The mediating role of KITLG DNA methylation in the association between childhood adversity and cortisol stress reactivity does not replicate in monocytes

Journal article

Frach, Leonard, Tierling, Sascha, Schwaiger, Marion, Moser, Dirk, Heinrichs, Markus, Hengstler, Jan G., Walter, Jörn and Kumsta, Robert. (2020). The mediating role of KITLG DNA methylation in the association between childhood adversity and cortisol stress reactivity does not replicate in monocytes. Psychoneuroendocrinology. 116, p. 104653. https://doi.org/10.1016/j.psyneuen.2020.104653
AuthorsFrach, Leonard, Tierling, Sascha, Schwaiger, Marion, Moser, Dirk, Heinrichs, Markus, Hengstler, Jan G., Walter, Jörn and Kumsta, Robert
Abstract

Adverse childhood experiences such as maltreatment or neglect are associated with mental health problems in adulthood. Changes in the regulation of the psychological and physiological stress reaction, mediated via epigenetic modifications, are discussed as potential mechanisms. This study aimed to replicate the role of DNA methylation of the KITLG gene in mediating the association between childhood adversity and stress-induced cortisol reactivity in a sample of adults reporting childhood adversity and a matched control group (N = 60). DNA was extracted from purified CD14+ monocytes and genome-wide DNA methylation was assessed with the 450k BeadChip for targeted replication and exploratory analyses. As previously reported, childhood adversity was associated with significantly lower cortisol reactivity to stress. We could neither replicate the association between KITLG DNA methylation and cortisol stress reactivity nor the association with childhood adversity. Moreover, DNA methylation of the target CpG (cg27512205) was not associated with KITLG mRNA expression in monocytes. Exploratory analyses of array-wide DNA methylation patterns showed no significant results for individual sites after correction for multiple testing – neither in association with childhood trauma nor with adult cortisol stress reactivity. The analysis of differentially methylated regions (DMRs) revealed two significant regions which both mapped to non-coding genes in the association with cortisol stress reactivity.

The mediating role of DNA methylation of the KITLG locus in the association between childhood adversity and cortisol stress reactivity could not be replicated in monocytes. In addition to differences in investigated tissue, reasons for non-replication might include differences between samples in age, ethnicity, trauma severity, and cortisol reactivity.

KeywordsDNA methylation; childhood adversity; EWAS; stress; TSST; replication
Year2020
JournalPsychoneuroendocrinology
Journal citation116, p. 104653
PublisherElsevier Ltd
ISSN0306-4530
Digital Object Identifier (DOI)https://doi.org/10.1016/j.psyneuen.2020.104653
Scopus EID2-s2.0-85081904246
Research or scholarlyResearch
Page range1-7
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online20 Mar 2020
Publication process dates
Accepted09 Mar 2020
Deposited15 Jul 2021
Permalink -

https://acuresearchbank.acu.edu.au/item/8w5zy/the-mediating-role-of-kitlg-dna-methylation-in-the-association-between-childhood-adversity-and-cortisol-stress-reactivity-does-not-replicate-in-monocytes

Log in to edit

Restricted files

Publisher's version

  • 97
    total views
  • 0
    total downloads
  • 3
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Concordance in salivary cortisol and subjective anxiety to the trier social stress test in social anxiety disorder
Grace, Caitlin, Heinrichs, Markus, Koval, Peter, Gorelik, Alexandra, von Dawans, Bernadette, Terrett, Gill, Rendell, Peter and Labuschagne, Izelle. (2022). Concordance in salivary cortisol and subjective anxiety to the trier social stress test in social anxiety disorder. Biological Psychology. 175, p. Article 108444. https://doi.org/10.1016/j.biopsycho.2022.108444
Resting-state neuroimaging in social anxiety disorder : A systematic review
Mizzi, Simone, Pedersen, Mangor, Lorenzetti, Valentina, Heinrichs, Markus and Labuschagne, Izelle. (2022). Resting-state neuroimaging in social anxiety disorder : A systematic review. Molecular Psychiatry. 27(1), pp. 164-179. https://doi.org/10.1038/s41380-021-01154-6
The effect of attachment security priming and oxytocin on physiological responses to trauma films and subsequent intrusions
Karl, Anke, Carnelley, Katherine B., Arikan, Gizem, Baldwin, David S., Heinrichs, Markus and Stopa, Lusia. (2021). The effect of attachment security priming and oxytocin on physiological responses to trauma films and subsequent intrusions. Behaviour Research and Therapy. 141, p. Article 103845. https://doi.org/10.1016/j.brat.2021.103845
Evaluation of an eye tracking setup for studying visual attention in face-to-face conversations
Vehlen, Antonia, Spenthof, Ines, Tönsing, Daniel, Heinrichs, Markus and Domes, Gregor. (2021). Evaluation of an eye tracking setup for studying visual attention in face-to-face conversations. Scientific Reports. 11(1), pp. 1-16. https://doi.org/10.1038/s41598-021-81987-x
Oxytocin receptor gene DNA methylation : A biomarker of treatment response in obsessive-compulsive disorder?
Schiele, M. A., Thiel, C., Kollert, L., Fürst, L., Putschin, L., Kehle, R., Hauke, W., Mahr, M., Reinhold, E., Gottschalk, M. G., Heinrichs, M., Zaudig, M., Berberich, G. and Domschke, K.. (2020). Oxytocin receptor gene DNA methylation : A biomarker of treatment response in obsessive-compulsive disorder? Psychotherapy and Psychosomatics. 90(1), pp. 57-63. https://doi.org/10.1159/000509910
Temporal dynamics of resting EEG networks are associated with prosociality
Schiller, Bastian, Kleinert, Tobias, Teige-Mocigemba, Sarah, Klauer, Karl Christoph and Heinrichs, Markus. (2020). Temporal dynamics of resting EEG networks are associated with prosociality. Scientific Reports. 10(1), p. 13066. https://doi.org/10.1038/s41598-020-69999-5
The Trust Game for Couples (TGC) : A new standardized paradigm to assess trust in romantic relationships
Kleinert, Tobias, Schiller, Bastian, Fischbacher, Urs, Grigutsch, Laura-Anne, Koranyi, Nicolas, Rothermund, Klaus and Heinrichs, Markus. (2020). The Trust Game for Couples (TGC) : A new standardized paradigm to assess trust in romantic relationships. PLoS ONE. 15(3), p. e0230776. https://doi.org/10.1371/journal.pone.0230776
Oxytocin and positive couple interaction affect the perception of wound pain in everyday life
Pfeifer, Ann-Christin, Schroeder-Pfeifer, Paul, Schneider, Ekaterina, Schick, Maren, Heinrichs, Markus, Bodenmann, Guy, Ehlert, Ulrike, Herpertz, Sabine C., Läuchli, Severin, Eckstein, Monika and Ditzen, Beate. (2020). Oxytocin and positive couple interaction affect the perception of wound pain in everyday life. Molecular Pain. 16, pp. 1-10. https://doi.org/10.1177/1744806920918692
Oxytocin changes behavior and spatio-temporal brain dynamics underlying inter-group conflict in humans
Schiller, Bastian, Domes, Gregor and Heinrichs, Markus. (2020). Oxytocin changes behavior and spatio-temporal brain dynamics underlying inter-group conflict in humans. European Neuropsychopharmacology. 31, pp. 119-130. https://doi.org/10.1016/j.euroneuro.2019.12.109
Glucocorticoids and cortical decoding in the phobic brain
