Improved partial volume correction for single inversion time arterial spin labeling data
Journal article
Liang, Xiaoyun, Connelly, Alan and Calamante, Fernando. (2013). Improved partial volume correction for single inversion time arterial spin labeling data. Magnetic Resonance in Medicine. 69(2), pp. 531-537. https://doi.org/10.1002/mrm.24279
Authors | Liang, Xiaoyun, Connelly, Alan and Calamante, Fernando |
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Abstract | Arterial spin labeling has relatively low spatial resolution, which affects cerebral blood flow measurements by partial volume effect occurring at tissue interfaces, e.g., between gray matter, white matter, and cerebrospinal fluid. This can be an important source of cerebral blood flow quantification error. To correct for partial volume effect in arterial spin labeling, a linear regression method was recently proposed. Because this method assumes that tissue magnetization and cerebral blood flow are constant over an n2 × 1 regression kernel, an inherent spatial blurring is introduced. In this study, a modified least trimmed squares algorithm is proposed for partial volume effect correction. It is demonstrated using simulations that the modified least trimmed square method can correct for partial volume effect and produce less blurring than the linear regression method. This is achieved without either acquiring additional datasets or increasing the computation burden. These capabilities were further demonstrated in vivo. The modified least trimmed square method should, therefore, play an important role in arterial spin labeling studies. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc. |
Keywords | arterial spin labeling; perfusion MRI; partial volume correction; linear trimmed squares |
Year | 2013 |
Journal | Magnetic Resonance in Medicine |
Journal citation | 69 (2), pp. 531-537 |
Publisher | John Wiley & Sons |
ISSN | 0740-3194 |
Digital Object Identifier (DOI) | https://doi.org/10.1002/mrm.24279 |
Scopus EID | 2-s2.0-84872938475 |
Research or scholarly | Research |
Page range | 531-537 |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 23 Apr 2012 |
Publication process dates | |
Accepted | 09 Mar 2012 |
Deposited | 27 Apr 2021 |
https://acuresearchbank.acu.edu.au/item/8vy61/improved-partial-volume-correction-for-single-inversion-time-arterial-spin-labeling-data
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