Mild depression predicts long-term mortality after acute myocardial infarction : A 25-year follow-up

Journal article


Worcester, Marian U., Goble, Alan J., Elliott, Peter C., Froelicher, Erika S., Murphy, Barbara M., Beauchamp, Alison J., Jelinek, Michael V. and Hare, David L.. (2019). Mild depression predicts long-term mortality after acute myocardial infarction : A 25-year follow-up. Heart, Lung and Circulation. 28, pp. 1812-1818. https://doi.org/10.1016/j.hlc.2018.11.013
AuthorsWorcester, Marian U., Goble, Alan J., Elliott, Peter C., Froelicher, Erika S., Murphy, Barbara M., Beauchamp, Alison J., Jelinek, Michael V. and Hare, David L.
Abstract

Background
Past studies have found that depression is an independent predictor of death in patients after acute myocardial infarction (AMI). Our aim was to investigate whether the adverse effect upon mortality of depression, including mild levels, persisted up to 25 years.

Methods
We used an historical design to study patients who had been consecutively admitted to hospital after transmural AMI during the 1980s and enrolled in an exercise training trial. The Beck Depression Inventory (BDI) was administered to 188 patients in the third week after hospital admission. Scores were trichotomised and classified as low (0–5), mild (6–9) or moderate to severe (≥10) depression. The Australian National Death Index was used to determine mortality status. Cox proportional-hazards modelling was undertaken to determine the relationship between the trichotomised BDI-I scores and all-cause mortality over five time periods up to 25 years.

Results
The mean age of patients was 54.15 years. One hundred fourteen (114) (60.4%) had low or no depression, 47 (25.2%) mild depression and 27 (14.3%) moderate to severe depression. The mortality status of 185 (98.4%) patients was established. Depression was a significant predictor of death, independently of age and severity of myocardial infarction, at 5, 10 and 15 years but not at 20 or 25 years. Patients with mild depression had greater mortality than those with low or moderate to severe depression.

Conclusions
Early identification of depression, including milder levels, is important since patients remain at increased risk for many years. They require ongoing monitoring and appropriate treatment.

Keywordsdepression; long-term mortality; cardiovascular diseases prevention; acute coronary syndrome; cardiac rehabilitation; secondary prevention
Year2019
JournalHeart, Lung and Circulation
Journal citation28, pp. 1812-1818
PublisherElsevier Australia
ISSN1443-9506
Digital Object Identifier (DOI)https://doi.org/10.1016/j.hlc.2018.11.013
Scopus EID2-s2.0-85061175157
Research or scholarlyResearch
Page range1812-1818
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online05 Dec 2018
Publication process dates
Accepted26 Nov 2018
Deposited03 Jun 2021
Permalink -

https://acuresearchbank.acu.edu.au/item/8w268/mild-depression-predicts-long-term-mortality-after-acute-myocardial-infarction-a-25-year-follow-up

