington, Melinda, Damasceno, Albertino, Abbasi, Haroon, Hansen, Craig, Wilkinson, David and Sliwa, Karen. (2011) The clinical consequences and challenges of hypertension in urban-dwelling black Africans :insights from the Heart of Soweto Study. International Journal of Cardiology. 146(1), pp. 22 - 27. https://doi.org/10.1016/j.ijcard.2009.05.061
A not-so-rare form of heart failure in urban black Africans :Pathways to right heart failure in the Heart of Soweto Study cohort
Stewart, Simon, Mocumbi, Ana, Carrington, Melinda, Pretorius, Sandra, Burton, Rosie and Sliwa, Karen. (2011) A not-so-rare form of heart failure in urban black Africans :Pathways to right heart failure in the Heart of Soweto Study cohort. European Journal of Heart Failure. 13(10), pp. 1070 - 1077. https://doi.org/10.1093/eurjhf/hfr108
Optimising management of hypertension in primary care :The Valsartan intensified Primary Care Reduction of Blood Pressure (Viper-Bp) Study
Stewart, Simon, Carrington, Melinda, Swemmer, Carla, Kurstjens, Nicol and Jennings, Garry. (2011) Optimising management of hypertension in primary care :The Valsartan intensified Primary Care Reduction of Blood Pressure (Viper-Bp) Study. International Journal of Cardiology. 153(3), pp. 317 - 322. https://doi.org/10.1016/j.ijcard.2010.12.055
Standing at the crossroads between new and historically prevalent heart disease :Effects of migration and socio-economic factors in the Heart of Soweto cohort study
Stewart, Simon, Carrington, Melinda, Pretorius, Sandra, Methusi, Puthuma and Sliwa, Karen. (2011) Standing at the crossroads between new and historically prevalent heart disease :Effects of migration and socio-economic factors in the Heart of Soweto cohort study. European Heart Journal. 32(4), pp. 492 - 499. https://doi.org/10.1093/eurheartj/ehq439
Genre pedagogy meets e-learning: The LCC project in English Language Education
Mahboob, Ahmar, Humphrey, Sally, Webster, Jonathan, Wong, Eva, Wong, Crusher and Chan, A. (2010) Genre pedagogy meets e-learning: The LCC project in English Language Education. 5th International Symposium on Teaching English at Tertiary Level Hong Kong Polytechnic University. China: Department of English, The Hong Kong Polytechnic University. pp. 23 - 36
Predisposing factors and incidence of newly diagnosed atrial fibrillation in an urban African community : insights from the Heart of Soweto Study
Sliwa, Karen, Carrington, Melinda, Klug, Eric, Opie, Lionel, Lee, Geraldine and Stewart, Simon. (2010) Predisposing factors and incidence of newly diagnosed atrial fibrillation in an urban African community : insights from the Heart of Soweto Study. Heart. 96(23), pp. 1878 - 1882. https://doi.org/10.1136/hrt.2010.206938
Copper(ii)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: Comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments
Lu, J., Gong, D., Choong, Y. S., Xu, H., Chan, Kai, Chen, X., Fitzpatrick, S., Glyn-Jones, S., Zhang, S., Nakamura, T., Ruggiero, K., Obolonkin, V., Poppitt, S. D., Phillips, A. R. J. and Cooper, G. J. S.. (2010) Copper(ii)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: Comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments. Diabetologia. 53(6), pp. 1217 - 1226. https://doi.org/10.1007/s00125-010-1698-8
Bridging the gap in heart failure prevention: Rationale and design of the Nurse-led intervention for Less Chronic Heart Failure (NiL-CHF) Study
Carrington, Melinda J. and Stewart, Simon. (2010) Bridging the gap in heart failure prevention: Rationale and design of the Nurse-led intervention for Less Chronic Heart Failure (NiL-CHF) Study. European Journal of Heart Failure. 12(1), pp. 82 - 88. https://doi.org/10.1093/eurjhf/hfp161
Structured telephone support or telemonitoring programs for patients with chronic heart failure
Inglis, Sally, Clark, Robyn, McAlister, F, Ball, Jocasta, Lewinter, Christian, Cullington, Damien, Stewart, Simon and Cleland, John. (2010) Structured telephone support or telemonitoring programs for patients with chronic heart failure. Cochrane Database of Systematic Reviews. 8, pp. 1 - 144. https://doi.org/10.1002/14651858.CD007228
