Global, regional, and national burden of epilepsy, 1990–2016 : A systematic analysis for the Global Burden of Disease Study 2016

Journal article


Beghi, Ettore, Giussani, Giorgia, Nichols, Emma, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abraha, Haftom Niguse, Adib, Mina G., Agrawal, Sutapa, Alahdab, Fares, Awasthi, Ashish, Ayele, Yohanes, Barboza, Miguel A., Belachew, Abate Bekele, Biadgo, Belete, Bijani, Ali, Bitew, Helen, Carvalho, Félix, Chaiah, Yazan, ... Murray, Christopher J. L.. (2019). Global, regional, and national burden of epilepsy, 1990–2016 : A systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology. 18(4), pp. 357-375. https://doi.org/10.1016/S1474-4422(18)30454-X
AuthorsBeghi, Ettore, Giussani, Giorgia, Nichols, Emma, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abraha, Haftom Niguse, Adib, Mina G., Agrawal, Sutapa, Alahdab, Fares, Awasthi, Ashish, Ayele, Yohanes, Barboza, Miguel A., Belachew, Abate Bekele, Biadgo, Belete, Bijani, Ali, Bitew, Helen, Carvalho, Félix, Chaiah, Yazan, Daryani, Ahmad, Do, Huyen Phuc, Dubey, Manisha, Endries, Aman Yesuf Yesuf, Eskandarieh, Sharareh, Faro, Andre, Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Fijabi, Daniel Obadare, Filip, Irina, Fischer, Florian, Gebre, Abadi Kahsu, Tsadik, Afewerki Gebremeskel, Gebremichael, Teklu Gebrehiwo, Gezae, Kebede Embaye, Ghasemi-Kasman, Maryam, Weldegwergs, Kidu Gidey, Degefa, Meaza Girma, Gnedovskaya, Elena V., Hagos, Tekleberhan B., Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hassen, Hamid Yimam, Hay, Simon I., Jakovljevic, Mihajlo, Kasaeian, Amir, Kassa, Tesfaye Dessale, Khader, Yousef Saleh, Khalil, Ibrahim, Khan, Ejaz Ahmad, Khubchandani, Jagdish, Kisa, Adnan, Krohn, Kristopher J., Kulkarni, Chanda, Nirayo, Yirga Legesse, Mackay, Mark T., Majdan, Marek, Majeed, Azeem, Manhertz, Treh, Mehndiratta, Man Mohan, Mekonen, Tesfa, Meles, Hagazi Gebre, Mengistu, Getnet, Mohammed, Shafiu, Naghavi, Mohsen, Mokdad, Ali H., Mustafa, Ghulam, Irvani, Seyed Sina Naghibi, Nguyen, Long Hoang, Nixon, Molly R., Ogbo, Felix Akpojene, Olagunju, Andrew T., Olagunju, Tinuke O., Owolabi, Mayowa Ojo, Phillips, Michael R., Pinilla-Monsalve, Gabriel David, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rahimi-Movaghar, Vafa, Reinig, Nickolas, Sachdev, Perminder S., Safari, Hosein, Safari, Saeed, Safiri, Saeid, Sahraian, Mohammad Ali, Samy, Abdallah M., Sarvi, Shahabeddin, Sawhney, Monika, Shaikh, Masood A., Sharif, Mehdi, Singh, Gagandeep, Smith, Mari, Szoeke, Cassandra E. I., Tabarés-Seisdedos, Rafael, Temsah, Mohamad-Hani, Temsah, Omar, Tortajada-Girbés, Miguel, Tran, Bach Xuan, Tsegay, Amanuel Amanuel Tesfay, Ullah, Irfan, Venketasubramanian, Narayanaswamy, Westerman, Ronny, Winkler, Andrea Sylvia, Yimer, Ebrahim M., Yonemoto, Naohiro, Feigin, Valery L., Vos, Theo and Murray, Christopher J. L.
Abstract

Background
Seizures and their consequences contribute to the burden of epilepsy because they can cause health loss (premature mortality and residual disability). Data on the burden of epilepsy are needed for health-care planning and resource allocation. The aim of this study was to quantify health loss due to epilepsy by age, sex, year, and location using data from the Global Burden of Diseases, Injuries, and Risk Factors Study.

Methods
We assessed the burden of epilepsy in 195 countries and territories from 1990 to 2016. Burden was measured as deaths, prevalence, and disability-adjusted life-years (DALYs; a summary measure of health loss defined by the sum of years of life lost [YLLs] for premature mortality and years lived with disability), by age, sex, year, location, and Socio-demographic Index (SDI; a compound measure of income per capita, education, and fertility). Vital registrations and verbal autopsies provided information about deaths, and data on the prevalence and severity of epilepsy largely came from population representative surveys. All estimates were calculated with 95% uncertainty intervals (UIs).

Findings
In 2016, there were 45·9 million (95% UI 39·9–54·6) patients with all-active epilepsy (both idiopathic and secondary epilepsy globally; age-standardised prevalence 621·5 per 100 000 population; 540·1–737·0). Of these patients, 24·0 million (20·4–27·7) had active idiopathic epilepsy (prevalence 326·7 per 100 000 population; 278·4–378·1). Prevalence of active epilepsy increased with age, with peaks at 5–9 years (374·8 [280·1–490·0]) and at older than 80 years of age (545·1 [444·2–652·0]). Age-standardised prevalence of active idiopathic epilepsy was 329·3 per 100 000 population (280·3–381·2) in men and 318·9 per 100 000 population (271·1–369·4) in women, and was similar among SDI quintiles. Global age-standardised mortality rates of idiopathic epilepsy were 1·74 per 100 000 population (1·64–1·87; 1·40 per 100 000 population [1·23–1·54] for women and 2·09 per 100 000 population [1·96–2·25] for men). Age-standardised DALYs were 182·6 per 100 000 population (149·0–223·5; 163·6 per 100 000 population [130·6–204·3] for women and 201·2 per 100 000 population [166·9–241·4] for men). The higher DALY rates in men were due to higher YLL rates compared with women. Between 1990 and 2016, there was a non-significant 6·0% (−4·0 to 16·7) change in the age-standardised prevalence of idiopathic epilepsy, but a significant decrease in age-standardised mortality rates (24·5% [10·8 to 31·8]) and age-standardised DALY rates (19·4% [9·0 to 27·6]). A third of the difference in age-standardised DALY rates between low and high SDI quintile countries was due to the greater severity of epilepsy in low-income settings, and two-thirds were due to a higher YLL rate in low SDI countries.

Interpretation
Despite the decrease in the disease burden from 1990 to 2016, epilepsy is still an important cause of disability and mortality. Standardised collection of data on epilepsy in population representative surveys will strengthen the estimates, particularly in countries for which we currently have no or sparse data and if additional data is collected on severity, causes, and treatment. Sizeable gains in reducing the burden of epilepsy might be expected from improved access to existing treatments in low-income countries and from the development of new effective drugs worldwide.

