The effects of beta-alanine supplementation on physical working capacity at heart rate threshold

Journal article


Smith-Ryan, Abbie E., Woessner, Mary N., Melvin, Malia N., Wingfield, Hailee L. and Hackney, Anthony C.. (2014). The effects of beta-alanine supplementation on physical working capacity at heart rate threshold. Clinical Physiology and Functional Imaging. 34(5), pp. 397-404. https://doi.org/10.1111/cpf.12111
AuthorsSmith-Ryan, Abbie E., Woessner, Mary N., Melvin, Malia N., Wingfield, Hailee L. and Hackney, Anthony C.
Abstract

Beta‐alanine (BA) supplementation has been shown to delay neuromuscular fatigue as a result of increased muscle carnosine concentrations. Carnosine has also been found in brain and cardiac tissue. The physical working capacity test at heart rate threshold (PWCHRT) is a global estimate of the onset of fatigue during exercise, influenced by central and peripheral factors. The purpose of this study was to determine the effects of 28 days of BA supplementation on the PWCHRT. Thirty subjects (mean ± SD; age: 21·0 ± 2·1 years; body mass: 72·7 ± 14·5 kg; height: 170·1 ± 7·9 cm) were randomly assigned to BA (n = 15) or placebo (PL, n = 15) groups. Testing included eight to nine total visits: an enrolment day, physical screening, peak oxygen consumption (V·O2peak) and two PWCHRT assessments over 4 days. Significant differences existed between BA and PL for PWCHRT (P = 0·001; mean∆: BA∆ = +24·2 watts, PL∆ = +11·2 watts), but not for V·O2peak (P = 0·222), time to exhaustion (TTE; P = 0·562) or ventilatory threshold (VT; P = 0·134). Results suggest that BA may increase heart rate training threshold. These results, in combination with one previous study reporting a potential effect of BA on HR, suggest that future studies should evaluate both central and peripheral aspects of fatigue with BA intake.

Keywordsaerobic exercise; carnosine; clinical evaluation; ergogenic aid; pH
Year2014
JournalClinical Physiology and Functional Imaging
Journal citation34 (5), pp. 397-404
PublisherWiley-Blackwell Publishing Ltd.
ISSN1475-0961
Digital Object Identifier (DOI)https://doi.org/10.1111/cpf.12111
Scopus EID2-s2.0-84908356016
Research or scholarlyResearch
Page range397-404
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online05 Dec 2013
Publication process dates
Accepted15 Nov 2013
Deposited10 May 2021
Permalink -

https://acuresearchbank.acu.edu.au/item/8vzx4/the-effects-of-beta-alanine-supplementation-on-physical-working-capacity-at-heart-rate-threshold