Pattern of blood pressure in Australian adults : Results from a National Blood Pressure Screening Day of 13,825 adults
Carrington, Melinda, Jennings, Garry L. and Stewart, Simon. (2010) Pattern of blood pressure in Australian adults : Results from a National Blood Pressure Screening Day of 13,825 adults. International Journal of Cardiology. 145(3), pp. 461 - 467. https://doi.org/10.1016/j.ijcard.2009.06.003
Theoretical exploration of the neural bases of behavioural disinhibition, apathy and executive dysfunction in preclinical Alzheimer's disease in people with Down's syndrome: Potential involvement of multiple frontal-subcortical neuronal circuits
Ball, S., Holland, Anne, Watson, P. and Huppert, Felicia. (2010) Theoretical exploration of the neural bases of behavioural disinhibition, apathy and executive dysfunction in preclinical Alzheimer's disease in people with Down's syndrome: Potential involvement of multiple frontal-subcortical neuronal circuits. Journal of Intellectual Disability Research. 54(4), pp. 320 - 336. https://doi.org/10.1111/j.1365-2788.2010.01261.x
Structured telephone support or telemonitoring programs for patients with chronic heart failure
Inglis, Sally, Clark, Robyn, McAlister, F, Ball, Jocasta, Lewinter, Christian, Cullington, Damien, Stewart, Simon and Cleland, John. (2010) Structured telephone support or telemonitoring programs for patients with chronic heart failure. Cochrane Database of Systematic Reviews. 8, pp. 1 - 144. https://doi.org/10.1002/14651858.CD007228.pub2
Incidence and characteristics of newly diagnosed rheumatic heart disease in Urban African adults : insights from the Heart of Soweto Study
Sliwa, Karen, Carrington, Melinda, Mayosi, Bongani, Zigiriadis, Elias and Mvungi, Robert. (2010) Incidence and characteristics of newly diagnosed rheumatic heart disease in Urban African adults : insights from the Heart of Soweto Study. European Heart Journal. 31(6), pp. 719 - 727. https://doi.org/10.1093/eurheartj/ehp530
Predisposing factors and incidence of newly diagnosed atrial fibrillation in an urban African community : insights from the Heart of Soweto Study
Sliwa, Karen, Carrington, Melinda, Klug, Eric, Opie, Lionel, Lee, Geraldine and Stewart, Simon. (2010) Predisposing factors and incidence of newly diagnosed atrial fibrillation in an urban African community : insights from the Heart of Soweto Study. Heart. 96(23), pp. 1878 - 1882. https://doi.org/10.1136/hrt.2010.206938
Cholesterol complacency in Australia: Time to revisit the basics of cardiovascular disease prevention
Carrington, Melinda Jane, Retegan, Claudia, Johnston, Colin I., Jennings, Garry L. and Stewart, Simon. (2009) Cholesterol complacency in Australia: Time to revisit the basics of cardiovascular disease prevention. Journal of Clinical Nursing. 18(5), pp. 678 - 686. https://doi.org/10.1111/j.1365-2702.2008.02507.x
Nature's clocks and human mood: The circadian system modulates reward motivation
Murray, Greg, Nicholas, Christian, Kleiman, Jan, Dwyer, Robyn, Carrington, Melinda, Allen, Nicholas and Trinder, John. (2009) Nature's clocks and human mood: The circadian system modulates reward motivation. Emotion (online version). 9(5), pp. 705 - 716. https://doi.org/10.1037/a0017080
A time bomb of cardiovascular risk factors in South Africa: Results from the Heart of Soweto Study "Heart Awareness Days"
Tibazarwa, Kemi, Ntyintyane, Lucas, Sliwa, Karen, Gernholtz, Trevor, Carrington, Melinda Jane, Wilkinson, David and Stewart, Simon. (2009) A time bomb of cardiovascular risk factors in South Africa: Results from the Heart of Soweto Study "Heart Awareness Days". International Journal of Cardiology. 132(2), pp. 233 - 239. https://doi.org/10.1016/j.ijcard.2007.11.067
Blood pressure and heart rate during continuous experimental sleep fragmentation in health adults
Carrington, Melinda Jane and Trinder, John. (2008) Blood pressure and heart rate during continuous experimental sleep fragmentation in health adults. Sleep. 31(12), pp. 1701 - 1712. https://doi.org/10.1093/sleep/31.12.1701
Older fallers with poor working memory overestimate their postural limits