Year2019
JournalThe Lancet Neurology
Journal citation18 (4), pp. 357-375
PublisherElsevier Ltd
ISSN1474-4465
1474-4422
Digital Object Identifier (DOI)https://doi.org/10.1016/S1474-4422(18)30454-X
PubMed ID30773428
Scopus EID2-s2.0-85062711685
PubMed Central IDPMC6416168
Open accessPublished as ‘gold’ (paid) open access
Page range357-375
FunderBill & Melinda Gates Foundation
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online14 Feb 2019
Publication process dates
Deposited21 Mar 2023
Permalink -

https://acuresearchbank.acu.edu.au/item/8yy16/global-regional-and-national-burden-of-epilepsy-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016

Download files


Publisher's version
OA_Ettore_2019_Global_regional_and_national_burden_of.pdf
License: CC BY 4.0
File access level: Open

  • 113
    total views
  • 33
    total downloads
  • 2
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Factors associated with improved walking in older people during hospital rehabilitation : Secondary analysis of a randomized controlled trial
Said, Catherine M., McGinley, Jennifer L., Szoeke, Cassandra, Workman, Barbara, Hill, Keith D., Wittwer, Joanne E., Woodward, Michael, Liew, Danny, Churilov, Leonid, Bernhardt, Julie and Morris, Meg E.. (2021). Factors associated with improved walking in older people during hospital rehabilitation : Secondary analysis of a randomized controlled trial. BMC Geriatrics. 21, p. Article 90. https://doi.org/10.1186/s12877-021-02016-0
Incidence, progression, and patterns of multimorbidity in community-dwelling middle-aged men and women
Shang, Xianwen, Peng, Wei, Hill, Hill, Szoeke, Cassandra, He, Mingguang and Zhang, Lei. (2020). Incidence, progression, and patterns of multimorbidity in community-dwelling middle-aged men and women. Frontiers in Public Health. 8(404), pp. 1-12. https://doi.org/10.3389/fpubh.2020.00404
Baseline white matter is associated with physical fitness change in preclinical Alzheimer’s disease
Venkatraman, Vijay K., Steward, Christopher E., Cox, Kay L., Ellis, Kathryn A., Phal, Pramit M., Sharman, Matthew J., Villemagne, Victor L., Lai, Michelle M. Y., Cyarto, Elizabeth V., Ames, David, Szoeke, Cassandra, Rowe, Christopher C., Masters, Colin L., Lautenschlager, Nicola T. and Desmond, Patricia M.. (2020). Baseline white matter is associated with physical fitness change in preclinical Alzheimer’s disease. Frontiers in Aging Neuroscience. 12, p. 115. https://doi.org/10.3389/fnagi.2020.00115
Global, regional, and national burden of neurological disorders, 1990–2016 : A systematic analysis for the Global Burden of Disease Study 2016
Feigin, Valery L., Nichols, Emma, Alam, Tahiya, Bannick, Marlena S., Beghi, Ettore, Blake, Natacha, Culpepper, William J., Dorsey, E. Ray, Elbaz, Alexis, Ellenbogen, Richard G., Fisher, James L., Fitzmaurice, Christina, Giussani, Giorgia, Glennie, Linda, James, Spencer L., Johnson, Catherine Owens, Kassebaum, Nicholas J., Logroscino, Giancarlo, Marin, Benoît, ... Vos, Theo. (2019). Global, regional, and national burden of neurological disorders, 1990–2016 : A systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology. 18(5), pp. 459-480. https://doi.org/10.1016/S1474-4422(18)30499-X
Incidence of medication-treated depression and anxiety associated with long-term cancer, cardiovascular disease, diabetes and osteoarthritis in community-dwelling women and men
Shang, Xianwen, Peng, Wei, Hill, Edward, Szoeke, Cassandra, He, Mingguang and Zhang, Lei. (2019). Incidence of medication-treated depression and anxiety associated with long-term cancer, cardiovascular disease, diabetes and osteoarthritis in community-dwelling women and men. EClinicalMedicine. 15, pp. 23-32. https://doi.org/10.1016/j.eclinm.2019.08.010
Association between structural changes in brain with muscle function in sarcopenic older women : The Women’s Healthy Ageing Project (WHAP)
Hassan, Ebrahim Bani, Szoeke, Cassandra, Vogrin, Sara, Phu, Steven, Venkatraman, Vijay, Desmond, Patricia, Steward, Chris and Duque, Gustavo. (2019). Association between structural changes in brain with muscle function in sarcopenic older women : The Women’s Healthy Ageing Project (WHAP). The Journal of Musculoskeletal and Neuronal Interactions. 19(2), pp. 136-141.
A randomized controlled trial of adherence to a 24-month home-based physical activity program and the health benefits for older adults at risk of Alzheimer's Disease : The AIBL Active-Study
Cox, Kay L., Cyarto, Elizabeth V., Ellis, Kathryn A., Ames, David, Desmond, Patricia, Phal, Pramit, Sharman, Matthew J., Szoeke, Cassandra, Rowe, Christopher C., Masters, Colin L., You, Emily, Burrows, Sally, Lai, Michelle M. Y. and Lautenschlager, Nicola T.. (2019). A randomized controlled trial of adherence to a 24-month home-based physical activity program and the health benefits for older adults at risk of Alzheimer's Disease : The AIBL Active-Study. Journal of Alzheimer's Disease. 70(s1), pp. S187-S205. https://doi.org/10.3233/JAD-180521
Diet and biomarkers of Alzheimer's disease : A systematic review and meta-analysis
Hill, Edward, Goodwill, Alicia M., Gorelik, Alexandra and Szoeke, Cassandra. (2019). Diet and biomarkers of Alzheimer's disease : A systematic review and meta-analysis. Neurobiology of Aging. 76, pp. 45-52. https://doi.org/10.1016/j.neurobiolaging.2018.12.008
A decade of changes in brain volume and cognition
Aljondi, Rowa, Szoeke, Cassandra, Steward, Chris, Yates, Paul and Desmond, Patricia. (2019). A decade of changes in brain volume and cognition. Brain Imaging and Behavior. 13(2), pp. 554-563. https://doi.org/10.1007/s11682-018-9887-z
Robust norms for neuropsychological tests of verbal episodic memory in Australian women
Goodwill, Alicia, Campbell, Stephen, Henderson, Victor W., Gorelik, Alexandra, Dennerstein, Lorraine, McClung, Michael and Szoeke, Cassandra. (2019). Robust norms for neuropsychological tests of verbal episodic memory in Australian women. Neuropsychology. 33(4), pp. 581 - 595. https://doi.org/10.1037/neu0000522
Do replicable profiles of multimorbidity exist? Systematic review and synthesis
Busija, Ljoudmila, Lim, Karen, Szoeke, Cassandra, Sanders, Kerrie M. and McCabe, Marita P.. (2019). Do replicable profiles of multimorbidity exist? Systematic review and synthesis. European Journal of Epidemiology. 34, pp. 1025 - 1053. https://doi.org/10.1007/s10654-019-00568-5
Apolipoprotein E4 mediates the association between midlife dyslipidemia and cerebral amyloid in aging women
Szoeke, Cassandra, Goodwill, Alicia M., Gorelik, Alexandra, Dennerstein, Lorraine, Caeyenberghs, Karen, Simpson, Steve, Hill, Edward and Campbell, Stephen. (2019). Apolipoprotein E4 mediates the association between midlife dyslipidemia and cerebral amyloid in aging women. Journal of Alzheimer's Disease. 68(1), pp. 105 - 114. https://doi.org/10.3233/JAD-180815
Global, regional, and national burden of Parkinson's disease, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016
