Analysis method and system

A method and system for analysing a sample comprising a first material and a second material of generally different densities and having a junction therebetween. The method 5 comprises: defining automatically a plurality of regions of interest within an image of the sample, each of said regions of interest having a width of one or more voxels or pixels; determining respective density, intensity or attenuation profiles within the regions of interest; determining a location of said junction including defining a first reference point within one of said first and second materials and employing the first reference point as current reference 10 point, and (i) determining a closest point to said current reference point that is on said respective profile and in the other of said first and second materials to that of the current reference point; (ii) locating a greatest difference in values of the respective profile between an adjacent peak and trough in a segment of the respective profile between said current reference point and said closest point; and (iii) locating a point of inflexion in said segment. 6631096_1 (GHMatters) P82011.AU.2 AJM Memory RAM EPROM Mass storage device 34 Figure 3 28 Processing controller Processor 22 ROI result storage - 70 32 Display 42 ** controller File result storage 72 User DICOM interface file poller DICOM file 46 Density converter profile 58 File 48 analyzer selector ROI 60 File 50 rejecter digitizer Initial result 62 ROI 52 integrator selector Final result 64 Bone 54 integrator 64 identifier determiner 66 Specimen 56 eut position Result 68 adjuster output 6 Figure 4