Liu-Ambrose, Teresa, Ahamed, Yasmin, Graf, Peter, Feldman, Fabio and Robinovitch, Stephen. (2008) Older fallers with poor working memory overestimate their postural limits. Archives of Physical Medicine and Rehabilitation. 89(7), pp. 1335 - 1340. https://doi.org/10.1016/j.apmr.2007.11.052
Otago home-based strength and balance retraining improves executive functioning in older fallers: A randomized controlled trial
Liu-Ambrose, Teresa, Donaldson, Meghan, Ahamed, Yasmin, Graf, Peter, Cook, Wendy, Close, Jacqueline, Lord, Stephen and Khan, Karim. (2008) Otago home-based strength and balance retraining improves executive functioning in older fallers: A randomized controlled trial. Journal of the American Geriatrics Society. 56(10), pp. 1821 - 1830. https://doi.org/10.1111/j.1532-5415.2008.01931.x
Characterising cortical density in the mid-tibia: Intra-individual variation in adolescent girls and boys
Cooper, David M.L., Ahamed, Yasmin, Macdonald, Heather M. and McKay, Heather Anne. (2008) Characterising cortical density in the mid-tibia: Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys
Cooper, David, Ahamed, Yasmin, Macdonald, Heather and McKay, Heather. (2008) Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
The effects on cardiovascular autonomic control of repetitive arousal from sleep
Chaicharn, Jaree, Carrington, Melinda Jane, Trinder, John and Khoo, Michael. (2008) The effects on cardiovascular autonomic control of repetitive arousal from sleep. Sleep. 31(1), pp. 93 - 103. https://doi.org/10.1093/sleep/31.1.93
Is fenofibrate a cost-saving treatment for middle-aged individuals with type ii diabetes? An economic analysis of the FIELD Study
Carrington, Melinda Jane and Stewart, Simon. (2008) Is fenofibrate a cost-saving treatment for middle-aged individuals with type ii diabetes? An economic analysis of the FIELD Study. International Journal of Cardiology. 127(1), pp. 51 - 56. https://doi.org/10.1016/j.ijcard.2007.04.040
Prognostic impact of pulmonary arterial hypertension: A population-based analysis
Carrington, Melinda Jane, Murphy, Niamh F., Strange, Geoff, Peacock, Andrew, McMurray, John J.V. and Stewart, Simon. (2008) Prognostic impact of pulmonary arterial hypertension: A population-based analysis. International Journal of Cardiology. 124(2), pp. 183 - 187. https://doi.org/10.1016/j.ijcard.2006.12.045
The effects on cardiovascular autonomic control of repetitive arousal from sleep
Chaicharn, Jaree, Carrington, Melinda, Trinder, John and Khoo, Michael. (2008) The effects on cardiovascular autonomic control of repetitive arousal from sleep. Sleep (online version). 31(1), pp. 93 - 103. https://doi.org/10.1093/sleep/31.1.93
Otago home-based strength and balance retraining improves executive functioning in older fallers : A randomized controlled trial
Liu-Ambrose, Teresa, Donaldson, Meghan, Ahamed, Yasmin, Graf, Peter, Cook, Wendy, Close, Jacqueline, Lord, Stephen and Khan, Karim. (2008) Otago home-based strength and balance retraining improves executive functioning in older fallers : A randomized controlled trial. Journal of the American Geriatrics Society. 56(10), pp. 1821 - 1830. https://doi.org/10.1111/j.1532-5415.2008.01931.x
Are ECG abnormalities common in black AFricans with heart failure? Results from the Heart of Soweto study
Lee, Geraldine, Carrington, Melinda Jane, Sliwa, Karen and Stewart, Simon. (2008) Are ECG abnormalities common in black AFricans with heart failure? Results from the Heart of Soweto study. South African Heart Journal. 5(1), pp. 4 - 11. https://doi.org/10.24170/5-1-2056
No evidence of an effect of alterations in dietary fatty acids on fasting adiponectin over 3 weeks
Lithander, Fiona E., Keogh, Geraldine F., Wang, Yu, Cooper, G. J. S., Mulvey, Tom B., Chan, Kai, McArdle, Brian H. and Poppitt, S D.. (2008) No evidence of an effect of alterations in dietary fatty acids on fasting adiponectin over 3 weeks. Obesity. 16(3), pp. 592 - 599. https://doi.org/10.1038/oby.2007.97
Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load
Poppitt, S. D., Keogh, Geraldine F., Lithander, Fiona E., Chan, Kai, Wang, Yu, Mulvey, Tom B., McArdle, Brian H. and Cooper, G J. S.. (2008) Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition. 24(4), pp. 322 - 329. https://doi.org/10.1016/j.nut.2007.12.012
Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys
Cooper, David, Ahamed, Yasmin, Macdonald, Heather and McKay, Heather. (2008) Characterising cortical density in the mid-tibia : Intra-individual variation in adolescent girls and boys. British Journal of Sports Medicine. 42(8), pp. 690 - 695. https://doi.org/10.1136/bjsm.2008.049528
A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes
Gong, D., Lu, J., Chen, X., Reddy, S., Crossman, D J., Glyn-Jones, S, Choong, Y-S, Kennedy, J, Barry, B, Zhang, S, Chan, Kai, Ruggiero, K, Phillips, A. R. J. and Cooper, G. J. S.. (2008) A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes. Diabetologia. 51(9), pp. 1741 - 1751. https://doi.org/10.1007/s00125-008-1088-7
Blood pressure and heart rate during continuous experimental sleep fragmentation in health adults
Carrington, Melinda and Trinder, John. (2008) Blood pressure and heart rate during continuous experimental sleep fragmentation in health adults. Sleep (online version). 31(12), pp. 1701 - 1712. https://doi.org/10.1093/sleep/31.12.1701
Older fallers with poor working memory overestimate their postural limits
Liu-Ambrose, Teresa, Ahamed, Yasmin, Graf, Peter, Feldman, Fabio and Robinovitch, Stephen. (2008) Older fallers with poor working memory overestimate their postural limits. Archives of Physical Medicine and Rehabilitation. 89(7), pp. 1335 - 1340. https://doi.org/10.1016/j.apmr.2007.11.052
Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients
Lu, Jun, Chan, Kai, Gamble, Gregory D., Poppitt, S D., Othman, Asma A. and Cooper, G. J. S.. (2007) Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients. Drug Metabolism and Disposition. 35(2), pp. 221 - 227. https://doi.org/10.1124/dmd.106.012922
School-based physical activity does not compromise children's academic performance
Ahamed, Yasmin, MacDonald, Heather, Reed, Katherine, Naylor, Patti-Jean, Liu-Ambrose, Teresa and McKay, Heather. (2007) School-based physical activity does not compromise children's academic performance. Medicine & Science in Sports & Exercise. 39(2), pp. 371 - 376. https://doi.org/10.1249/01.mss.0000241654.45500.8e
School-based physical activity does not compromise children's academic performance
Ahamed, Yasmin, MacDonald, Heather, Reed, Katherine, Naylor, Patti-Jean, Liu-Ambrose, Teresa and McKay, Heather. (2007) School-based physical activity does not compromise children's academic performance. Medicine and Science in Sports and Exercise. 39(2), pp. 371 - 376. https://doi.org/10.1249/01.mss.0000241654.45500.8e
Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS)
Lu, Jun, Chan, Kai, Poppitt, S. D. and Cooper, G J. S.. (2007) Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS). Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 859(1), pp. 62 - 68. https://doi.org/10.1016/j.jchromb.2007.09.001
Effect of high-fat meals and fatty acid saturation on postprandial levels of the hormones ghrelin and leptin in healthy men
Poppitt, S. D., Leahy, F. E., Keogh, G. F., Wang, Y, Mulvey, T B., Stojkovic, M, Chan, Kai, Choong, Y S., McArdle, B H. and Cooper, G. J. S.. (2006) Effect of high-fat meals and fatty acid saturation on postprandial levels of the hormones ghrelin and leptin in healthy men. European Journal of Clinical Nutrition. 60(1), pp. 77 - 84. https://doi.org/10.1038/sj.ejcn.1602270
Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats
Gong, Deming, Lu, Jun, Chen, Xiuyin, Choong, Soon Y., Zhang, Shaoping, Chan, Kai, Glyn-Jones, Sarah, Gamble, Gregory D., Phillips, Anthony R. J. and Cooper, Garth J. S.. (2006) Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats. Molecular Pharmacology. 70(6), pp. 2045 - 2051. https://doi.org/10.1124/mol.106.028605
Demonstratuon of hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation
Cooper, G. J. S., Chan, Kai, Dissanayake, Ajith M., Leahy, Fiona E., Keogh, Geraldine F., Frampton, Chris M., Gamble, Gregory D., Brunton, Dianne H., Baker, John R. and Poppitt, S D.. (2005) Demonstratuon of hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation. Diabetes. 54(5), pp. 1468 - 1476.
