The impact of intrathecal baclofen therapy on health-related quality of life for children with marked hypertonia

Journal article

Stewart, Kirsty, Copeland, Lisa and Lewis, Jennifer. (2020). The impact of intrathecal baclofen therapy on health-related quality of life for children with marked hypertonia. Developmental Neurorehabilitation. 23(8), pp. 542-547. https://doi.org/10.1080/17518423.2020.1753841
AuthorsStewart, Kirsty, Copeland, Lisa and Lewis, Jennifer
Abstract

Purpose: To investigate the effects of intrathecal baclofen therapy (ITB) on health-related quality of life for children with cerebral palsy and neurological conditions.

Method: This study is part of a longitudinal, multicentre audit. The primary outcome measure, the Caregiver Priorities and Child Health Index of Life with Disabilities, was completed at baseline, 6 and 12 months post ITB implant.

Results: Forty subjects with cerebral palsy and other neurological conditions demonstrated significant improvement in aspects of health-related quality of life following ITB therapy, mean change 42.3 (SD 14.9) at baseline to 53.3 (SD 14.7) at 12 months (p< .001).

Conclusion: Evidence to demonstrate the utility of ITB in pediatric populations beyond spasticity and dystonia reduction is limited. Our findings suggest that ITB improves aspects of quality of life, comfort, and ease of caregiving in children with cerebral palsy and other neurological conditions.

Keywordsintrathecal baclofen; cerebral palsy; spasticity; dystonia; quality of life
Year2020
JournalDevelopmental Neurorehabilitation
Journal citation23 (8), pp. 542-547
PublisherTaylor & Francis
ISSN1751-8423
Digital Object Identifier (DOI)https://doi.org/10.1080/17518423.2020.1753841
Scopus EID2-s2.0-85084255200
Research or scholarlyResearch
Page range542-547
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online27 Apr 2020
Publication process dates
Accepted02 Apr 2020
Deposited15 Jun 2021
Supplemental file
License
All rights reserved
File Access Level
Controlled
Additional information

Authored on behalf of the Australian Paediatric ITB Research Group.

Permalink -

https://acuresearchbank.acu.edu.au/item/8w3xx/the-impact-of-intrathecal-baclofen-therapy-on-health-related-quality-of-life-for-children-with-marked-hypertonia

Log in to edit

Restricted files

Publisher's version

Supplemental file

  • 61
    total views
  • 0
    total downloads
  • 1
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Current Australian clinical practice in use of botulinum toxin-A to manage paediatric hypertonicity
O'Flaherty, Stephen J and Stewart, Kirsty. (2021). Current Australian clinical practice in use of botulinum toxin-A to manage paediatric hypertonicity. Journal of Paediatrics and Child Health. 57(10), pp. 1662-1665. https://doi.org/10.1111/jpc.15589
The Dyskinetic Cerebral Palsy Functional Impact Scale : Development and validation of a new tool
Stewart, Kirsty, Lewis, Jennifer, Wallen, Margaret, Bear, Natasha and Harvey, Adrienne. (2021). The Dyskinetic Cerebral Palsy Functional Impact Scale : Development and validation of a new tool. Developmental Medicine and Child Neurology. 63(12), pp. 1469-1475. https://doi.org/10.1111/dmcn.14960
Implementing accurate identification and measurement of dyskinesia in cerebral palsy into clinical practice : A knowledge translation study
Stewart, Kirsty, de Vries, Tessa and Harvey, Adrienne. (2019). Implementing accurate identification and measurement of dyskinesia in cerebral palsy into clinical practice : A knowledge translation study. Journal of Paediatrics and Child Health. 55(11), pp. 1351-1356. https://doi.org/10.1111/jpc.14420
Intrathecal baclofen therapy in children : An analysis of individualized goals
Liew, Peck Yee, Stewart, Kirsty, Khan, Debra, Arnup, Sarah Jane and Scheinberg, Adam. (2018). Intrathecal baclofen therapy in children : An analysis of individualized goals. 60(4), pp. 367-373. https://doi.org/10.1111/dmcn.13660
Identification, classification and assessment of dyskinesia in children with cerebral palsy : A survey of clinicians
Stewart, Kirsty, Tavender, Emma, Rice, James and Harvey, Adrienne. (2018). Identification, classification and assessment of dyskinesia in children with cerebral palsy : A survey of clinicians. Journal of Paediatrics and Child Health. 54(4), pp. 432-438. https://doi.org/10.1111/jpc.13749
Intrathecal baclofen therapy in paediatrics : A study protocol for an Australian multicentre, 10-year prospective audit
Stewart, Kirsty, Hutana, Gavin and Kentish, Megan. (2017). Intrathecal baclofen therapy in paediatrics : A study protocol for an Australian multicentre, 10-year prospective audit. BMJ Open. 7(6), p. Article e015863. https://doi.org/10.1136/bmjopen-2017-015863
Using family and staff experiences of a botulinum toxin-A service to improve service quality
Burton, K. L. O., Bau, K., Lewis, J., Aroyan, K. R., Botha, B., Botman, A. G. M., Stewart, K., Waugh, M. C. A. and Paget, S. P.. (2017). Using family and staff experiences of a botulinum toxin-A service to improve service quality. Child: Care, Health and Development. 43(6), pp. 847-853. https://doi.org/10.1111/cch.12500
A systematic review of scales to measure dystonia and choreoathetosis in children with dyskinetic cerebral palsy
Stewart, Kirsty, Harvey, Adrienne and Johnston, Leanne M.. (2017). A systematic review of scales to measure dystonia and choreoathetosis in children with dyskinetic cerebral palsy. Developmental Medicine and Child Neurology. 59(8), pp. 786-795. https://doi.org/10.1111/dmcn.13452
Grading and quantification of upper extremity function in children with spasticity
Wallen, Margaret and Stewart, Kirsty. (2016). Grading and quantification of upper extremity function in children with spasticity. Seminars in Plastic Surgery. 30(1), pp. 5 - 13. https://doi.org/10.1055/s-0035-1571257
Upper limb function in everyday life of children with cerebral palsy: Description and review of parent report measures
Wallen, Margaret and Stewart, Kirsty. (2015). Upper limb function in everyday life of children with cerebral palsy: Description and review of parent report measures. Disability and Rehabilitation. 37(15), pp. 1353 - 1361. https://doi.org/10.3109/09638288.2014.963704