Restricted files

Publisher's version

  • 6
    total views
  • 0
    total downloads
  • 0
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Prediction of incident heart failure by serum amino-terminal pro-B-type natriuretic peptide level in a community-based cohort
Campbell, Duncan J., Gong, Fei Fei, Jelinek, Michael V., Castro, Julian M., Coller, Jennifer M., McGrady, Michele, Boffa, Umberto, Shiel, Louise, Wang, Bing H., Liew, Danny, Wolfe, Rory, Stewart, Simon, Owen, Alice J., Krum, Henry, Reid, Christopher M. and Prior, David L.. (2019). Prediction of incident heart failure by serum amino-terminal pro-B-type natriuretic peptide level in a community-based cohort. European Journal of Heart Failure. 21, pp. 449-459. https://doi.org/10.1002/ejhf.1381
Implications of Cardio-Respiratory Fitness on the Performance of Exercise Tests
Michael Jelinek and Kenneth Hossack. (2019). Implications of Cardio-Respiratory Fitness on the Performance of Exercise Tests. Heart, Lung and Circulation. 28(4), pp. 64-66. https://doi.org/10.1016/j.hlc.2018.07.015
Effect of aspirin on cardiovascular events and bleeding in the healthy elderly
McNeil, John J., Wolfe, Rory, Woods, Robyn L., Tonkin, Andrew M., Donnan, Geoffrey A., Nelson, Mark R., Reid, Christopher M., Lockery, Jessica E., Kirpach, Brenda, Storey, Elsdon, Shah, Raj C., Margolis, Karen L., Ernst, Michael E., Abhayaratna, Walter P., Stocks, Nigel, Fitzgerald, Sharyn M., Orchard, Suzanne G., Trevaks, Ruth E., Beilin, Lawrence J., ... Murray, Anne M.. (2018). Effect of aspirin on cardiovascular events and bleeding in the healthy elderly. New England Journal of Medicine. 379(16), pp. 1509-1518. https://doi.org/10.1056/NEJMoa1805819
Coaching Patients Saves Lives and Money
Joshua Byrnes, Thomas Elliott, Margarite Vale, Michael Jelinek and Paul Scuffham. (2018). Coaching Patients Saves Lives and Money. American Journal of Medicine. 131(4), pp. 415-422. https://doi.org/10.1016/j.amjmed.2017.10.019
Risk factors for incident heart failure with preserved or reduced ejection fraction, and valvular heart failure, in a community-based cohort
Gong, Fei Fei, Jelinek, Michael, Castro, Julian M., Coller, Jennifer M., McGrady, Michele, Boffa, Umberto, Shiel, Louise, Liew, Danny, Wolfe, R., Stewart, Simon, Owen, Alice J., Krum, Henry, Reid, Christopher, Prior, David and Campbell, Duncan J.. (2018). Risk factors for incident heart failure with preserved or reduced ejection fraction, and valvular heart failure, in a community-based cohort. Open Heart. 5(2), pp. 1 - 11. https://doi.org/10.1136/openhrt-2018-000782
Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring
Christian R. Hamilton-Craig, Clara Chow, John F. Younger, Michael Jelinek, Jonathan Chan and Gary Y. H. Liew. (2017). Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring. Medical Journal of Australia. 207(8), pp. 357-361. https://doi.org/10.5694/mja16.01134
SMARTphone-based, early cardiac REHABilitation in patients with acute coronary syndromes [SMART-REHAB Trial]: A randomized controlled trial protocol
Yudi, Matias B., Clark, David J., Tsang, David, Jelinek, Michael, Kalten, Katie, Joshi, Subodh, Phan, Khoa, Nasis, Arthur, Amerena, John, Arunothayaraj, Sandeep, Reid, Chris and Farouque, Omar. (2016). SMARTphone-based, early cardiac REHABilitation in patients with acute coronary syndromes [SMART-REHAB Trial]: A randomized controlled trial protocol. BMC Cardiovascular Disorders. 16(170), pp. 1 - 8. https://doi.org/10.1186/s12872-016-0356-6
Improving access and equity in reducing cardiovascular risk : The Queensland Health Model
Ski, Chantal, Vale, Margarite, Bennett, Gary, Chalmers, Victoria, McFarlane, Kim, Jelinek, Michael, Scott, Ian and Thompson, David. (2015). Improving access and equity in reducing cardiovascular risk : The Queensland Health Model. Medical Journal of Australia. 202(3), pp. 148 - 152. https://doi.org/10.5694/mja14.00575
Reversing social disadvantage in secondary prevention of coronary heart disease
Jelinek, Michael, Santamaria, John, Best, James, Thompson, David R., Tonkin, Andrew and Vale, Margarite. (2014). Reversing social disadvantage in secondary prevention of coronary heart disease. International Journal of Cardiology. 171(3), pp. 346 - 350. https://doi.org/10.1016/j.ijcard.2013.12.022
'FIT FOR PURPOSE'. The COACH program improves lifestyle and biomedical cardiac risk factors
Jelinek, Michael, Santamaria, John, Thompson, David and Vale, Margarite. (2012). 'FIT FOR PURPOSE'. The COACH program improves lifestyle and biomedical cardiac risk factors. Heart. 98(21), pp. 1608 - 1608. https://doi.org/10.1136/heartjnl-2012-302723
Reconciling systematic reviews of exercise-based cardiac rehabilitation and secondary prevention programmes for coronary heart disease
Jelinek, Michael, Clark, Alexander, Oldridge, Neil, Briffa, Thomas and Thompson, David Robert. (2011). Reconciling systematic reviews of exercise-based cardiac rehabilitation and secondary prevention programmes for coronary heart disease. European Journal of Cardiovascular Prevention & Rehabilitation. 18(2), pp. 147 - 149. https://doi.org/10.1177/1741826710389388
Screening for depression in coronary heart disease: The perfect Hegelian dialectic? A short commentary on ''Beyond the blues: The need for integrated care pathways''
Jelinek, Michael. (2011). Screening for depression in coronary heart disease: The perfect Hegelian dialectic? A short commentary on ''Beyond the blues: The need for integrated care pathways''. European Journal of Cardiovascular Prevention & Rehabilitation. 18(2), pp. 222 - 223. https://doi.org/10.1177/1741826710389411