A primer on incorporating sex as a biological variable into the conduct and reporting of basic and clinical research studies
Journal article
Denfeld, Quin E., Lee, Christopher S. and Habecker, Beth A.. (2022). A primer on incorporating sex as a biological variable into the conduct and reporting of basic and clinical research studies. American Journal of Physiology: Heart and Circulatory Physiology. 322(3), pp. H350-H354. https://doi.org/10.1152/ajpheart.00605.2021
Authors | Denfeld, Quin E., Lee, Christopher S. and Habecker, Beth A. |
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Abstract | The recent move to require sex as a biological variable (SABV), which includes gender, into the reporting of research published by the American Journal of Physiology-Heart and Circulatory Physiology follows a growing, and much-needed, trend by journals. Understandably, there is concern over how to do this without adding considerable work, especially if one’s primary research focus is not on elucidating sex/gender differences. The purpose of this article is to provide additional guidance and examples on how to incorporate SABV into the conduct and reporting of basic and clinical research. Using examples from our research, which includes both studies focused and not focused on sex/gender differences, we offer suggestions for how to incorporate SABV into basic and clinical research studies. Listen to this article’s corresponding podcast at https://ajpheart.podbean.com/e/incorporating-sex-as-a-biological-var... |
Keywords | cardiovascular; gender; heart failure; sex; study design |
Year | 2022 |
Journal | American Journal of Physiology: Heart and Circulatory Physiology |
Journal citation | 322 (3), pp. H350-H354 |
Publisher | American Physiological Society |
ISSN | 0363-6135 |
Digital Object Identifier (DOI) | https://doi.org/10.1152/ajpheart.00605.2021 |
PubMed ID | 35030071 |
Scopus EID | 2-s2.0-85124437130 |
PubMed Central ID | PMC8836716 |
Page range | H350-H354 |
Funder | National Institutes of Health (NIH), United States of America |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 08 Feb 2022 |
01 Mar 2022 | |
Publication process dates | |
Accepted | 12 Jan 2022 |
Deposited | 21 Sep 2023 |
Grant ID | HD043488 |
NR019054 | |
HL093056 | |
HL146833 | |
NR013492 |
https://acuresearchbank.acu.edu.au/item/8zq3q/a-primer-on-incorporating-sex-as-a-biological-variable-into-the-conduct-and-reporting-of-basic-and-clinical-research-studies
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