Changes in cardiovascular function during the sleep onset period in young adults
Carrington, Melinda Jane, Barbieri, R., Colrain, I. M., Crowley, K. E., Kim, Y. and Trinder, J.. (2005) Changes in cardiovascular function during the sleep onset period in young adults. Journal of Applied Physiology. 98(2), pp. 468 - 476. https://doi.org/10.1152/japplphysiol.00702.2004
Subjective and predicted sleepiness while driving in young adults
Smith, Simon, Carrington, Melinda Jane and Trinder, John. (2005) Subjective and predicted sleepiness while driving in young adults. Accident Analysis and Prevention. 37(6), pp. 1066 - 1073. https://doi.org/10.1016/j.aap.2005.06.008
Regeneration of the heart in diabetes by selective copper chelation
Cooper, G. J. S., Phillips, Anthony R. J., Choong, Soon Y., Leonard, Bridget L., Crossman, David J., Brunton, Dianne H., Saafi, Etuate L., Dissanayake, Ajith M., Cowan, Brett R., Young, Alistair A., Occleshaw, Christopher J., Chan, Kai, Leahy, Fiona E., Keogh, Geraldine F., Gamble, Gregory D., Allen, Grant R., Pope, Adele J., Boyd, Peter D. W., Poppitt, S D., ... Baker, John R.. (2004) Regeneration of the heart in diabetes by selective copper chelation. Diabetes. 53(9), pp. 2501 - 2508.
The influence of sleep onset on the diurnal variation in cardiac activity and cardiac control
Carrington, Melinda Jane, Walsh, Michelle, Stambas, Thalia, Kleiman, Jan and Trinder, John. (2003) The influence of sleep onset on the diurnal variation in cardiac activity and cardiac control. Journal of Sleep Research. 12(3), pp. 213 - 221. https://doi.org/10.1046/j.1365-2869.2003.00364.x
The effects of normal aging on sleep spindle and K-complex production
Crowley, Kate, Trinder, John, Kim, Young, Carrington, Melinda Jane and Colrain, Ian M.. (2002) The effects of normal aging on sleep spindle and K-complex production. Clinical Neurophysiology. 113(10), pp. 1615 - 1622. https://doi.org/10.1016/S1388-2457(02)00237-7
Autonomic activity during human sleep as a function of time and sleep stage
Trinder, John, Kleiman, Jan, Carrington, Melinda, Smith, Simon, Breen, Sibilah, Tan, Nellie and Kim, Young. (2001) Autonomic activity during human sleep as a function of time and sleep stage. Journal of Sleep Research. 10(4), pp. 253 - 264. https://doi.org/10.1046/j.1365-2869.2001.00263.x
Autonomic activity during human sleep as a function of time and sleep stage
Trinder, John, Kleiman, Jan, Carrington, Melinda Jane, Smith, Simon, Breen, Sibilah, Tan, Nellie and Kim, Young. (2001) Autonomic activity during human sleep as a function of time and sleep stage. Journal of Sleep Research. 10(4), pp. 253 - 264. https://doi.org/10.1046/j.1365-2869.2001.00263.x