Immunotherapy for non-small cell lung cancer (NSCLC), as a stand-alone and in combination therapy

Journal article

Kaur, Jasmine, Elms, Jackson, Munn, Alan L., Good, David and Wei, Ming Q.. (2021). Immunotherapy for non-small cell lung cancer (NSCLC), as a stand-alone and in combination therapy. Critical Reviews in Oncology Hematology. 164, p. Article: 103417. https://doi.org/10.1016/j.critrevonc.2021.103417
AuthorsKaur, Jasmine, Elms, Jackson, Munn, Alan L., Good, David and Wei, Ming Q.
Abstract

Non-small cell lung cancer (NSCLC) is of major concern for society as it is associated with high mortality and is one of the most commonly occurring of all cancers. Due to the number of mutational variants and general heterogeneity of this type of cancer, treatment using conventional modalities has been challenging. Therefore, it is important to have improved therapeutic treatments like immunotherapy, that can specifically treat the disease while causing minimal damage to healthy tissue and additionally provide systemic immunity. Cancer vaccines are an important element of cancer immunotherapy and have been approved for treatment of a limited number of cancers, including NSCLC. This article highlights scientific evidence for several therapeutic treatment strategies for NSCLC, alone or in combination, which offers new hope for those suffering. Although cancer vaccines have had some success as a monotherapy, their potential in a combination therapy needs to be critically analyzed for future applications.

Year2021
JournalCritical Reviews in Oncology Hematology
Journal citation164, p. Article: 103417
PublisherElsevier Ireland Ltd.
ISSN1040-8428
Digital Object Identifier (DOI)https://doi.org/10.1016/j.critrevonc.2021.103417
Scopus EID2-s2.0-85109674176
Research or scholarlyResearch
Page range1-13
Publisher's version
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All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online07 Jul 2021
Publication process dates
Accepted04 Jul 2021
Deposited19 Oct 2021
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