Dietary protein to maintain muscle mass in aging : A case for per-meal protein recommendations

Journal article


Murphy, C. H., Oikawa, S.Y. and Phillips, S.M.. (2016). Dietary protein to maintain muscle mass in aging : A case for per-meal protein recommendations. The Journal of Frailty and Aging. 5(1), pp. 49-58. https://doi.org/10.14283/jfa.2016.80
AuthorsMurphy, C. H., Oikawa, S.Y. and Phillips, S.M.
Abstract

It is well accepted that daily protein intake is an important dietary consideration to limit and treat age-related declines in muscle mass, strength, and function. Furthermore, we propose that there is a growing appreciation for the need to consider protein intake on a per-meal basis rather than simply focusing on the total daily protein intake. The existence of a saturable dose-response relationship between muscle protein synthesis (MPS) and the quantity of protein consumed in a single meal/bolus provides the rationale for promoting an even/balanced pattern of daily protein intake. We hypothesize that a balanced/even protein intake pattern with the ingestion a quantity of protein shown to optimally stimulate MPS at each meal may be an effective strategy to alleviate sarcopenic muscle loss. In this review we examine the available evidence supporting the influence of dietary protein intake pattern on muscle protein turnover, muscle mass, and muscle function. We present several practical considerations that, it is proposed, should be taken into account when translating a per-meal protein recommendation into dietary advice for older adults.

Keywordssarcopenia; muscle mass; leucine; protein turnover
Year2016
JournalThe Journal of Frailty and Aging
Journal citation5 (1), pp. 49-58
PublisherSerdi Publisher
ISSN2260-1341
Digital Object Identifier (DOI)https://doi.org/10.14283/jfa.2016.80
Scopus EID2-s2.0-84973408529
Research or scholarlyResearch
Page range49-58
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online2016
Publication process dates
Accepted02 Nov 2015
Deposited08 Sep 2021
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