Schwab, Simon, Federspiel, Andrea, Morishima, Yosuke, Nakataki, Masahito, Strik, Werner, Wiest, Roland, Heinrichs, Markus, de Quervain, Dominique and Soravia, Leila M.. (2020). Glucocorticoids and cortical decoding in the phobic brain. Psychiatry Research: Neuroimaging. 300, p. 111066. https://doi.org/10.1016/j.pscychresns.2020.111066
Effects of a 6-week internet-based stress management program on perceived stress, subjective coping skills, and sleep quality
Stächele, Tobias, Domes, Gregor, Wekenborg, Magdalena, Penz, Marlene, Kirschbaum, Clemens and Heinrichs, Markus. (2020). Effects of a 6-week internet-based stress management program on perceived stress, subjective coping skills, and sleep quality. Frontiers in Psychiatry. 11, p. 463. https://doi.org/10.3389/fpsyt.2020.00463
An introductory guide to conducting the Trier Social Stress Test
Labuschagne, Izelle, Grace, Caitlin, Rendell, Peter, Terrett, Gillian and Heinrichs, Markus. (2019). An introductory guide to conducting the Trier Social Stress Test. Neuroscience and Biobehavioral Reviews. 107, pp. 686-695. https://doi.org/10.1016/j.neubiorev.2019.09.032
Oxytocin modulates the cognitive appraisal of the own and others close intimate relationships
Aguilar-Raab, Corina, Eckstein, Monika, Geracitano, Susanne, Prevost, Marie, Gold, Ian, Heinrichs, Markus, Bilderbeck, Amy, Ehlert, Ulrike and Ditzen, Beate. (2019). Oxytocin modulates the cognitive appraisal of the own and others close intimate relationships. Frontiers in Neuroscience. 13, p. 714. https://doi.org/10.3389/fnins.2019.00714
Effects of intranasal oxytocin administration on empathy and approach motivation in women with borderline personality disorder : A randomized controlled trial
Domes, Gregor, Ower, Nicole, von Dawans, Bernadette, Spengler, Franny B., Dziobek, Isabel, Bohus, Martin, Matthies, Swantje, Philipsen, Alexandra and Heinrichs, Markus. (2019). Effects of intranasal oxytocin administration on empathy and approach motivation in women with borderline personality disorder : A randomized controlled trial. Translational Psychiatry (online). 9(1), p. 328. https://doi.org/10.1038/s41398-019-0658-4
Oxytocin modulates the temporal dynamics of resting EEG networks
Schiller, Bastian, Koenig, Thomas and Heinrichs, Markus. (2019). Oxytocin modulates the temporal dynamics of resting EEG networks. Scientific Reports. 2019, p. 13418. https://doi.org/10.1038/s41598-019-49636-6
Oxytocin administration and emotion recognition abilities in adults with a history of childhood adversity
Schwaiger, Marion, Heinrichs, Markus and Kumsta, Robert. (2019). Oxytocin administration and emotion recognition abilities in adults with a history of childhood adversity. Psychoneuroendocrinology. 99, pp. 66-71. https://doi.org/10.1016/j.psyneuen.2018.08.025
Intimacy as related to cortisol reactivity and recovery in couples undergoing psychosocial stress
Ditzen, Beate, Germann, Janine, Meuwly, Nathalie, Bradbury, Thomas N., Bodenmann, Guy and Heinrichs, Markus. (2019). Intimacy as related to cortisol reactivity and recovery in couples undergoing psychosocial stress. Psychosomatic Medicine. 81(1), pp. 16-25. https://doi.org/10.1097/PSY.0000000000000633
Effects of acute stress on social behavior in women
von Dawans, Bernadette, Ditzen, Beate, Trueg, Amalie, Fischbacher, Urs and Heinrichs, M.. (2019). Effects of acute stress on social behavior in women. Psychoneuroendocrinology. 99, pp. 137-144. https://doi.org/10.1016/j.psyneuen.2018.08.031
Dyadic coping and its underlying neuroendocrine mechanisms - Implications for stress regulation
Zietlow, Anna-Lena, Eckstein, Monika, Hernández, Cristóbal, Nonnenmacher, Nora, Reck, Corinna, Schaer, Marcel, Bodenmann, Guy, Heinrichs, Markus and Ditzen, Beate. (2019). Dyadic coping and its underlying neuroendocrine mechanisms - Implications for stress regulation. Frontiers in Psychology. 9, p. 2600. https://doi.org/10.3389/fpsyg.2018.02600
A protective mechanism against illusory perceptions is amygdala-dependent
Spengler, Franny B., Scheele, Dirk, Kaiser, Sabrina, Heinrichs, Markus and Hurlemann, René. (2019). A protective mechanism against illusory perceptions is amygdala-dependent. The Journal of Neuroscience. 39(17), pp. 3301-3308. https://doi.org/10.1523/JNEUROSCI.2577-18.2019
Genetic variation in the maternal oxytocin system affects cortisol responsiveness to breastfeeding in infants and mothers
Krol, Kathleen M., Monakhov, Mikhail, Lai, Poh San, Ebstein, Richard P., Heinrichs, Markus and Grossmann, Tobias. (2018). Genetic variation in the maternal oxytocin system affects cortisol responsiveness to breastfeeding in infants and mothers. Adaptive Human Behavior and Physiology. 4(3), pp. 248-263. https://doi.org/10.1007/s40750-018-0090-7
The Other and Me: Effects of oxytocin on self-other distinction
L. Tomova, Markus Heinrichs and Claus Lamm. (2018). The Other and Me: Effects of oxytocin on self-other distinction. International Journal of Psychophysiology. 136(2019), pp. 49-53. https://doi.org/10.1016/j.ijpsycho.2018.03.008
The Concealed Information Test is Susceptible to Misleading Information
Katja Volz, Lisa-Marie Bahr, Markus Heinrichs, Dieter Vaitl and Wolfgang Ambach. (2018). The Concealed Information Test is Susceptible to Misleading Information. Journal of Forensic Sciences. 63(5), pp. 1419-1428. https://doi.org/10.1111/1556-4029.13718
Stress-induced body dissatisfaction in women with binge eating disorder
Eva Naumann, Jennifer Svaldi, Tanja Wyschka, Markus Heinrichs and Bernadette von Dawans. (2018). Stress-induced body dissatisfaction in women with binge eating disorder. Journal of Abnormal Psychology. 127(6), pp. 548-558. https://doi.org/10.1037/abn0000371
Positive and negative hysteresis effects for the perception of geometric and emotional ambiguities
Emanuela Liaci, Andreas Fischer, Harald Atmanspacher, Markus Heinrichs, Ludger Tebartz van Elst and Jürgen Kornmeier. (2018). Positive and negative hysteresis effects for the perception of geometric and emotional ambiguities. PLoS ONE. 13(9), pp. 1-32. https://doi.org/10.1371/journal.pone.0202398
Oxytocin and brain activity in humans: A systematic review and coordinate-based meta-analysis of functional MRI studies
Sally A. Grace, Susan Rossell, Markus Heinrichs, Catarina C. Kordsachia and Izelle Labuschagne. (2018). Oxytocin and brain activity in humans: A systematic review and coordinate-based meta-analysis of functional MRI studies. Psychoneuroendocrinology. 96, pp. 6-24. https://doi.org/10.1016/j.psyneuen.2018.05.031
Glucocorticoid administration restores salience network activity in patients with spider phobia
Leila M Soravia, Simon Schwab, Nico Weber, Masahito Nakataki, Roland Wiest, Werner Strik, Markus Heinrichs, Dominique De Quervain and Andrea Federspiel. (2018). Glucocorticoid administration restores salience network activity in patients with spider phobia. Depression and Anxiety. 35(10), pp. 925-934. https://doi.org/10.1002/da.22806
Effects of Intranasal Oxytocin Administration on Sexual Functions in Healthy Women: A Laboratory Paradigm
T. H C Kruger, Frank Deiter, Yuanyuan Zhang, Stefanie Jung, Cordula Schippert, Kai G. Kahl, Markus Heinrichs, Manfred Schedlowski and Uwe Hartmann. (2018). Effects of Intranasal Oxytocin Administration on Sexual Functions in Healthy Women: A Laboratory Paradigm. Journal of Clinical Psychopharmacology. 38(3), pp. 239-242. https://doi.org/10.1097/JCP.0000000000000863
