Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review
Journal article
Jean Nyakayiru, Luc Van Loon and Lex B. Verdijk. (2020). Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review. Free Radical Biology & Medicine. 152, pp. 295-300. https://doi.org/10.1016/j.freeradbiomed.2020.03.025
Authors | Jean Nyakayiru, Luc Van Loon and Lex B. Verdijk |
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Abstract | Extensive research performed over the past 10 years has resulted in dietary nitrate being considered a nutritional supplement that can improve exercise performance. However, there is still limited insight in the metabolic fate of dietary nitrate following the appearance of nitrate and nitrite in the circulation. Recent observations in humans suggest the storage of nitrate in skeletal muscle tissue. This short review discusses the possibility of nitrate being stored and utilized in human skeletal muscle tissue, and why confirming this may increase our understanding of how the nitrate-nitrite-NO pathway improves exercise performance. Further insight in skeletal muscle nitrate storage and metabolism may provide answers to current gaps in knowledge, such as the ergogenic benefit of acute vs multiday dietary nitrate supplementation, as well as the suggested muscle fiber-type specific effects on exercise performance. In this mini-review, specific questions that need further exploration are also discussed. |
Keywords | nitric oxide; nitrite; ergogenic aid; beetroot juice |
Year | 2020 |
Journal | Free Radical Biology & Medicine |
Journal citation | 152, pp. 295-300 |
Publisher | Elsevier Inc. |
ISSN | 0891-5849 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.freeradbiomed.2020.03.025 |
Scopus EID | 2-s2.0-85082743780 |
Open access | Published as ‘gold’ (paid) open access |
Publisher's version | License File Access Level Open |
Publication process dates | |
Deposited | 27 Apr 2021 |
https://acuresearchbank.acu.edu.au/item/8vy54/could-intramuscular-storage-of-dietary-nitrate-contribute-to-its-ergogenic-effect-a-mini-review
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Publisher's version
OA_Nyakayiru_2020_Could_intramuscular_storage_of_dietary_nitrate.pdf | |
License: CC BY 4.0 | |
File access level: Open |
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