Willingness, preferred ways and potential barriers to use pre-exposure prophylaxis for HIV prevention among men who have sex with men in China

Journal article

Yu, Simin, Cross, Wendy, Lam, Louisa Lok Yi, Zhang, Kaili, Banik, Biswajit, Li, Xianhong and Wang, Honghong. (2021). Willingness, preferred ways and potential barriers to use pre-exposure prophylaxis for HIV prevention among men who have sex with men in China. BMJ Open. 11(10), p. Article e053634. https://doi.org/10.1136/bmjopen-2021-053634
AuthorsYu, Simin, Cross, Wendy, Lam, Louisa Lok Yi, Zhang, Kaili, Banik, Biswajit, Li, Xianhong and Wang, Honghong
Abstract

Objective
To explore willingness and preferred ways to use HIV pre-exposure prophylaxis (PrEP), factors associated with willingness, and potential barriers to PrEP use among men who have sex with men (MSM) in Changsha, China.

Design
A cross-sectional survey was conducted from 25 June to 31 August 2019. Two hundred and fifty-five MSM were recruited from three community-based organisations (CBOs) in Changsha City. Willingness and potential barriers to use PrEP were examined using researcher-created scales. Univariate and multivariate logistic regression was used to analyse the factors associated with willingness to use PrEP. P values <0.05 were considered significant.

Setting
Three MSM inclusive CBOs in Changsha, Hunan Province, China.

Participants
255 HIV-negative MSM were recruited through their CBOs with snowball sampling.

Results
Less than half of the participants (43.1%) had heard of PrEP and 15.3% were willing to use PrEP. The participants reported higher willingness to use event-driven PrEP (3.70±0.07) than daily PrEP (2.65±0.07). Higher self-rated risk and fear of contracting HIV (OR: 14.47, 95% CI 2.19 to 95.53), awareness of PrEP (OR: 4.20, 95% CI 1.64 to 10.73), sharing one’s own sexual orientation with parents or siblings (OR: 2.52, 95% CI 1.54 to 7.20) and having a university education or above (OR:0.29, 95% CI 0.12 to 0.72) were associated with willingness to use PrEP. Only 12.2% of the sample was concerned about potential barriers to PrEP use.

Conclusion
Efforts to improve awareness and knowledge of PrEP, teach self-evaluation of HIV infection risk and provide social and emotional support for MSM are needed to scale up PrEP implementation in China.

Year2021
JournalBMJ Open
Journal citation11 (10), p. Article e053634
PublisherBMJ Publishing Group
ISSN2044-6055
Digital Object Identifier (DOI)https://doi.org/10.1136/bmjopen-2021-053634
PubMed ID34716167
Scopus EID2-s2.0-85118721103
PubMed Central IDPMC8559123
Open accessPublished as ‘gold’ (paid) open access
Page range1-10
FunderPhilosophy and Social Science Foundation of Hunan Province
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online29 Oct 2021
Publication process dates
Accepted14 Oct 2021
Deposited09 Aug 2023
Grant ID16YBA365
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