Effects of internet-based stress management on acute cortisol stress reactivity: Preliminary evidence using the Trier Social Stress Test for Groups (TSST-G)
Gregor Domes, Tobias Stächele, Bernadette von Dawans and Markus Heinrichs. (2018). Effects of internet-based stress management on acute cortisol stress reactivity: Preliminary evidence using the Trier Social Stress Test for Groups (TSST-G). Psychoneuroendocrinology. 105, pp. 117-122. https://doi.org/10.1016/j.psyneuen.2018.12.001
Does trait anxiety influence effects of oxytocin on eye-blink startle reactivity? A randomized, double-blind, placebo-controlled crossover study
Sonja Schumacher, Misari Oe, Frank H. Wilhelm, Michael Rufer, Markus Heinrichs, Steffi Weidt, Hanspeter Moergeli and Chantal Martin-Soelch. (2018). Does trait anxiety influence effects of oxytocin on eye-blink startle reactivity? A randomized, double-blind, placebo-controlled crossover study. PLoS ONE. 13(1), pp. 1-11. https://doi.org/10.1371/journal.pone.0190809
Acute social and physical stress interact to influence social behavior: The role of social anxiety
Markus Heinrichs, Bernadette von Dawans, Amalie Trueg, Clemens Kirschbaum and Urs Fischbacher. (2018). Acute social and physical stress interact to influence social behavior: The role of social anxiety. PLoS ONE. 13(10), pp. 1-21. https://doi.org/10.1371/journal.pone.0204665
Testosterone and androgen receptor gene polymorphism are associated with confidence and competitiveness in men
Eisenegger, Christoph, Kumsta, Robert, Naef, Michael, Gromoll, Jörg and Heinrichs, Markus. (2017). Testosterone and androgen receptor gene polymorphism are associated with confidence and competitiveness in men. Hormones and Behavior. 92, pp. 93 - 102. https://doi.org/10.1016/j.yhbeh.2016.09.011
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Spengler, Franny B., Schultz, Johannes, Scheele, Dirk, Essel, Maximiliane, Maier, Wolfgang A., Heinrichs, Markus and Hurlemann, René. (2017). Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity. Biological Psychiatry. 82(12), pp. 885 - 894. https://doi.org/10.1016/j.biopsych.2017.04.015
Oxytocin and the emergence of individual differences in the social regulation of stress
Chen, Frances S., Heinrichs, Markus and Johnson, Susan C.. (2017). Oxytocin and the emergence of individual differences in the social regulation of stress. Social and Personality Psychology Compass. 11(8), pp. 1 - 9. https://doi.org/10.1111/spc3.12332
Glucocorticoid administration improves aberrant fear-processing networks in spider phobia
Nakataki, Masahito, Soravia, Leila M., Schwab, Simon, Horn, Helge, Dierks, Thomas, Strik, Werner, Wiest, Roland, Heinrichs, Markus, de Quervain, Dominique J.-F., Federspiel, Andrea and Morishima, Yosuke. (2017). Glucocorticoid administration improves aberrant fear-processing networks in spider phobia. Neuropsychopharmacology. 42(2), pp. 485 - 494. https://doi.org/10.1038/npp.2016.207
Mona Lisa is always happy - And only sometimes sad
Liaci, Emanuela, Fischer, Andreas, Heinrichs, Markus, van Elst, Ludger Tebartz and Kornmeier, Jürgen. (2017). Mona Lisa is always happy - And only sometimes sad. Scientific Reports. 7(1), pp. 1 - 10. https://doi.org/10.1038/srep43511
Social identity shapes stress appraisals in people with a history of depression
Isaksson, Alexandra, Martin, Peter, Kaufmehl, Jan, Heinrichs, Markus, Domes, Gregor and Rüsch, Nicolas. (2017). Social identity shapes stress appraisals in people with a history of depression. Psychiatry Research. 254, pp. 12 - 17. https://doi.org/10.1016/j.psychres.2017.04.021
Restoring effects of oxytocin on the attentional preference for faces in autism
Kanat, Manuela, Spenthof, Ines, Riedel, A., Van Elst, Ludger Tebartz, Heinrichs, Markus and Domes, Gregor. (2017). Restoring effects of oxytocin on the attentional preference for faces in autism. Translational Psychiatry (online). 7(4), pp. 1 - 8. https://doi.org/10.1038/tp.2017.67
Increased neural responses to empathy for pain might explain how acute stress increases prosociality
Tomova, L., Majdand, J., Hummer, A., Windischberger, C., Heinrichs, Markus and Lamm, Claus. (2017). Increased neural responses to empathy for pain might explain how acute stress increases prosociality. Social Cognitive and Affective Neuroscience. 12(3), pp. 401 - 408. https://doi.org/10.1093/scan/nsw146
Disadvantage of social sensitivity: Interaction of oxytocin receptor genotype and child maltreatment on brain structure
Dannlowski, Udo, Kugel, Harald, Grotegerd, Dominik, Redlich, Ronny, Opel, Nils, Dohm, Katharina, Zaremba, Dario, Grögler, Anne, Schwieren, Juliane, Suslow, Thomas, Ohrmann, Patricia, Bauer, Jochen, Krug, Axel, Kircher, Tilo, Jansen, Andreas, Domschke, Katharina, Hohoff, Christa, Zwitserlood, Pienie, Heinrichs, Markus, ... Baune, Bernhard T.. (2016). Disadvantage of social sensitivity: Interaction of oxytocin receptor genotype and child maltreatment on brain structure. Biological Psychiatry. 80(5), pp. 398 - 405. https://doi.org/10.1016/j.biopsych.2015.12.010
The effect of oxytocin on attention to angry and happy faces in chronic depression
Domes, Gregor, Normann, Claus and Heinrichs, Markus. (2016). The effect of oxytocin on attention to angry and happy faces in chronic depression. BMC Psychiatry. 16(1), pp. 1 - 8. https://doi.org/10.1186/s12888-016-0794-9
Cortisol modulates men's affiliative responses to acute social stress
Berger, Justus, Heinrichs, Markus, van Dawans, Bernadette, Way, Baldwin M. and Chen, Frances S.. (2016). Cortisol modulates men's affiliative responses to acute social stress. Psychoneuroendocrinology. 63, pp. 1 - 9. https://doi.org/10.1016/j.psyneuen.2015.09.004
As time goes by: Oxytocin influences the subjective perception of time in a social context
Colonnello, Valentina, Domes, Gregor and Heinrichs, Markus. (2016). As time goes by: Oxytocin influences the subjective perception of time in a social context. Psychoneuroendocrinology. 68(June), pp. 69 - 73. https://doi.org/10.1016/j.psyneuen.2016.02.015
Altering the course of schizophrenia: Progress and perspectives
Millan, Mark J., Andrieux, Annie, Bartzokis, George, Cadenhead, Kristin, Dazzan, Paola, Fusar-Poli, Paolo, Gallinat, Jürgen, Giedd, Jay, Grayson, Dennis R., Heinrichs, Markus, Kahn, René, Krebs, Marie-Odile, Leboyer, Marion, Lewis, David, Marin, Oscar, Marin, Philippe, Meyer-Lindenberg, Andreas, McGorry, Patrick, McGuire, Paul K., ... Weinberger, Daniel. (2016). Altering the course of schizophrenia: Progress and perspectives. Nature Reviews Drug Discovery. 15(7), pp. 485 - 515. https://doi.org/10.1038/nrd.2016.28
Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability
Kanthak, Magdalena K., Chen, Frances S., Kumsta, Robert, Hill, LaBarron K., Thayer, Julian F. and Heinrichs, Markus. (2016). Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability. Biological Psychology. 117, pp. 43 - 49. https://doi.org/10.1016/j.biopsycho.2016.02.007
Altered stress-induced regulation of genes in monocytes in adults with a history of childhood adversity
Schwaiger, Marion, Grinberg, Marianna, Moser, Dirk, Zang, Johannes C.S., Heinrichs, Markus, Hengstler, Jan G., Rahnenführer, Jörg, Cole, Steve and Kumsta, Robert. (2016). Altered stress-induced regulation of genes in monocytes in adults with a history of childhood adversity. Neuropsychopharmacology. 41(10), pp. 2530 - 2540. https://doi.org/10.1038/npp.2016.57