Dorsey, E. Ray, Elbaz, Alexis, Nichols, Emma, Abd-Allah, Foad, Abdelalim, Ahmed, Adsuar, Jose C., Ansha, Mustafa Geleto, Brayne, Carol, Choi, Jee-Young J., Collado-Mateo, Daniel, Dahodwala, Nabila, Do, Huyen Phuc, Edessa, Dumessa, Endres, Matthias, Fereshtehnejad, Seyed-Mohammad, Foreman, Kyle J., Gankpe, Fortune Gbetoho, Gupta, Rahul, Hankey, Graeme J., ... Murray, Christopher J. L.. (2018). Global, regional, and national burden of Parkinson's disease, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology. 17(11), pp. 939 - 953. https://doi.org/10.1016/S1474-4422(18)30295-3
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017
GBD 2017 DALYs and HALE Collaborators, , Kyu, Hmwe Hmwe, Abate, Degu, Abate, Kalkidan Hassen, Abay, Solomon M., Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Molla, Abebe, Zegeye, Abil, Olifan Zewdie, Aboyans, Victor, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, ... GBD 2017 DALYs and HALE Collaborators. (2018). Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 392(10159), pp. 1859 - 1922. https://doi.org/10.1016/S0140-6736(18)32335-3
Measuring performance on the healthcare access and quality index for 195 countries and territories and selected subnational locations: a systematic analysis from the global burden of disease study 2016
Fullman, Nancy, Yearwood, Jamal, Abay, Solomon M., Abbafati, Cristiana, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abebe, Zegeye, Abebo, Teshome Abuka, Aboyans, Victor, Abraha, Haftom Niguse, Abreu, Daisy M. X., Abu-Raddad, Laith J., Adane, Akilew Awoke, Adedoyin, Rufus Adesoji, Adetokunboh, Olatunji, Adhikari, Tara Ballav, Afarideh, Mohsen, Afshin, Ashkan, ... Lozano, Rafael. (2018). Measuring performance on the healthcare access and quality index for 195 countries and territories and selected subnational locations: a systematic analysis from the global burden of disease study 2016. The Lancet. 391(10136), pp. 2236 - 2271. https://doi.org/10.1016/S0140-6736(18)30994-2
Global, regional, and national burden of migraine and tension-type headache, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016
Stovner, Lars Jacob, Nichols, Emma, Steiner, Timothy J., Abd-Allah, Foad, Abdelalim, Ahmed, Al-Raddadi, Rajaa, Ansha, Mustafa Geleto, Barac, Aleksandra, Bensenor, Isabela M., Doan, Linh Phuong, Edessa, Dumessa, Endres, Matthias, Foreman, Kyle J., Gankpe, Fortune Gbetoho, Gopalkrishna, Gururaj, Goulart, Alessandra Carvalho, Gupta, Rahul, Hankey, Graeme J., Hay, Simon I., ... Murray, Christopher J. L.. (2018). Global, regional, and national burden of migraine and tension-type headache, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology. 17(11), pp. 954 - 976. https://doi.org/10.1016/S1474-4422(18)30322-3
Additional structured physical activity does not improve walking in older people (60 years) undergoing inpatient rehabilitation: A randomised trial
Said, Catherine M., Morris, Meg E., McGinley, Jennifer L., Szoeke, Cassandra, Workman, Barbara, Liew, Danny, Hill, Keith D., Woodward, Michael Clifford, Wittwer, Joanne E., Churilov, Leonid, Danoudis, Mary and Bernhardt, Julie. (2018). Additional structured physical activity does not improve walking in older people (60 years) undergoing inpatient rehabilitation: A randomised trial. Journal of Physiotherapy. 64(4), pp. 237 - 244. https://doi.org/10.1016/j.jphys.2018.08.006
Vitamin D status is associated with executive function a decade later: Data from the Women's Healthy Ageing Project
Goodwill, Alicia M., Campbell, Stephen, Simpson, Steve, Bisignano, Maria, Chiang, Cherie Y., Dennerstein, Lorraine and Szoeke, Cassandra. (2018). Vitamin D status is associated with executive function a decade later: Data from the Women's Healthy Ageing Project. Maturitas. 107, pp. 56 - 62. https://doi.org/10.1016/j.maturitas.2017.10.005
Self-reported confusion is related to global and regional ß-amyloid: data from the Women's healthy ageing project
McCluskey, Georgia E., Yates, Patsy, Villemagne, Victor L., Rowe, Christopher C. and Szoeke, Cassandra. (2018). Self-reported confusion is related to global and regional ß-amyloid: data from the Women's healthy ageing project. Brain Imaging and Behavior: an international journal. 12(1), pp. 78 - 86. https://doi.org/10.1007/s11682-016-9668-5
Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990–2015: Findings from the Global Burden of Disease 2015 Study
Tehrani-Banihashemi, Arash, Moradi-Lakeh, Maziar, Bcheraoui, Charbel El, Charara, Raghid, Khalil, Ibrahim, Afshin, Ashkan, Collison, Michael, Daoud, Farah, Krohn, Kristopher J., Chew, Adrienne, Cornaby, Leslie, Foreman, Kyle J., Frostad, Joseph J., Kassebaum, Nicholas J., Kemmer, Laura, Kutz, Michael, Liu, Patrick, Mirarefin, Mojde, Nguyen, Grant, ... Szoeke, Cassandra. (2018). Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990–2015: Findings from the Global Burden of Disease 2015 Study. International Journal of Public Health. 63, pp. 137 - 149. https://doi.org/10.1007/s00038-017-1012-3
Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: A systematic analysis from the global burden of disease study 2015
Reitsma, Marissa B., Fullman, Nancy, Ng, M., Salama, Joseph S., Abajobir, A. A., Abate, K. H., Abbafati, Cristiana, Abera, Semaw F., Abraham, B., Abyu, Gebre Yitayih, Adebiyi, Akindele Olupelumi, Mumford, J. E., Aleman, Alicia V., Ali, Raghib, Alkerwi, Ala'a, Allebeck, Peter, Al-Raddadi, Rajaa, Amare, Azmeraw T., Amberbir, A., ... Szoeke, Cassandra EI. (2017). Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: A systematic analysis from the global burden of disease study 2015. The Lancet. 389(10082), pp. 1885 - 1906. https://doi.org/10.1016/S0140-6736(17)30819-X
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016
GBD 2016 Risk Factors Collaborators, , Gakidou, Emmanuela, Afshin, Ashkan, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abdulle, Abdishakur M., Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen M. E., Abyu, Gebre Yitayih, Adedeji, Isaac Akinkunmi, Adetokunboh, Olatunji, Afarideh, Mohsen, Agrawal, Anurag, Agrawal, Sutapa, ... GBD 2016 Risk Factors Collaborators. (2017). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 390(10100), pp. 1345 - 1422. https://doi.org/10.1016/S0140-6736(17)32366-8
Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Feigin, Valery L., Krishnamurthi, Rita, Theadom, Alice M., Abajobir, A. A., Mishra, Shiva Raj, Ahmed, Muktar Beshir, Abate, K. H., Mengistie, Mubarek Abera, Wakayo, Tolassa, Abd-Allah, Foad, Abdulle, Abdishakur M., Abera, Semaw F., Mohammed, Kedir Endris, Abyu, Gebre Yitayih, Asgedom, Solomon Weldegebreal, Atey, Tesfay Mehari, Betsu, Balem Demtsu, Mezgebe, Haftay Berhane, Tuem, Kald Beshir, ... Szoeke, Cassandra EI. (2017). Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet Neurology. 16(11), pp. 877 - 897. https://doi.org/10.1016/S1474-4422(17)30299-5
Unhealthy habits persist: The ongoing presence of modifiable risk factors for disease in women
Szoeke, Cassandra, Dang, Christa, Lehert, Philippe, Hickey, Martha, Morris, Meg E., Dennerstein, Lorraine and Campbell, Stephen. (2017). Unhealthy habits persist: The ongoing presence of modifiable risk factors for disease in women. PLoS ONE. 12(7), pp. 1 - 16. https://doi.org/10.1371/journal.pone.0173603
