Overlap of autism spectrum disorder and borderline personality disorder : A systematic review and meta-analysis

Journal article


May, Tamara, Pilkington, Pamela D., Younan, Rita and Williams, Katrina. (2021). Overlap of autism spectrum disorder and borderline personality disorder : A systematic review and meta-analysis. Autism Research. 14(12), pp. 2688-2710. https://doi.org/10.1002/aur.2619
AuthorsMay, Tamara, Pilkington, Pamela D., Younan, Rita and Williams, Katrina
Abstract

Autism spectrum disorder (ASD) and borderline personality Disorder (BPD) share features, including social and emotion regulation difficulties. The evidence for the overlap in prevalence and clinical characteristics was systematically reviewed. Ovid Medline, PsycInfo, and PubMed were searched until November 30, 2020 using keywords relating to BPD and ASD. Studies that reported on the overlap of ASD and BPD diagnoses or traits and used a case, cohort, or case-controlled design were included. Of 1633 screened studies, 19 were included, of which 12 reported data suitable for meta-analysis. Most samples were of small, clinically ascertained groups, with 11 having high risk of bias. The pooled prevalence of BPD in ASD was 4% [95% CI 0%–9%] and of ASD in BPD, 3% [95% CI 1%–8%]. There were inconsistent findings across clinical areas. The prevalence of a dual diagnosis of BPD in ASD cohorts and of ASD in BPD cohorts was within population prevalence estimates of each disorder. Based on this data we were not able to assess whether there is misdiagnosis of one in favor of the other. Neurocognitive differences may underlie similar behavioral symptoms, but further research using larger, well-validated samples is needed.

Lay Summary
Autism spectrum disorder (ASD) and borderline personality disorder (BPD) have overlaps in their symptoms. The overlap in how frequently they co-occur and their presentation was systematically reviewed. We searched the key databases and including all studies that reported on the overlap of ASD and BPD diagnoses or traits and used a case, cohort or case-controlled design. Of 1633 studies, 19 were included, of which 12 reported data suitable for pooling. Most samples were of small, clinical groups, with 11 having high risk of bias. The pooled prevalence of BPD in ASD was 4% [95% CI 0%–9%] and of ASD in BPD, 3% [95% CI 1%–8%]. There were inconsistent findings across studies comparing ASD and BPD related symptoms and problems. The prevalence of a dual diagnosis of BPD in ASD cohorts and of ASD in BPD cohorts was similar to the population prevalence of each disorder. Further research using larger, well-validated samples is needed.

Keywordsautism spectrum disorder; borderline personality disorderc
Year2021
JournalAutism Research
Journal citation14 (12), pp. 2688-2710
PublisherJohn Wiley & Sons
ISSN1939-3792
Digital Object Identifier (DOI)https://doi.org/10.1002/aur.2619
Scopus EID2-s2.0-85116360559
Research or scholarlyResearch
Page range2688-2710
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online05 Oct 2021
Publication process dates
Accepted20 Sep 2021
Deposited25 Feb 2022
Permalink -

https://acuresearchbank.acu.edu.au/item/8x5z3/overlap-of-autism-spectrum-disorder-and-borderline-personality-disorder-a-systematic-review-and-meta-analysis