Autistic traits in patients with borderline personality disorder
Nanchen, Katia, Brodführer, Anne, Heinrichs, Markus, Philipsen, Alexandra, van Elst, Ludger Tebartz and Matthies, Swantje. (2016). Autistic traits in patients with borderline personality disorder. Zeitschrift fur Psychiatrie, Psychologie und Psychotherapie. 64(4), pp. 247 - 255. https://doi.org/10.1024/1661-4747/a000286
The German version of the gaze anxiety rating scale (GARS): Reliability and validity
Domes, Gregor, Marx, Lisa, Spenthof, Ines and Heinrichs, Markus. (2016). The German version of the gaze anxiety rating scale (GARS): Reliability and validity. PLoS ONE. 11(3), pp. 1 - 12. https://doi.org/10.1371/journal.pone.0150807
Oxytocin's inhibitory effect on food intake is stronger in obese than normal-weight men
Thienel, Matthias, Fritsche, A., Heinrichs, Markus, Peter, A., Ewers, M., Lehnert, Hendrik, Born, J. and Hallschmid, Manfred. (2016). Oxytocin's inhibitory effect on food intake is stronger in obese than normal-weight men. International Journal of Obesity. 40, pp. 1707 - 1714. https://doi.org/10.1038/ijo.2016.149
Oxytocin and self-consciousness
Colonnello, Valentina and Heinrichs, Markus. (2016). Oxytocin and self-consciousness. Frontiers in Human Neuroscience. 10(February), pp. 1 - 4. https://doi.org/10.3389/fnhum.2016.00067
Personality traits are consistent when measured in the field and in the laboratory in African striped mice (Rhabdomys pumilio)
Yuen, C. H., Pillay, N., Heinrichs, Markus, Schoepf, I. and Schradin, C.. (2016). Personality traits are consistent when measured in the field and in the laboratory in African striped mice (Rhabdomys pumilio). Behavioral Ecology and Sociobiology. 70(8), pp. 1235 - 1246. https://doi.org/10.1007/s00265-016-2131-1
Autistic traits and empathy in chronic vs. episodic depression
Domes, Gregor, Spenthof, Ines, Radtke, Martina, Isaksson, Alexandra, Normann, Claus and Heinrichs, Markus. (2016). Autistic traits and empathy in chronic vs. episodic depression. Journal of Affective Disorders. 195(May), pp. 144 - 147. https://doi.org/10.1016/j.jad.2016.02.006
Bericht der Kommission "Studium und Lehre" der Deutschen Gesellschaft für Psychologie: Teil II: Masterstudium psychologie
Abele-Brehm, Andrea, Bühner, Markus, Deutsch, Roland, Erdfelder, Edgar, Fydrich, Thomas, Gollwitzer, Mario, Heinrichs, Markus, König, Cornelius, Spinath, Birgit, Vaterrodt, Bianca and Heinke-Becker, Jesco. (2015). Bericht der Kommission "Studium und Lehre" der Deutschen Gesellschaft für Psychologie: Teil II: Masterstudium psychologie. Psychologische Rundschau. 66(1), pp. 31 - 36. https://doi.org/10.1026/0033-3042/a000248
Attachment representation modulates oxytocin effects on the processing of own-child faces in fathers
Waller, Christiane, Wittfoth, Matthias, Fritzsche, Konstantin, Timm, Lydia, Wittfoth-Schardt, Dina, Rottler, Edit, Heinrichs, Markus, Buchheim, Anna, Kiefer, Markus and Gündel, Harald. (2015). Attachment representation modulates oxytocin effects on the processing of own-child faces in fathers. Psychoneuroendocrinology. 62, pp. 27 - 35. https://doi.org/10.1016/j.psyneuen.2015.07.003
Oxytocin modulates amygdala reactivity to masked fearful eyes
Kanat, Manuela, Heinrichs, Markus, Mader, Irina, van Elst, Ludger Tebartz and Domes, Gregor. (2015). Oxytocin modulates amygdala reactivity to masked fearful eyes. Neuropsychopharmacology. 40(11), pp. 2632 - 2638. https://doi.org/10.1038/npp.2015.111
Genetic modulation of oxytocin sensitivity: A pharmacogenetic approach
Chen, Frances S., Kumsta, Robert, Dvorak, F., Domes, Gregor, Yim, O. S., Ebstein, Richard P. and Heinrichs, Markus. (2015). Genetic modulation of oxytocin sensitivity: A pharmacogenetic approach. Translational Psychiatry. 5(10), pp. 1 - 7. https://doi.org/10.1038/tp.2015.163
Effects of stress on the social support provided by men and women in intimate relationships
Bodenmann, Guy, Meuwly, Nathalie, Germann, Janine, Nussbeck, Fridtjof W., Heinrichs, Markus and Bradbury, Thomas N.. (2015). Effects of stress on the social support provided by men and women in intimate relationships. Psychological Science. 26(10), pp. 1584 - 1594. https://doi.org/10.1177/0956797615594616
Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism
Auyeung, B., Lombardo, M. V., Heinrichs, Markus, Chakrabarti, B., Sule, A., Deakin, J. B., Bethlehem, R. A.I., Dickens, L., Mooney, N., Sipple, J. A.N., Thiemann, P. and Baron-Cohen, S.. (2015). Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism. Translational Psychiatry. 5(e507), pp. 1 - 6. https://doi.org/10.1038/tp.2014.146
Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone
Bosch, Oliver G., Eisenegger, Christoph, Gertsch, Jürg, von Rotz, Robin, Dornbierer, Dario, Gachet, M. Salomé, Heinrichs, Markus, Wetter, Thomas C., Seifritz, Erich and Quednow, Boris B.. (2015). Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone. Psychoneuroendocrinology. 62(December), pp. 1 - 10. https://doi.org/10.1016/j.psyneuen.2015.07.167
Oxytocin attenuates neural reactivity to masked threat cues from the eyes
Kanat, Manuela, Heinrichs, Markus, Schwarzwald, Ralf and Domes, Gregor. (2015). Oxytocin attenuates neural reactivity to masked threat cues from the eyes. Neuropsychopharmacology. 40(2), pp. 287 - 295. https://doi.org/10.1038/npp.2014.183
Menstrual cycle phase affects discrimination of infant cuteness
Lobmaier, Janek S., Probst, Fabian, Perrett, David I. and Heinrichs, Markus. (2015). Menstrual cycle phase affects discrimination of infant cuteness. Hormones and Behavior. 70(April), pp. 1 - 6. https://doi.org/10.1016/j.yhbeh.2015.02.001
Effects of acute social stress on emotion processing in children
Chen, Frances S., Schmitz, Julian, Domes, Gregor, Tuschen-Caffier, Brunna and Heinrichs, Markus. (2014). Effects of acute social stress on emotion processing in children. Psychoneuroendocrinology. 40(1), pp. 91 - 95. https://doi.org/10.1016/j.psyneuen.2013.11.003
Oxytocin and the social brain: Neural mechanisms and perspectives in human research
Kanat, Manuela, Heinrichs, Markus and Domes, Gregor. (2014). Oxytocin and the social brain: Neural mechanisms and perspectives in human research. Brain Research. 1580(September), pp. 160 - 171. https://doi.org/10.1016/j.brainres.2013.11.003
Attachment style moderates the effects of oxytocin on social behaviors and cognitions during social rejection: Applying a research domain criteria framework to social anxiety
Fang, Angela, Hoge, Elizabeth A., Heinrichs, Markus and Hofmann, Stefan G.. (2014). Attachment style moderates the effects of oxytocin on social behaviors and cognitions during social rejection: Applying a research domain criteria framework to social anxiety. Clinical Psychological Science. 2(6), pp. 740 - 747. https://doi.org/10.1177/2167702614527948
Effects of a 12-week endurance training program on the physiological response to psychosocial stress in men: A randomized controlled trial
Klaperski, Sandra, von Dawans, Bernadette, Heinrichs, Markus and Fuchs, Reinhard. (2014). Effects of a 12-week endurance training program on the physiological response to psychosocial stress in men: A randomized controlled trial. Journal of Behavioral Medicine. 37(6), pp. 1118 - 1133. https://doi.org/10.1007/s10865-014-9562-9
Psychobiology of social support: The social dimension of stress buffering