A systematic review and meta-analysis of the effect of low vitamin D on cognition
Goodwill, Marie A. and Szoeke, Cassandra. (2017). A systematic review and meta-analysis of the effect of low vitamin D on cognition. Journal of the American Geriatrics Society. 65(10), pp. 2161 - 2168. https://doi.org/10.1111/jgs.15012
The trajectory of negative mood and depressive symptoms over two decades
Campbell, Katherine E., Dennerstein, Lorraine, Tacey, Mark and Szoeke, Cassandra E.. (2017). The trajectory of negative mood and depressive symptoms over two decades. Maturitas. https://doi.org/10.1016/j.maturitas.2016.10.011
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016
GBD 2016 Mortality Collaborators,, Wang, Haidong, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abera, Semaw Ferede, Abraha, Haftom Niguse, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen M. E., Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adetifa, Ifedayo Morayo O., Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Anurag, Agrawal, Sutapa, ... GBD 2016 Mortality Collaborators. (2017). Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 390(10100), pp. 1084 - 1150. https://doi.org/10.1016/S0140-6736(17)31833-0
Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016
GBD 2016 DALYs and HALE Collaborators, , Hay, Simon I., Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abdulle, Abdishakur M., Abebo, Teshome Abuka, Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J., Ackerman, Ilana N., Adedeji, Isaac Akinkunmi, Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Sutapa, Agrawal, Anurag, ... GBD 2016 DALYs and HALE Collaborators. (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 390(10100), pp. 1260 - 1344. https://doi.org/10.1016/S0140-6736(17)32130-X
A Systematic Review and Meta-Analysis of The Effect of Low Vitamin D on Cognition
Goodwill, Marie A. and Szoeke, Cassandra. (2017). A Systematic Review and Meta-Analysis of The Effect of Low Vitamin D on Cognition. Journal of the American Geriatrics Society. 65(10), pp. 2161 - 2168. https://doi.org/10.1111/jgs.15012
Measuring progress and projecting attainment on the basis of past trends of the health-related sustainable development goals in 188 countries: An analysis from the Global Burden of Disease Study 2016
GBD 2016 SDG Collaborators, , Fullman, Nancy, Barber, Ryan M., Abajobir, Amanuel A., Abate, Kalkidan H., Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abdulle, Abdishakur M., Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen M. E., Adedeji, Isaac Akinkunmi, Adetokunboh, Olatunji, Afshin, Ashkan, Agrawal, Anurag, Agrawal, Sutapa, Kiadaliri, Aliasghar Ahmad, ... GBD 2016 SDG Collaborators. (2017). Measuring progress and projecting attainment on the basis of past trends of the health-related sustainable development goals in 188 countries: An analysis from the Global Burden of Disease Study 2016. The Lancet. 390(10100), pp. 1423 - 1459. https://doi.org/10.1016/S0140-6736(17)32336-X
Gender, marital status and longevity
Tatangelo, Gemma, McCabe, Marita, Campbell, Stephen and Szoeke, Cassandra. (2017). Gender, marital status and longevity. Maturitas. 100, pp. 64 - 69. https://doi.org/10.1016/j.maturitas.2017.03.002
A comparison of Geriatric Depression Scale scores in older Australian and Japanese women
Campbell, Katherine E., Dennerstein, Lorraine, Tacey, Mark, Fujise, Noboru, Ikeda, Manabu and Szoeke, Cassandra. (2017). A comparison of Geriatric Depression Scale scores in older Australian and Japanese women. Epidemiology and Psychiatric Sciences. https://doi.org/10.1017/S2045796015001110
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015
Forouzanfar, Mohammad H., Afshin, Ashkan, Alexander, Lily T., Anderson, H. Ross, Bhutta, Zulfiqar A., Biryukov, Stan, Brauer, Michael, Burnett, Richard, Cercy, Kelly, Charlson, Fiona J., Cohen, Aaron J., Dandona, Lalit, Estep, Kara, Ferrari, Alize J., Frostad, Joseph J., Fullman, Nancy, Gething, Peter W., Godwin, William W., Griswold, Max, ... GBD 2015 Risk Factors Collaborators. (2016). Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1659 - 1724. https://doi.org/10.1016/S0140-6736(16)31679-8
Measuring the health-related sustainable development goals in 188 countries: A baseline analysis from the Global Burden of Disease Study 2015
Lim, Stephen S., Allen, Kate, Bhutta, Zulfiqar A., Dandona, Lalit, Forouzanfar, Mohammad H., Fullman, Nancy, Gething, Peter W., Goldberg, Ellen M., Hay, Simon I., Holmberg, Mollie, Kinfu, Yohannes, Kutz, Michael J., Larson, Heidi J., Liang, Xiaofeng, Lopez, Alan D., Lozano, Rafael, McNellan, Claire R., Mokdad, Ali H., Mooney, Meghan D., ... GBD 2015 SDG Collaborators. (2016). Measuring the health-related sustainable development goals in 188 countries: A baseline analysis from the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1813 - 1850. https://doi.org/10.1016/S0140-6736(16)31467-2
Patterns of social engagement in the transition to later life
Burn, Katherine F., Dennerstein, Lorraine, Browning, Colette and Szoeke, Cassandra. (2016). Patterns of social engagement in the transition to later life. Maturitas. 88(June), pp. 90 - 95. https://doi.org/10.1016/j.maturitas.2016.03.016
Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015
Kassebaum, Nicholas J., Arora, Megha, Barber, Ryan M., Bhutta, Zulfiqar A., Brown, Jonathan, Carter, Austin, Casey, Daniel C., Charlson, Fiona J., Coates, Matthew M., Coggeshall, Megan, Cornaby, Leslie, Dandona, Lalit, Dicker, Daniel J., Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Foreman, Kyle, Forouzanfar, Mohammad H., Fullman, Nancy, ... HALE Collaborators. (2016). Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1603 - 1658. https://doi.org/10.1016/S0140-6736(16)31460-X
Boomerang families and failure-to-launch: Commentary On adult children living at home
Burn, Katherine F. and Szoeke, Cassandra. (2016). Boomerang families and failure-to-launch: Commentary On adult children living at home. Maturitas. 83, pp. 9 - 12. https://doi.org/10.1016/j.maturitas.2015.09.004
Predictive Factors for Verbal Memory Performance Over Decades of Aging: Data from the Women's Healthy Ageing Project
Szoeke, Cassandra, Lehert, Philippe, Henderson, Victor W., Dennerstein, Lorraine, Desmond, Patricia and Campbell, Stephen. (2016). Predictive Factors for Verbal Memory Performance Over Decades of Aging: Data from the Women's Healthy Ageing Project. American Journal of Geriatric Psychiatry. https://doi.org/10.1016/j.jagp.2016.05.008
High content, multi-parameter analyses in buccal cells to identify Alzheimer's Disease
François, Maxime, Fenech, Michael F., Thomas, Philip, Hor, Maryam, Savage, Greg, Martins, Ralph N., Rainey-Smith, Stephanie R., Masters, Colin L., Ames, David, Rowe, Christopher C., Macaulay, Stuart Lance, Hill, Andrew F., Leifert, Wayne R., Appannah, Arti, Barnes, Margaret, Barnham, K. J., Bedo, Justin, Bellingham, Shayne, Bon, Lynette, ... Szoeke, Cassandra. (2016). High content, multi-parameter analyses in buccal cells to identify Alzheimer's Disease. Current Alzheimer Research. 13(7), pp. 787 - 799.