Restricted files

Publisher's version

  • 63
    total views
  • 0
    total downloads
  • 1
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Eating disorders are associated with increased risk of fall injury and fracture in Swedish men and women
Axelsson, K. F., Woessner, M. N., Litsne, H., Wheeler, M., Flehr, A., King, A. J., Kalén, M., Vandenput, L. and Lorentzon, M.. (2022). Eating disorders are associated with increased risk of fall injury and fracture in Swedish men and women. Osteoporosis International. 33(6), pp. 1347-1355. https://doi.org/10.1007/s00198-022-06312-2
Higher bone remodeling biomarkers are related to a higher muscle function in older adults : Effects of acute exercise
Smith, Cassandra, Hiam, Danielle, Tacey, Alexander, Lin, Xuzhu, Woessner, Mary, Zarekookandeh, Navabeh, Garnham, Andrew Peter, Chubb, Paul, Lewis, Joshua, Sim, Marc, Herrmann, Markus, Duque, Gustavo and Levinger, Itamar. (2022). Higher bone remodeling biomarkers are related to a higher muscle function in older adults : Effects of acute exercise. Bone. 165, pp. 1-10. https://doi.org/10.1016/j.bone.2022.116545
The Effects of Acute High-Intensity Interval Exercise and Hyperinsulinemic-Euglycemic Clamp on Osteoglycin Levels in Young and Middle-Aged Men
Bauer, Carlie, Tacey, Alexander, Garnham, Andrew Peter, Smith, Cassandra, Woessner, Mary, Lin, Xuzhu, Zarekookandeh, Navabeh, Hare, David, Lewis, Joshua, Parker, Lewan and Levinger, Itamar. (2022). The Effects of Acute High-Intensity Interval Exercise and Hyperinsulinemic-Euglycemic Clamp on Osteoglycin Levels in Young and Middle-Aged Men. JBMR Plus. 6(11), pp. 1-6. https://doi.org/10.1002/jbm4.10667
Effects of inorganic nitrate supplementation on cardiovascular function and exercise tolerance in heart failure
Ferguson, Scott K., Woessner, Mary N., Holmes, Michael J., Belbis, Michael D., Carlström, Mattias, Weitzberg, Eddie, Allen, Jason D. and Hirai, Daniel M.. (2021). Effects of inorganic nitrate supplementation on cardiovascular function and exercise tolerance in heart failure. Journal of Applied Physiology. 130(4), pp. 914-922. https://doi.org/10.1152/JAPPLPHYSIOL.00780.2020
Effects of Dietary Inorganic Nitrate Supplementation on Exercise Performance in Patients With Heart Failure: Protocol for a Randomized, Placebo-Controlled, Cross-Over Trial
Mary N Woessner, Itamar Levinger, Christopher J Neil, Cassandra Smith and Jason D Allen. (2018). Effects of Dietary Inorganic Nitrate Supplementation on Exercise Performance in Patients With Heart Failure: Protocol for a Randomized, Placebo-Controlled, Cross-Over Trial. JMIR Research Protocols. 7(4), pp. 1-12. https://doi.org/10.2196/resprot.8865
Dietary nitrate supplementation in cardiovascular health: an ergogenic aid or exercise therapeutic?
Mary N Woessner, Luke C McIlvenna, Joaquin Ortiz de Zevallos, Christopher J Neil and Jason D Allen. (2018). Dietary nitrate supplementation in cardiovascular health: an ergogenic aid or exercise therapeutic? American Journal of Physiology: Heart and Circulatory Physiology. 314(2), pp. 195-212. https://doi.org/10.1152/ajpheart.00414.2017
Beet the Best? Dietary inorganic nitrate to augment exercise training in lower extremity peripheral artery disease with intermittent claudication
Woessner, Mary, VanBruggen, Mitch D., Pieper, Carl F., Sloane, Richard, Kraus, William E., Gow, Andrew J. and Allen, Jason D.. (2018). Beet the Best? Dietary inorganic nitrate to augment exercise training in lower extremity peripheral artery disease with intermittent claudication. Circulation Research. 123(6), pp. 654 - 659. https://doi.org/10.1161/CIRCRESAHA.118.313131
Combined Dietary Nitrate and Exercise Intervention in Peripheral Artery Disease: Protocol Rationale and Design
Mary N Woessner, Mitch D VanBruggen, Carl F Pieper, Erin K O'Reilly, William E. Kraus and Jason D Allen. (2017). Combined Dietary Nitrate and Exercise Intervention in Peripheral Artery Disease: Protocol Rationale and Design. JMIR Research Protocols. 6(10), pp. 1-12. https://doi.org/10.2196/resprot.7596
Reproducibility and validity of a-mode ultrasound for body composition measurement and classification in overweight and obese men and women
Smith-Ryan, Abbie E., Fultz, Sarah N., Melvin, Malia N., Wingfield, Hailee L. and Woessner, Mary N.. (2014). Reproducibility and validity of a-mode ultrasound for body composition measurement and classification in overweight and obese men and women. PLoS ONE. 9(3), pp. 1-8. https://doi.org/10.1371/journal.pone.0091750
Body composition assessment in overweight women : Validation of air displacement plethysmography
Wingfield, Hailee L., Smith-Ryan, Abbie E., Woessner, Mary N., Melvin, Malia N., Fultz, Sarah N. and Graff, Rachel M.. (2014). Body composition assessment in overweight women : Validation of air displacement plethysmography. Clinical Physiology and Functional Imaging. 34(1), pp. 72-76. https://doi.org/10.1111/cpf.12067