Ditzen, Beate and Heinrichs, Markus. (2014). Psychobiology of social support: The social dimension of stress buffering. Restorative Neurology and Neuroscience. 32(1), pp. 149 - 162. https://doi.org/10.3233/RNN-139008
Oxytocin promotes facial emotion recognition and amygdala reactivity in adults with asperger syndrome
Domes, Gregor, Kumbier, Ekkehardt, Heinrichs, Markus and Herpertz, Sabine C.. (2014). Oxytocin promotes facial emotion recognition and amygdala reactivity in adults with asperger syndrome. Neuropsychopharmacology. 39(3), pp. 698 - 706. https://doi.org/10.1038/npp.2013.254
Differential effects of intranasal oxytocin on sexual experiences and partner interactions in couples
Behnia, Behnoush, Heinrichs, Markus, Bergmann, Wiebke, Jung, Stefanie, Germann, Janine, Schedlowski, Manfred, Hartmann, Uwe and Kruger, Tillmann H.C.. (2014). Differential effects of intranasal oxytocin on sexual experiences and partner interactions in couples. Hormones and Behavior. 65(3), pp. 308 - 318. https://doi.org/10.1016/j.yhbeh.2014.01.009
Oxytocin's impact on social face processing is stronger in homosexual than heterosexual men
Thienel, Matthias, Heinrichs, Markus, Fischer, Stefan, Ott, Volker, Born, Jan and Hallschmid, Manfred. (2014). Oxytocin's impact on social face processing is stronger in homosexual than heterosexual men. Psychoneuroendocrinology. 39(1), pp. 194 - 203. https://doi.org/10.1016/j.psyneuen.2013.09.013
MDMA enhances emotional empathy and prosocial behavior
Hysek, Cédric M., Schmid, Yasmin, Simmler, Linda D., Domes, Gregor, Heinrichs, Markus, Eisenegger, Christoph, Preller, Katrin H., Quednow, Boris B. and Liechti, Matthias E.. (2014). MDMA enhances emotional empathy and prosocial behavior. Social Cognitive and Affective Neuroscience. 9(11), pp. 1645 - 1652. https://doi.org/10.1093/scan/nst161
Intranasal oxytocin enhances positive self-attribution in healthy men
Colonnello, Valentina and Heinrichs, Markus. (2014). Intranasal oxytocin enhances positive self-attribution in healthy men. Journal of Psychosomatic Research. 77(5), pp. 415 - 419. https://doi.org/10.1016/j.jpsychores.2014.06.016
Oxytocin increases the likeability of physically formidable men
Chen, Frances S., Mayer, Jennifer, Mussweiler, Thomas and Heinrichs, Markus. (2014). Oxytocin increases the likeability of physically formidable men. Social Cognitive and Affective Neuroscience. 10(6), pp. 797 - 800. https://doi.org/10.1093/scan/nsu116
Glucocorticoids enhance in vivo exposure-based therapy of spider phobia
Soravia, Leila M., Heinrichs, Markus, Winzeler, Livia, Fisler, Melanie, Schmitt, Wolfgang, Horn, Helge, Dierks, Thomas, Strik, Werner, Hofmann, Stefan G. and de Quervain, Dominique J.-F.. (2014). Glucocorticoids enhance in vivo exposure-based therapy of spider phobia. Depression and Anxiety. 31(5), pp. 429 - 435. https://doi.org/10.1002/da.22219
Is stress affecting our ability to tune into others? Evidence for gender differences in the effects of stress on self-other distinction
Tomova, L., von Dawans, Bernadette, Heinrichs, Markus, Silani, G. and Lamm, C.. (2014). Is stress affecting our ability to tune into others? Evidence for gender differences in the effects of stress on self-other distinction. Psychoneuroendocrinology. 43, pp. 95 - 104. https://doi.org/10.1016/j.psyneuen.2014.02.006
Oxytocin differentially modulates eye gaze to naturalistic social signals of happiness and anger
Domes, Gregor, Steiner, Angela, Porges, Stephen W. and Heinrichs, Markus. (2013). Oxytocin differentially modulates eye gaze to naturalistic social signals of happiness and anger. Psychoneuroendocrinology. 38(7), pp. 1198 - 1202. https://doi.org/10.1016/j.psyneuen.2012.10.002
Epigenetic regulation of the oxytocin receptor gene: Implications for behavioral neuroscience
Kumsta, Robert, Hummel, Elisabeth, Chen, Frances S. and Heinrichs, Markus. (2013). Epigenetic regulation of the oxytocin receptor gene: Implications for behavioral neuroscience. Frontiers in Neuroscience. 7, pp. 1 - 6. https://doi.org/10.3389/fnins.2013.00083
Effects of intranasal oxytocin on pupil dilation indicate increased salience of socioaffective stimuli
Prehn, Kristin, Kazzer, Philipp, Lischke, Alexander, Heinrichs, Markus, Herpertz, Sabine C. and Domes, Gregor. (2013). Effects of intranasal oxytocin on pupil dilation indicate increased salience of socioaffective stimuli. Psychophysiology. 50(6), pp. 528 - 537. https://doi.org/10.1111/psyp.12042
Sex-specific effects of intranasal oxytocin on autonomic nervous system and emotional responses to couple conflict
Ditzen, Beate, Nater, Urs M., Schaer, Marcel, La Marca, Roberto, Bodenmann, Guy, Ehlert, Ulrike and Heinrichs, Markus. (2013). Sex-specific effects of intranasal oxytocin on autonomic nervous system and emotional responses to couple conflict. Social Cognitive and Affective Neuroscience. 8(8), pp. 897 - 902. https://doi.org/10.1093/scan/nss083
Oxytocin, stress and social behavior: Neurogenetics of the human oxytocin system
Kumsta, Robert and Heinrichs, Markus. (2013). Oxytocin, stress and social behavior: Neurogenetics of the human oxytocin system. Current Opinion in Neurobiology. 23(1), pp. 11 - 16. https://doi.org/10.1016/j.conb.2012.09.004
Effects of intranasal oxytocin on the neural basis of face processing in autism spectrum disorder
Domes, Gregor, Heinrichs, Markus, Kumbier, Ekkehardt, Grossmann, Annette, Hauenstein, Karlheinz and Herpertz, Sabine C.. (2013). Effects of intranasal oxytocin on the neural basis of face processing in autism spectrum disorder. Biological Psychiatry. 74(3), pp. 164 - 171. https://doi.org/10.1016/j.biopsych.2013.02.007
In the eye of the beholder: Eye contact increases resistance to persuasion
Chen, Frances S., Minson, Julia A., Schöne, Maren and Heinrichs, Markus. (2013). In the eye of the beholder: Eye contact increases resistance to persuasion. Psychological Science. 24(11), pp. 2254 - 2261. https://doi.org/10.1177/0956797613491968
Oxytocin reduces reward-driven food intake in humans
Ott, Volker, Finlayson, Graham, Lehnert, Hendrik, Heitmann, Birte, Heinrichs, Markus, Born, Jan and Hallschmid, Manfred. (2013). Oxytocin reduces reward-driven food intake in humans. Diabetes. 62(10), pp. 3418 - 3425. https://doi.org/10.2337/db13-0663
Oxytocin sharpens self-other perceptual boundary
Colonnello, Valentina, Chen, Frances S., Panksepp, Jaak and Heinrichs, Markus. (2013). Oxytocin sharpens self-other perceptual boundary. Psychoneuroendocrinology. 38(12), pp. 2996 - 3002. https://doi.org/10.1016/j.psyneuen.2013.08.010
Neuropeptide S receptor gene is associated with cortisol responses to social stress in humans
Kumsta, Robert, Chen, Frances S., Pape, Hans-Christian and Heinrichs, Markus. (2013). Neuropeptide S receptor gene is associated with cortisol responses to social stress in humans. Biological Psychology. 93(2), pp. 304 - 307. https://doi.org/10.1016/j.biopsycho.2013.02.018
Intranasal oxytocin increases covert attention to positive social cues
Domes, Gregor, Sibold, M., Schulze, L., Lischke, Alexander, Herpertz, Sabine C. and Heinrichs, Markus. (2013). Intranasal oxytocin increases covert attention to positive social cues. Psychological Medicine. 43(8), pp. 1747 - 1753. https://doi.org/10.1017/S0033291712002565
Does the level of physical exercise affect physiological and psychological responses to psychosocial stress in women?