Global, regional, and national levels of maternal mortality, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015
Kassebaum, Nicholas J., Barber, Ryan M., Bhutta, Zulfiqar A., Dandona, Lalit, Gething, Peter W., Hay, Simon I., Kinfu, Yohannes, Larson, Heidi J., Liang, Xiaofeng, Lim, Stephen S., Lopez, Alan D., Lozano, Rafael, Mensah, George A., Mokdad, Ali H., Naghavi, Mohsen, Pinho, Christine, Salomon, Joshua A., Steiner, Caitlyn, Vos, Theo, ... GBD 2015 Maternal Mortality Collaborators. (2016). Global, regional, and national levels of maternal mortality, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1775 - 1812. https://doi.org/10.1016/S0140-6736(16)31470-2
Patterns of social engagement in the transition to later life
Burn, Katherine F., Dennerstein, Lorraine, Browning, Colette and Szoeke, Cassandra. (2016). Patterns of social engagement in the transition to later life. Maturitas. https://doi.org/10.1016/j.maturitas.2016.03.016
Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: A systematic analysis for the Global Burden of Disease Study 2015
Wang, Haidong, Bhutta, Zulfiqar A., Coates, Matthew M., Coggeshall, Megan, Dandona, Lalit, Diallo, Khassoum, Franca, Elisabeth Barboza, Fraser, Maya, Fullman, Nancy, Gething, Peter W., Hay, Simon I., Kinfu, Yohannes, Kita, Maaya, Kulikoff, Xie Rachel, Larson, Heidi J., Liang, Juan, Lim, Stephen S., Lind, Margaret, Lopez, Alan D., ... GBD 2015 Child Mortality Collaborators. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: A systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1725 - 1774. https://doi.org/10.1016/S0140-6736(16)31575-6
The impact of red and processed meat consumption on cardiovascular disease risk in women
Bovalino, Stephen, Charleson, Georgia and Szoeke, Cassandra. (2016). The impact of red and processed meat consumption on cardiovascular disease risk in women. Nutrition. 32(3), pp. 349 - 354. https://doi.org/10.1016/j.nut.2015.09.015
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: A systematic analysis for the Global Burden of Disease Study 2015
Wang, Haidong, Naghavi, Mohsen, Allen, Christine, Barber, Ryan M., Bhutta, Zulfiqar A., Carter, Austin, Casey, Daniel C., Charlson, Fiona J., Chen, Alan Zian, Coates, Matthew M., Coggeshall, Megan, Dandona, Lalit, Dicker, Daniel J., Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Foreman, Kyle, Forouzanfar, Mohammad H., Fraser, Maya S., ... GBD 2015 Mortality and Causes of Death Collaborators. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: A systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1459 - 1544. https://doi.org/10.1016/S0140-6736(16)31012-1
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990--2015: a systematic analysis for the Global Burden of Disease Study 2015
Vos, Theo, Allen, Christine, Arora, Megha, Barber, Ryan M., Bhutta, Zulfiqar A., Brown, Alexandria, Carter, Austin, Casey, Daniel C., Charlson, Fiona J., Chen, Alan Z., Coggeshall, Megan, Cornaby, Leslie, Dandona, Lalit, Dicker, Daniel J., Dilegge, Tina, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Tom, ... Murray, Christopher J. L.. (2016). Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990--2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388(10053), pp. 1545 - 1602. https://doi.org/10.1016/S0140-6736(16)31678-6
Phenomenological characterization of memory complaints in preclinical and prodromal Alzheimer's disease
Buckley, Rachel F., Ellis, Kathryn A., Ames, David, Rowe, Christopher C., Lautenschlager, Nicola T., Maruff, Paul Thomas, Villemagne, Victor L., Macaulay, S. Lance, Szoeke, Cassandra, Martins, Ralph N., Masters, Colin L., Savage, Greg, Rainey-Smith, Stephanie R., Rembach, Alan R. and Saling, Michael M.. (2015). Phenomenological characterization of memory complaints in preclinical and prodromal Alzheimer's disease. Neuropsychology. https://doi.org/10.1037/neu0000156
Grandparenting predicts late-life cognition: Results from the Women's Healthy Ageing Project
Burn, Katherine F. and Szoeke, Cassandra. (2015). Grandparenting predicts late-life cognition: Results from the Women's Healthy Ageing Project. Maturitas. https://doi.org/10.1016/j.maturitas.2015.03.013
Longitudinal cognitive decline in the AIBL cohort: The role of APOE E4 status
Albrecht, Matthew A., Szoeke, Cassandra, Maruff, Paul Thomas, Savage, Greg, Lautenschlager, Nicola T., Ellis, Kathryn A., Taddei, Kevin, Martins, Ralph N., Masters, Colin L., Ames, David and Foster, Jonathan K.. (2015). Longitudinal cognitive decline in the AIBL cohort: The role of APOE E4 status. Neuropsychologia. https://doi.org/10.1016/j.jalz.2014.04.303
Evaluating the effects of increasing physical activity to optimize rehabilitation outcomes in hospitalized older adults (MOVE Trial): Study protocol for a randomized controlled trial
Said, Catherine M., Morris, Meg E., McGinley, Jennifer L., Szoeke, Cassandra, Workman, Barbara, Liew, Danny, Hill, Keith David, Woodward, Michael Clifford, Wittwer, Joanne E., Churilov, Leonid, Ventura, Cameron and Bernhardt, Julie. (2015). Evaluating the effects of increasing physical activity to optimize rehabilitation outcomes in hospitalized older adults (MOVE Trial): Study protocol for a randomized controlled trial. Trials. 16(1), pp. 1 - 9. https://doi.org/10.1186/s13063-014-0531-y
Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease
Kerestes, Rebecca, Phal, Pramit M., Steward, Chris, Moffat, Bradford A., Salinas, Simon, Cox, Kay L., Ellis, Kathryn A., Cyarto, Elizabeth V., Ames, David, Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Sharman, Matthew J., Salvado, Oliver, Szoeke, Cassandra, Lai, Michelle, Lautenschlager, Nicola T. and Desmond, Patricia M.. (2015). Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease. BJPsych Open. 1(2), pp. 139 - 148. https://doi.org/10.1192/bjpo.bp.115.001339
Is grandparenting a form of social engagement that benefits cognition in ageing?
Burn, Katherine F. and Szoeke, Cassandra. (2015). Is grandparenting a form of social engagement that benefits cognition in ageing? Maturitas. 80(2), pp. 122 - 125. https://doi.org/10.1016/j.maturitas.2014.10.017
Semi-automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration
Merkel, Bernd, Steward, Christopher, Vivash, Lucy, Malpas, Charles B., Phal, Pramit, Moffat, Bradford A., Cox, Kay L., Ellis, Kathryn A., Ames, David J., Cyarto, Elizabeth V., Lai, Michelle M. Y., Sharman, Matthew J., Szoeke, Cassandra, Masters, Colin L., Lautenschlager, Nicola T. and Desmond, Patricia. (2015). Semi-automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration. Journal of Magnetic Resonance Imaging. https://doi.org/10.1002/jmri.24966
Dietary patterns and cognitive decline in an Australian study of ageing
Gardener, S. L., Rainey-Smith, Stephanie R., Barnes, Margaret, Sohrabi, H. R., Weinborn, M., Lim, Yen Ying, Harrington, Karra D., Taddei, Kevin, Gu, Yian, Rembach, Alan R., Szoeke, Cassandra, Ellis, Kathryn A., Masters, C. L., Macaulay, Stuart Lance, Rowe, Christopher C., Ames, David, Keogh, Jennifer B., Scarmeas, Nikolaos and Martins, Ralph N.. (2015). Dietary patterns and cognitive decline in an Australian study of ageing. Molecular Psychiatry. https://doi.org/10.1038/mp.2014.79
Prehypertension in midlife is associated with worse cognition a decade later in middle-aged and older women
Chen, Karen, Henderson, Victor, Stolwyk, Rene, Dennerstein, Lorraine and Szoeke, Cassandra. (2015). Prehypertension in midlife is associated with worse cognition a decade later in middle-aged and older women. Age and Ageing. https://doi.org/10.1093/ageing/afv026
Anxiety symptoms, cerebral amyloid burden and memory decline in healthy older adults without dementia: 3-year prospective cohort study
