Genetics of dementia : A focus on Alzheimer's disease

Book chapter

Fernandez, Francesca and Andrews, Jessica L.. (2020). Genetics of dementia : A focus on Alzheimer's disease. In In Martin, Colin R. and Preedy, Victor R. (Ed.). The neuroscience of dementia ; volume 1 pp. 127-146 Academic Press. https://doi.org/10.1016/B978-0-12-815854-8.00009-4
AuthorsFernandez, Francesca and Andrews, Jessica L.
EditorsMartin, Colin R. and Preedy, Victor R.
Abstract

This chapter focuses on providing a brief overview of genes associated with sporadic (late-onset) Alzheimer's disease (AD). Despite decades of research, no current and reliable test is currently available for the diagnosis of AD. Genetic biomarkers are promising for both diagnostic tools and tailored profiling therapy. Genes associated with sporadic AD through linkage, association, and genome-wide association case studies are briefly described. We also discuss the genes underlying cognitive function in the context of AD.

Keywordscognitive dysfunction; genetic biomarkers cognitive related genes; genetic risk factors; late-onset; Alzheimer's disease
Page range127-146
Year2020
Book titleThe neuroscience of dementia ; volume 1
PublisherAcademic Press
Place of publicationLondon, United Kingdom
San Diego, CA
Cambridge, MA
Oxford, United Kingdom
ISBN9780128160435
9780128160442
9780128158548
Digital Object Identifier (DOI)https://doi.org/10.1016/B978-0-12-815854-8.00009-4
Scopus EID2-s2.0-85126402983
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Output statusPublished
Publication dates
Print2020
Online14 Aug 2020
Publication process dates
Deposited05 Apr 2022
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