Klaperski, Sandra, von Dawans, Bernadette, Heinrichs, Markus and Fuchs, Reinhard. (2013). Does the level of physical exercise affect physiological and psychological responses to psychosocial stress in women? Psychology of Sport and Exercise. 14(2), pp. 266 - 274. https://doi.org/10.1016/j.psychsport.2012.11.003
The social dimension of stress reactivity: Acute stress increases prosocial behavior in humans
von Dawans, Bernadette, Fischbacher, Urs, Kirschbaum, Clemens, Fehr, Ernst and Heinrichs, Markus. (2012). The social dimension of stress reactivity: Acute stress increases prosocial behavior in humans. Psychological Science. 23(6), pp. 651 - 660. https://doi.org/10.1177/0956797611431576
Oxytocin increases amygdala reactivity to threatening scenes in females
Lischke, Alexander, Gamer, Matthias, Berger, Christoph, Grossmann, Annette, Hauenstein, Karlheinz, Heinrichs, Markus, Herpertz, Sabine C. and Domes, Gregor. (2012). Oxytocin increases amygdala reactivity to threatening scenes in females. Psychoneuroendocrinology. 37(9), pp. 1431 - 1438. https://doi.org/10.1016/j.psyneuen.2012.01.011
Dyadic coping, insecure attachment, and cortisol stress recovery following experimentally induced stress
Meuwly, Nathalie, Bodenmann, Guy, Germann, Janine, Bradbury, Thomas N., Ditzen, Beate and Heinrichs, Markus. (2012). Dyadic coping, insecure attachment, and cortisol stress recovery following experimentally induced stress. Journal of Family Psychology. 26(6), pp. 937 - 947. https://doi.org/10.1037/a0030356
Oxytocin modulates neural reactivity to children's faces as a function of social salience
Wittfoth-Schardt, Dina, Gründing, Johanna, Wittfoth, Matthias, Lanfermann, Heinrich, Heinrichs, Markus, Domes, Gregor, Buchheim, Anna, Gündel, Harald and Waller, Christiane. (2012). Oxytocin modulates neural reactivity to children's faces as a function of social salience. Neuropsychopharmacology. 37(8), pp. 1799 - 1807. https://doi.org/10.1038/npp.2012.47
Intranasal oxytocin enhances emotion recognition from dynamic facial expressions and leaves eye-gaze unaffected
Lischke, Alexander, Berger, Christoph, Prehn, Kristin, Heinrichs, Markus, Herpertz, Sabine C. and Domes, Gregor. (2012). Intranasal oxytocin enhances emotion recognition from dynamic facial expressions and leaves eye-gaze unaffected. Psychoneuroendocrinology. 37(4), pp. 475 - 481. https://doi.org/10.1016/j.psyneuen.2011.07.015
Medial frontal hyperactivity to sad faces in generalized social anxiety disorder and modulation by oxytocin
Labuschagne, Izelle, Phan, K. Luan, Wood, Amanda, Angstadt, Mike, Chua, Phyllis, Heinrichs, Markus, Stout, Julie C., Nathan, Pradeep J. and Pradeep,. (2012). Medial frontal hyperactivity to sad faces in generalized social anxiety disorder and modulation by oxytocin. International Journal of Neuropsychopharmacology (print). 15(7), pp. 883 - 896. https://doi.org/10.1017/S1461145711001489
Oxytocin
Heinrichs, Markus, Chen, Frances S. and Domes, Gregor. (2012). Oxytocin. In In S. G. Hofmann (Ed.). Psychobiological approaches for anxiety disorders: Treatment combination strategies pp. 123 - 143 John Wiley & Sons. https://doi.org/10.1002/9781119945901.ch8
The Trier Social Stress Test for Groups (TSST-G): A new research tool for controlled simultaneous social stress exposure in a group format
von Dawans, Bernadette, Kirschbaum, Clemens and Heinrichs, Markus. (2011). The Trier Social Stress Test for Groups (TSST-G): A new research tool for controlled simultaneous social stress exposure in a group format. Psychoneuroendocrinology. 36(4), pp. 514 - 522. https://doi.org/10.1016/j.psyneuen.2010.08.004
Alexithymic traits and facial emotion recognition in borderline personality disorder
Domes, Gregor, Grabe, Hans Jörgen, Czieschnek, Daniela, Heinrichs, Markus and Herpertz, Sabine C.. (2011). Alexithymic traits and facial emotion recognition in borderline personality disorder. Psychotherapy and Psychosomatics. 80(6), pp. 383 - 385. https://doi.org/10.1159/000325828
Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans
Chen, Frances S., Kumsta, Robert, von Dawans, Bernadette, Monakhov, Mikhail, Ebstein, Richard P. and Heinrichs, Markus. (2011). Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans. Proceedings of the National Academy of Sciences of the United States of America. 108(50), pp. 19937 - 19942. https://doi.org/10.1073/pnas.1113079108
Oxytocin and vasopressin in the human brain: Social neuropeptides for translational medicine
Meyer-Lindenberg, Andreas, Domes, Gregor, Kirsch, Peter and Heinrichs, Markus. (2011). Oxytocin and vasopressin in the human brain: Social neuropeptides for translational medicine. Nature Reviews Neuroscience. 12(9), pp. 524 - 538. https://doi.org/10.1038/nrn3044
Oxytocin increases recognition of masked emotional faces
Schulze, Lars, Lischke, Alexander, Greif, Jonas, Herpertz, Sabine C., Heinrichs, Markus and Domes, Gregor. (2011). Oxytocin increases recognition of masked emotional faces. Psychoneuroendocrinology. 36(9), pp. 1378 - 1382. https://doi.org/10.1016/j.psyneuen.2011.03.011
Prejudice and truth about the effect of testosterone on human bargaining behaviour
Eisenegger, C., Naef, M., Snozzi, R., Heinrichs, Markus and Fehr, Ernst. (2010). Prejudice and truth about the effect of testosterone on human bargaining behaviour. Nature. 463(7279), pp. 356 - 359. https://doi.org/10.1038/nature08711
Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder
Labuschagne, Izelle, Phan, K. Luan, Wood, Amanda G., Angstadt, Mike, Chua, Phyllis, Heinrichs, Markus, Stout, Julie C. and Nathan, Pradeep. (2010). Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder. Neuropsychopharmacology. 35(12), pp. 2403 - 2413. https://doi.org/10.1038/npp.2010.123
Closeness in relationships as a mediator between sexual abuse in childhood or adolescence and psychopathological outcome in adulthood
Dimitrova, Nevena, Pierrehumbert, Blaise, Glatz, Nathalie, Torrisi, Raffaella, Heinrichs, Markus, Halfon, Oliver and Chouchena, Oliver. (2010). Closeness in relationships as a mediator between sexual abuse in childhood or adolescence and psychopathological outcome in adulthood. Clinical Psychology and Psychotherapy: an international journal of theory and practice. 17(3), pp. 183 - 195. https://doi.org/10.1002/cpp.650
Effects of intranasal oxytocin on emotional face processing in women