Pietrzak, Robert H., Scott, James, Neumeister, Alexander, Lim, Yen Ying, Ames, David, Ellis, Kathryn A., Harrington, Karra D., Lautenschlager, Nicola T., Szoeke, Cassandra, Martins, Ralph N., Masters, Colin L., Villemagne, Victor L., Rowe, Christopher C. and Maruff, Paul Thomas. (2014). Anxiety symptoms, cerebral amyloid burden and memory decline in healthy older adults without dementia: 3-year prospective cohort study. British Journal of Psychiatry. https://doi.org/10.1192/bjp.bp.113.134239
Rates of diagnostic transition and cognitive change at 18-month follow-up among 1,112 participants in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL)
Ellis, Kathryn A., Szoeke, Cassandra, Bush, Ashley I., Darby, David, Graham, Petra, Lautenschlager, Nicola T., Macaulay, S Lance, Martins, Ralph N., Maruff, Paul Thomas, Masters, Colin L., McBride, Simon J., Pike, Kerryn E., Rainey-Smith, Stephanie R., Rembach, Alan R., Robertson, Joanne, Rowe, Christopher C., Savage, Greg, Villemagne, Victor L., Woodward, Michael Clifford, ... Ames, David. (2014). Rates of diagnostic transition and cognitive change at 18-month follow-up among 1,112 participants in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL). International Psychogeriatrics. https://doi.org/10.1017/S1041610213001956
Aß and cognitive change: Examining the preclinical and prodromal stages of Alzheimer's disease
Lim, Yen Ying, Maruff, Paul Thomas, Pietrzak, Robert H., Ellis, Kathryn A., Darby, David, -, David Ames, Harrington, Karra J., Martins, Ralph N., Masters, Colin L., Szoeke, Cassandra, Savage, Greg, Villemagne, Victor L. and Rowe, Christopher C.. (2014). Aß and cognitive change: Examining the preclinical and prodromal stages of Alzheimer's disease. Alzheimer's and Dementia. https://doi.org/10.1016/j.jalz.2013.11.005
Incidence of cerebral microbleeds in preclinical Alzheimer disease
Yates, Paul A., Desmond, Patricia M., Phal, Pramit M., Steward, Christopher, Szoeke, Cassandra, Salvado, Olivier, Ellis, Kathryn A., Martins, Ralph N., Masters, Colin L., Ames, David, Villemagne, Victor L. and Rowe, Christopher C.. (2014). Incidence of cerebral microbleeds in preclinical Alzheimer disease. Neurology. https://doi.org/10.1212/WNL.0000000000000285
Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: Combined data from three cohorts
Moore, Eileen, Ames, David, Mander, Alastair, Carne, Ross, Brodaty, Henry, Woodward, Michael Clifford, Boundy, Karen, Ellis, Kathryn A., Bush, Ashley I., Faux, Noel G., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Szoeke, Cassandra and Watters, David. (2014). Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: Combined data from three cohorts. Journal of Alzheimer's Disease. https://doi.org/10.3233/JAD-131265
Associations between gonadotropins, testosterone and ß amyloid in men at risk of Alzheimer's disease
Verdile, G., Laws, S. M., Henley, D., Ames, David, Bush, A. I., Ellis, Kathryn A., Faux, N. G., Gupta, V. B., Li, Q., Masters, C L., Pike, K E., Rowe, C. C., Szoeke, Cassandra, Taddei, K., Villemagne, V. L. and Martins, R. N.. (2014). Associations between gonadotropins, testosterone and ß amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry. https://doi.org/10.1038/mp.2012.147
Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease
Lim, Yen Ying, Maruff, Paul Thomas, Pietrzak, Robert H., Ames, David, Ellis, Kathryn A., Harrington, Karra J., Lautenschlager, Nicola T., Szoeke, Cassandra, Martins, Ralph N., Masters, Colin L., Villemagne, Victor L. and Rowe, Christopher C.. (2014). Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease. Brain. 137(1), pp. 221 - 231. https://doi.org/10.1093/brain/awt286
Autobiographical narratives relate to Alzheimer's disease biomarkers in older adults
Buckley, Rachel F., Saling, Michael M., Irish, Muireann, Ames, David, Rowe, Christopher C., Villemagne, Victor L., Lautenschlager, Nicola T., Maruff, Paul Thomas, Macaulay, S Lance, Martins, Ralph N., Szoeke, Cassandra, Masters, Colin L., Rainey-Smith, Stephanie R., Rembach, Alan R., Savage, Greg and Ellis, Kathryn A.. (2014). Autobiographical narratives relate to Alzheimer's disease biomarkers in older adults. International Psychogeriatrics. https://doi.org/10.1017/S1041610214001136
Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease
Rembach, Alan R., Gaux, Noel G., Watt, Andrew D., Pertile, Kelly Kathleen, Rumble, Rebecca L., Trounson, Brett O., Fowler, Christopher J., Roberts, Blaine R., Perez, Keyla A., Li, Qiaoxin, Laws, Simon M., Taddei, Kevin, Rainey-Smith, Stephanie R., Robertson, Joanne, Vandijck, Manu LJ, Vanderstichele, Hugo M. J., Barnham, Kevin Jeffrey, Ellis, Kathryn A., Szoeke, Cassandra, ... Masters, Colin L.. (2014). Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimer's and Dementia. https://doi.org/10.1016/j.jalz.2012.12.006
Genetic algorithm with logistic regression for prediction of progression to Alzheimer's disease
Johnson, Piers, Vandewater, Luke, Wilson, William, Maruff, Paul Thomas, Savage, Greg, Graham, Petra, Macaulay, Lance S., Ellis, Kathryn A., Szoeke, Cassandra, Martins, Ralph N., Rowe, Christopher C., Masters, Colin L., Ames, David and Zhang, Ping. (2014). Genetic algorithm with logistic regression for prediction of progression to Alzheimer's disease. BMC Bioinformatics. 15(S11), pp. 1 - 14. https://doi.org/10.1186/1471-2105-15-S16-S11
Dehydroepiandrosterone sulfate and cognition in midlife, post-menopausal women
Chua, Catherine K.Z., Henderson, Victor W., Dennerstein, Lorraine, Ames, David and Szoeke, Cassandra. (2014). Dehydroepiandrosterone sulfate and cognition in midlife, post-menopausal women. Neurobiology of Aging. 35(7), pp. 1654 - 1655. https://doi.org/10.1016/j.neurobiolaging.2014.01.140
The Women's Healthy Ageing Project: Fertile ground for investigation of healthy participants 'at risk' for dementia
Szoeke, Cassandra, Robertson, Joanne, Rowe, Christopher C., Yates, Paul A., Campbell, Katherine, Masters, C. L., Ames, David, Dennerstein, L. and Desmond, P.. (2013). The Women's Healthy Ageing Project: Fertile ground for investigation of healthy participants 'at risk' for dementia. International Review of Psychiatry. https://doi.org/10.3109/09540261.2013.873394
Lack of reliable evidence for a distinctive e4-related cognitive phenotype that is independent from clinical diagnostic status: Findings from the Australian Imaging, Biomarkers and Lifestyle Study
Foster, Jonathan, Albrecht, Matthew A., Savage, Greg, Lautenschlager, Nicola T., Ellis, Kathryn A., Maruff, Paul Thomas, Szoeke, Cassandra, Taddei, Kevin, Martins, Ralph N., Masters, Colin L. and Ames, David. (2013). Lack of reliable evidence for a distinctive e4-related cognitive phenotype that is independent from clinical diagnostic status: Findings from the Australian Imaging, Biomarkers and Lifestyle Study. Brain. https://doi.org/10.1093/brain/awt127
Aß amyloid, cognition, and APOE genotype in healthy older adults
Lim, Yen Ying, Ellis, Kathryn A., Ames, David, Darby, David, Harrington, Karra J., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Savage, Greg, Szoeke, Cassandra, Villemagne, Victor L. and Maruff, Paul Thomas. (2013). Aß amyloid, cognition, and APOE genotype in healthy older adults. Alzheimer's and Dementia. https://doi.org/10.1016/j.jalz.2012.07.004
Physical activity and amyloid-Beta plasma and brain levels: Results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing
Brown, Belinda M., Peiffer, J. J., Taddei, Kevin, Lui, J. K., Laws, Simon M., Gupta, V. B., Taddei, Tania, Ward, Vanessa K., Rodrigues, Mark A., Burnham, Samantha, Rainey-Smith, Stephanie R., Villemagne, Victor L., Bush, Ashley I., Ellis, Kathryn A., Masters, Colin L., Ames, David, Macaulay, S. Lance, Szoeke, Cassandra, Rowe, Christopher C. and Martins, Ralph N.. (2013). Physical activity and amyloid-Beta plasma and brain levels: Results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry. https://doi.org/10.1038/mp.2012.107