Restricted files

Publisher's version

  • 256
    total views
  • 0
    total downloads
  • 1
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Early maladaptive schemas and depression in adulthood : A systematic review and meta-analysis
Bishop, Amy, Younan, Rita, Low, Jennifer and Pilkington, Pamela. (2022). Early maladaptive schemas and depression in adulthood : A systematic review and meta-analysis. Clinical Psychology and Psychotherapy. 29(1), pp. 111-130. https://doi.org/10.1002/cpp.2630
Parental separation or divorce and adulthood attachment : The mediating role of the Abandonment schema
D'Rozario, Annelyse B. and Pilkington, Pamela. (2022). Parental separation or divorce and adulthood attachment : The mediating role of the Abandonment schema. Clinical Psychology and Psychotherapy. 29(2), pp. 664-675. https://doi.org/10.1002/cpp.2659
Mothers’ worries during pregnancy : A content analysis of reddit posts
Pilkington, Pamela and Bedford-Dyer, Isabella. (2021). Mothers’ worries during pregnancy : A content analysis of reddit posts. The Journal of Perinatal Education. 30(2), pp. 98-107. https://doi.org/10.1891/J-PE-D-20-00018
Early maladaptive schemas and intimate partner violence victimization and perpetration : A systematic review and meta-analysis
Pilkington, Pamela D., Noonan, Clare, May, Tamara, Younan, Rita and Holt, Ruth A.. (2021). Early maladaptive schemas and intimate partner violence victimization and perpetration : A systematic review and meta-analysis. Clinical Psychology and Psychotherapy. 28(5), pp. 1030-1039. https://doi.org/10.1002/cpp.2558
Intimate partner violence and child attachment : A systematic review and meta-analysis
Noonan, C. and Pilkington, P.. (2020). Intimate partner violence and child attachment : A systematic review and meta-analysis. Child Abuse and Neglect. 109, p. 104765. https://doi.org/10.1016/j.chiabu.2020.104765
Adverse childhood experiences and early maladaptive schemas in adulthood : A systematic review and meta-analysis
Pilkington, Pamela D., Bishop, Amy and Younan, Rita. (2020). Adverse childhood experiences and early maladaptive schemas in adulthood : A systematic review and meta-analysis. Clinical Psychology and Psychotherapy. 28(3), pp. 569-584. https://doi.org/10.1002/cpp.2533
Systematic review of the impact of coparenting interventions on paternal coparenting behaviour
Pilkington, Pamela, Rominov, Holly, Brown, Hilary K. and Dennis, Cindy-Lee. (2019). Systematic review of the impact of coparenting interventions on paternal coparenting behaviour. Journal of Advanced Nursing. 75(1), pp. 17 - 29. https://doi.org/10.1111/jan.13815
A systematic review of factors related to parents’ treatment decisions for their children with autism spectrum disorders
Wilson, Meghan, Hamilton, David, Whelan, Thomas and Pilkington, Pamela. (2018). A systematic review of factors related to parents’ treatment decisions for their children with autism spectrum disorders. Research in Autism Spectrum Disorders. 48, pp. 17 - 35. https://doi.org/10.1016/j.rasd.2018.01.004
The prevalence and correlates of self-harm ideation trajectories in Australian women from pregnancy to 4-years postpartum
Giallo, Rebecca, Pilkington, Pamela, Borschmann, Rohan, Seymour, Monique, Dunning, Melissa and Brown, Stephanie. (2018). The prevalence and correlates of self-harm ideation trajectories in Australian women from pregnancy to 4-years postpartum. Journal of Affective Disorders. 229, pp. 152 - 158. https://doi.org/10.1016/j.jad.2017.12.064
Physical, sexual and social health factors associated with the trajectories of maternal depressive symptoms from pregnancy to 4 years postpartum
Giallo, Rebecca, Pilkington, Pamela, McDonald, Ellie, Gartland, Deirdre, Woolhouse, Hannah and Brown, Stephanie. (2017). Physical, sexual and social health factors associated with the trajectories of maternal depressive symptoms from pregnancy to 4 years postpartum. Social Psychiatry and Psychiatric Epidemiology. 52(7), pp. 815 - 828. https://doi.org/10.1007/s00127-017-1387-8
Fathers’ worries during pregnancy: A qualitative content analysis of reddit
Pilkington, Pamela and Rominov, Holly. (2017). Fathers’ worries during pregnancy: A qualitative content analysis of reddit. The Journal of Perinatal Education. 26(4), pp. 208 - 218. https://doi.org/10.1891/1058-1243.26.4.208
Modifiable partner factors associated with perinatal depression and anxiety : A systematic review and meta-analysis
Pilkington, Pamela, Milne, Lisa, Cairns, Kathryn, Lewis, James and Whelan, Thomas. (2015). Modifiable partner factors associated with perinatal depression and anxiety : A systematic review and meta-analysis. Journal of Affective Disorders (Print). 178, pp. 165 - 180. https://doi.org/10.1016/j.jad.2015.02.023
Parenting strategies for reducing the risk of adolescent depression and anxiety disorders: A Delphi consensus study
Marie B.H. Yap, Pamela D. Pilkington, Siobhan M. Ryan, Claire M. Kelly and Anthony F. Jorm. (2014). Parenting strategies for reducing the risk of adolescent depression and anxiety disorders: A Delphi consensus study. Journal of Affective Disorders. 156, pp. 67-75. https://doi.org/10.1016/j.jad.2013.11.017