Domes, Gregor, Lischke, Alexander, Berger, Christoph, Grossmann, Annette, Hauenstein, Karlheinz, Heinrichs, Markus and Herpertz, Sabine C.. (2010). Effects of intranasal oxytocin on emotional face processing in women. Psychoneuroendocrinology. 35(1), pp. 83 - 93. https://doi.org/10.1016/j.psyneuen.2009.06.016
The neural correlates of sex differences in emotional reactivity and emotion regulation
Domes, Gregor, Schulze, L., Böttger, Moritz, Grossmann, Annette, Hauenstein, Karlheinz, Wirtz, Petra H., Heinrichs, Markus and Herpertz, Sabine C.. (2010). The neural correlates of sex differences in emotional reactivity and emotion regulation. Human Brain Mapping. 31(5), pp. 758 - 769. https://doi.org/10.1002/hbm.20903
Maternal cortisol in late pregnancy and hypothalamicpituitaryadrenal reactivity to psychosocial stress postpartum in women
Meinlschmidt, Gunther, Martin, Cyrill, Neumann, Inga D. and Heinrichs, Markus. (2010). Maternal cortisol in late pregnancy and hypothalamicpituitaryadrenal reactivity to psychosocial stress postpartum in women. Stress: the International Journal on the Biology of Stress. 13(2), pp. 163 - 171. https://doi.org/10.3109/10253890903128632
Oxytocin enhances the experience of attachment security
Buchheim, Anna, Heinrichs, Markus, George, Carol, Pokorny, Dan, Koops, Eva, Henningsen, Peter, O'Connor, Mary Frances and Gündel, Harald. (2009). Oxytocin enhances the experience of attachment security. Psychoneuroendocrinology. 34(9), pp. 1417 - 1422. https://doi.org/10.1016/j.psyneuen.2009.04.002
The influence of attachment on perceived stress and cortisol response to acute stress in women sexually abused in childhood or adolescence
Pierrehumbert, Blaise, Torrisi, Raffaella, Glatz, Nathalie, Dimitrova, Nevena, Heinrichs, Markus and Halfon, Oliver. (2009). The influence of attachment on perceived stress and cortisol response to acute stress in women sexually abused in childhood or adolescence. Psychoneuroendocrinology. 34(6), pp. 924 - 938. https://doi.org/10.1016/j.psyneuen.2009.01.006
The level of physical activity affects adrenal and cardiovascular reactivity to psychosocial stress
Rimmele, Ulrike, Seiler, Roland, Marti, Bernard, Wirtz, Petra H., Ehlert, Ulrike and Heinrichs, Markus. (2009). The level of physical activity affects adrenal and cardiovascular reactivity to psychosocial stress. Psychoneuroendocrinology. 34(2), pp. 190 - 198. https://doi.org/10.1016/j.psyneuen.2008.08.023
Oxytocin makes a face in memory familiar
Rimmele, Ulrike, Hediger, Karin, Heinrichs, Markus and Klaver, Peter. (2009). Oxytocin makes a face in memory familiar. Journal of Neuroscience. 29(1), pp. 38 - 42. https://doi.org/10.1523/JNEUROSCI.4260-08.2009
Intranasal Oxytocin Increases Positive Communication and Reduces Cortisol Levels During Couple Conflict
Ditzen, Beate, Schaer, Marcel, Gabriel, Barbara, Bodenmann, Guy, Ehlert, Ulrike and Heinrichs, Markus. (2009). Intranasal Oxytocin Increases Positive Communication and Reduces Cortisol Levels During Couple Conflict. Biological Psychiatry. 65(9), pp. 728 - 731. https://doi.org/10.1016/j.biopsych.2008.10.011
Glucocorticoids do not reduce subjective fear in healthy subjects exposed to social stress
Soravia, Leila M., De Quervain, Dominique and Heinrichs, Markus. (2009). Glucocorticoids do not reduce subjective fear in healthy subjects exposed to social stress. Biological Psychology. 81(3), pp. 184 - 188. https://doi.org/10.1016/j.biopsycho.2009.04.001
Oxytocin, vasopressin, and human social behavior
Heinrichs, Markus, von Dawans, Bernadette and Domes, Gregor. (2009). Oxytocin, vasopressin, and human social behavior. Frontiers in Neuroendocrinology. 30(4), pp. 548 - 557. https://doi.org/10.1016/j.yfrne.2009.05.005
Adult attachment and social support interact to reduce psychological but not cortisol responses to stress
Ditzen, Beate, Schmidt, Silke, Strauss, Bernhard, Nater, U M., Ehlert, Ulrike and Heinrichs, Markus. (2008). Adult attachment and social support interact to reduce psychological but not cortisol responses to stress. Journal of Psychosomatic Research. 64(5), pp. 479 - 486. https://doi.org/10.1016/j.jpsychores.2007.11.011
Effects of Oxytocin and Prosocial Behavior on Brain Responses to Direct and Vicariously Experienced Pain
Singer, Tania, Snozzi, R., Bird, Geoffrey, Petrovic, Predrag, Silani, G., Heinrichs, Markus and Dolan, Raymond J.. (2008). Effects of Oxytocin and Prosocial Behavior on Brain Responses to Direct and Vicariously Experienced Pain. Emotion. 8(6), pp. 781 - 791. https://doi.org/10.1037/a0014195
Oxytocin Shapes the Neural Circuitry of Trust and Trust Adaptation in Humans
Baumgartner, Thomas, Heinrichs, Markus, Vonlanthen, Aline, Fischbacher, Urs and Fehr, Ernst. (2008). Oxytocin Shapes the Neural Circuitry of Trust and Trust Adaptation in Humans. Neuron. 58(4), pp. 639 - 650. https://doi.org/10.1016/j.neuron.2008.04.009
The acute effects of intranasal oxytocin administration on endocrine and sexual function in males
Burri, Andrea, Heinrichs, Markus, Schedlowski, Manfred and Kruger, T. H. C.. (2008). The acute effects of intranasal oxytocin administration on endocrine and sexual function in males. Psychoneuroendocrinology. 33(5), pp. 591 - 600. https://doi.org/10.1016/j.psyneuen.2008.01.014
Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans
Heinrichs, Markus and Domes, Gregor. (2008). Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans. Progress in Brain Research. 170, pp. 337 - 350. https://doi.org/10.1016/S0079-6123(08)00428-7
Oxytocin Improves "Mind-Reading" in Humans
Domes, Gregor, Heinrichs, Markus, Michel, Andre, Berger, Christoph and Herpertz, Sabine C.. (2007). Oxytocin Improves "Mind-Reading" in Humans. Biological Psychiatry. 61(6), pp. 731 - 733. https://doi.org/10.1016/j.biopsych.2006.07.015
Oxytocin Attenuates Amygdala Responses to Emotional Faces Regardless of Valence
Domes, Gregor, Heinrichs, Markus, Gläscher, Jan, Büchel, Christian, Braus, Dieter F. and Herpertz, Sabine C.. (2007). Oxytocin Attenuates Amygdala Responses to Emotional Faces Regardless of Valence. Biological Psychiatry. 62(10), pp. 1187 - 1190. https://doi.org/10.1016/j.biopsych.2007.03.025
Neuroendocrine mechanisms of stress and social interaction: Implications for mental disorders
Heinrichs, Markus and Gaab, Jens. (2007). Neuroendocrine mechanisms of stress and social interaction: Implications for mental disorders. Current Opinion in Psychiatry. 20(2), pp. 158 - 162. https://doi.org/10.1097/YCO.0b013e3280146a13
