Safety of performing a graded exercise test early after stroke and transient ischemic attack

Journal article

Johnson, Liam, Kramer, Sharon F., Catanzariti, Gabriella, Kaffenberger, Tina, Cumming, Toby and Bernhardt, Julie. (2020). Safety of performing a graded exercise test early after stroke and transient ischemic attack. Physical Medicine and Rehabilitation. 12(5), pp. 445-453. https://doi.org/10.1002/pmrj.12259
AuthorsJohnson, Liam, Kramer, Sharon F., Catanzariti, Gabriella, Kaffenberger, Tina, Cumming, Toby and Bernhardt, Julie
Abstract

Background
Low cardiorespiratory fitness (CRF) is a predictor of stroke risk and poor outcome poststroke. Fitness levels are rarely assessed in the acute phase and it is unclear if it is safe for stroke survivors and people with transient ischemic attack (TIA) to perform a graded exercise test to assess fitness.

Objective
To determine if people within 14 days post stroke can safely perform a graded exercise test.

Design
Observational study.

Setting
Research institute.

Participants
People with stroke or TIA admitted to an acute stroke unit.

Intervention
Not applicable.

Main Outcome Measures
Safety of performing a graded exercise test early post stroke. Safety outcomes were (1) occurrence of an adverse event or (2) <85% blood oxygen saturation (SpO2). Participants performed a graded exercise test on a recumbent stepper at a research institute <2 weeks postevent. CRF was determined by measuring peak volume of oxygen uptake (VO2peak) using a metabolic cart.

Results
Twenty-nine participants were enrolled in the study (median age 69 years; interquartile range 58-75). Sixteen were diagnosed with TIA and 13 with a mild stroke. Twenty-eight participants completed the test; one participant was unable to perform the test due to back pain. The test was terminated due to standardized stopping criteria in 26 cases (5 = volitional fatigue, 6 = unable to keep required cadence, 15 = reaching 85% HRmax), one due to safety (ie, SpO2 < 85%), and one was inadvertently terminated before stopping criteria were reached. Average CRF determined by the exercise test was low; mean VO2peak of 16.2 ± 4.5 mL/kg/min for men (n = 20) and 12.4 ± 3.6 mL/kg/min for women (n = 8).

Conclusions
Determining exercise capacity early post stroke and TIA using a graded exercise test appears to be safe in patients with mild deficits. This information should be useful to plan tailored exercise programs. Further research should focus on determining safety of exercise testing in more severely affected stroke survivors.

Year2020
JournalPhysical Medicine and Rehabilitation
Journal citation12 (5), pp. 445-453
PublisherJohn Wiley & Sons, Inc.
ISSN1934-1482
Digital Object Identifier (DOI)https://doi.org/10.1002/pmrj.12259
Scopus EID2-s2.0-85076176031
Research or scholarlyResearch
Page range445-453
Author's accepted manuscript
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Open
Publisher's version
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All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online27 Nov 2019
Publication process dates
Accepted23 Sep 2019
Deposited17 Aug 2021
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