Retinal vascular biomarkers for early detection and monitoring of Alzheimer's disease
Frost, Shaun M., Kanagasinam, Yogesan, Sohrabi, Hamid R., Vignarajan, Janardhan, Bourgeat, Pierrick T., Salvado, Oliver, Villemagne, Victor Luis, Rowe, Christopher C., Macaulay, S. Lance, Szoeke, Cassandra, Ellis, Kathryn A., Ames, David, Masters, Colin L., Rainey-Smith, Stephanie R. and Martins, Ralph N.. (2013). Retinal vascular biomarkers for early detection and monitoring of Alzheimer's disease. Translational Psychiatry. https://doi.org/10.1038/tp.2012.150
Normative Data for the Tower Of London Performance in Australian Midlife Women
Lee, Young Eun C., Anderson, Jacqueline F., Dennerstein, Lorraine, Henderson, Victor W. and Szoeke, Cassandra. (2013). Normative Data for the Tower Of London Performance in Australian Midlife Women. Australian Psychologist. https://doi.org/10.1111/ap.12033
Factors affecting subjective memory complaints in the AIBL aging study: Biomarkers, memory, affect, and age
Buckley, Rachel F., Saling, Michael M., Ames, David, Rowe, Christopher C., Lautenschlager, Nicola T., Macaulay, S. Lance, Martins, Ralph N., Masters, Colin L., O'Meara, T., Savage, Greg, Szoeke, Cassandra, Villemagne, Victor L. and Ellis, Kathryn A.. (2013). Factors affecting subjective memory complaints in the AIBL aging study: Biomarkers, memory, affect, and age. International Psychogeriatrics. https://doi.org/10.1017/S1041610213000665
Predicting Alzheimer disease with beta-amyloid imaging: Results from the Australian imaging, biomarkers, and lifestyle study of ageing
Rowe, Christopher C., Bourgeat, Pierrick, Ellis, Kathryn A., Brown, Belinda M., Lim, Yen Ying, Mulligan, Rachel, Jones, Gareth, Maruff, Paul Thomas, Woodward, Michael Clifford, Price, Roger Ian, Robins, Peter, Tochon-Danguy, Henri, O'Keefe, Graeme, Pike, Kerryn E., Yates, Patsy, Szoeke, Cassandra, Salvado, Olivier, Macaulay, S. Lance, O'Meara, Timothy, ... Villemagne, Victor L.. (2013). Predicting Alzheimer disease with beta-amyloid imaging: Results from the Australian imaging, biomarkers, and lifestyle study of ageing. Annals of Neurology. https://doi.org/10.1002/ana.24040
Cognitive consequences of high Aß amyloid in mild cognitive impairment and healthy older adults: Implications for early detection of alzheimer's disease
Lim, Yen Ying, Ellis, Kathryn A., Harrington, Karra J., Kamer, Adrian, Pietrzak, Robert H., Bush, Ashley I., Darby, David G., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Savage, Greg R., Szoeke, Cassandra, Villemagne, Victor L., Ames, David and Maruff, Paul Thomas. (2013). Cognitive consequences of high Aß amyloid in mild cognitive impairment and healthy older adults: Implications for early detection of alzheimer's disease. Neuropsychology. https://doi.org/10.1037/a0032321
Research and standardization in Alzheimer's trials: Reaching international consensus
Carillo, Maria C., Rowe, Christopher C., Szoeke, Cassandra, Masters, Colin L., Ames, David, O'Meara, Timothy, Macaulay, S Lance, Milner, Andrew, Ellis, Kathryn A., Maruff, Paul Thomas, Rainey-Smith, Stephanie R., Martins, Ralph N., Bain, Lisa J. and Head, Richard. (2013). Research and standardization in Alzheimer's trials: Reaching international consensus. Alzheimer's and Dementia. https://doi.org/10.1016/j.jalz.2012.10.006
Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-: Prodromal Alzheimer's disease?
Lim, Yen Ying, Ellis, Kathryn A., Harrington, Karra J., Pietrzak, Robert H., Gale, Joanne, Ames, David, Bush, Ashley I., -, David Darby, Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Savage, Greg, Szoeke, Cassandra, Villemagne, Victor L. and Maruff, Paul Thomas. (2013). Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-: Prodromal Alzheimer's disease? Journal of Alzheimer's Disease. https://doi.org/10.3233/JAD-121771
Three-month stability of the cogstate brief battery in healthy older adults, mild cognitive impairment, and alzheimer's disease: Results from the Australian imaging, biomarkers, and lifestyle-rate of change substudy (AIBL-ROCS)
Lim, Yen Ying, Jaeger, Judith, Harrington, Karra J., Ashwood, Tim J., Ellis, Kathryn A., Stoffler, Albrecht, Szoeke, Cassandra, -, Rebecca Lachovitzki, Martins, Ralph N., Villemagne, Victor L., Bush, Ashley I., Masters, Colin L., Rowe, Christopher C., Ames, David, Darby, David and Maruff, Paul Thomas. (2013). Three-month stability of the cogstate brief battery in healthy older adults, mild cognitive impairment, and alzheimer's disease: Results from the Australian imaging, biomarkers, and lifestyle-rate of change substudy (AIBL-ROCS). Archives of Clinical Neuropsychology. https://doi.org/10.1093/arclin/act021
Amyloid ß deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: A prospective cohort study
Villemagne, Victor L., Burnham, Samantha, Bourgeat, Pierrick, Brown, Belinda M., Ellis, Kathryn A., Salvado, Olivier, Szoeke, Cassandra, Macaulay, S. Lance, Martins, Ralph N., Maruff, Paul Thomas, Ames, David, Rowe, Christopher C. and Masters, Colin L.. (2013). Amyloid ß deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: A prospective cohort study. The Lancet Neurology. https://doi.org/10.1016/S1474-4422(13)70044-9
The association of ABeta amyloid and composite cognitive measures in healthy older adults and MCI
Harrington, Karra J., Lim, Yen Ying, Ellis, Kathryn A., Copolov, Carly, Darby, D, Weinborn, M., Ames, David, Martins, R. N., Savage, G., Szoeke, Cassandra, Rowe, C. C., Villemagne, V. L., Masters, C. L. and Maruff, Paul Thomas. (2013). The association of ABeta amyloid and composite cognitive measures in healthy older adults and MCI. International Psychogeriatrics. https://doi.org/10.1017/S1041610213001087
Increased risk of cognitive impairment in patients with diabetes is associated with metformin
Moore, Eileen, Mander, Alastair, Ames, David, Kotowicz, Mark A., Carne, Ross, Brodaty, Henry, Woodward, Michael Clifford, Boundy, Karen, Ellis, Kathryn A., Bush, Ashley I., Faux, Noel G., Martins, Ralph N., Szoeke, Cassandra, Rowe, Christopher C. and Watters, David. (2013). Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care. https://doi.org/10.2337/dc13-0229
Decline in cognitive function over 18 months in healthy older adults with high amyloid-beta
Ellis, Kathryn A., Lim, Yen Ying, Harrington, Karra J., Ames, David, Bush, Ashley I., Darby, David, Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Savage, Greg, Szoeke, Cassandra, Villemagne, Victor L. and Maruff, Paul Thomas. (2013). Decline in cognitive function over 18 months in healthy older adults with high amyloid-beta. Journal of Alzheimer's Disease. https://doi.org/10.3233/JAD-122170
Intense physical activity is associated with cognitive performance in the elderly
Brown, Belinda M., Peiffer, John, Sohrabi, Hamid R., Mondal, Alinda, Gupta, Veer B. A., Rainey-Smith, Stephanie R., Taddei, Kevin, Burnham, Samantha C., Ellis, Kathryn A., Szoeke, Cassandra, Masters, Colin L., Ames, David, Rowe, Christopher C. and Martins, Ralph N.. (2012). Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry. https://doi.org/10.1038/tp.2012.118
Oestrogen alpha-receptor variant and two-year memory decline in midlife Australian women
Bousman, Chad, Szoeke, Cassandra, Chen, Karen, Dennerstein, Lorraine, Henderson, Victor W. and Everall, Ian P.. (2012). Oestrogen alpha-receptor variant and two-year memory decline in midlife Australian women. Neuropsychobiology. https://doi.org/10.1159/000341879
Cortical surface mapping using topology correction, partial flattening and 3D shape context-based non-rigid registration for use in quantifying atrophy in Alzheimer's disease
