An introductory guide to conducting the Trier Social Stress Test
Journal article
Labuschagne, Izelle, Grace, Caitlin, Rendell, Peter, Terrett, Gillian and Heinrichs, Markus. (2019). An introductory guide to conducting the Trier Social Stress Test. Neuroscience and Biobehavioral Reviews. 107, pp. 686-695. https://doi.org/10.1016/j.neubiorev.2019.09.032
Authors | Labuschagne, Izelle, Grace, Caitlin, Rendell, Peter, Terrett, Gillian and Heinrichs, Markus |
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Abstract | The Trier Social Stress Test (TSST) is a reliable biopsychological tool to examine the effects of acute stress on psychological and physiological functioning in humans. While the TSST reliably increases hypothalamic-pituitary-adrenal axis activation, amongst other biomarkers, through a combination of social evaluative threat and uncontrollability, the original protocol is limited in methodological detail that has impacted its reproducibility. Although many studies include a mock job interview and surprise arithmetic task, there are large variations in the timing of events, the number and method of biological (e.g., cortisol) sampling, the administration of a glucose drink, set-up of equipment and rooms, panel composition, and panel interaction with participants. We provide an overview of the potential impact of methodological variations on the stress (cortisol) response. Importantly, we also provide a step-by-step guide as a laboratory manual on how to conduct the TSST. This introductory guide may be a useful and time-saving resource that may also improve the scientific standard and reliability of the reported psychobiological stress effects in future studies. |
Keywords | cortisol; HPA axis; humans; public speaking; mental arithmetic; TSST |
Year | 2019 |
Journal | Neuroscience and Biobehavioral Reviews |
Journal citation | 107, pp. 686-695 |
Publisher | Elsevier Ltd |
ISSN | 0149-7634 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.neubiorev.2019.09.032 |
PubMed ID | 31560923 |
Scopus EID | 2-s2.0-85073449925 |
Page range | 686-695 |
Funder | Australian Catholic University (ACU) |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 24 Sep 2019 |
Publication process dates | |
Accepted | 21 Sep 2019 |
Deposited | 03 Nov 2023 |
https://acuresearchbank.acu.edu.au/item/8zy29/an-introductory-guide-to-conducting-the-trier-social-stress-test
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