A systematic review of the spectrum of cardiac arrhythmias in Sub-Saharan Africa

Journal article


Yuyun, Matthew F., Bonny, Aimé, Ng, G. André, Sliwa, Karen, Kengne, Andre Pascal, Chin, Ashley, Mocumbi, Ana Olga, Ngantcha, Marcus, Ajijola, Olujimi A. and Bukhman, Gene. (2020) A systematic review of the spectrum of cardiac arrhythmias in Sub-Saharan Africa. Global Heart. 15(1), pp. 1-30. https://doi.org/10.5334/gh.808
AuthorsYuyun, Matthew F., Bonny, Aimé, Ng, G. André, Sliwa, Karen, Kengne, Andre Pascal, Chin, Ashley, Mocumbi, Ana Olga, Ngantcha, Marcus, Ajijola, Olujimi A. and Bukhman, Gene
Abstract

Major structural cardiovascular diseases are associated with cardiac arrhythmias, but their full spectrum remains unknown in sub-Saharan Africa (SSA), which we addressed in this systematic review. Atrial fibrillation/atrial flutter (AF/AFL) prevalence is 16–22% in heart failure, 10–28% in rheumatic heart disease, 3–7% in cardiology admissions, but <1% in the general population. Use of oral anticoagulation is heterogenous (9–79%) across SSA. The epidemiology of sudden cardiac arrest/death is less characterized in SSA. Cardiopulmonary resuscitation is challenging, owing to low awareness and lack of equipment for life-support. About 18% of SSA countries have no cardiac implantable electronic devices services, leaving hundreds of millions of people without any access to treatment for advanced bradyarrhythmias, and implant rates are more than 200-fold lower than in the western world. Management of tachyarrhythmias is largely non-invasive (about 80% AF/AFL via rate-controlled strategy only), as electrophysiological study and catheter ablation centers are almost non-existent in most countries.

Keywordsatrial arrhythmias; supraventricular tachycardia; sudden cardiac death; ventricular arrhythmias; pacemaker; defibrillator; sub-Saharan Africa
Year2020
JournalGlobal Heart
Journal citation15 (1), pp. 1-30
PublisherElsevier BV
ISSN2211-8160
Digital Object Identifier (DOI)https://doi.org/10.5334/gh.808
Scopus EID2-s2.0-85090154214
Open accessPublished as ‘gold’ (paid) open access
Research or scholarlyResearch
Page range1-30
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online08 May 2020
Publication process dates
Accepted18 Apr 2020
Deposited30 Mar 2021
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