Emotional and cardiovascular reactions of couples during a couple-therapeutic intervention: A pilot study
Schaer, Marcel, Ditzen, Beate, Heinrichs, Markus and Bodenmann, Guy. (2007). Emotional and cardiovascular reactions of couples during a couple-therapeutic intervention: A pilot study. Zeitschrift fuer Klinische Psychologie und Psychotherapie: Forschung und Praxis. 36(4), pp. 251 - 260. https://doi.org/10.1026/1616-3443.36.4.251
Effects of different kinds of couple interaction on cortisol and heart rate responses to stress in women
Ditzen, Beate, Neumann, Inga D., Bodenmann, Guy, von Dawans, Bernadette, Turner, Rebecca A., Ehlert, Ulrike and Heinrichs, Markus. (2007). Effects of different kinds of couple interaction on cortisol and heart rate responses to stress in women. Psychoneuroendocrinology. 32(5), pp. 565 - 574. https://doi.org/10.1016/j.psyneuen.2007.03.011
Trained men show lower cortisol, heart rate and psychological responses to psychosocial stress compared with untrained men
Rimmele, Ulrike, Zellweger, Bea Costa, Marti, Bernard, Seiler, Roland, Mohiyeddini, Changiz, Ehlert, Ulrike and Heinrichs, Markus. (2007). Trained men show lower cortisol, heart rate and psychological responses to psychosocial stress compared with untrained men. Psychoneuroendocrinology. 32(6), pp. 627 - 635. https://doi.org/10.1016/j.psyneuen.2007.04.005
Glucocorticoids reduce phobic fear in humans
Soravia, Leila M., Heinrichs, Markus, Aerni, Amanda, Maroni, Caroline, Schelling, Gustav, Ehlert, Ulrike, Roozendaal, Benno and De Quervain, Dominique. (2006). Glucocorticoids reduce phobic fear in humans. Proceedings of the National Academy of Sciences of USA. 103(14), pp. 5585 - 5590. https://doi.org/10.1073/pnas.0509184103
Oxytocin increases trust in humans
Kosfeld, Michael, Heinrichs, Markus, Zak, Paul J., Fischbacher, Urs and Fehr, Ernst. (2005). Oxytocin increases trust in humans. Nature. 435(7042), pp. 673 - 676. https://doi.org/10.1038/nature03701
Predicting posttraumatic stress symptoms from pretraumatic risk factors: A 2-year prospective follow-up study in firefighters
Heinrichs, Markus, Wagner, D., Schoch, Walter, Soravia, Leila M., Hellhammer, Dirk H. and Ehlert, Ulrike. (2005). Predicting posttraumatic stress symptoms from pretraumatic risk factors: A 2-year prospective follow-up study in firefighters. American Journal of Psychiatry. 162(12), pp. 2276 - 2286. https://doi.org/10.1176/appi.ajp.162.12.2276
Selective amnesic effects of oxytocin on human memory
Heinrichs, Markus, Meinlschmidt, Gunther, Wippich, Werner, Ehlert, Ulrike and Hellhammer, Dirk H.. (2004). Selective amnesic effects of oxytocin on human memory. Physiology & Behavior. 83(1 SPEC. ISS.), pp. 31 - 38. https://doi.org/10.1016/j.physbeh.2004.07.020
Acute stress impairs recognition for positive words - Association with stress-induced cortisol secretion
Domes, Gregor, Heinrichs, Markus, Rimmele, Ulrike, Reichwald, U. and Hautzinger, M.. (2004). Acute stress impairs recognition for positive words - Association with stress-induced cortisol secretion. Stress: the International Journal on the Biology of Stress. 7(3), pp. 173 - 181. https://doi.org/10.1080/10253890412331273213
Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
Heinrichs, Markus, Baumgartner, Thomas, Kirschbaum, Clemens and Ehlert, Ulrike. (2003). Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biological Psychiatry. 54(12), pp. 1389 - 1398. https://doi.org/10.1016/S0006-3223(03)00465-7
Lactation and stress: Protective effects of breast-feeding in humans
Heinrichs, Markus, Neumann, Inga D. and Ehlert, Ulrike. (2002). Lactation and stress: Protective effects of breast-feeding in humans. Stress: the International Journal on the Biology of Stress. 5(3), pp. 195 - 203. https://doi.org/10.1080/1025389021000010530
Hypothalamic-pituitary-adrenal axis reactivity to psychological stress and memory in middle-aged women: High responders exhibit enhanced declarative memory performance
Domes, Gregor, Heinrichs, Markus, Reichwald, U. and Hautzinger, M.. (2002). Hypothalamic-pituitary-adrenal axis reactivity to psychological stress and memory in middle-aged women: High responders exhibit enhanced declarative memory performance. Psychoneuroendocrinology. 27(7), pp. 843 - 853. https://doi.org/10.1016/S0306-4530(01)00085-3
Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women
Heinrichs, Markus, Meinlschmidt, Gunther, Neumann, Inga D., Wagner, Sabine, Kirschbaum, Clemens, Ehlert, Ulrike and Hellhammer, Dirk H.. (2001). Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women. The Journal of Clinical Endocrinology and Metabolism. 86(10), pp. 4798 - 4804. https://doi.org/10.1210/jc.86.10.4798
Psychoneuroendocrinological contributions to the etiology of depression, posttraumatic stress disorder, and stress-related bodily disorders: The role of the hypothalamus-pituitary-adrenal axis
Ehlert, Ulrike, Gaab, Jens and Heinrichs, Markus. (2001). Psychoneuroendocrinological contributions to the etiology of depression, posttraumatic stress disorder, and stress-related bodily disorders: The role of the hypothalamus-pituitary-adrenal axis. Biological Psychology. 57(43891), pp. 141 - 152. https://doi.org/10.1016/S0301-0511(01)00092-8
Social desirability scores are associated with higher morning cortisol levels in firefighters
Brody, Stuart, Wagner, D., Heinrichs, Markus, James, Alma, Hellhammer, Dirk H. and Ehlert, Ulrike. (2000). Social desirability scores are associated with higher morning cortisol levels in firefighters. Journal of Psychosomatic Research. 49(4), pp. 227 - 228. https://doi.org/10.1016/S0022-3999(00)00169-0
Psychobiological aspects of posttraumatic stress disorder
Ehlert, Ulrike, Wagner, D., Heinrichs, Markus and Heim, Christine. (1999). Psychobiological aspects of posttraumatic stress disorder. Der Nervenarzt: Monatsschrift fuer alle Gebiete nervenaerztlicher Forschung und Praxis. 70(9), pp. 773 - 779. https://doi.org/10.1007/s001150050511
Prevalence of symptoms of posttraumatic stress disorder in German professional firefighters
Wagner, D., Heinrichs, Markus and Ehlert, Ulrike. (1998). Prevalence of symptoms of posttraumatic stress disorder in German professional firefighters. American Journal of Psychiatry. 155(12), pp. 1727 - 1732. https://doi.org/10.1176/ajp.155.12.1727