Exploring new avenues for modifying course of progression of Alzheimer’s diseas e: The rise of natural medicine

Journal article

Lye, Sarah, Aust, Caitlin E., Griffiths, Lyn R. and Fernandez, Francesca. (2021). Exploring new avenues for modifying course of progression of Alzheimer’s diseas e: The rise of natural medicine. Journal of the Neurological Sciences. 422, p. 117332. https://doi.org/10.1016/j.jns.2021.117332
AuthorsLye, Sarah, Aust, Caitlin E., Griffiths, Lyn R. and Fernandez, Francesca
Abstract

With a constantly growing elderly population worldwide, a focus on developing efficient prevention and therapy for Alzheimer's disease (AD) seems timely and topical. Emphasis on natural medicine is increasingly popular in the search for drug candidates that are capable of preventing and treating AD related pathology, particularly where suppression of amyloid accumulation, neurofibrillary tangle formation, neuroinflammation and oxidative stress are equally significant. A number of phytochemical compounds have been shown to collectively reduce these AD hallmarks with the progression of natural drug candidates into human clinical trials. This review focuses on current research surrounding the therapies emerging within natural medicines and their related therapeutic potential for AD treatment.

KeywordsAlzheimer’s disease; neuro-inflammation; oxidative stress; natural medicine
Year2021
JournalJournal of the Neurological Sciences
Journal citation422, p. 117332
PublisherElsevier B.V.
ISSN1300-1817
Digital Object Identifier (DOI)https://doi.org/10.1016/j.jns.2021.117332
Scopus EID2-s2.0-85101028727
Research or scholarlyResearch
Page range1-10
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Output statusPublished
Publication dates
Online30 Jan 2021
Publication process dates
Accepted22 Jan 2021
Deposited11 Aug 2021
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