Acceptability and preliminary efficacy of a web-and telephone-based personalised exercise intervention for individuals with metastatic prostate cancer : The exercise guide pilot randomised controlled trial
Journal article
Evans, Holly E. L., Galvão, Daniel A., Forbes, Cynthia C., Girard, Danielle, Vandelanotte, Corneel, Newton, Robert U., Vincent, Andrew D., Wittert, Gary, Kichenadasse, Ganessan, Chambers, Suzanne, Brook, Nicholas and Short, Camille E.. (2021). Acceptability and preliminary efficacy of a web-and telephone-based personalised exercise intervention for individuals with metastatic prostate cancer : The exercise guide pilot randomised controlled trial. Cancers. 13(23), p. Article 5925. https://doi.org/10.3390/cancers13235925
Authors | Evans, Holly E. L., Galvão, Daniel A., Forbes, Cynthia C., Girard, Danielle, Vandelanotte, Corneel, Newton, Robert U., Vincent, Andrew D., Wittert, Gary, Kichenadasse, Ganessan, Chambers, Suzanne, Brook, Nicholas and Short, Camille E. |
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Abstract | Preliminary research has shown the effectiveness of supervised exercise-based interventions in alleviating sequela resulting from metastatic prostate cancer. However, many individuals encounter barriers that limit the uptake of face-to-face exercise. Technology-enabled interventions offer a distance-based alternative. This pilot study aimed to explore the acceptability, safety and preliminary efficacy of a web-based exercise intervention (ExerciseGuide) in individuals with metastatic prostate cancer. Forty participants (70.2 ± 8.5 years) with metastatic prostate cancer were randomised into the 8-week intervention (N = 20) or a wait-list control (N = 20). The intervention arm had access to a computer-tailored website, personalised exercise prescription and remote supervision. ExerciseGuide was deemed acceptable with a score ≥20 on the client satisfaction questionnaire; however, the usability score was just below the pre-specified score of ≥68 on the software usability scale. There were no serious adverse events reported. Moderate-to-vigorous physical activity levels between baseline and follow-ups were significantly higher (10.0 min per day; 95% CI = (1.3–18.6); p = 0.01) in the intervention group compared to wait-list control. There were also greater improvements in step count (1332; 95% CI = (159–2505); p = 0.02) and identified motivation (0.4, 95% CI = (0.0, 0.7); p = 0.04). Our findings provide preliminary evidence that ExerciseGuide is acceptable, safe and efficacious among individuals with metastatic prostate cancer. |
Keywords | exercise; metastatic prostate cancer; behavioural change; eHealth; computer-tailoring; usability; acceptability; rct |
Year | 2021 |
Journal | Cancers |
Journal citation | 13 (23), p. Article 5925 |
Publisher | Multidisciplinary Digital Publishing Institute (MDPI AG) |
ISSN | 2072-6694 |
Digital Object Identifier (DOI) | https://doi.org/10.3390/cancers13235925 |
PubMed ID | 34885036 |
Scopus EID | 2-s2.0-85119657022 |
PubMed Central ID | PMC8656540 |
Open access | Published as ‘gold’ (paid) open access |
Page range | 1-22 |
Funder | Australian New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) |
Research Training Program Scholarship (RTP), Australian Government | |
Freemasons Centre for Men’s Health | |
National Health and Medical Research Council (NHMRC) | |
Victorian Cancer Agency | |
Publisher's version | License File Access Level Open |
Output status | Published |
Publication dates | |
Online | 25 Nov 2021 |
Publication process dates | |
Accepted | 19 Nov 2021 |
Deposited | 28 Feb 2023 |
Grant ID | 1090517 |
MCRF19028 |
https://acuresearchbank.acu.edu.au/item/8yvq5/acceptability-and-preliminary-efficacy-of-a-web-and-telephone-based-personalised-exercise-intervention-for-individuals-with-metastatic-prostate-cancer-the-exercise-guide-pilot-randomised-controlled
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Publisher's version
OA_Evans_2021_Acceptability_and_preliminary_efficacy_of_a.pdf | |
License: CC BY 4.0 | |
File access level: Open |
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