Acosta, Oscar, Fripp, Jurgen, Dore, Vincent, Bourgeat, Pierrick, Favreau, Jean-Marie, Chetelat, Gael, Rueda, Andrea, Villemagne, Victor L., Szoeke, Cassandra, Ames, David, Ellis, Kathryn A., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Bonner, Erik, Gris, Florence, Xiao, Di, Raniga, Parnesh, Barra, Vincent and Salvado, Olivier. (2012). Cortical surface mapping using topology correction, partial flattening and 3D shape context-based non-rigid registration for use in quantifying atrophy in Alzheimer's disease. Journal of Neuroscience Methods. https://doi.org/10.1016/j.jneumeth.2011.12.011
Blood-based protein biomarkers for diagnosis of Alzheimer disease
Doecke, James D., Laws, Simon M., Faux, Noel G., Wilson, William, Burnham, Samantha, Lam, Chiou Peng, Mondal, Alinda, Bedo, Justin, Bush, Ashley I., Brown, Belinda M., De Ruyck, Karl, Ellis, Kathryn A., Fowler, Christopher J., Gupta, V. B., Head, Richard, Macaulay, S. Lance, Pertile, Kelly K., Rowe, Christopher C., Rembach, Alan R., ... Martins, Ralph N.. (2012). Blood-based protein biomarkers for diagnosis of Alzheimer disease. Archives of Neurology. https://doi.org/10.1001/archneurol.2012.1282
Predictors of rapid cognitive decline in Alzheimer's disease: Results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing
Sona, Alessano, Zhang, Ping, Ames, David, Bush, Ashley I., Lautenschlager, Nicola T., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Szoeke, Cassandra, Taddei, Kevin and Ellis, Kathryn A.. (2012). Predictors of rapid cognitive decline in Alzheimer's disease: Results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing. International Psychogeriatrics. https://doi.org/10.1017/S1041610211001335
Hormone levels and cognitive function in postmenopausal midlife women
Ryan, Joanne L., Stanczyk, Frank Z., Dennerstein, Lorraine, Mack, Wendy J., Clark, Margaret S., Szoeke, Cassandra, Kildea, Daniel George and Henderson, Victor W.. (2012). Hormone levels and cognitive function in postmenopausal midlife women. Neurobiology of Aging. 33(3), pp. 617.e11 - 617.e22. https://doi.org/10.1016/j.neurobiolaging.2010.07.014
Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults
Lim, Yen Ying, Ellis, Kathryn A., Pietrzak, Robert H., Ames, David, Darby, David, Harrington, Karra J., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Savage, Greg, Szoeke, Cassandra, Villemagne, Victor L. and Maruff, Paul Thomas. (2012). Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults. Neurology. https://doi.org/10.1212/WNL.0b013e31826e9ae6
Use of the CogState Brief Battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study
Lim, Yen Ying, Ellis, Kathryn A., Harrington, Karra J., Ames, David, Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Savage, Greg, Szoeke, Cassandra, Darby, David and Maruff, Paul Thomas. (2012). Use of the CogState Brief Battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Journal of Clinical and Experimental Neuropsychology. https://doi.org/10.1080/13803395.2011.643227
Adherence to a Mediterranean diet and Alzheimer's disease risk in an Australian population
Gardener, Samantha L., Gu, Yian, Rainey-Smith, Stephanie R., Keogh, Jennifer B., Clifton, Peter Marshall, Mathieson, S. L., Taddei, Kevin, Mondal, Alinda, Ward, Vanessa K., Scarmeas, Nikolaos, Barnes, Margaret, Ellis, Kathryn A., Head, Richard, Masters, Colin L., Ames, David, Macaulay, Stuart Lance, Rowe, Christopher C., Szoeke, Cassandra and Martins, Ralph N.. (2012). Adherence to a Mediterranean diet and Alzheimer's disease risk in an Australian population. Translational Psychiatry. https://doi.org/10.1038/tp.2012.91
Cognition and beta-amyloid in preclinical Alzheimer's disease: Data from the AIBL study
Pike, Kerryn E., Ellis, Kathryn A., Villemagne, Victor L., Good, Norm, Chetelat, Gael, Ames, David, Szoeke, Cassandra, Laws, Simon M., Verdile, Giuseppe, Martins, Ralph N., Masters, Colin L. and Rowe, Christopher C.. (2011). Cognition and beta-amyloid in preclinical Alzheimer's disease: Data from the AIBL study. Neuropsychologia. https://doi.org/10.1016/j.neuropsychologia.2011.04.012
Advances in structural and molecular neuroimaging in Alzheimer's disease
Ellis, Kathryn A., Rowe, Christopher C., Szoeke, Cassandra E. I., Villemagne, Victor L., Ames, David, Chetelat, Gael, Martins, Ralph N., Masters, Colin L., Fripp, Jurgen, Acosta, Oscar, Raniga, Parnesh, Bourgeat, Pierrick T. and Salvado, Olivier. (2011). Advances in structural and molecular neuroimaging in Alzheimer's disease. Medical Journal of Australia.
Effects of anticholinergic drugs on cognitive function in older Australians: Results from the AIBL study
Sittironnarit, Gobhathai, Ames, David, Bush, Ashley I., Faux, Noel G., Flicker, Leon, Foster, Jonathan, Hilmer, Sarah, Lautenschlager, Nicola T., Maruff, Paul Thomas, Masters, Colin L., Martins, Ralph N., Rowe, Christopher C., Szoeke, Cassandra and Ellis, Kathryn A.. (2011). Effects of anticholinergic drugs on cognitive function in older Australians: Results from the AIBL study. Dementia and Geriatric Cognitive Disorders. https://doi.org/10.1159/000325171
Plasma apolipoprotein E and Alzheimer disease risk: The AIBL study of aging
Gupta, V. B., Laws, Simon M., Villemagne, Victor L., Ames, David, Bush, Ashley I., Ellis, Kathryn A., Lui, J. K., Masters, Colin L., Rowe, Christopher C., Szoeke, Cassandra, Taddei, K. and Martins, Ralph N.. (2011). Plasma apolipoprotein E and Alzheimer disease risk: The AIBL study of aging. Neurology. https://doi.org/10.1212/WNL.0b013e318211c352
Association of plasma Aß peptides with blood pressure in the elderly
Lambert, Jean C., Dallongeville, Jean, Ellis, Kathryn A., Schraen-Maschke, Susanna, Lui, James, Laws, Simon M., Dumont, Julie, Richard, Florence, Cottel, Dominique C., Berr, Claudine, Ames, David, Masters, Colin L., Rowe, Christopher C., Szoeke, Cassandra, Tzourio, Christophe, Dartigues, Jean-Francois, Buee, Luc, Martins, Ralph N. and Amouyel, Phillippe. (2011). Association of plasma Aß peptides with blood pressure in the elderly. PLoS ONE. 6(4), pp. 1 - 6. https://doi.org/10.1371/journal.pone.0018536
Executive functions in recently postmenopausal women: Absence of strong association with serum gonadal steroids
Ryan, Joanne L., Stanczyk, Frank Z., Dennerstein, Lorraine, Mack, Wendy J., Clark, Margaret S., Szoeke, Cassandra and Henderson, Victor W.. (2011). Executive functions in recently postmenopausal women: Absence of strong association with serum gonadal steroids. Brain Research. https://doi.org/10.1016/j.brainres.2010.10.093
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: Baseline characteristics in subjects of the Australian imaging biomarker lifestyle study
Faux, Noel G., Ellis, Kathryn A., Porter, Lorine, Fowler, Chris J., Laws, Simon M., Martins, Ralph N., Pertile, Kelly K., Rembach, Alan R., Rowe, Christopher C., Rumble, Rebecca L., Szoeke, Cassandra, Taddei, Kevin, Taddei, Tania, Trounson, Brett, Villemagne, Victor L., Ward, Vanessa R., Ames, David, Masters, Colin L. and Bush, Ashley I.. (2011). Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: Baseline characteristics in subjects of the Australian imaging biomarker lifestyle study. Journal of Alzheimer's Disease. https://doi.org/10.3233/JAD-2011-110752
A web-based normative data tool for assessing cognitive performance in healthy older Australians
McBride, Simon J., Szoeke, Cassandra E. I., Good, Norm M., Ames, David, Martins, Ralph N., Masters, Colin L., Maruff, Paul Thomas, Rowe, Christopher C., Savage, Greg and Ellis, Kathryn A.. (2011). A web-based normative data tool for assessing cognitive performance in healthy older Australians. Medical Journal of Australia.
Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease
Chetelat, Gael, Villemagne, Victor L., Pike, Kerryn E., Ellis, Kathryn A., Bourgeat, Pierrick, Jones, Gareth, O'Keefe, Graeme, Salvado, Olivier, Szoeke, Cassandra, Martins, Ralph N., Ames, David, Masters, Colin L. and Rowe, Christopher C.. (2011). Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease. Brain. 134(3), pp. 798 - 807. https://doi.org/10.1093/brain/awq383